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The map label for this gene is apxIA [H]

Identifier: 78189872

GI number: 78189872

Start: 2436941

End: 2441521

Strand: Reverse

Name: apxIA [H]

Synonym: Cag_1919

Alternate gene names: 78189872

Gene position: 2441521-2436941 (Counterclockwise)

Preceding gene: 78189873

Following gene: 78189871

Centisome position: 94.92

GC content: 42.7

Gene sequence:

>4581_bases
ATGGCTGATTTTATTACGCTCAGTAATCCAAGCTATAGCTACAATGCCTCTAAGGGAAAAACAACAGTACAGTTTGATAT
TTGTTTCGCATCAAATGAAATGGCAGGCTCTAAAATAACGGGAGCAAAAATTGACCTTCAGTATAATACGTCACTTGTAA
CTGCATATCAGATAACTAATCCAACATTTTCGTTTGAAGGTGATTTTGGAACAGAAACAGCATCAGTTTGGGTAGCAGCT
TTTGATCAAACTGCAAATTTAACGGGTAGTGGTGCTACAGGTCAAATAGCCATGTTGGCGACTAGTAATGATGCCAATCC
AATTATAGTAAATGGTAAAGTGCTTACGGTTACTTTAAGCGTTACAGGTGAAGTTAATGCGGATACCTTTGCTATTACGT
TACAAAAAACAGCAGATGGTGGTAATAACAGTATTTCAAATGCTACGACAGAATATTTTCTTGATGGTGGTACTTATGTA
GCACCCCCAACAAGTTTAGCTGACGTTACCGTTGACCTGCATGTAAATAGCGATACCGGTACCTCAAATACTGATAATCT
GACCAATGATGATACTCCAACAGTAACGGTTAACTTGACCGGTAAATCGTTATCTGAGGGTCAAACACTTCAAATTATTG
ACACATCAAATAGTAATGCCGTTGTTGGTACTTATACGATTACTTCGACTGACGCAACCAACGGTATTACAACAAAAGAT
GTTACGCTTAGCACCTTGACAAGTGGGGCTCACGCGCTTAAAGCACAACTAAATGCTGGTTCGACGGCTGGTACCCCAAG
TGCAACAGCTACAACGGTAACCATTGATACTACCGCACCAACAAGTTTAGCAGACGTGCCTGTGGATTTAAAAAGTTCAA
GCGATAGTGGTTTAAGTACCGATAATATTACTAATGCGACAACTCCTGTAATAACTGTTAATCTGACGGGAAAAACTCTT
GTTGCTGGTGATATTGTACAGGTTATAGATACGAGTAATGGAAATGCTGTTGTTGGTTCTTATACTGTTACCACTGGCGG
TACAGGTTCATCATTAGATATTACGTTAACGACTCCATTAAGCTTAGGTGCTCATGCCCTCAAAGCTCAATTAGTGGATG
TAGCCGGTAATGTTGGAACTGCAAGTACTAATGCTTTAACTGTTACTGTTGATACCACTGCACCAACGGCTCCAACGTTA
GCGCTAGCAACAGATAGTGGTAGCAGCAATAGCGATGGTATTACCAATGTTGGTACGGTCAATGTTACAGGCATAGAAAC
GAATGCAACGTGGCAATACAGCACGAATGGTGGAACAAATTGGAGTAATGGTACGGGCACAAGTTTTACGTTAGCTGCCG
CAACTTATGCGGTTGATGCAATTCGAGTTCGTCAGACAGATGTAGCCGGCAATGTGAGCGGTGAAGGTAAAATTGCAACA
GCAGTAACCATTGATAGCTCTGCACCGGTAGCACCCACGTTAGCATTTACCGATGCCGGTACAAGTACAACCGATGGACA
TACCAGCAATAATACGATTACGGTTACCGGTATCGAAAGCAACGCAACGTGGCAATACAGTACGAATGGTGGTACAAATT
GGAGTAATGGTACTGGCACAAGCTTTACTATAGTTGATGGCACTTACAATGCTAACACTATTAAGGTAAAGCAAACGGAT
GTAGCTGGTAATGTAAGTGGCGAAGGTTCTCTTGCCCCAGCAATTACCGTTGATACAGTACGTCCCACAGTCACTGTTAC
TCCAGTAACAACGGCGTTATCTGCTCAGGGTACGACTACCATTACCATGACTATGAGCGAAGCCGTTACAGGATTCGCTG
CTGATGATATCAAAACATCATCAAAATATTCGATTTCCAATTTTAGTGCTACTTCATCAACAGTTTATACTGCTACATAC
ACAGCTAATGAGGCAACTACTGATGTAGCAAAAGAGCTAAAATTCGAGACAAATTGGACTGACGCTGCTGGTAACCAACC
AAAATTTGGTCCAACTGTTGATATTACCTTAAACGACGCTGCATTAAAAATCGGCGAAACAGCTACAGTAACCTTTACAT
TTAGTGAAGTTCCAACTGGTTTTGATTCAAGCGATATATCGGTAACCAACGCCAATGGTCAGCTTAGCGGTTTAGCAGTA
AAATCAGGTTCAAATGGTTTAGTGTATGAAGCAACATTTACTCCTACAGCTAATGTTACAAGTGCAACAAATAAGATTAC
CGTAGGAAAAGATTGGACAAATGCAGAAGGGGTCGCTCCAACGAATGATACAACTGATTCCCCCAATTATGCGGTAGATA
CATTCCGTCCCACAGCCACCATTGTTGTAGCAGATATAGCCTTAAAAGCGGGAGAAACATCATTAGTTACTATTACTTTC
AGTGAAGCAGTTAGCGGTTTTGATAACGCTGATCTCACCATCCAGAATGGAACTCTTACGAATGTTGCATCGTCTGACGG
AGGCATTACATGGTCAGCAACACTAACACCAACGGCAGATATTTCTGATACAACAAACGTTATCACGTTAGCCAATACCG
GTGTCAATGATGTTGCCGGGAATGCAGGTACGGGTACAACGGATTCTAATAATTATGCGATAGATACAGCTCGTCCTACG
GCCACCATTGTTGTAGCTGATACAGCACTCAAGGCAGGAGAAACATCCGCAGTTACCATTACCTTTAGTGAAGCTGTTAC
AGGATTTGATAACAGTGATCTTACCATTGCAAATGGTACACTCACCCCTGTAGCGTCAAGTGATGGAGGAATAACATGGA
CAGCAACGTTAACGCCAACCACAAATCTTGAAGATGCCACCAATGTTATCACTGTCAATAAAGCAGGAGTAACCGATGCC
GCCGGTAATGCCGGAGTTAGCACAACGGATTCCAATAATTACACAATCGACACTCAAGCTCCGGCAGCGCCAACTTTATC
AATCACAGATAATGGACAGAGTACATCGGATAATCTTACTAACAATGGAACGGTAACTGTAAGCGGTCTTGAAACCGGTG
CAACATGGCAGTATAGCACAAATGGCGGTACTAACTGGACGACTGGTTCAGGCACAAGTTTCACGTTAGGAGCTGGAACG
TATGCAGCAAATAACATTCAGGTAAAGCAAACCGATGCAGCAGGAAACGTTGGTATTGTTGGTCAAATTACCTCACAGGT
TGATGTTGATAAGGTTGCACCTACTTTAAAAAGTGTTGTTGTAAATGGTACATCTGTAGTAATCACCTATAATGAAGCGC
TTGATGCCACCAATAAGCCAGCAACAACTGATTTTACTGTATCCAATAATACAGTTAACAATGTGGCTGTTGATTCGACA
GCTAAAACCGTTACGTTAACGCTTGGAACAACAGTCGTATCAGGGGCAGATGTAACTGTAAGTTACGCTGATCCAACCAC
TGTAGATGATAGCAACGCTATTCAAGATGTTGCGGGCAATGATGCGGCTAAGTTTACCACAACTATAAGTGGCACAAAAA
CTACAACAAAAGTAGAAGTACCGCAATCATCTACCGCTGTTAACAATATTCCAATTGGCACGAATGCGGCGGGTAATCCT
GTTATACAACTTGATATTCCTGCTAATGTAGATGTTATTGCAAAGGAAGTTACAGACACTAATGCTACCACGTTAACGGA
TAAGCTTAATGATTCGCTTGACGCATTAACGACAGCATCTACAGGACAAATTGATTCCATAGCGGTGCAAACTGGGATTG
ATAACTACGTTGCAACACTATCAACGCCAGACCAAGCCAATGTTGTGGTGCGTACATTGGAGTTAAAATCTGCAAATGCA
ACAACGGGTGCAGAACTTGTAGTTACTGGTAATAGCGCAATCGGTAGTAATGAAGCGCTTGTTATTGATACTCGTGGTCT
TCAACCAGGCTCAGTCCTTAACCTTGAAAATGTTGAGTTTGCCATTATTATCGGTGATAACGTTACCATTCGTGGCGGTG
ATGGTGCGAATATTGTGTATGCTGGAGCTGGTCGCCAAGATATTAAACTTGGAGATGAATCGGATACCTTACATGGTGGT
ACAGGCGACGATATTGTAGCATCTGAGGGTGGTGACGACTGGCTTTATGGCGACGATGGAAACGATACTGTAAGCGGTGG
TGCCGATAACGACCATCTTTTTGGCGGTACAGGTGACGATTCGCTTGATGGTGGCACGGGTAACGACACTCTTGATGGTG
GTGACGGTAATGATATGCTCAATGGTGGTACGGGTAACGATGTGTTTACTGGTGGGGTAGGCACCGATACCATCCAATTT
GCAGGATTATTTAGCAACTACACGATTACCTATAATCCTGGTGCTCATCAGTACGTGTTAACTGATACAACAGGTGCGAC
TAAAACGGTGTCGAGTACCGATTTTGAACTCTTTAGCTTCACAGATGGTGTAAAGAGTGATGATGATGTGTATGCGGTTG
CTGCAAATCCTTATGGTCAACCGGAACACATTATCGCCAACGATCCTGCATTTGTAGGCGTTGCAGGTCTTGGCTTAATT
GCAGCCCTGCTCTTCTTGTAA

Upstream 100 bases:

>100_bases
GATGTTGATGGCTCATGGGTCAATTTGCATTAATGCAATAATTTTTTTAACGCCTTATTAGAAGATAGGCTTAACCTTAA
ATTAAAGGAGTAAAAATACA

Downstream 100 bases:

>100_bases
ATCCGCATTACTTTCCATTTCCCTTCTTTCAAAAGCCGAGCGTGCGCCACAAGCACCCTCGGCTTTTATTTTGTTATGGT
GTAAAAGTTTTGCCTTAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: APX-IA; ApxI; Cytolysin IA; CLY-IA; Hemolysin IA; HLY-IA [H]

Number of amino acids: Translated: 1526; Mature: 1525

Protein sequence:

>1526_residues
MADFITLSNPSYSYNASKGKTTVQFDICFASNEMAGSKITGAKIDLQYNTSLVTAYQITNPTFSFEGDFGTETASVWVAA
FDQTANLTGSGATGQIAMLATSNDANPIIVNGKVLTVTLSVTGEVNADTFAITLQKTADGGNNSISNATTEYFLDGGTYV
APPTSLADVTVDLHVNSDTGTSNTDNLTNDDTPTVTVNLTGKSLSEGQTLQIIDTSNSNAVVGTYTITSTDATNGITTKD
VTLSTLTSGAHALKAQLNAGSTAGTPSATATTVTIDTTAPTSLADVPVDLKSSSDSGLSTDNITNATTPVITVNLTGKTL
VAGDIVQVIDTSNGNAVVGSYTVTTGGTGSSLDITLTTPLSLGAHALKAQLVDVAGNVGTASTNALTVTVDTTAPTAPTL
ALATDSGSSNSDGITNVGTVNVTGIETNATWQYSTNGGTNWSNGTGTSFTLAAATYAVDAIRVRQTDVAGNVSGEGKIAT
AVTIDSSAPVAPTLAFTDAGTSTTDGHTSNNTITVTGIESNATWQYSTNGGTNWSNGTGTSFTIVDGTYNANTIKVKQTD
VAGNVSGEGSLAPAITVDTVRPTVTVTPVTTALSAQGTTTITMTMSEAVTGFAADDIKTSSKYSISNFSATSSTVYTATY
TANEATTDVAKELKFETNWTDAAGNQPKFGPTVDITLNDAALKIGETATVTFTFSEVPTGFDSSDISVTNANGQLSGLAV
KSGSNGLVYEATFTPTANVTSATNKITVGKDWTNAEGVAPTNDTTDSPNYAVDTFRPTATIVVADIALKAGETSLVTITF
SEAVSGFDNADLTIQNGTLTNVASSDGGITWSATLTPTADISDTTNVITLANTGVNDVAGNAGTGTTDSNNYAIDTARPT
ATIVVADTALKAGETSAVTITFSEAVTGFDNSDLTIANGTLTPVASSDGGITWTATLTPTTNLEDATNVITVNKAGVTDA
AGNAGVSTTDSNNYTIDTQAPAAPTLSITDNGQSTSDNLTNNGTVTVSGLETGATWQYSTNGGTNWTTGSGTSFTLGAGT
YAANNIQVKQTDAAGNVGIVGQITSQVDVDKVAPTLKSVVVNGTSVVITYNEALDATNKPATTDFTVSNNTVNNVAVDST
AKTVTLTLGTTVVSGADVTVSYADPTTVDDSNAIQDVAGNDAAKFTTTISGTKTTTKVEVPQSSTAVNNIPIGTNAAGNP
VIQLDIPANVDVIAKEVTDTNATTLTDKLNDSLDALTTASTGQIDSIAVQTGIDNYVATLSTPDQANVVVRTLELKSANA
TTGAELVVTGNSAIGSNEALVIDTRGLQPGSVLNLENVEFAIIIGDNVTIRGGDGANIVYAGAGRQDIKLGDESDTLHGG
TGDDIVASEGGDDWLYGDDGNDTVSGGADNDHLFGGTGDDSLDGGTGNDTLDGGDGNDMLNGGTGNDVFTGGVGTDTIQF
AGLFSNYTITYNPGAHQYVLTDTTGATKTVSSTDFELFSFTDGVKSDDDVYAVAANPYGQPEHIIANDPAFVGVAGLGLI
AALLFL

Sequences:

>Translated_1526_residues
MADFITLSNPSYSYNASKGKTTVQFDICFASNEMAGSKITGAKIDLQYNTSLVTAYQITNPTFSFEGDFGTETASVWVAA
FDQTANLTGSGATGQIAMLATSNDANPIIVNGKVLTVTLSVTGEVNADTFAITLQKTADGGNNSISNATTEYFLDGGTYV
APPTSLADVTVDLHVNSDTGTSNTDNLTNDDTPTVTVNLTGKSLSEGQTLQIIDTSNSNAVVGTYTITSTDATNGITTKD
VTLSTLTSGAHALKAQLNAGSTAGTPSATATTVTIDTTAPTSLADVPVDLKSSSDSGLSTDNITNATTPVITVNLTGKTL
VAGDIVQVIDTSNGNAVVGSYTVTTGGTGSSLDITLTTPLSLGAHALKAQLVDVAGNVGTASTNALTVTVDTTAPTAPTL
ALATDSGSSNSDGITNVGTVNVTGIETNATWQYSTNGGTNWSNGTGTSFTLAAATYAVDAIRVRQTDVAGNVSGEGKIAT
AVTIDSSAPVAPTLAFTDAGTSTTDGHTSNNTITVTGIESNATWQYSTNGGTNWSNGTGTSFTIVDGTYNANTIKVKQTD
VAGNVSGEGSLAPAITVDTVRPTVTVTPVTTALSAQGTTTITMTMSEAVTGFAADDIKTSSKYSISNFSATSSTVYTATY
TANEATTDVAKELKFETNWTDAAGNQPKFGPTVDITLNDAALKIGETATVTFTFSEVPTGFDSSDISVTNANGQLSGLAV
KSGSNGLVYEATFTPTANVTSATNKITVGKDWTNAEGVAPTNDTTDSPNYAVDTFRPTATIVVADIALKAGETSLVTITF
SEAVSGFDNADLTIQNGTLTNVASSDGGITWSATLTPTADISDTTNVITLANTGVNDVAGNAGTGTTDSNNYAIDTARPT
ATIVVADTALKAGETSAVTITFSEAVTGFDNSDLTIANGTLTPVASSDGGITWTATLTPTTNLEDATNVITVNKAGVTDA
AGNAGVSTTDSNNYTIDTQAPAAPTLSITDNGQSTSDNLTNNGTVTVSGLETGATWQYSTNGGTNWTTGSGTSFTLGAGT
YAANNIQVKQTDAAGNVGIVGQITSQVDVDKVAPTLKSVVVNGTSVVITYNEALDATNKPATTDFTVSNNTVNNVAVDST
AKTVTLTLGTTVVSGADVTVSYADPTTVDDSNAIQDVAGNDAAKFTTTISGTKTTTKVEVPQSSTAVNNIPIGTNAAGNP
VIQLDIPANVDVIAKEVTDTNATTLTDKLNDSLDALTTASTGQIDSIAVQTGIDNYVATLSTPDQANVVVRTLELKSANA
TTGAELVVTGNSAIGSNEALVIDTRGLQPGSVLNLENVEFAIIIGDNVTIRGGDGANIVYAGAGRQDIKLGDESDTLHGG
TGDDIVASEGGDDWLYGDDGNDTVSGGADNDHLFGGTGDDSLDGGTGNDTLDGGDGNDMLNGGTGNDVFTGGVGTDTIQF
AGLFSNYTITYNPGAHQYVLTDTTGATKTVSSTDFELFSFTDGVKSDDDVYAVAANPYGQPEHIIANDPAFVGVAGLGLI
AALLFL
>Mature_1525_residues
ADFITLSNPSYSYNASKGKTTVQFDICFASNEMAGSKITGAKIDLQYNTSLVTAYQITNPTFSFEGDFGTETASVWVAAF
DQTANLTGSGATGQIAMLATSNDANPIIVNGKVLTVTLSVTGEVNADTFAITLQKTADGGNNSISNATTEYFLDGGTYVA
PPTSLADVTVDLHVNSDTGTSNTDNLTNDDTPTVTVNLTGKSLSEGQTLQIIDTSNSNAVVGTYTITSTDATNGITTKDV
TLSTLTSGAHALKAQLNAGSTAGTPSATATTVTIDTTAPTSLADVPVDLKSSSDSGLSTDNITNATTPVITVNLTGKTLV
AGDIVQVIDTSNGNAVVGSYTVTTGGTGSSLDITLTTPLSLGAHALKAQLVDVAGNVGTASTNALTVTVDTTAPTAPTLA
LATDSGSSNSDGITNVGTVNVTGIETNATWQYSTNGGTNWSNGTGTSFTLAAATYAVDAIRVRQTDVAGNVSGEGKIATA
VTIDSSAPVAPTLAFTDAGTSTTDGHTSNNTITVTGIESNATWQYSTNGGTNWSNGTGTSFTIVDGTYNANTIKVKQTDV
AGNVSGEGSLAPAITVDTVRPTVTVTPVTTALSAQGTTTITMTMSEAVTGFAADDIKTSSKYSISNFSATSSTVYTATYT
ANEATTDVAKELKFETNWTDAAGNQPKFGPTVDITLNDAALKIGETATVTFTFSEVPTGFDSSDISVTNANGQLSGLAVK
SGSNGLVYEATFTPTANVTSATNKITVGKDWTNAEGVAPTNDTTDSPNYAVDTFRPTATIVVADIALKAGETSLVTITFS
EAVSGFDNADLTIQNGTLTNVASSDGGITWSATLTPTADISDTTNVITLANTGVNDVAGNAGTGTTDSNNYAIDTARPTA
TIVVADTALKAGETSAVTITFSEAVTGFDNSDLTIANGTLTPVASSDGGITWTATLTPTTNLEDATNVITVNKAGVTDAA
GNAGVSTTDSNNYTIDTQAPAAPTLSITDNGQSTSDNLTNNGTVTVSGLETGATWQYSTNGGTNWTTGSGTSFTLGAGTY
AANNIQVKQTDAAGNVGIVGQITSQVDVDKVAPTLKSVVVNGTSVVITYNEALDATNKPATTDFTVSNNTVNNVAVDSTA
KTVTLTLGTTVVSGADVTVSYADPTTVDDSNAIQDVAGNDAAKFTTTISGTKTTTKVEVPQSSTAVNNIPIGTNAAGNPV
IQLDIPANVDVIAKEVTDTNATTLTDKLNDSLDALTTASTGQIDSIAVQTGIDNYVATLSTPDQANVVVRTLELKSANAT
TGAELVVTGNSAIGSNEALVIDTRGLQPGSVLNLENVEFAIIIGDNVTIRGGDGANIVYAGAGRQDIKLGDESDTLHGGT
GDDIVASEGGDDWLYGDDGNDTVSGGADNDHLFGGTGDDSLDGGTGNDTLDGGDGNDMLNGGTGNDVFTGGVGTDTIQFA
GLFSNYTITYNPGAHQYVLTDTTGATKTVSSTDFELFSFTDGVKSDDDVYAVAANPYGQPEHIIANDPAFVGVAGLGLIA
ALLFL

Specific function: One of the virulence factors of A.pleuropneumoniae, which has a strong hemolytic activity and is cytotoxic for alveolar macrophages and neutrophils [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 6 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR013550
- InterPro:   IPR018504
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF00353 HemolysinCabind; PF02382 RTX; PF08339 RTX_C [H]

EC number: NA

Molecular weight: Translated: 154579; Mature: 154448

Theoretical pI: Translated: 3.72; Mature: 3.72

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFITLSNPSYSYNASKGKTTVQFDICFASNEMAGSKITGAKIDLQYNTSLVTAYQITN
CCCEEEECCCCCEEECCCCCEEEEEEEEEECCCCCCCEECCEEEEEEECCEEEEEEEECC
PTFSFEGDFGTETASVWVAAFDQTANLTGSGATGQIAMLATSNDANPIIVNGKVLTVTLS
CEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEECCEEEEEEEE
VTGEVNADTFAITLQKTADGGNNSISNATTEYFLDGGTYVAPPTSLADVTVDLHVNSDTG
EECCCCCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCEECCCCCEEEEEEEEEECCCCC
TSNTDNLTNDDTPTVTVNLTGKSLSEGQTLQIIDTSNSNAVVGTYTITSTDATNGITTKD
CCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEEEEECCCCCCEEECC
VTLSTLTSGAHALKAQLNAGSTAGTPSATATTVTIDTTAPTSLADVPVDLKSSSDSGLST
EEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCHHCCCEEECCCCCCCCCC
DNITNATTPVITVNLTGKTLVAGDIVQVIDTSNGNAVVGSYTVTTGGTGSSLDITLTTPL
CCCCCCCCCEEEEEECCCEEEECCEEEEEECCCCCEEEEEEEEEECCCCCEEEEEEECCH
SLGAHALKAQLVDVAGNVGTASTNALTVTVDTTAPTAPTLALATDSGSSNSDGITNVGTV
HCCCHHHHEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCEECEEE
NVTGIETNATWQYSTNGGTNWSNGTGTSFTLAAATYAVDAIRVRQTDVAGNVSGEGKIAT
EEEEEECCCEEEEECCCCCCCCCCCCCEEEEEEEEEEEEEEEEEEECCCCCCCCCCEEEE
AVTIDSSAPVAPTLAFTDAGTSTTDGHTSNNTITVTGIESNATWQYSTNGGTNWSNGTGT
EEEECCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
SFTIVDGTYNANTIKVKQTDVAGNVSGEGSLAPAITVDTVRPTVTVTPVTTALSAQGTTT
EEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEEEEEEEEECCCCEE
ITMTMSEAVTGFAADDIKTSSKYSISNFSATSSTVYTATYTANEATTDVAKELKFETNWT
EEEEEHHHHCCEECCCCCCCCCEEECCCCCCCCEEEEEEEECCCCHHHHHHHEEEECCCC
DAAGNQPKFGPTVDITLNDAALKIGETATVTFTFSEVPTGFDSSDISVTNANGQLSGLAV
CCCCCCCCCCCEEEEEECCCEEEECCEEEEEEEECCCCCCCCCCCEEEECCCCCEEEEEE
KSGSNGLVYEATFTPTANVTSATNKITVGKDWTNAEGVAPTNDTTDSPNYAVDTFRPTAT
ECCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCEE
IVVADIALKAGETSLVTITFSEAVSGFDNADLTIQNGTLTNVASSDGGITWSATLTPTAD
EEEEEEEEECCCEEEEEEEEHHHHCCCCCCCEEEECCEEEEEECCCCCEEEEEEECCCCC
ISDTTNVITLANTGVNDVAGNAGTGTTDSNNYAIDTARPTATIVVADTALKAGETSAVTI
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEECEECCCCCEEEEE
TFSEAVTGFDNSDLTIANGTLTPVASSDGGITWTATLTPTTNLEDATNVITVNKAGVTDA
EEHHHCCCCCCCCEEEECCEEEEEECCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCC
AGNAGVSTTDSNNYTIDTQAPAAPTLSITDNGQSTSDNLTNNGTVTVSGLETGATWQYST
CCCCCCEECCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEC
NGGTNWTTGSGTSFTLGAGTYAANNIQVKQTDAAGNVGIVGQITSQVDVDKVAPTLKSVV
CCCCCEECCCCCEEEEECCCEEECEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHE
VNGTSVVITYNEALDATNKPATTDFTVSNNTVNNVAVDSTAKTVTLTLGTTVVSGADVTV
ECCCEEEEEEHHHCCCCCCCCCEEEEEECCCCCEEEECCCCEEEEEEECCEEECCCCEEE
SYADPTTVDDSNAIQDVAGNDAAKFTTTISGTKTTTKVEVPQSSTAVNNIPIGTNAAGNP
EECCCCCCCCCCCHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCE
VIQLDIPANVDVIAKEVTDTNATTLTDKLNDSLDALTTASTGQIDSIAVQTGIDNYVATL
EEEEECCCCCEEEEEEECCCCCEEEEHHHCCCHHHHEECCCCCCEEEEEECCCCCEEEEE
STPDQANVVVRTLELKSANATTGAELVVTGNSAIGSNEALVIDTRGLQPGSVLNLENVEF
CCCCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCEEEECCCEE
AIIIGDNVTIRGGDGANIVYAGAGRQDIKLGDESDTLHGGTGDDIVASEGGDDWLYGDDG
EEEECCCEEEECCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCEEECCCCCCEEECCCC
NDTVSGGADNDHLFGGTGDDSLDGGTGNDTLDGGDGNDMLNGGTGNDVFTGGVGTDTIQF
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEE
AGLFSNYTITYNPGAHQYVLTDTTGATKTVSSTDFELFSFTDGVKSDDDVYAVAANPYGQ
EEEEECCEEEECCCCCEEEEEECCCCCEEECCCCEEEEEECCCCCCCCCEEEEEECCCCC
PEHIIANDPAFVGVAGLGLIAALLFL
CCEEEECCCCEEEHHHHHHHHHHHHC
>Mature Secondary Structure 
ADFITLSNPSYSYNASKGKTTVQFDICFASNEMAGSKITGAKIDLQYNTSLVTAYQITN
CCEEEECCCCCEEECCCCCEEEEEEEEEECCCCCCCEECCEEEEEEECCEEEEEEEECC
PTFSFEGDFGTETASVWVAAFDQTANLTGSGATGQIAMLATSNDANPIIVNGKVLTVTLS
CEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEECCEEEEEEEE
VTGEVNADTFAITLQKTADGGNNSISNATTEYFLDGGTYVAPPTSLADVTVDLHVNSDTG
EECCCCCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCEECCCCCEEEEEEEEEECCCCC
TSNTDNLTNDDTPTVTVNLTGKSLSEGQTLQIIDTSNSNAVVGTYTITSTDATNGITTKD
CCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEEEEECCCCCCEEECC
VTLSTLTSGAHALKAQLNAGSTAGTPSATATTVTIDTTAPTSLADVPVDLKSSSDSGLST
EEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCHHCCCEEECCCCCCCCCC
DNITNATTPVITVNLTGKTLVAGDIVQVIDTSNGNAVVGSYTVTTGGTGSSLDITLTTPL
CCCCCCCCCEEEEEECCCEEEECCEEEEEECCCCCEEEEEEEEEECCCCCEEEEEEECCH
SLGAHALKAQLVDVAGNVGTASTNALTVTVDTTAPTAPTLALATDSGSSNSDGITNVGTV
HCCCHHHHEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCEECEEE
NVTGIETNATWQYSTNGGTNWSNGTGTSFTLAAATYAVDAIRVRQTDVAGNVSGEGKIAT
EEEEEECCCEEEEECCCCCCCCCCCCCEEEEEEEEEEEEEEEEEEECCCCCCCCCCEEEE
AVTIDSSAPVAPTLAFTDAGTSTTDGHTSNNTITVTGIESNATWQYSTNGGTNWSNGTGT
EEEECCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
SFTIVDGTYNANTIKVKQTDVAGNVSGEGSLAPAITVDTVRPTVTVTPVTTALSAQGTTT
EEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEEEEEEEEECCCCEE
ITMTMSEAVTGFAADDIKTSSKYSISNFSATSSTVYTATYTANEATTDVAKELKFETNWT
EEEEEHHHHCCEECCCCCCCCCEEECCCCCCCCEEEEEEEECCCCHHHHHHHEEEECCCC
DAAGNQPKFGPTVDITLNDAALKIGETATVTFTFSEVPTGFDSSDISVTNANGQLSGLAV
CCCCCCCCCCCEEEEEECCCEEEECCEEEEEEEECCCCCCCCCCCEEEECCCCCEEEEEE
KSGSNGLVYEATFTPTANVTSATNKITVGKDWTNAEGVAPTNDTTDSPNYAVDTFRPTAT
ECCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCEE
IVVADIALKAGETSLVTITFSEAVSGFDNADLTIQNGTLTNVASSDGGITWSATLTPTAD
EEEEEEEEECCCEEEEEEEEHHHHCCCCCCCEEEECCEEEEEECCCCCEEEEEEECCCCC
ISDTTNVITLANTGVNDVAGNAGTGTTDSNNYAIDTARPTATIVVADTALKAGETSAVTI
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEECEECCCCCEEEEE
TFSEAVTGFDNSDLTIANGTLTPVASSDGGITWTATLTPTTNLEDATNVITVNKAGVTDA
EEHHHCCCCCCCCEEEECCEEEEEECCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCC
AGNAGVSTTDSNNYTIDTQAPAAPTLSITDNGQSTSDNLTNNGTVTVSGLETGATWQYST
CCCCCCEECCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEC
NGGTNWTTGSGTSFTLGAGTYAANNIQVKQTDAAGNVGIVGQITSQVDVDKVAPTLKSVV
CCCCCEECCCCCEEEEECCCEEECEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHE
VNGTSVVITYNEALDATNKPATTDFTVSNNTVNNVAVDSTAKTVTLTLGTTVVSGADVTV
ECCCEEEEEEHHHCCCCCCCCCEEEEEECCCCCEEEECCCCEEEEEEECCEEECCCCEEE
SYADPTTVDDSNAIQDVAGNDAAKFTTTISGTKTTTKVEVPQSSTAVNNIPIGTNAAGNP
EECCCCCCCCCCCHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCE
VIQLDIPANVDVIAKEVTDTNATTLTDKLNDSLDALTTASTGQIDSIAVQTGIDNYVATL
EEEEECCCCCEEEEEEECCCCCEEEEHHHCCCHHHHEECCCCCCEEEEEECCCCCEEEEE
STPDQANVVVRTLELKSANATTGAELVVTGNSAIGSNEALVIDTRGLQPGSVLNLENVEF
CCCCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCEEEECCCEE
AIIIGDNVTIRGGDGANIVYAGAGRQDIKLGDESDTLHGGTGDDIVASEGGDDWLYGDDG
EEEECCCEEEECCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCEEECCCCCCEEECCCC
NDTVSGGADNDHLFGGTGDDSLDGGTGNDTLDGGDGNDMLNGGTGNDVFTGGVGTDTIQF
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEE
AGLFSNYTITYNPGAHQYVLTDTTGATKTVSSTDFELFSFTDGVKSDDDVYAVAANPYGQ
EEEEECCEEEECCCCCEEEEEECCCCCEEECCCCEEEEEECCCCCCCCCEEEEEECCCCC
PEHIIANDPAFVGVAGLGLIAALLFL
CCEEEECCCCEEEHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1879928; 8181764; 8359891 [H]