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The map label for this gene is 78189758

Identifier: 78189758

GI number: 78189758

Start: 2324131

End: 2324742

Strand: Reverse

Name: 78189758

Synonym: Cag_1802

Alternate gene names: NA

Gene position: 2324742-2324131 (Counterclockwise)

Preceding gene: 78189762

Following gene: 78189757

Centisome position: 90.38

GC content: 49.18

Gene sequence:

>612_bases
ATGGAACCTTTGCCGAAGCAATTCTACCAATGCTCAACAATTGAGCTTACTGAAAAGCTGTTGGGTAAGTGTTTTGTGCG
CATTTTGCCCAATGGTACTCGTTTAGCGGGTCGAATTGTGGAGACGGAGGCGTATCTTGGTGAGGGCGACGAAGCGTGCC
ATGCGTGGCGTTCGCGCACTCCTCGTAATGAAATTATGTTCCGAGAAGCGGGGACGCTCTATGTTTATTTTACCTATGGC
GCGCATTATATGCTAAACATTGTCAGTGAGCCTGAAGAGCGTGCCGGAGCAGTGCTTATTCGTGCAATGGAGCCACTTGA
AGGTATTGAATTTATGCAGCAGCAGCGCAACACCACGAAGTTTCCCAATTTAATGAGTGGGCCAGGTAAGCTGACACAAG
CATTAGCTATTGAGCGGAGTTGTAATGGGCGAACTCTTTTTGATGGGGAATTTTTTGTAGCCGATGCTCCCGCCATTCCA
AGCCATCAGATTGGCACAAGCGGACGAATTGGTATTTCACGCAGCACGGAACTGCCATGGCGCAAATTTATTATGGGGAA
TGCGCATGTGTCGGGCGGAAAGGTGGGAGGGGTCGTGTCAAGCTTACAATGA

Upstream 100 bases:

>100_bases
CAAAAGCTTTTCGACAATTTTTAGCGATGCCGTATGTTACATTGGTTTGTACATTAGGTTAATATATAATACTTGCCAAT
ACAAATTTTAATCCCTTTGC

Downstream 100 bases:

>100_bases
TGATACAACTTTGCAAACGAGTTTGAGAGCATTACTTCATAGCTCTTTTGCTTTGGAAAGTTGGAAAAAAAATCTCTCTT
TAGGGCACTTCTCGGCATTA

Product: methylpurine-DNA glycosylase (MPG)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MEPLPKQFYQCSTIELTEKLLGKCFVRILPNGTRLAGRIVETEAYLGEGDEACHAWRSRTPRNEIMFREAGTLYVYFTYG
AHYMLNIVSEPEERAGAVLIRAMEPLEGIEFMQQQRNTTKFPNLMSGPGKLTQALAIERSCNGRTLFDGEFFVADAPAIP
SHQIGTSGRIGISRSTELPWRKFIMGNAHVSGGKVGGVVSSLQ

Sequences:

>Translated_203_residues
MEPLPKQFYQCSTIELTEKLLGKCFVRILPNGTRLAGRIVETEAYLGEGDEACHAWRSRTPRNEIMFREAGTLYVYFTYG
AHYMLNIVSEPEERAGAVLIRAMEPLEGIEFMQQQRNTTKFPNLMSGPGKLTQALAIERSCNGRTLFDGEFFVADAPAIP
SHQIGTSGRIGISRSTELPWRKFIMGNAHVSGGKVGGVVSSLQ
>Mature_203_residues
MEPLPKQFYQCSTIELTEKLLGKCFVRILPNGTRLAGRIVETEAYLGEGDEACHAWRSRTPRNEIMFREAGTLYVYFTYG
AHYMLNIVSEPEERAGAVLIRAMEPLEGIEFMQQQRNTTKFPNLMSGPGKLTQALAIERSCNGRTLFDGEFFVADAPAIP
SHQIGTSGRIGISRSTELPWRKFIMGNAHVSGGKVGGVVSSLQ

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=166, Percent_Identity=46.9879518072289, Blast_Score=128, Evalue=3e-30,
Organism=Homo sapiens, GI62632771, Length=166, Percent_Identity=46.9879518072289, Blast_Score=128, Evalue=3e-30,
Organism=Homo sapiens, GI62632765, Length=166, Percent_Identity=46.9879518072289, Blast_Score=128, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_CHLCH (Q3APM2)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_380096.1
- ProteinModelPortal:   Q3APM2
- SMR:   Q3APM2
- STRING:   Q3APM2
- GeneID:   3746917
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_1802
- eggNOG:   COG2094
- HOGENOM:   HBG664239
- OMA:   LCSGPGK
- ProtClustDB:   CLSK637971
- BioCyc:   CCHL340177:CAG_1802-MONOMER
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 22532; Mature: 22532

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPLPKQFYQCSTIELTEKLLGKCFVRILPNGTRLAGRIVETEAYLGEGDEACHAWRSRT
CCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEEEHHHHCCCCHHHHHHHHCCC
PRNEIMFREAGTLYVYFTYGAHYMLNIVSEPEERAGAVLIRAMEPLEGIEFMQQQRNTTK
CCHHEEEEECCEEEEEEECCCEEEEEECCCCCHHHCEEEEEHHCCHHHHHHHHHHCCCCC
FPNLMSGPGKLTQALAIERSCNGRTLFDGEFFVADAPAIPSHQIGTSGRIGISRSTELPW
CCCCCCCCHHHHHHHHHHCCCCCCEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCH
RKFIMGNAHVSGGKVGGVVSSLQ
HHHHCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MEPLPKQFYQCSTIELTEKLLGKCFVRILPNGTRLAGRIVETEAYLGEGDEACHAWRSRT
CCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEEEHHHHCCCCHHHHHHHHCCC
PRNEIMFREAGTLYVYFTYGAHYMLNIVSEPEERAGAVLIRAMEPLEGIEFMQQQRNTTK
CCHHEEEEECCEEEEEEECCCEEEEEECCCCCHHHCEEEEEHHCCHHHHHHHHHHCCCCC
FPNLMSGPGKLTQALAIERSCNGRTLFDGEFFVADAPAIPSHQIGTSGRIGISRSTELPW
CCCCCCCCHHHHHHHHHHCCCCCCEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCH
RKFIMGNAHVSGGKVGGVVSSLQ
HHHHCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA