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The map label for this gene is comM [H]

Identifier: 78189713

GI number: 78189713

Start: 2273996

End: 2275552

Strand: Reverse

Name: comM [H]

Synonym: Cag_1757

Alternate gene names: 78189713

Gene position: 2275552-2273996 (Counterclockwise)

Preceding gene: 78189715

Following gene: 78189709

Centisome position: 88.47

GC content: 46.89

Gene sequence:

>1557_bases
ATGCTTTCAATCCTCAATGCTGCGGCTTTAACGGGTATTGATGCCTTAAAAGTTACCGTTGAAATTAACGTTACTTCAGG
CTTGCCTGCCTTTACTGTAGTTGGTTTACCCGATAATGCTATCCGTGAAAGCCGCGAACGGGTTATGACGGCACTGCGAA
ATTCAGGTTTTCCAATTCCCCCTAAAAAAATAACGGTAAATCTTGCGCCTGCCGACATTAAAAAAGAGGGTACAGCTTTT
GACCTTCCCGTTGCTATTGGCTTGCTTGGTTCATTGGAGCTGCTTAACACCCATTTGCAGGATACCATGATTATGGGCGA
GTTAGCGTTAGATGGTTCGCTGCGGCGCATTAGCGGAGCGTTGCCCGTAGCAATTATGGCAGGCAAAGAGAAAATTCGCC
GTTTAATTGTGCCACAAACCAATGCGGCTGAAGCTGCCGTAGCCGTATCGGCAGCACAATCAGGAATTGAGGTGTATGGT
GTAGAGAGCTTAAATCAAACCGTTGCGCTATTGAACGGCACCTTTAGCATGAATCCTGTAACAGTAGATGTGGCTTCGCT
TTTTGAGGGCGAACAAGAGTATCCTGTTGATTTTTCAGATATTAAAGGGCAAACGGCAGCTAAAAAAGCTTTGGAGATTG
CAGCGGCTGGTGGACACAATGTTATTATGATTGGACCTCCCGGTAGTGGTAAAACCATGCTTGCAAAAGGGTTGCCCGGC
ATTTTACCCCCATTAGGATTTGAAGAGTCGTTAGAAACCACCAAAATTTATTCGGTTGCCAGCTTGCTTGAAAAAGATCG
CCCACTGATGGTGCGTCGCCCTTTTAGAAGCCCTCACCACACCACAAGTAACGTGGCGCTTATTGGCGGTGGAGCAATGG
CAAAACCCGGTGAAGTAAGCCTTGCTCACAATGGTATTTTATTTTTGGATGAGTTACCAGAATTTAGTCGCACAGCGCTT
GAAGTACTTCGCCAACCACTTGAAGAGCGTGAAGTAACGGTGGCGCGTATTGCGGTAACCACCAAATATCCTGCTGGGTT
TATGCTTATTGCCGCCATGAACCCAAGCCCTGCTGGTGCCTTAAAAGATCGCGATGGTAACTTTACCGCGCCGCCGCAAC
AAATTCAGCGCTACCTCTCAAAAATTTCAGGACCACTGCTTGACCGCATTGATATTCATATTGATGTGCCCAAAGTTGAA
AATGCTGAACTTTTTACTACAACCGCTGCTGAACCATCCGCCACAATTCGCCAGCGCGTTATTGCAGCACGCGCTATTCA
GCTTGAACGCTTTGCCAACACAAGTGCCCCGCGTATTTTTACCAACGCACAAATGAGTACGCGCCAAATTAAAAGCTATT
GCCAACTTGATAAGGAGTGTTCACAAAAGCTTATGAACGCCATGAACCGCATGAATCTTTCAGCACGCGCACACGACCGC
ATTTTAAAGGTGAGCCGCACCATTGCCGACCTCGACAAATCGGAGCACATTGCGTTACCCCACCTCATTCAAGCAATTCA
ATACCGCAACCTTGATCGTGATTTTTGGAGTTTTTAA

Upstream 100 bases:

>100_bases
AAAGATTATTATAATCTAACTCTATTTTTTTATCTTAAAAACACATTTTCCCATAAAAAAAGTAAAAGTAGCTTTTTAAA
TACCAAACTATCGGCATCTT

Downstream 100 bases:

>100_bases
AGAAGGGCGAGAAGGAAAATGGTTGGTAGCTTGCGCACTTACGATAACTTTGCAACAATTGGCTGCACCAACTCTTTATA
ACGCTTGTAAGAGAGAATCA

Product: Mg chelatase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MLSILNAAALTGIDALKVTVEINVTSGLPAFTVVGLPDNAIRESRERVMTALRNSGFPIPPKKITVNLAPADIKKEGTAF
DLPVAIGLLGSLELLNTHLQDTMIMGELALDGSLRRISGALPVAIMAGKEKIRRLIVPQTNAAEAAVAVSAAQSGIEVYG
VESLNQTVALLNGTFSMNPVTVDVASLFEGEQEYPVDFSDIKGQTAAKKALEIAAAGGHNVIMIGPPGSGKTMLAKGLPG
ILPPLGFEESLETTKIYSVASLLEKDRPLMVRRPFRSPHHTTSNVALIGGGAMAKPGEVSLAHNGILFLDELPEFSRTAL
EVLRQPLEEREVTVARIAVTTKYPAGFMLIAAMNPSPAGALKDRDGNFTAPPQQIQRYLSKISGPLLDRIDIHIDVPKVE
NAELFTTTAAEPSATIRQRVIAARAIQLERFANTSAPRIFTNAQMSTRQIKSYCQLDKECSQKLMNAMNRMNLSARAHDR
ILKVSRTIADLDKSEHIALPHLIQAIQYRNLDRDFWSF

Sequences:

>Translated_518_residues
MLSILNAAALTGIDALKVTVEINVTSGLPAFTVVGLPDNAIRESRERVMTALRNSGFPIPPKKITVNLAPADIKKEGTAF
DLPVAIGLLGSLELLNTHLQDTMIMGELALDGSLRRISGALPVAIMAGKEKIRRLIVPQTNAAEAAVAVSAAQSGIEVYG
VESLNQTVALLNGTFSMNPVTVDVASLFEGEQEYPVDFSDIKGQTAAKKALEIAAAGGHNVIMIGPPGSGKTMLAKGLPG
ILPPLGFEESLETTKIYSVASLLEKDRPLMVRRPFRSPHHTTSNVALIGGGAMAKPGEVSLAHNGILFLDELPEFSRTAL
EVLRQPLEEREVTVARIAVTTKYPAGFMLIAAMNPSPAGALKDRDGNFTAPPQQIQRYLSKISGPLLDRIDIHIDVPKVE
NAELFTTTAAEPSATIRQRVIAARAIQLERFANTSAPRIFTNAQMSTRQIKSYCQLDKECSQKLMNAMNRMNLSARAHDR
ILKVSRTIADLDKSEHIALPHLIQAIQYRNLDRDFWSF
>Mature_518_residues
MLSILNAAALTGIDALKVTVEINVTSGLPAFTVVGLPDNAIRESRERVMTALRNSGFPIPPKKITVNLAPADIKKEGTAF
DLPVAIGLLGSLELLNTHLQDTMIMGELALDGSLRRISGALPVAIMAGKEKIRRLIVPQTNAAEAAVAVSAAQSGIEVYG
VESLNQTVALLNGTFSMNPVTVDVASLFEGEQEYPVDFSDIKGQTAAKKALEIAAAGGHNVIMIGPPGSGKTMLAKGLPG
ILPPLGFEESLETTKIYSVASLLEKDRPLMVRRPFRSPHHTTSNVALIGGGAMAKPGEVSLAHNGILFLDELPEFSRTAL
EVLRQPLEEREVTVARIAVTTKYPAGFMLIAAMNPSPAGALKDRDGNFTAPPQQIQRYLSKISGPLLDRIDIHIDVPKVE
NAELFTTTAAEPSATIRQRVIAARAIQLERFANTSAPRIFTNAQMSTRQIKSYCQLDKECSQKLMNAMNRMNLSARAHDR
ILKVSRTIADLDKSEHIALPHLIQAIQYRNLDRDFWSF

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=515, Percent_Identity=43.1067961165049, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 56016; Mature: 56016

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00676 SIGMA54_INTERACT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSILNAAALTGIDALKVTVEINVTSGLPAFTVVGLPDNAIRESRERVMTALRNSGFPIP
CCCHHHHHHHCCCEEEEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCC
PKKITVNLAPADIKKEGTAFDLPVAIGLLGSLELLNTHLQDTMIMGELALDGSLRRISGA
CCEEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
LPVAIMAGKEKIRRLIVPQTNAAEAAVAVSAAQSGIEVYGVESLNQTVALLNGTFSMNPV
CCEEEECCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEHHHHHEEEEEECCEECCCE
TVDVASLFEGEQEYPVDFSDIKGQTAAKKALEIAAAGGHNVIMIGPPGSGKTMLAKGLPG
EEEHHHHHCCCCCCCCCHHHCCCCHHHHHHHHEEECCCCEEEEECCCCCCCEEHCCCCCC
ILPPLGFEESLETTKIYSVASLLEKDRPLMVRRPFRSPHHTTSNVALIGGGAMAKPGEVS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCCEE
LAHNGILFLDELPEFSRTALEVLRQPLEEREVTVARIAVTTKYPAGFMLIAAMNPSPAGA
EECCCEEEECCCCHHHHHHHHHHHCCHHHHCEEEEEEEEEEECCCCEEEEEECCCCCCCC
LKDRDGNFTAPPQQIQRYLSKISGPLLDRIDIHIDVPKVENAELFTTTAAEPSATIRQRV
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHH
IAARAIQLERFANTSAPRIFTNAQMSTRQIKSYCQLDKECSQKLMNAMNRMNLSARAHDR
HHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILKVSRTIADLDKSEHIALPHLIQAIQYRNLDRDFWSF
HHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MLSILNAAALTGIDALKVTVEINVTSGLPAFTVVGLPDNAIRESRERVMTALRNSGFPIP
CCCHHHHHHHCCCEEEEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCC
PKKITVNLAPADIKKEGTAFDLPVAIGLLGSLELLNTHLQDTMIMGELALDGSLRRISGA
CCEEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
LPVAIMAGKEKIRRLIVPQTNAAEAAVAVSAAQSGIEVYGVESLNQTVALLNGTFSMNPV
CCEEEECCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEHHHHHEEEEEECCEECCCE
TVDVASLFEGEQEYPVDFSDIKGQTAAKKALEIAAAGGHNVIMIGPPGSGKTMLAKGLPG
EEEHHHHHCCCCCCCCCHHHCCCCHHHHHHHHEEECCCCEEEEECCCCCCCEEHCCCCCC
ILPPLGFEESLETTKIYSVASLLEKDRPLMVRRPFRSPHHTTSNVALIGGGAMAKPGEVS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCCEE
LAHNGILFLDELPEFSRTALEVLRQPLEEREVTVARIAVTTKYPAGFMLIAAMNPSPAGA
EECCCEEEECCCCHHHHHHHHHHHCCHHHHCEEEEEEEEEEECCCCEEEEEECCCCCCCC
LKDRDGNFTAPPQQIQRYLSKISGPLLDRIDIHIDVPKVENAELFTTTAAEPSATIRQRV
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHH
IAARAIQLERFANTSAPRIFTNAQMSTRQIKSYCQLDKECSQKLMNAMNRMNLSARAHDR
HHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILKVSRTIADLDKSEHIALPHLIQAIQYRNLDRDFWSF
HHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]