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The map label for this gene is yqeC [H]

Identifier: 78189626

GI number: 78189626

Start: 2167431

End: 2168330

Strand: Reverse

Name: yqeC [H]

Synonym: Cag_1669

Alternate gene names: 78189626

Gene position: 2168330-2167431 (Counterclockwise)

Preceding gene: 78189627

Following gene: 78189625

Centisome position: 84.3

GC content: 50.56

Gene sequence:

>900_bases
ATGAATATTGGATTTATTGGACTTGGCAAAATGGGCTTCAACATGGTGCTCCATTTGCTTGAAAATGCCCATTCATTAAC
GGTGTTTGATCTTTCTCGTGATGCAATGGAGGCGGCATGTCGGCATGGTGCAACGGCGGCGACATCGGTGGAAGATGTGG
CGATGCAGCTTTCAGCACCTCGTTTGATTTGGCTCATGTTGCCAGCGGGTAGTGTGGTTGATAGCACCATTGAGCGTTTA
TTGCCAAATCTAACGGCGGGTGATTGCATTATTGATGGTGGCAATTCGCATTTCCACGACACCATGCGCCGTGCGGCACA
GTTGCGCGAAAAAGGCATTGCGTTGCTTGATGTTGGTACCAGTGGTGGGCTTGACGGTGCGCGTAACGGTGCTTGCATGA
TGGTTGGCGGCGAACCATCAGCTTACGGAATGGCTGAGCCGCTTTTTCGTGCTTTGTGCGTTGAAAATGGTTACGCTTAC
ACGGGGGCTTCGGGCGCAGGGCACTATGCAAAAATGGTGCATAATGGCATTGAGTATGGCATGATGCAAGCAATTGGCGA
AGGCTTCCATTTGTTAGAAAGCAGTGAATTTAATTTTCACCTTCCTGATGTTGCTAAGGTGTGGGCGCATGGCTCCGTTA
TTCGGAGCTGGTTGATGGATTTAATGGTACAAGCTTTGGAAAAAGATCCCACGCTGAGCTACCTCTCAGGCGCTATTGCC
GATTCGGGTGAAGGGCGTTGGACGGTTGAAGCAGCTCTTGAACAAAACGTTGCCACGCCCGTTATTGCGGCGGCACTTTT
TGCACGCTATCGTTCCCGTAGCGAAGGCAACCTCTCCGACCGCACAGTAGCAGCCTTGCGCCATGAGTTTGGCGGACATG
GATTTAGTGAAAAAAAGTAA

Upstream 100 bases:

>100_bases
GCAATCGTGGGCAGCCGTAAATGGTGCTTTAATTGAACGGTATCGGCGGATGGTAAATCAAGCGCAACGCTAATCTGCAC
CTTAATCTATTTATCTCATT

Downstream 100 bases:

>100_bases
ACTTGATAACCACTTATTCTAACCCCATGCAACCTAAGCCCGATAACTGTACCATTGTCATTTTTGGAGCGAGCGGCGAC
CTTGCAGCCCGCAAACTTTT

Product: 6-phosphogluconate dehydrogenase-like protein

Products: D-ribulose 5-phosphate; CO2; NADPH

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNIGFIGLGKMGFNMVLHLLENAHSLTVFDLSRDAMEAACRHGATAATSVEDVAMQLSAPRLIWLMLPAGSVVDSTIERL
LPNLTAGDCIIDGGNSHFHDTMRRAAQLREKGIALLDVGTSGGLDGARNGACMMVGGEPSAYGMAEPLFRALCVENGYAY
TGASGAGHYAKMVHNGIEYGMMQAIGEGFHLLESSEFNFHLPDVAKVWAHGSVIRSWLMDLMVQALEKDPTLSYLSGAIA
DSGEGRWTVEAALEQNVATPVIAAALFARYRSRSEGNLSDRTVAALRHEFGGHGFSEKK

Sequences:

>Translated_299_residues
MNIGFIGLGKMGFNMVLHLLENAHSLTVFDLSRDAMEAACRHGATAATSVEDVAMQLSAPRLIWLMLPAGSVVDSTIERL
LPNLTAGDCIIDGGNSHFHDTMRRAAQLREKGIALLDVGTSGGLDGARNGACMMVGGEPSAYGMAEPLFRALCVENGYAY
TGASGAGHYAKMVHNGIEYGMMQAIGEGFHLLESSEFNFHLPDVAKVWAHGSVIRSWLMDLMVQALEKDPTLSYLSGAIA
DSGEGRWTVEAALEQNVATPVIAAALFARYRSRSEGNLSDRTVAALRHEFGGHGFSEKK
>Mature_299_residues
MNIGFIGLGKMGFNMVLHLLENAHSLTVFDLSRDAMEAACRHGATAATSVEDVAMQLSAPRLIWLMLPAGSVVDSTIERL
LPNLTAGDCIIDGGNSHFHDTMRRAAQLREKGIALLDVGTSGGLDGARNGACMMVGGEPSAYGMAEPLFRALCVENGYAY
TGASGAGHYAKMVHNGIEYGMMQAIGEGFHLLESSEFNFHLPDVAKVWAHGSVIRSWLMDLMVQALEKDPTLSYLSGAIA
DSGEGRWTVEAALEQNVATPVIAAALFARYRSRSEGNLSDRTVAALRHEFGGHGFSEKK

Specific function: May act as NAD-dependent 6-P-gluconate dehydrogenase [H]

COG id: COG1023

COG function: function code G; Predicted 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=312, Percent_Identity=33.974358974359, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI23308751, Length=176, Percent_Identity=28.9772727272727, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1788341, Length=303, Percent_Identity=36.3036303630363, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI145693186, Length=224, Percent_Identity=28.125, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786719, Length=193, Percent_Identity=30.0518134715026, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790315, Length=203, Percent_Identity=27.0935960591133, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17542558, Length=305, Percent_Identity=36.0655737704918, Blast_Score=168, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6321695, Length=284, Percent_Identity=35.2112676056338, Blast_Score=168, Evalue=8e-43,
Organism=Saccharomyces cerevisiae, GI6321977, Length=284, Percent_Identity=34.5070422535211, Blast_Score=152, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24639279, Length=282, Percent_Identity=37.2340425531915, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24655230, Length=192, Percent_Identity=28.125, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19922568, Length=192, Percent_Identity=28.125, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR004849
- InterPro:   IPR006114
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: 1.1.1.44

Molecular weight: Translated: 32017; Mature: 32017

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00895 3_HYDROXYISOBUT_DH ; PS00461 6PGD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGFIGLGKMGFNMVLHLLENAHSLTVFDLSRDAMEAACRHGATAATSVEDVAMQLSAP
CCCEEEEECHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCC
RLIWLMLPAGSVVDSTIERLLPNLTAGDCIIDGGNSHFHDTMRRAAQLREKGIALLDVGT
EEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCEEEEEECC
SGGLDGARNGACMMVGGEPSAYGMAEPLFRALCVENGYAYTGASGAGHYAKMVHNGIEYG
CCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHH
MMQAIGEGFHLLESSEFNFHLPDVAKVWAHGSVIRSWLMDLMVQALEKDPTLSYLSGAIA
HHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
DSGEGRWTVEAALEQNVATPVIAAALFARYRSRSEGNLSDRTVAALRHEFGGHGFSEKK
CCCCCCEEEHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNIGFIGLGKMGFNMVLHLLENAHSLTVFDLSRDAMEAACRHGATAATSVEDVAMQLSAP
CCCEEEEECHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCC
RLIWLMLPAGSVVDSTIERLLPNLTAGDCIIDGGNSHFHDTMRRAAQLREKGIALLDVGT
EEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCEEEEEECC
SGGLDGARNGACMMVGGEPSAYGMAEPLFRALCVENGYAYTGASGAGHYAKMVHNGIEYG
CCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHH
MMQAIGEGFHLLESSEFNFHLPDVAKVWAHGSVIRSWLMDLMVQALEKDPTLSYLSGAIA
HHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
DSGEGRWTVEAALEQNVATPVIAAALFARYRSRSEGNLSDRTVAALRHEFGGHGFSEKK
CCCCCCEEEHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.05 {6-phosphogluconate}} 0.01 {6-phosphogluconate}} [C]

Substrates: 6-phospho-D-gluconate; NADP+

Specific reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]