Click here to switch to the map view.

The map label for this gene is fabH

Identifier: 78189621

GI number: 78189621

Start: 2162543

End: 2163532

Strand: Reverse

Name: fabH

Synonym: Cag_1664

Alternate gene names: 78189621

Gene position: 2163532-2162543 (Counterclockwise)

Preceding gene: 78189622

Following gene: 78189620

Centisome position: 84.12

GC content: 45.15

Gene sequence:

>990_bases
ATGAAAGCTGCAATAACCGCTACCGCAAATTATCTCCCTCCCGATATTCTTAGCAACCACGATCTGGAACTCATGCTCGA
TACCAACGATGAGTGGATTCGTTCGAGAACAGGTATTGGTGAGCGCCGAATTCTTAAAGATCCCACAAAAGCAACCTCTT
ACATGTGTGGTGAAGTAGCTCGTCAATTGTTGGAAAAACGCCAACTTGCGGCTACCGATATTGAGCTTATTATTGTGGCT
ACCATTACGCCCGATATGCCTTTTCCTGCAACAGCCTGCTTGGTGCAAGATTTAATTGGGGCAAAAAATGCGTGGGCGTT
TGATTTAAATGCTGCGTGCTCAGGTTTTCTTTATGCGCTCAACACTGCTATTCGTTTTGTTGAGTCGGGAGCCCATAAAA
AAGTAATGGTGATTGGTGCCGATAAAATGTCATCCATTATTGATTATACCGATCGTGCAACGGCTATTTTATTTGGTGAT
GGTGCAGGTGGCGTTCTTGTGGAGCCAGCGGCTGACGATAGCTGCGGTGTGCTTGATGTTCGTCTTTATTCTGATGGTAC
AAACGGACGTGAGCGTTTGCTGATGACGGGTGGAGGTAGTCGTTATCCTGCAAGCCATGAAACGGTGGATAAAAAAATGC
ACTACATTTACCAAGATGGTCGGCAGGTCTTTAAAGCGGCTGTTACTGCAATGGCTGATGTTGCAACGGAAATTATGCAA
CGCAACAACCTTACGGCTGACGATGTTGCCTATTTAGTGCCGCATCAAGCCAATCAGCGCATTATTGATGCTATCGCTGA
GCGCATGGGGGTGGATCGTGCTAAAGTGGTTTCAAATGTAGGATATTATGGCAACACAACGGCAGGTACTATTCCTATCT
GTCTTGCTGAGCTTGATGCAAACAATAAACTGAAACATGGTGATAACCTTGTGTTAGTCAGTTTTGGAGCAGGTTATACA
TGGGGTGGCATTTACGTTAAATGGCAATAA

Upstream 100 bases:

>100_bases
AAAGACTATGGTAAACCATTGAGTGCCTACCGTTAAAAAAATTGCCACACCAAAGTACAAAACGAGATATTTCTGATTTA
ACAACATAGCACGCACACGC

Downstream 100 bases:

>100_bases
GCAACAAGCATGAAAGCATTTGTTTTTCCGGGACAAGGTTCCCAATACTGCGGCATGGGGCGCGATTTATTTGAGAGCTT
TCCAGAAGCACGCGCTTTAA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKAAITATANYLPPDILSNHDLELMLDTNDEWIRSRTGIGERRILKDPTKATSYMCGEVARQLLEKRQLAATDIELIIVA
TITPDMPFPATACLVQDLIGAKNAWAFDLNAACSGFLYALNTAIRFVESGAHKKVMVIGADKMSSIIDYTDRATAILFGD
GAGGVLVEPAADDSCGVLDVRLYSDGTNGRERLLMTGGGSRYPASHETVDKKMHYIYQDGRQVFKAAVTAMADVATEIMQ
RNNLTADDVAYLVPHQANQRIIDAIAERMGVDRAKVVSNVGYYGNTTAGTIPICLAELDANNKLKHGDNLVLVSFGAGYT
WGGIYVKWQ

Sequences:

>Translated_329_residues
MKAAITATANYLPPDILSNHDLELMLDTNDEWIRSRTGIGERRILKDPTKATSYMCGEVARQLLEKRQLAATDIELIIVA
TITPDMPFPATACLVQDLIGAKNAWAFDLNAACSGFLYALNTAIRFVESGAHKKVMVIGADKMSSIIDYTDRATAILFGD
GAGGVLVEPAADDSCGVLDVRLYSDGTNGRERLLMTGGGSRYPASHETVDKKMHYIYQDGRQVFKAAVTAMADVATEIMQ
RNNLTADDVAYLVPHQANQRIIDAIAERMGVDRAKVVSNVGYYGNTTAGTIPICLAELDANNKLKHGDNLVLVSFGAGYT
WGGIYVKWQ
>Mature_329_residues
MKAAITATANYLPPDILSNHDLELMLDTNDEWIRSRTGIGERRILKDPTKATSYMCGEVARQLLEKRQLAATDIELIIVA
TITPDMPFPATACLVQDLIGAKNAWAFDLNAACSGFLYALNTAIRFVESGAHKKVMVIGADKMSSIIDYTDRATAILFGD
GAGGVLVEPAADDSCGVLDVRLYSDGTNGRERLLMTGGGSRYPASHETVDKKMHYIYQDGRQVFKAAVTAMADVATEIMQ
RNNLTADDVAYLVPHQANQRIIDAIAERMGVDRAKVVSNVGYYGNTTAGTIPICLAELDANNKLKHGDNLVLVSFGAGYT
WGGIYVKWQ

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family

Homologues:

Organism=Escherichia coli, GI1787333, Length=328, Percent_Identity=39.3292682926829, Blast_Score=235, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABH_CHLCH (Q3AQ09)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_379959.1
- ProteinModelPortal:   Q3AQ09
- SMR:   Q3AQ09
- STRING:   Q3AQ09
- GeneID:   3747258
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_1664
- eggNOG:   COG0332
- HOGENOM:   HBG649927
- OMA:   YIVPHQA
- ProtClustDB:   PRK09352
- BioCyc:   CCHL340177:CAG_1664-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01815
- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038
- Gene3D:   G3DSA:3.40.47.10
- TIGRFAMs:   TIGR00747

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C; SSF53901 Thiolase-like

EC number: =2.3.1.41

Molecular weight: Translated: 35744; Mature: 35744

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: ACT_SITE 113-113 ACT_SITE 255-255 ACT_SITE 285-285

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAITATANYLPPDILSNHDLELMLDTNDEWIRSRTGIGERRILKDPTKATSYMCGEVA
CCEEEEECCCCCCCHHHCCCCEEEEECCCHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHH
RQLLEKRQLAATDIELIIVATITPDMPFPATACLVQDLIGAKNAWAFDLNAACSGFLYAL
HHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEECHHHHHHHHHHH
NTAIRFVESGAHKKVMVIGADKMSSIIDYTDRATAILFGDGAGGVLVEPAADDSCGVLDV
HHHHHHHHCCCCCEEEEEECHHHHHHHCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEE
RLYSDGTNGRERLLMTGGGSRYPASHETVDKKMHYIYQDGRQVFKAAVTAMADVATEIMQ
EEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNNLTADDVAYLVPHQANQRIIDAIAERMGVDRAKVVSNVGYYGNTTAGTIPICLAELDA
HCCCCHHHHEEECCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEEEEECC
NNKLKHGDNLVLVSFGAGYTWGGIYVKWQ
CCCCCCCCCEEEEEECCCCEECEEEEEEC
>Mature Secondary Structure
MKAAITATANYLPPDILSNHDLELMLDTNDEWIRSRTGIGERRILKDPTKATSYMCGEVA
CCEEEEECCCCCCCHHHCCCCEEEEECCCHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHH
RQLLEKRQLAATDIELIIVATITPDMPFPATACLVQDLIGAKNAWAFDLNAACSGFLYAL
HHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEECHHHHHHHHHHH
NTAIRFVESGAHKKVMVIGADKMSSIIDYTDRATAILFGDGAGGVLVEPAADDSCGVLDV
HHHHHHHHCCCCCEEEEEECHHHHHHHCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEE
RLYSDGTNGRERLLMTGGGSRYPASHETVDKKMHYIYQDGRQVFKAAVTAMADVATEIMQ
EEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNNLTADDVAYLVPHQANQRIIDAIAERMGVDRAKVVSNVGYYGNTTAGTIPICLAELDA
HCCCCHHHHEEECCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEEEEECC
NNKLKHGDNLVLVSFGAGYTWGGIYVKWQ
CCCCCCCCCEEEEEECCCCEECEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA