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The map label for this gene is clpB [H]

Identifier: 78189445

GI number: 78189445

Start: 1953672

End: 1956263

Strand: Reverse

Name: clpB [H]

Synonym: Cag_1484

Alternate gene names: 78189445

Gene position: 1956263-1953672 (Counterclockwise)

Preceding gene: 78189447

Following gene: 78189444

Centisome position: 76.06

GC content: 45.49

Gene sequence:

>2592_bases
ATGGAAGGAAATTTTTCCGATAGAGTGCAAGATGTTATTCGCATGAGCCGCGAAGAGGCTATTCGACTTGGGCATCATCA
TATTGGCGCTGAGCATTTGTTGCTTGGATTATTGCGCGAAGGCGAAGGTATTGGGGCTCAAATTTTAAAAAATTTACAGA
TTGATTTAGATAATCTCCGCCAACGAGTTGTGGAAAGTTCGCAGCCAAAAGTGTCGGAACCGCATTCGGGTAATATTGTG
CTCACCAAACAAGCCGAACGCATTTTAAAAATCACCTACCTCGAAGCAAAAATTTGCAAATCGCATATTATTGGTACTGA
GCATTTACTTCTTTCCATTCTTAAAAGCGATGACCCCATTGCCACGCGTGCTTTAGAGCAACAAGGCGTTAACTACGATG
CCGTGCGCGATGAGCTTGCCGATATTACAGGTATTCCTCGTCCACCCGAACCCGACGAGCCGCCTACGCCACGCGAGCGT
CCCGTGTTTACAAAGGCGCAAACCGAGCCACCGTCGCCGCCGCCATCACCAGCACAACCAGCGCGCAAGCCCGAAAAAGA
AAAATCCAAAACACCCGTACTCGATAACTTTGGGCGCGATCTCACCCATCTTGCAATTGAGGATAAACTTGATCCTATTA
TTGGGCGCGAAAAAGAGATTGAGCGCGTTGCTCAAGTGTTGAGCCGCCGCAAAAAAAATAATCCCGTGCTTATTGGTGAG
CCAGGTGTGGGTAAAACCGCTATTGCAGAAGGGTTAGCATTAAAAATAATTCAGCGCAAAGTATCGCGTGTGCTCTACAA
TAAGCGGGTTGTAGCGCTCGATATGGCAGCGTTAGTAGCAGGTACCAAATATCGTGGGCAGTTTGAAGAGCGTATGAAAG
CCTTAATGACGGAGCTTGAAAAAACGCGCGATGTTATTCTTTTTATTGATGAATTGCACACCATTGTTGGAGCTGGTGGC
GCTTCAGGTTCACTTGATGCGAGCAATATTTTTAAACCAGCCCTTGCGCGTGGTGAGTTGCAGTGCATTGGAGCCACAAC
ACTTGATGAGTATCGCCAATTTATTGAAAAAGATGGGGCGCTTGATCGTCGTTTTCAAAAAATTATGGTGGAACCAACAT
CGGCTGACGAAACCATTCAAATTCTTAACAACATTAAATCGAAGTACGAAGCTCACCATAGAGTTACCTACTCCGAATTT
GCTATCGAAAAAGCGGTACGACTCTCTGAGCGCTATATTACCGATCGCTTTTTGCCCGATAAAGCCATTGACGTTATGGA
TGAAGCTGGCGCACGAGTACACCTCAGCAACATTCACGTACCAGCCAATATTCTTGCGCTTGAAAAAGAGATTGAAGAGA
TCAAGAGTGAAAAAAATGATATGGTGCGCCTTCAAAATTTTGAAGAAGCCGCAAGTTTACGCGATCGCGAAAAAGCCGTT
AACGATCAATTGGAACAAGCCAAGCAAGAGTGGGAAGAGAATTCCGCCGATATTGTGTATGATGTAAGCGAAACCGACAT
TACCTCCGTTATTGCTATGATGACGGGTATTCCGGTTGCACGCGTTGCACAATCGGAATCGCAACGACTGCTTACTATGG
AAGCCGATTTAAAGCGCGAAGTTATTGGGCAAGAAGAAGCTATCACCAAAATTACCCGAGCTATTCAGCGCACACGCGCA
GGACTTAAAGACCCCATGCGTCCTATTGGCTCCTTTATTTTTCTTGGACCAACCGGCGTTGGTAAAACCGAGCTTGCCAA
AGCGCTCACTCGTTACATGTTCGACACCGAAGATGCGCTGATTCGTGCTGATATGAGCGAATACATGGAAAAATTTGCTG
TTAGCCGCCTTGTTGGAGCGCCTCCGGGCTACGTTGGCTACGAAGAAGGTGGTCAGCTTACCGAAAAAGTGCGCCGTAAA
CCATATTCCGTAGTGCTTATTGATGAAATTGAAAAAGCGCACCCCGATGTTTTCAACATTCTCTTGCAAGTGCTTGACGA
AGGTATTTTAACCGATGGTATGGGCAGAAAAGTGGATTTTCGCAACACCATTATTATTATGACCTCCAATATTGGGGCAC
GCGATATTCGCAACTTTAGCGCAGGAGCAGGCATGGGCTTTGCCCCCATTGACGATGGCACAGGCAATTATAAAGCCATG
AAATCCACCATTGAAGATGCCCTCAAGCGCGTCTTTAATCCCGAGTTCCTTAACCGTATTGACGACATTGTTGTTTTCCA
TCAATTAGAAAAACAACATATCTTTAAAATTATTGATATTACGGCAGGCAAGCTCTTTAAACGCCTTAACGATATGGGCA
TTACCGTCCAAATTGATGAAAAAGCAAAAGAGTTTTTAGTGGATAAAGGCTACGATCAAAAATATGGAGCTCGTCCATTA
AAACGCGCCTTGCAGAAATATGTAGAAGACCCACTTGCAGAAGAAATGCTTAAAGGCAACTTTGGAGAGGGAAGCACCAT
CCATATTGCTTTCAACGAAGGGAGCCAAGAGCTTAGCTTTAGTGATGGTGTAGCGACGGAAGAGAGTATTACGAGTAGCG
ATAGTGCCACTGCGGCTGAAGTACAAGAGTAG

Upstream 100 bases:

>100_bases
AGCAAATATTGTTGTGGGAACGCTTTACATAACTACCGCTTTAGTAAAGAGAAGAATTGGTGCTAAAGCAACACATTTAG
TTAAGATTTAAGGAGAAGCA

Downstream 100 bases:

>100_bases
AACGTTGTAACTCAAACCTCTATCGGGAACATGGTTTTGCAACTCTGTTCCCGATTTTTTTTAAAGCCAACAAAAAGTGT
TCATCTTTTTTTACAAATTA

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 863; Mature: 863

Protein sequence:

>863_residues
MEGNFSDRVQDVIRMSREEAIRLGHHHIGAEHLLLGLLREGEGIGAQILKNLQIDLDNLRQRVVESSQPKVSEPHSGNIV
LTKQAERILKITYLEAKICKSHIIGTEHLLLSILKSDDPIATRALEQQGVNYDAVRDELADITGIPRPPEPDEPPTPRER
PVFTKAQTEPPSPPPSPAQPARKPEKEKSKTPVLDNFGRDLTHLAIEDKLDPIIGREKEIERVAQVLSRRKKNNPVLIGE
PGVGKTAIAEGLALKIIQRKVSRVLYNKRVVALDMAALVAGTKYRGQFEERMKALMTELEKTRDVILFIDELHTIVGAGG
ASGSLDASNIFKPALARGELQCIGATTLDEYRQFIEKDGALDRRFQKIMVEPTSADETIQILNNIKSKYEAHHRVTYSEF
AIEKAVRLSERYITDRFLPDKAIDVMDEAGARVHLSNIHVPANILALEKEIEEIKSEKNDMVRLQNFEEAASLRDREKAV
NDQLEQAKQEWEENSADIVYDVSETDITSVIAMMTGIPVARVAQSESQRLLTMEADLKREVIGQEEAITKITRAIQRTRA
GLKDPMRPIGSFIFLGPTGVGKTELAKALTRYMFDTEDALIRADMSEYMEKFAVSRLVGAPPGYVGYEEGGQLTEKVRRK
PYSVVLIDEIEKAHPDVFNILLQVLDEGILTDGMGRKVDFRNTIIIMTSNIGARDIRNFSAGAGMGFAPIDDGTGNYKAM
KSTIEDALKRVFNPEFLNRIDDIVVFHQLEKQHIFKIIDITAGKLFKRLNDMGITVQIDEKAKEFLVDKGYDQKYGARPL
KRALQKYVEDPLAEEMLKGNFGEGSTIHIAFNEGSQELSFSDGVATEESITSSDSATAAEVQE

Sequences:

>Translated_863_residues
MEGNFSDRVQDVIRMSREEAIRLGHHHIGAEHLLLGLLREGEGIGAQILKNLQIDLDNLRQRVVESSQPKVSEPHSGNIV
LTKQAERILKITYLEAKICKSHIIGTEHLLLSILKSDDPIATRALEQQGVNYDAVRDELADITGIPRPPEPDEPPTPRER
PVFTKAQTEPPSPPPSPAQPARKPEKEKSKTPVLDNFGRDLTHLAIEDKLDPIIGREKEIERVAQVLSRRKKNNPVLIGE
PGVGKTAIAEGLALKIIQRKVSRVLYNKRVVALDMAALVAGTKYRGQFEERMKALMTELEKTRDVILFIDELHTIVGAGG
ASGSLDASNIFKPALARGELQCIGATTLDEYRQFIEKDGALDRRFQKIMVEPTSADETIQILNNIKSKYEAHHRVTYSEF
AIEKAVRLSERYITDRFLPDKAIDVMDEAGARVHLSNIHVPANILALEKEIEEIKSEKNDMVRLQNFEEAASLRDREKAV
NDQLEQAKQEWEENSADIVYDVSETDITSVIAMMTGIPVARVAQSESQRLLTMEADLKREVIGQEEAITKITRAIQRTRA
GLKDPMRPIGSFIFLGPTGVGKTELAKALTRYMFDTEDALIRADMSEYMEKFAVSRLVGAPPGYVGYEEGGQLTEKVRRK
PYSVVLIDEIEKAHPDVFNILLQVLDEGILTDGMGRKVDFRNTIIIMTSNIGARDIRNFSAGAGMGFAPIDDGTGNYKAM
KSTIEDALKRVFNPEFLNRIDDIVVFHQLEKQHIFKIIDITAGKLFKRLNDMGITVQIDEKAKEFLVDKGYDQKYGARPL
KRALQKYVEDPLAEEMLKGNFGEGSTIHIAFNEGSQELSFSDGVATEESITSSDSATAAEVQE
>Mature_863_residues
MEGNFSDRVQDVIRMSREEAIRLGHHHIGAEHLLLGLLREGEGIGAQILKNLQIDLDNLRQRVVESSQPKVSEPHSGNIV
LTKQAERILKITYLEAKICKSHIIGTEHLLLSILKSDDPIATRALEQQGVNYDAVRDELADITGIPRPPEPDEPPTPRER
PVFTKAQTEPPSPPPSPAQPARKPEKEKSKTPVLDNFGRDLTHLAIEDKLDPIIGREKEIERVAQVLSRRKKNNPVLIGE
PGVGKTAIAEGLALKIIQRKVSRVLYNKRVVALDMAALVAGTKYRGQFEERMKALMTELEKTRDVILFIDELHTIVGAGG
ASGSLDASNIFKPALARGELQCIGATTLDEYRQFIEKDGALDRRFQKIMVEPTSADETIQILNNIKSKYEAHHRVTYSEF
AIEKAVRLSERYITDRFLPDKAIDVMDEAGARVHLSNIHVPANILALEKEIEEIKSEKNDMVRLQNFEEAASLRDREKAV
NDQLEQAKQEWEENSADIVYDVSETDITSVIAMMTGIPVARVAQSESQRLLTMEADLKREVIGQEEAITKITRAIQRTRA
GLKDPMRPIGSFIFLGPTGVGKTELAKALTRYMFDTEDALIRADMSEYMEKFAVSRLVGAPPGYVGYEEGGQLTEKVRRK
PYSVVLIDEIEKAHPDVFNILLQVLDEGILTDGMGRKVDFRNTIIIMTSNIGARDIRNFSAGAGMGFAPIDDGTGNYKAM
KSTIEDALKRVFNPEFLNRIDDIVVFHQLEKQHIFKIIDITAGKLFKRLNDMGITVQIDEKAKEFLVDKGYDQKYGARPL
KRALQKYVEDPLAEEMLKGNFGEGSTIHIAFNEGSQELSFSDGVATEESITSSDSATAAEVQE

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=328, Percent_Identity=39.6341463414634, Blast_Score=206, Evalue=1e-52,
Organism=Escherichia coli, GI1788943, Length=702, Percent_Identity=50.1424501424501, Blast_Score=665, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=821, Percent_Identity=39.4640682095006, Blast_Score=546, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6320464, Length=719, Percent_Identity=46.3143254520167, Blast_Score=589, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6323002, Length=720, Percent_Identity=39.7222222222222, Blast_Score=498, Evalue=1e-141,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 96400; Mature: 96400

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGNFSDRVQDVIRMSREEAIRLGHHHIGAEHLLLGLLREGEGIGAQILKNLQIDLDNLR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHH
QRVVESSQPKVSEPHSGNIVLTKQAERILKITYLEAKICKSHIIGTEHLLLSILKSDDPI
HHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCH
ATRALEQQGVNYDAVRDELADITGIPRPPEPDEPPTPRERPVFTKAQTEPPSPPPSPAQP
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ARKPEKEKSKTPVLDNFGRDLTHLAIEDKLDPIIGREKEIERVAQVLSRRKKNNPVLIGE
CCCCCHHHCCCCCHHHHCCHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHCCCCCEEEEC
PGVGKTAIAEGLALKIIQRKVSRVLYNKRVVALDMAALVAGTKYRGQFEERMKALMTELE
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
KTRDVILFIDELHTIVGAGGASGSLDASNIFKPALARGELQCIGATTLDEYRQFIEKDGA
HHHHHEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCH
LDRRFQKIMVEPTSADETIQILNNIKSKYEAHHRVTYSEFAIEKAVRLSERYITDRFLPD
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCH
KAIDVMDEAGARVHLSNIHVPANILALEKEIEEIKSEKNDMVRLQNFEEAASLRDREKAV
HHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
NDQLEQAKQEWEENSADIVYDVSETDITSVIAMMTGIPVARVAQSESQRLLTMEADLKRE
HHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCEEEEHHHHHHHH
VIGQEEAITKITRAIQRTRAGLKDPMRPIGSFIFLGPTGVGKTELAKALTRYMFDTEDAL
HHCHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEECCCCCCHHHHHHHHHHHHHCCHHHH
IRADMSEYMEKFAVSRLVGAPPGYVGYEEGGQLTEKVRRKPYSVVLIDEIEKAHPDVFNI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECHHHHCCHHHHH
LLQVLDEGILTDGMGRKVDFRNTIIIMTSNIGARDIRNFSAGAGMGFAPIDDGTGNYKAM
HHHHHHCCHHCCCCCCEEECCCEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHH
KSTIEDALKRVFNPEFLNRIDDIVVFHQLEKQHIFKIIDITAGKLFKRLNDMGITVQIDE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECH
KAKEFLVDKGYDQKYGARPLKRALQKYVEDPLAEEMLKGNFGEGSTIHIAFNEGSQELSF
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
SDGVATEESITSSDSATAAEVQE
CCCCCCHHHCCCCCCCCHHHCCC
>Mature Secondary Structure
MEGNFSDRVQDVIRMSREEAIRLGHHHIGAEHLLLGLLREGEGIGAQILKNLQIDLDNLR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHH
QRVVESSQPKVSEPHSGNIVLTKQAERILKITYLEAKICKSHIIGTEHLLLSILKSDDPI
HHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCH
ATRALEQQGVNYDAVRDELADITGIPRPPEPDEPPTPRERPVFTKAQTEPPSPPPSPAQP
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ARKPEKEKSKTPVLDNFGRDLTHLAIEDKLDPIIGREKEIERVAQVLSRRKKNNPVLIGE
CCCCCHHHCCCCCHHHHCCHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHCCCCCEEEEC
PGVGKTAIAEGLALKIIQRKVSRVLYNKRVVALDMAALVAGTKYRGQFEERMKALMTELE
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
KTRDVILFIDELHTIVGAGGASGSLDASNIFKPALARGELQCIGATTLDEYRQFIEKDGA
HHHHHEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCH
LDRRFQKIMVEPTSADETIQILNNIKSKYEAHHRVTYSEFAIEKAVRLSERYITDRFLPD
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCH
KAIDVMDEAGARVHLSNIHVPANILALEKEIEEIKSEKNDMVRLQNFEEAASLRDREKAV
HHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
NDQLEQAKQEWEENSADIVYDVSETDITSVIAMMTGIPVARVAQSESQRLLTMEADLKRE
HHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCEEEEHHHHHHHH
VIGQEEAITKITRAIQRTRAGLKDPMRPIGSFIFLGPTGVGKTELAKALTRYMFDTEDAL
HHCHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEECCCCCCHHHHHHHHHHHHHCCHHHH
IRADMSEYMEKFAVSRLVGAPPGYVGYEEGGQLTEKVRRKPYSVVLIDEIEKAHPDVFNI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECHHHHCCHHHHH
LLQVLDEGILTDGMGRKVDFRNTIIIMTSNIGARDIRNFSAGAGMGFAPIDDGTGNYKAM
HHHHHHCCHHCCCCCCEEECCCEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHH
KSTIEDALKRVFNPEFLNRIDDIVVFHQLEKQHIFKIIDITAGKLFKRLNDMGITVQIDE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECH
KAKEFLVDKGYDQKYGARPLKRALQKYVEDPLAEEMLKGNFGEGSTIHIAFNEGSQELSF
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
SDGVATEESITSSDSATAAEVQE
CCCCCCHHHCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]