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The map label for this gene is argK [C]

Identifier: 78189203

GI number: 78189203

Start: 1643795

End: 1644805

Strand: Reverse

Name: argK [C]

Synonym: Cag_1237

Alternate gene names: 78189203

Gene position: 1644805-1643795 (Counterclockwise)

Preceding gene: 78189204

Following gene: 78189197

Centisome position: 63.95

GC content: 51.63

Gene sequence:

>1011_bases
ATGCCGCACCACCATACATTTGATGTAGAAGCCATAGCCAATGCCATTATGCAAGGCAATCGCCACCAGCTTAGTCGAGC
AATTACGTTGGTGGAGTCGCAACGCATAGAGCACCACCATGTAGCTGAAGCTATTCTTGAGCGTTGTATGGCAAGCAATC
GCCATGCGCTACGTATTGGTATTACGGGTTCGCCCGGTGCGGGCAAAAGCACCTTTATTGAGGCTTTTGGCGAACATATT
CTTTCGCAAGGATTAAGGCTTGCGGTGCTGGCAATTGACCCAAGTAGCCACCATTCCAAAGGAAGTATTCTTGGCGATAA
AGCACGAATGGAAAAGCTTTCGGGACGAAAAGAGGCGTTTATTCGTCCAACGCCTTCATCGGGGCATCTTGGCGGCACTT
CACCCCGAACGCACGAGGCGCTATTGCTGTGCGAGGCGGCTGGTTATGACGTAATAATTGTGGAGACGGTGGGTGTTGGG
CAGTCGGAGCTGCACATTGAGCAGATGGTAGATTTTGTGCTGCTTTTAATGCTGCCCGGTTCGGGCGATGAGCTGCAAGG
CATTAAGCGAGGAATTATGGAAATTGCCGATATGATTGCCATCACCAAATGCGATGGTTTGCAAGCCACCAGCGCGGCTA
TTTCTCATGCAGAATTTGAAGCGGCGCTGCGCATGGTGCCAAAGCGCCACCCCTTTTGGCAGCCAAGCGTGCAACTTACC
TCGGCGGTTACGGGTGTGGGCATTGCTGAGGTGTGGCAGCAAATTGAACGTTTTTTTGCTATCATGCAGCAAGAGAATAG
TTTAGAGACTCAGCGGCGTGAGCAACGGCGCCATTTGTTGGCAAATGTGCTGGAAGAGCAACTCCGCCGCCTCTTTTTTA
ACCACCCCACAATTCGTCAGCAGCAACCCCATCTTGTGCAGCAAGTGCTTGATGGCACGCTTAGCCCATTTACCGCCGCC
ACACGCCTTATTGAGCTGTTTCGCCACAATCCAATAGGAGAGAAACAGTAG

Upstream 100 bases:

>100_bases
AATAAAGCGTCGGAATAAATGGTGCCTCATAGCATATTAAAATTCTGTACATTTCTTTATATAGCAATCATTACAAAACC
AACGTTCCTCCCGCCTTATT

Downstream 100 bases:

>100_bases
AAAAGTACTCTTTAGAAATAAGAACGGAAACCAATGCCCAACGTTGCAACGTTAATATCGTCATAACATTGCGAAGTACT
GTTGCTTTCGCCCGGTAAAG

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MPHHHTFDVEAIANAIMQGNRHQLSRAITLVESQRIEHHHVAEAILERCMASNRHALRIGITGSPGAGKSTFIEAFGEHI
LSQGLRLAVLAIDPSSHHSKGSILGDKARMEKLSGRKEAFIRPTPSSGHLGGTSPRTHEALLLCEAAGYDVIIVETVGVG
QSELHIEQMVDFVLLLMLPGSGDELQGIKRGIMEIADMIAITKCDGLQATSAAISHAEFEAALRMVPKRHPFWQPSVQLT
SAVTGVGIAEVWQQIERFFAIMQQENSLETQRREQRRHLLANVLEEQLRRLFFNHPTIRQQQPHLVQQVLDGTLSPFTAA
TRLIELFRHNPIGEKQ

Sequences:

>Translated_336_residues
MPHHHTFDVEAIANAIMQGNRHQLSRAITLVESQRIEHHHVAEAILERCMASNRHALRIGITGSPGAGKSTFIEAFGEHI
LSQGLRLAVLAIDPSSHHSKGSILGDKARMEKLSGRKEAFIRPTPSSGHLGGTSPRTHEALLLCEAAGYDVIIVETVGVG
QSELHIEQMVDFVLLLMLPGSGDELQGIKRGIMEIADMIAITKCDGLQATSAAISHAEFEAALRMVPKRHPFWQPSVQLT
SAVTGVGIAEVWQQIERFFAIMQQENSLETQRREQRRHLLANVLEEQLRRLFFNHPTIRQQQPHLVQQVLDGTLSPFTAA
TRLIELFRHNPIGEKQ
>Mature_335_residues
PHHHTFDVEAIANAIMQGNRHQLSRAITLVESQRIEHHHVAEAILERCMASNRHALRIGITGSPGAGKSTFIEAFGEHIL
SQGLRLAVLAIDPSSHHSKGSILGDKARMEKLSGRKEAFIRPTPSSGHLGGTSPRTHEALLLCEAAGYDVIIVETVGVGQ
SELHIEQMVDFVLLLMLPGSGDELQGIKRGIMEIADMIAITKCDGLQATSAAISHAEFEAALRMVPKRHPFWQPSVQLTS
AVTGVGIAEVWQQIERFFAIMQQENSLETQRREQRRHLLANVLEEQLRRLFFNHPTIRQQQPHLVQQVLDGTLSPFTAAT
RLIELFRHNPIGEKQ

Specific function: Probable GTPase. May also bind and hydrolyze ATP. May function as chaperone (Probable) [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=330, Percent_Identity=45.4545454545455, Blast_Score=295, Evalue=5e-80,
Organism=Escherichia coli, GI1789285, Length=312, Percent_Identity=46.7948717948718, Blast_Score=271, Evalue=6e-74,
Organism=Caenorhabditis elegans, GI71994271, Length=336, Percent_Identity=38.3928571428571, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71994275, Length=272, Percent_Identity=41.5441176470588, Blast_Score=237, Evalue=7e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 37312; Mature: 37181

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHHHTFDVEAIANAIMQGNRHQLSRAITLVESQRIEHHHVAEAILERCMASNRHALRIG
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
ITGSPGAGKSTFIEAFGEHILSQGLRLAVLAIDPSSHHSKGSILGDKARMEKLSGRKEAF
ECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCEE
IRPTPSSGHLGGTSPRTHEALLLCEAAGYDVIIVETVGVGQSELHIEQMVDFVLLLMLPG
ECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
SGDELQGIKRGIMEIADMIAITKCDGLQATSAAISHAEFEAALRMVPKRHPFWQPSVQLT
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
SAVTGVGIAEVWQQIERFFAIMQQENSLETQRREQRRHLLANVLEEQLRRLFFNHPTIRQ
HHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QQPHLVQQVLDGTLSPFTAATRLIELFRHNPIGEKQ
CCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PHHHTFDVEAIANAIMQGNRHQLSRAITLVESQRIEHHHVAEAILERCMASNRHALRIG
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
ITGSPGAGKSTFIEAFGEHILSQGLRLAVLAIDPSSHHSKGSILGDKARMEKLSGRKEAF
ECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCEE
IRPTPSSGHLGGTSPRTHEALLLCEAAGYDVIIVETVGVGQSELHIEQMVDFVLLLMLPG
ECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
SGDELQGIKRGIMEIADMIAITKCDGLQATSAAISHAEFEAALRMVPKRHPFWQPSVQLT
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
SAVTGVGIAEVWQQIERFFAIMQQENSLETQRREQRRHLLANVLEEQLRRLFFNHPTIRQ
HHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QQPHLVQQVLDGTLSPFTAATRLIELFRHNPIGEKQ
CCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]