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The map label for this gene is rsmB [H]

Identifier: 78189086

GI number: 78189086

Start: 1509145

End: 1510434

Strand: Reverse

Name: rsmB [H]

Synonym: Cag_1119

Alternate gene names: 78189086

Gene position: 1510434-1509145 (Counterclockwise)

Preceding gene: 78189095

Following gene: 78189085

Centisome position: 58.72

GC content: 49.46

Gene sequence:

>1290_bases
ATGTCAACTGCACGAGAAGTAGCGCTGCAAGTGCTGCAAGCGTTAGAAAAAAGTAGCGAGCGCTCCGATGCGTTGTTGCA
CAAACATCTTGAAGCGTCGGGATTGGAGCGCGTTGAGCGGGCACTTGCCACCGAGTTGGTGAATGGCGTGTTGCGTTGGC
AGCTTCAGCTTGATAGCCGCATTAGCCTTGCTTACCATCACAAGCTTGAGGCAGCGGCTCCTGTATTGCGCAATATTTTA
CGATTAGGCGCCTATCAGCTTCTTTTTTTAACCAAAATTCCTCGTTGGGCGGCGGTAAACGAGTGTGTAAAACTTGCTCG
AAAGTATAAGGGTGAGCGAATGGCAAAGTTGGTTAATGGTGTGTTGCGCCATCTTGATGGTGGCAATGAGGCGTTTGAAA
AGCTGTTGCAAGGGCGTTCACAAGCCGAGCAACTTGCACTCCAATTTTCGCATCCCGCATGGTTAATTGAGCGTTGGCTT
GCTACGTATGGCGAGCTGAAAACCCGACAATTGTTGCATTACAACAATCAAGCGCCAATGATGGGTTTTCGCATTAATCG
GTTGAAAGCTGATGCAAAGGATTTTTTTGATAATCCTACCTTTGCGGCGGCAATGGAGCCGTGCGAATTGCCTTATTGTT
TTCTTTCGCGAGAATTTTCGCTTTTTGAGACGGCGTTGCAAGAGGGCGTTTTAAGTGTGCAAAATCCCACGCAAGCGTTG
GCGCCGTTGTTGCTTAATCCAGCCCCACAGAGTGTGGTGATTGACCTTTGTGCGGCACCGGGCGGTAAAGCAATGTTTAT
GGCGGAATTAATGCACAATCAAGGGGAGGTGATTGCTGTTGATCAGTATGAGCAAAAGTTACGGAAGCTTGAAAGCCATG
CGCAGGCGTTGGGGCTTACTATTATTCGCACGGTAGCTGGCGATGCTCGGAGTGTTGCGCCAAATCTGCAAGCTGATGCG
GTGTTGCTTGATGCTCCTTGTTCGGGCACGGGCGTTATTGGGCGTCGTGCTGAGTTACGCTGGAAGGTAACGCCTGCAAT
GGTTGCGGAATTGCAAGGGTTGCAAGCTGAATTATTGGATCATGCGGCTACGTTGCTTAAGCCTCAAGGTAGGTTAGTGT
ATGCTACTTGTTCTATTGAGCCTGAAGAGAATGGTGAGCAAGTTGCAGCTTTTTTGCAACGTCATCCTAATTTTGTTGCC
GAACCTCATGCCCAGCACATGACGTTGCCGGGCGATCGTTATGGCTACGATGGCGGGTTTTGCCAATGCCTCCGTAAACT
GCAAGAATAA

Upstream 100 bases:

>100_bases
TAATTTTCTGCAATTGTTTGGAGCGGTGAGGATTACTTGTATTGGGGTGAGCTTATTCTATATTATTTAAATATACTTAA
AAATTCTGATAATTACCTTT

Downstream 100 bases:

>100_bases
ACCGTATGTCCACACTGAGCAGTAGCTACCAAACCACACTCAACAGCTTTCTTAACTACCTTATTGTTGAGCGCAACTTT
TCCGCCAACACACGCTCATC

Product: Fmu, rRNA SAM-dependent methyltransferase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSTAREVALQVLQALEKSSERSDALLHKHLEASGLERVERALATELVNGVLRWQLQLDSRISLAYHHKLEAAAPVLRNIL
RLGAYQLLFLTKIPRWAAVNECVKLARKYKGERMAKLVNGVLRHLDGGNEAFEKLLQGRSQAEQLALQFSHPAWLIERWL
ATYGELKTRQLLHYNNQAPMMGFRINRLKADAKDFFDNPTFAAAMEPCELPYCFLSREFSLFETALQEGVLSVQNPTQAL
APLLLNPAPQSVVIDLCAAPGGKAMFMAELMHNQGEVIAVDQYEQKLRKLESHAQALGLTIIRTVAGDARSVAPNLQADA
VLLDAPCSGTGVIGRRAELRWKVTPAMVAELQGLQAELLDHAATLLKPQGRLVYATCSIEPEENGEQVAAFLQRHPNFVA
EPHAQHMTLPGDRYGYDGGFCQCLRKLQE

Sequences:

>Translated_429_residues
MSTAREVALQVLQALEKSSERSDALLHKHLEASGLERVERALATELVNGVLRWQLQLDSRISLAYHHKLEAAAPVLRNIL
RLGAYQLLFLTKIPRWAAVNECVKLARKYKGERMAKLVNGVLRHLDGGNEAFEKLLQGRSQAEQLALQFSHPAWLIERWL
ATYGELKTRQLLHYNNQAPMMGFRINRLKADAKDFFDNPTFAAAMEPCELPYCFLSREFSLFETALQEGVLSVQNPTQAL
APLLLNPAPQSVVIDLCAAPGGKAMFMAELMHNQGEVIAVDQYEQKLRKLESHAQALGLTIIRTVAGDARSVAPNLQADA
VLLDAPCSGTGVIGRRAELRWKVTPAMVAELQGLQAELLDHAATLLKPQGRLVYATCSIEPEENGEQVAAFLQRHPNFVA
EPHAQHMTLPGDRYGYDGGFCQCLRKLQE
>Mature_428_residues
STAREVALQVLQALEKSSERSDALLHKHLEASGLERVERALATELVNGVLRWQLQLDSRISLAYHHKLEAAAPVLRNILR
LGAYQLLFLTKIPRWAAVNECVKLARKYKGERMAKLVNGVLRHLDGGNEAFEKLLQGRSQAEQLALQFSHPAWLIERWLA
TYGELKTRQLLHYNNQAPMMGFRINRLKADAKDFFDNPTFAAAMEPCELPYCFLSREFSLFETALQEGVLSVQNPTQALA
PLLLNPAPQSVVIDLCAAPGGKAMFMAELMHNQGEVIAVDQYEQKLRKLESHAQALGLTIIRTVAGDARSVAPNLQADAV
LLDAPCSGTGVIGRRAELRWKVTPAMVAELQGLQAELLDHAATLLKPQGRLVYATCSIEPEENGEQVAAFLQRHPNFVAE
PHAQHMTLPGDRYGYDGGFCQCLRKLQE

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=212, Percent_Identity=39.622641509434, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI8922322, Length=196, Percent_Identity=35.7142857142857, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI270288816, Length=196, Percent_Identity=35.7142857142857, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI270288818, Length=196, Percent_Identity=35.7142857142857, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI23199998, Length=196, Percent_Identity=35.7142857142857, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI39995082, Length=195, Percent_Identity=32.8205128205128, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI301336155, Length=195, Percent_Identity=32.8205128205128, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI76150625, Length=157, Percent_Identity=36.3057324840764, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI76150623, Length=157, Percent_Identity=36.3057324840764, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI2367212, Length=373, Percent_Identity=34.3163538873995, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI87081985, Length=232, Percent_Identity=29.7413793103448, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71998419, Length=171, Percent_Identity=35.0877192982456, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115534021, Length=171, Percent_Identity=35.0877192982456, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536757, Length=172, Percent_Identity=36.6279069767442, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25143471, Length=183, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324268, Length=170, Percent_Identity=32.9411764705882, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319447, Length=198, Percent_Identity=30.8080808080808, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21356579, Length=168, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355201, Length=196, Percent_Identity=31.6326530612245, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24668781, Length=180, Percent_Identity=31.1111111111111, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356513, Length=180, Percent_Identity=31.1111111111111, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI22024126, Length=163, Percent_Identity=30.6748466257669, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920494, Length=180, Percent_Identity=32.7777777777778, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 47711; Mature: 47579

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAREVALQVLQALEKSSERSDALLHKHLEASGLERVERALATELVNGVLRWQLQLDSR
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
ISLAYHHKLEAAAPVLRNILRLGAYQLLFLTKIPRWAAVNECVKLARKYKGERMAKLVNG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHH
VLRHLDGGNEAFEKLLQGRSQAEQLALQFSHPAWLIERWLATYGELKTRQLLHYNNQAPM
HHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
MGFRINRLKADAKDFFDNPTFAAAMEPCELPYCFLSREFSLFETALQEGVLSVQNPTQAL
CCEEHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
APLLLNPAPQSVVIDLCAAPGGKAMFMAELMHNQGEVIAVDQYEQKLRKLESHAQALGLT
HHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHH
IIRTVAGDARSVAPNLQADAVLLDAPCSGTGVIGRRAELRWKVTPAMVAELQGLQAELLD
HHHHHCCCHHHCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHH
HAATLLKPQGRLVYATCSIEPEENGEQVAAFLQRHPNFVAEPHAQHMTLPGDRYGYDGGF
HHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
CQCLRKLQE
HHHHHHHCC
>Mature Secondary Structure 
STAREVALQVLQALEKSSERSDALLHKHLEASGLERVERALATELVNGVLRWQLQLDSR
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
ISLAYHHKLEAAAPVLRNILRLGAYQLLFLTKIPRWAAVNECVKLARKYKGERMAKLVNG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHH
VLRHLDGGNEAFEKLLQGRSQAEQLALQFSHPAWLIERWLATYGELKTRQLLHYNNQAPM
HHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
MGFRINRLKADAKDFFDNPTFAAAMEPCELPYCFLSREFSLFETALQEGVLSVQNPTQAL
CCEEHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
APLLLNPAPQSVVIDLCAAPGGKAMFMAELMHNQGEVIAVDQYEQKLRKLESHAQALGLT
HHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHH
IIRTVAGDARSVAPNLQADAVLLDAPCSGTGVIGRRAELRWKVTPAMVAELQGLQAELLD
HHHHHCCCHHHCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHH
HAATLLKPQGRLVYATCSIEPEENGEQVAAFLQRHPNFVAEPHAQHMTLPGDRYGYDGGF
HHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
CQCLRKLQE
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]