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The map label for this gene is hxuB [H]

Identifier: 78189021

GI number: 78189021

Start: 1429504

End: 1431234

Strand: Reverse

Name: hxuB [H]

Synonym: Cag_1054

Alternate gene names: 78189021

Gene position: 1431234-1429504 (Counterclockwise)

Preceding gene: 78189022

Following gene: 78189020

Centisome position: 55.65

GC content: 46.45

Gene sequence:

>1731_bases
ATGGTTCCAAAAATTATAACATCGCTTGTAACGGGGAGTATTATGTTATCGGCTTCTCTTCAAGCCGCTCCGTATGTACC
TGATGCGGGCAGCTTACAGCAGCAGCAACGTCCAGCAGCCGTCTCTAAGCAGAAAAAACAAATGGTTCAAGACAACAAAG
GAAAGAGTGAGCCCAGCAAGCCCTTTGTTATTAAGCCATCGGCAAATGCTAAGGTTCCCGTTAAGCGCTTTACTTTTTCA
GGGTATGAAGGAACCGTGTCGCGAAGTGAGTTACAGGATATGGTAAAGCCTTATGTCGGTAAAAACCTTAGTATGGAGCA
GCTCCATGCTGTTTCTGCAAACATCACTTCTGAACTTCGTGCAAAAGGATGGTTGGCATCAGCAACCTTGCCGCCGCAAG
ATGTTACCGCGGGCACCGTGCATATTACTATCAATAGCGGTAAAACGGCAATGACCTCCATTACAGGCGATGAATCGGTT
CGCATTTGCGAGCGTCCACTTCGCCAAATTGCTGAAAAAACCTGTCCTTCAGGTTCTCCTCTTAATACTGACGATCAAGA
GCGTGCGGTGCTTTTGATGAATGATATTCCCGGCATTGCTGCCACCACATCGCTCTCAAAAGGGATGCTGGCAGGCACAA
CCGATGTTAATTACCTTATTCGCGAAGGTGCCTTGCTTTCAGGTGTGCTTTGGGGCGACAACTATGGTAACCGTTACACC
GGTACATGGACCCAAAATGCTGTATTGAACATTAATGATCCTATTCACTATGGCGAGCAATTCTCGCTTAATGTTGGTCA
TTCGGCTGGTATGTGGCGAGGTGGCGTAAATTATCGGGTGCCAATGCCATTTCTTTTTGCAGGCTTAACTGGTCATACGG
GTGTTTCGGGAATGCAATATGAGTTGCTTGAGGACTTTGAAGTGCTTGATTACGAAGGTAGCAGCATTAATGTTGATGCT
GGATTAAGTTACGCATTGCTTCGTAGCCGTAAAGCAAATCTTACCTCCGATGTTTCTTACACCTACAAAGGCTTAAAAGA
CTCGATGGGTAACACCGATTTACGCGATGGCACTATTCAAAGTGTAACTTTTGGTTTATCGGGCAATTACCGCGATGACC
TCTTTTTTGGAGCGTTAACAACGGCTGACTTAAGCATTACAAATGGTTCGCTTGAAGAGAAAATTCGCGATATCAGCTTA
AGTAATTCGGAAGGCGGTTACACCCGCTTAAACATGGGGTTAGCTCGTTATCAACGCTTTTCTGAACCATTTGTGCTTGA
CCTCGCCTTTTCTGCCCAACGTGCATTAAATAATCTTGATAGCAGCGAAAAATTCTTCCTTGGCGGTCCACAGCGTGTTC
GCGCTTACCCGCTTGGTGAGGCGGCGGGCGATCACGGTGCACTTTTTAAAGCCGACTTCCGTCACCGCATTTCTGTACCA
GAGGAGTGGGGCGATATGTTTGTTAACGCCTTTTACGATGCTGGTCATGTTACCCTTAACAAAGATCGTTATGCAAGTGA
TTCTGCAACTATCACCGCTACCGGTCGTAACGACTATTGGTTGCAAGGTGCAGGTTTAGGGCTTCGCTACGATATTTCGG
AAAACTTTACCCTACAAGGGTGCTGGGCACATACCATTGGTAAAAACTCTGGTCGCTCGGTGGATGGCAATAACTCTGAT
GGCAAGAGCGATAACAATCGCTTTTGGGTTCAGGGGCTCTACTATTTCTAA

Upstream 100 bases:

>100_bases
GACAGCTTGATGCTTTACGTTGGTTAGCGTAAAGCATAGAGGGCATCAACGAAAGATTGTAATATCCTGACACCTTAACC
ACAAAGGGAGATAACGCAAC

Downstream 100 bases:

>100_bases
TATCGAATGAAGCGTTTAAACAAACTTAGCCGTTATCGGTTTTTCCATAACTATTTGAGAGAAAAACAATGAATAGGGTA
TTTAATGTGATCTGGTCAAT

Product: activation/secretion signal peptide protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MVPKIITSLVTGSIMLSASLQAAPYVPDAGSLQQQQRPAAVSKQKKQMVQDNKGKSEPSKPFVIKPSANAKVPVKRFTFS
GYEGTVSRSELQDMVKPYVGKNLSMEQLHAVSANITSELRAKGWLASATLPPQDVTAGTVHITINSGKTAMTSITGDESV
RICERPLRQIAEKTCPSGSPLNTDDQERAVLLMNDIPGIAATTSLSKGMLAGTTDVNYLIREGALLSGVLWGDNYGNRYT
GTWTQNAVLNINDPIHYGEQFSLNVGHSAGMWRGGVNYRVPMPFLFAGLTGHTGVSGMQYELLEDFEVLDYEGSSINVDA
GLSYALLRSRKANLTSDVSYTYKGLKDSMGNTDLRDGTIQSVTFGLSGNYRDDLFFGALTTADLSITNGSLEEKIRDISL
SNSEGGYTRLNMGLARYQRFSEPFVLDLAFSAQRALNNLDSSEKFFLGGPQRVRAYPLGEAAGDHGALFKADFRHRISVP
EEWGDMFVNAFYDAGHVTLNKDRYASDSATITATGRNDYWLQGAGLGLRYDISENFTLQGCWAHTIGKNSGRSVDGNNSD
GKSDNNRFWVQGLYYF

Sequences:

>Translated_576_residues
MVPKIITSLVTGSIMLSASLQAAPYVPDAGSLQQQQRPAAVSKQKKQMVQDNKGKSEPSKPFVIKPSANAKVPVKRFTFS
GYEGTVSRSELQDMVKPYVGKNLSMEQLHAVSANITSELRAKGWLASATLPPQDVTAGTVHITINSGKTAMTSITGDESV
RICERPLRQIAEKTCPSGSPLNTDDQERAVLLMNDIPGIAATTSLSKGMLAGTTDVNYLIREGALLSGVLWGDNYGNRYT
GTWTQNAVLNINDPIHYGEQFSLNVGHSAGMWRGGVNYRVPMPFLFAGLTGHTGVSGMQYELLEDFEVLDYEGSSINVDA
GLSYALLRSRKANLTSDVSYTYKGLKDSMGNTDLRDGTIQSVTFGLSGNYRDDLFFGALTTADLSITNGSLEEKIRDISL
SNSEGGYTRLNMGLARYQRFSEPFVLDLAFSAQRALNNLDSSEKFFLGGPQRVRAYPLGEAAGDHGALFKADFRHRISVP
EEWGDMFVNAFYDAGHVTLNKDRYASDSATITATGRNDYWLQGAGLGLRYDISENFTLQGCWAHTIGKNSGRSVDGNNSD
GKSDNNRFWVQGLYYF
>Mature_576_residues
MVPKIITSLVTGSIMLSASLQAAPYVPDAGSLQQQQRPAAVSKQKKQMVQDNKGKSEPSKPFVIKPSANAKVPVKRFTFS
GYEGTVSRSELQDMVKPYVGKNLSMEQLHAVSANITSELRAKGWLASATLPPQDVTAGTVHITINSGKTAMTSITGDESV
RICERPLRQIAEKTCPSGSPLNTDDQERAVLLMNDIPGIAATTSLSKGMLAGTTDVNYLIREGALLSGVLWGDNYGNRYT
GTWTQNAVLNINDPIHYGEQFSLNVGHSAGMWRGGVNYRVPMPFLFAGLTGHTGVSGMQYELLEDFEVLDYEGSSINVDA
GLSYALLRSRKANLTSDVSYTYKGLKDSMGNTDLRDGTIQSVTFGLSGNYRDDLFFGALTTADLSITNGSLEEKIRDISL
SNSEGGYTRLNMGLARYQRFSEPFVLDLAFSAQRALNNLDSSEKFFLGGPQRVRAYPLGEAAGDHGALFKADFRHRISVP
EEWGDMFVNAFYDAGHVTLNKDRYASDSATITATGRNDYWLQGAGLGLRYDISENFTLQGCWAHTIGKNSGRSVDGNNSD
GKSDNNRFWVQGLYYF

Specific function: Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of huxA [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2 [H]

EC number: NA

Molecular weight: Translated: 62850; Mature: 62850

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPKIITSLVTGSIMLSASLQAAPYVPDAGSLQQQQRPAAVSKQKKQMVQDNKGKSEPSK
CCHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
PFVIKPSANAKVPVKRFTFSGYEGTVSRSELQDMVKPYVGKNLSMEQLHAVSANITSELR
CEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AKGWLASATLPPQDVTAGTVHITINSGKTAMTSITGDESVRICERPLRQIAEKTCPSGSP
HCCEEEECCCCCCCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCC
LNTDDQERAVLLMNDIPGIAATTSLSKGMLAGTTDVNYLIREGALLSGVLWGDNYGNRYT
CCCCCCCCEEEEEECCCCCEEEHHHCCCCEECCCCHHHHHHCCCEEEEEEECCCCCCCEE
GTWTQNAVLNINDPIHYGEQFSLNVGHSAGMWRGGVNYRVPMPFLFAGLTGHTGVSGMQY
CEECCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEECCCHHEEECCCCCCCCCCCHH
ELLEDFEVLDYEGSSINVDAGLSYALLRSRKANLTSDVSYTYKGLKDSMGNTDLRDGTIQ
HHHCCCEEEECCCCEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEE
SVTFGLSGNYRDDLFFGALTTADLSITNGSLEEKIRDISLSNSEGGYTRLNMGLARYQRF
EEEEECCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHC
SEPFVLDLAFSAQRALNNLDSSEKFFLGGPQRVRAYPLGEAAGDHGALFKADFRHRISVP
CCCEEEEEHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCCCCCEEEECCHHCCCCC
EEWGDMFVNAFYDAGHVTLNKDRYASDSATITATGRNDYWLQGAGLGLRYDISENFTLQG
HHHHHHHHHHEECCCCEEECCCCCCCCCEEEEEECCCCEEEEECCCEEEEECCCCCEEEE
CWAHTIGKNSGRSVDGNNSDGKSDNNRFWVQGLYYF
EEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MVPKIITSLVTGSIMLSASLQAAPYVPDAGSLQQQQRPAAVSKQKKQMVQDNKGKSEPSK
CCHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
PFVIKPSANAKVPVKRFTFSGYEGTVSRSELQDMVKPYVGKNLSMEQLHAVSANITSELR
CEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AKGWLASATLPPQDVTAGTVHITINSGKTAMTSITGDESVRICERPLRQIAEKTCPSGSP
HCCEEEECCCCCCCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCC
LNTDDQERAVLLMNDIPGIAATTSLSKGMLAGTTDVNYLIREGALLSGVLWGDNYGNRYT
CCCCCCCCEEEEEECCCCCEEEHHHCCCCEECCCCHHHHHHCCCEEEEEEECCCCCCCEE
GTWTQNAVLNINDPIHYGEQFSLNVGHSAGMWRGGVNYRVPMPFLFAGLTGHTGVSGMQY
CEECCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEECCCHHEEECCCCCCCCCCCHH
ELLEDFEVLDYEGSSINVDAGLSYALLRSRKANLTSDVSYTYKGLKDSMGNTDLRDGTIQ
HHHCCCEEEECCCCEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEE
SVTFGLSGNYRDDLFFGALTTADLSITNGSLEEKIRDISLSNSEGGYTRLNMGLARYQRF
EEEEECCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHC
SEPFVLDLAFSAQRALNNLDSSEKFFLGGPQRVRAYPLGEAAGDHGALFKADFRHRISVP
CCCEEEEEHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCCCCCEEEECCHHCCCCC
EEWGDMFVNAFYDAGHVTLNKDRYASDSATITATGRNDYWLQGAGLGLRYDISENFTLQG
HHHHHHHHHHEECCCCEEECCCCCCCCCEEEEEECCCCEEEEECCCEEEEECCCCCEEEE
CWAHTIGKNSGRSVDGNNSDGKSDNNRFWVQGLYYF
EEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]