Click here to switch to the map view.

The map label for this gene is yhfN [H]

Identifier: 78188909

GI number: 78188909

Start: 1276984

End: 1278252

Strand: Reverse

Name: yhfN [H]

Synonym: Cag_0941

Alternate gene names: 78188909

Gene position: 1278252-1276984 (Counterclockwise)

Preceding gene: 78188910

Following gene: 78188908

Centisome position: 49.7

GC content: 45.94

Gene sequence:

>1269_bases
ATGAATATTTTTGGTGTTGCTATTTTTATTACCCTCTTCACCACCTTTCTTGTTAAGGTTATTTCGGAACTGCTGAATCT
TCGAGCAGCCGCCTCGCCCTTACCATCCGAATATGCTGCACTTGCCGATAACGCAACGCGCCAAAAGTCGCGCGACTACC
TTGCGGCAACAACTCGCCTTTCACTCTTTAGCGCAGGCTTCGACCTTATAGCGCTCATTATTTTTTGGTTTAGCGGCAGC
TTTAACCTGCTTGATCAAACTTTGCGTAGTTTGGGCTTTAACTCCATTATAACGGGAATGCTGTACATTGGCACATTAAT
GCTGGTGCAATCCATTATTGAATTGCCCTTTAGCCTTGTTCGCACTTTTATTGTTGAAGAGAAATTTGGCTTTAACAAAA
CCACCATTGGCGTTTTTCTTGGCGATTTAGCTAAAACCGCCTTGCTCTCCATTATTATTGGGCTCCCTGTTTTAGCCGCT
TTGCTATGGTTTTTTGAAAGTGCGGGCAACCTTGCTTGGCTATGGGCGTGGAGTGGCATTGTACTGTTTTCGCTGTTGCT
GCAATACATTGCCCCAACATGGATTATGCCCATGTTCAACACCTTTAAACCGTTGCTTGATAATGAGTTAAGCCGTGCCA
TTATGCAGTATTCCGCTAAGGTACAGTTCCCCCTTTCAGGTATTTTTGAAATTGACGGCTCCAAGCGCTCCTCAAAAGCC
AATGCCTTTTTTACAGGCTTTGGCAAACGCAAGCGCATTGCGTTGTACGATACGCTGATTAAAGCACATCCCGTGCCAGA
ACTTGTTGCCGTGCTTGCGCACGAAATTGGGCACTTTAAGAAAAAGCACATTCTTATTAACCTCCTAATGAGTAGCGCCA
ACCTTGCCTTGCTCTTTTTCTTGCTTTCGCTGATGATGCATAATCGTCAGCTTTTTGATGCCTTTTTTATGGAGGAAACC
TCCGTGTATGGCAGCTTGCTTTTCTTTACCCTGCTTTACACTCCCGCCGAACTGATGCTCTCGGTGTTTATGCACGCCAT
TTCGCGTAAGCATGAATATGAAGCTGATGCCTTTGCGGTAACCACCTATGAGCAGGGGAGTGCGCTTGCCGATGCACTGC
TGAAGCTATCGCACCATAACCTCTCGAACTTAACACCGCATCCGCTCTACGTTTTTCTCAACTATTCGCACCCACCTGTG
GTGGAACGGTTACAGCGTATTAAAGCGCTCCTTGCATCCCAAACTCAACGTTCAACCCCAACGTTATAA

Upstream 100 bases:

>100_bases
ACGTTTTCTTGATAATAATCAATAATGAACTGTAGAAACAACGTATGCGTTGTCTCTACAATCATGGAATTAAAATTTTC
ATCCTACGATAGTTTACTCT

Downstream 100 bases:

>100_bases
GCTATGCCTACCACTTATCATATGCCGCCCGAATGGGCATTGCATCAAGCAACATGGCTCTCTTGGCCTCATAAATTGGA
ATCGTGGCCCGGTAAATTTG

Product: CAAX prenyl protease 1

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MNIFGVAIFITLFTTFLVKVISELLNLRAAASPLPSEYAALADNATRQKSRDYLAATTRLSLFSAGFDLIALIIFWFSGS
FNLLDQTLRSLGFNSIITGMLYIGTLMLVQSIIELPFSLVRTFIVEEKFGFNKTTIGVFLGDLAKTALLSIIIGLPVLAA
LLWFFESAGNLAWLWAWSGIVLFSLLLQYIAPTWIMPMFNTFKPLLDNELSRAIMQYSAKVQFPLSGIFEIDGSKRSSKA
NAFFTGFGKRKRIALYDTLIKAHPVPELVAVLAHEIGHFKKKHILINLLMSSANLALLFFLLSLMMHNRQLFDAFFMEET
SVYGSLLFFTLLYTPAELMLSVFMHAISRKHEYEADAFAVTTYEQGSALADALLKLSHHNLSNLTPHPLYVFLNYSHPPV
VERLQRIKALLASQTQRSTPTL

Sequences:

>Translated_422_residues
MNIFGVAIFITLFTTFLVKVISELLNLRAAASPLPSEYAALADNATRQKSRDYLAATTRLSLFSAGFDLIALIIFWFSGS
FNLLDQTLRSLGFNSIITGMLYIGTLMLVQSIIELPFSLVRTFIVEEKFGFNKTTIGVFLGDLAKTALLSIIIGLPVLAA
LLWFFESAGNLAWLWAWSGIVLFSLLLQYIAPTWIMPMFNTFKPLLDNELSRAIMQYSAKVQFPLSGIFEIDGSKRSSKA
NAFFTGFGKRKRIALYDTLIKAHPVPELVAVLAHEIGHFKKKHILINLLMSSANLALLFFLLSLMMHNRQLFDAFFMEET
SVYGSLLFFTLLYTPAELMLSVFMHAISRKHEYEADAFAVTTYEQGSALADALLKLSHHNLSNLTPHPLYVFLNYSHPPV
VERLQRIKALLASQTQRSTPTL
>Mature_422_residues
MNIFGVAIFITLFTTFLVKVISELLNLRAAASPLPSEYAALADNATRQKSRDYLAATTRLSLFSAGFDLIALIIFWFSGS
FNLLDQTLRSLGFNSIITGMLYIGTLMLVQSIIELPFSLVRTFIVEEKFGFNKTTIGVFLGDLAKTALLSIIIGLPVLAA
LLWFFESAGNLAWLWAWSGIVLFSLLLQYIAPTWIMPMFNTFKPLLDNELSRAIMQYSAKVQFPLSGIFEIDGSKRSSKA
NAFFTGFGKRKRIALYDTLIKAHPVPELVAVLAHEIGHFKKKHILINLLMSSANLALLFFLLSLMMHNRQLFDAFFMEET
SVYGSLLFFTLLYTPAELMLSVFMHAISRKHEYEADAFAVTTYEQGSALADALLKLSHHNLSNLTPHPLYVFLNYSHPPV
VERLQRIKALLASQTQRSTPTL

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=459, Percent_Identity=30.2832244008715, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17505484, Length=408, Percent_Identity=31.1274509803922, Blast_Score=184, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6322577, Length=410, Percent_Identity=35.8536585365854, Blast_Score=206, Evalue=4e-54,
Organism=Drosophila melanogaster, GI19922414, Length=409, Percent_Identity=30.0733496332518, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24654305, Length=299, Percent_Identity=28.4280936454849, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI78707252, Length=398, Percent_Identity=23.8693467336683, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI78707254, Length=398, Percent_Identity=23.8693467336683, Blast_Score=89, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 47362; Mature: 47362

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFGVAIFITLFTTFLVKVISELLNLRAAASPLPSEYAALADNATRQKSRDYLAATTRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
SLFSAGFDLIALIIFWFSGSFNLLDQTLRSLGFNSIITGMLYIGTLMLVQSIIELPFSLV
HHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTFIVEEKFGFNKTTIGVFLGDLAKTALLSIIIGLPVLAALLWFFESAGNLAWLWAWSGI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHH
VLFSLLLQYIAPTWIMPMFNTFKPLLDNELSRAIMQYSAKVQFPLSGIFEIDGSKRSSKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEECCCCCCCCC
NAFFTGFGKRKRIALYDTLIKAHPVPELVAVLAHEIGHFKKKHILINLLMSSANLALLFF
CHHEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LLSLMMHNRQLFDAFFMEETSVYGSLLFFTLLYTPAELMLSVFMHAISRKHEYEADAFAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCEEE
TTYEQGSALADALLKLSHHNLSNLTPHPLYVFLNYSHPPVVERLQRIKALLASQTQRSTP
EEECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
TL
CC
>Mature Secondary Structure
MNIFGVAIFITLFTTFLVKVISELLNLRAAASPLPSEYAALADNATRQKSRDYLAATTRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
SLFSAGFDLIALIIFWFSGSFNLLDQTLRSLGFNSIITGMLYIGTLMLVQSIIELPFSLV
HHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTFIVEEKFGFNKTTIGVFLGDLAKTALLSIIIGLPVLAALLWFFESAGNLAWLWAWSGI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHH
VLFSLLLQYIAPTWIMPMFNTFKPLLDNELSRAIMQYSAKVQFPLSGIFEIDGSKRSSKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEECCCCCCCCC
NAFFTGFGKRKRIALYDTLIKAHPVPELVAVLAHEIGHFKKKHILINLLMSSANLALLFF
CHHEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LLSLMMHNRQLFDAFFMEETSVYGSLLFFTLLYTPAELMLSVFMHAISRKHEYEADAFAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCEEE
TTYEQGSALADALLKLSHHNLSNLTPHPLYVFLNYSHPPVVERLQRIKALLASQTQRSTP
EEECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
TL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]