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The map label for this gene is purQ

Identifier: 78188905

GI number: 78188905

Start: 1273704

End: 1274408

Strand: Reverse

Name: purQ

Synonym: Cag_0937

Alternate gene names: 78188905

Gene position: 1274408-1273704 (Counterclockwise)

Preceding gene: 78188906

Following gene: 78188904

Centisome position: 49.55

GC content: 47.09

Gene sequence:

>705_bases
ATGTCTGCTATTACTGTAGGAGTTGTTGTTTTCCCGGGTTCCAATTGCGACCACGATACTGCTTATGCGCTTGCTTCTTT
TGCGGGCGTTAAGCCGGTGATGTTGTGGCATAACAACCACGATTTGCAAGGAGCACAAGCTATTGTGTTACCGGGCGGCT
TCTCATATGGCGATTATTTGCGTGCTGGTGCTATTGCTCGTTTTTCGCCTCTTATGAAAGAGGTTGTGGAATTTGCTCGC
AAGGGTTATCCCGTGCTTGGTATTTGTAACGGCTTTCAAGTATTGCTTGAAAGTGGCTTGCTTGAAGGTGCGTTGTCGCG
CAATCGCGATAAAAAATTTCTCTGCTGTCAAACAACTATTACCCCCGTTAATTGCTCTACCCGTTTTACGGAGGATTATC
ATCAAGGCGAAGTGCTTCGTATTCCCATTGCGCATGGTGAAGGCAACTATTTTGCACCGCCTGAGGTGTTGGAAAGTTTG
CAAGAGCACAATCAAATTGCTTTTCAATATTGCAATGCGCAGGGTGAAGTTACCGTTGAAGCCAATCCAAACGGCTCTCT
TTTAAATATTGCAGGCATTGTGAATCGTGCGGGTAATGTGTTGGGGTTAATGCCGCATCCCGAACGGGCAAGCGATGCCG
CGCTTGGCTCGGTTGATGGACGCTTGCTTTTTGAGTCGCTTTTTCGCTCTTTAACGGGCGTATAA

Upstream 100 bases:

>100_bases
GAGTTGGAGCCTTTAGCGTAGCGAGTCATTGTAACGGATAGGTTCATTTTGTGCTTTTTTAAGCGTTCTGCTGCAACTGC
AATTTTTCTTTTCAAGCCTT

Downstream 100 bases:

>100_bases
GGTTGTAGCCGCAATTCTCCTTTGCACTATGCAGCGTGCTTTTCGTGCTTTTACCCTTCGCCGTAAGCGCTTGCAAGCTC
AGCGCAACTATCAAATCCTT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSAITVGVVVFPGSNCDHDTAYALASFAGVKPVMLWHNNHDLQGAQAIVLPGGFSYGDYLRAGAIARFSPLMKEVVEFAR
KGYPVLGICNGFQVLLESGLLEGALSRNRDKKFLCCQTTITPVNCSTRFTEDYHQGEVLRIPIAHGEGNYFAPPEVLESL
QEHNQIAFQYCNAQGEVTVEANPNGSLLNIAGIVNRAGNVLGLMPHPERASDAALGSVDGRLLFESLFRSLTGV

Sequences:

>Translated_234_residues
MSAITVGVVVFPGSNCDHDTAYALASFAGVKPVMLWHNNHDLQGAQAIVLPGGFSYGDYLRAGAIARFSPLMKEVVEFAR
KGYPVLGICNGFQVLLESGLLEGALSRNRDKKFLCCQTTITPVNCSTRFTEDYHQGEVLRIPIAHGEGNYFAPPEVLESL
QEHNQIAFQYCNAQGEVTVEANPNGSLLNIAGIVNRAGNVLGLMPHPERASDAALGSVDGRLLFESLFRSLTGV
>Mature_233_residues
SAITVGVVVFPGSNCDHDTAYALASFAGVKPVMLWHNNHDLQGAQAIVLPGGFSYGDYLRAGAIARFSPLMKEVVEFARK
GYPVLGICNGFQVLLESGLLEGALSRNRDKKFLCCQTTITPVNCSTRFTEDYHQGEVLRIPIAHGEGNYFAPPEVLESLQ
EHNQIAFQYCNAQGEVTVEANPNGSLLNIAGIVNRAGNVLGLMPHPERASDAALGSVDGRLLFESLFRSLTGV

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=183, Percent_Identity=32.2404371584699, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321498, Length=180, Percent_Identity=33.8888888888889, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24582111, Length=187, Percent_Identity=33.1550802139037, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582109, Length=187, Percent_Identity=33.1550802139037, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17137292, Length=187, Percent_Identity=33.1550802139037, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_CHLCH (Q3AS25)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_379243.1
- ProteinModelPortal:   Q3AS25
- STRING:   Q3AS25
- GeneID:   3747090
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_0937
- eggNOG:   COG0047
- HOGENOM:   HBG302712
- OMA:   FPGTNCD
- ProtClustDB:   PRK03619
- BioCyc:   CCHL340177:CAG_0937-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF07685 GATase_3

EC number: =6.3.5.3

Molecular weight: Translated: 25225; Mature: 25094

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS51273 GATASE_TYPE_1; PS00442 GATASE_TYPE_I

Important sites: ACT_SITE 89-89 ACT_SITE 206-206 ACT_SITE 208-208

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAITVGVVVFPGSNCDHDTAYALASFAGVKPVMLWHNNHDLQGAQAIVLPGGFSYGDYL
CCCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHH
RAGAIARFSPLMKEVVEFARKGYPVLGICNGFQVLLESGLLEGALSRNRDKKFLCCQTTI
HHCHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEECEE
TPVNCSTRFTEDYHQGEVLRIPIAHGEGNYFAPPEVLESLQEHNQIAFQYCNAQGEVTVE
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCCEEEE
ANPNGSLLNIAGIVNRAGNVLGLMPHPERASDAALGSVDGRLLFESLFRSLTGV
ECCCCCEEEHHHHHHCCCCEEEECCCCCCCCCCHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAITVGVVVFPGSNCDHDTAYALASFAGVKPVMLWHNNHDLQGAQAIVLPGGFSYGDYL
CCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHH
RAGAIARFSPLMKEVVEFARKGYPVLGICNGFQVLLESGLLEGALSRNRDKKFLCCQTTI
HHCHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEECEE
TPVNCSTRFTEDYHQGEVLRIPIAHGEGNYFAPPEVLESLQEHNQIAFQYCNAQGEVTVE
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCCEEEE
ANPNGSLLNIAGIVNRAGNVLGLMPHPERASDAALGSVDGRLLFESLFRSLTGV
ECCCCCEEEHHHHHHCCCCEEEECCCCCCCCCCHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA