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The map label for this gene is dnaX [H]

Identifier: 78188902

GI number: 78188902

Start: 1269562

End: 1270752

Strand: Reverse

Name: dnaX [H]

Synonym: Cag_0934

Alternate gene names: 78188902

Gene position: 1270752-1269562 (Counterclockwise)

Preceding gene: 78188903

Following gene: 78188901

Centisome position: 49.41

GC content: 46.68

Gene sequence:

>1191_bases
ATGAGTTACCAAGTTATTGCACGAAAATATCGTCCAGCAAAATTTTCGGATATTACTGCCCAAGAGCATGTTACGCGCAC
CATTCAAAATGCTTTACGCTCAGGACGTATTGGGCATGGTTACATTTTTTCGGGCTTGCGTGGTGTGGGCAAAACAACGG
CAGCTCGCATTTTTGCACGGGCGCTGAATTGCCAAAAACTTATTGATGATGCCGATTACTTGCAACAAGTAACCGAGCCT
TGTGGCGAATGCGAAAGCTGTCGCGATTTTGATGCGGGCACCAGCATGAACATTTCGGAATTTGATGCTGCCTCCAACAA
CGGTGTGGATGATATTCGTACTCTACGCGAAAATGTGCGTTATGGACCTCAAAAAGGGAGGTACCGTGTCTATATTATTG
ATGAAGTACACATGCTCTCCATTGCGGCATTTAACGCTTTTTTAAAGACGCTTGAAGAGCCACCACCGCATGCTATTTTC
ATTTTTGCAACCACCGAGCTGCATAAAATTCCCCCAACCATCTCTTCGCGCTGCCAACGCTTTAACTTTAAGCGCATTCC
GCTTGAAGCTATTCAGCAGCAATTGCAACAAATTTGTGAAGCCGAGCATATTCAAGTTGAAGCCGATGCCTTGCAGCTTG
TTGCCCGCAAAGCACAAGGCTCCATGCGCGACGCTCAAAGCATTCTCGATCAAGTAATTGCCTTTTCATCTGAAAATGCG
CTTGAAGGCTCCATTACCTATCGAGGAGTGGCAGATTTGCTTAACTACATTGATGACGACACCATGTTTGCCGTTACCGA
TGCGGTGTTGGCAAACAATCCCGTTGCTATGCTTGAGGTGGCGCACTTTGTGTTAAAGAATGGCTATGATGAGCAAGATT
TTCTTGAAAAGCTGCTTGAGCATTTGCGCAACCTATTGGTGGTGCTGAACCTTTCATCCACCCGCCTTGTAGAGCGCCCC
GATGCCGTGCGTGAACGCTATCAGCGCGATGCGGCAAAATTCTCTCCCCATACTATTATGCAAATGGCGGAGCTGCTGTT
GCAAACCCAAAAAGAGCTGAAGTTTCTTTTTGAATATCAATTCCGTTTTGAGCTTGCCTTGCTTAAACTGCTTGAAATTG
CCCATCCGCCCGCCTCAGCGGCTGCACTTACCATAGCGCCTGAAAAAAAAAAGCCTCTAAGCAATCAGTAG

Upstream 100 bases:

>100_bases
CAAAAGACCCTTGAATTATTCAGGTTATCAAAAAGATTTTTTAGGGATATGAAAGAATCAGAGGCAAGCTATCAGTAGTT
CCATTATGATTGAATAAGCT

Downstream 100 bases:

>100_bases
CTTCCGCCTCCTCAGCCACCACAGCGGTTGTTGAGCAACCAACAACCGCTACATCAACGTCGCTATCTTCAGGTAACTCC
TCAGCCTCTAACACCGCTAC

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSYQVIARKYRPAKFSDITAQEHVTRTIQNALRSGRIGHGYIFSGLRGVGKTTAARIFARALNCQKLIDDADYLQQVTEP
CGECESCRDFDAGTSMNISEFDAASNNGVDDIRTLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF
IFATTELHKIPPTISSRCQRFNFKRIPLEAIQQQLQQICEAEHIQVEADALQLVARKAQGSMRDAQSILDQVIAFSSENA
LEGSITYRGVADLLNYIDDDTMFAVTDAVLANNPVAMLEVAHFVLKNGYDEQDFLEKLLEHLRNLLVVLNLSSTRLVERP
DAVRERYQRDAAKFSPHTIMQMAELLLQTQKELKFLFEYQFRFELALLKLLEIAHPPASAAALTIAPEKKKPLSNQ

Sequences:

>Translated_396_residues
MSYQVIARKYRPAKFSDITAQEHVTRTIQNALRSGRIGHGYIFSGLRGVGKTTAARIFARALNCQKLIDDADYLQQVTEP
CGECESCRDFDAGTSMNISEFDAASNNGVDDIRTLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF
IFATTELHKIPPTISSRCQRFNFKRIPLEAIQQQLQQICEAEHIQVEADALQLVARKAQGSMRDAQSILDQVIAFSSENA
LEGSITYRGVADLLNYIDDDTMFAVTDAVLANNPVAMLEVAHFVLKNGYDEQDFLEKLLEHLRNLLVVLNLSSTRLVERP
DAVRERYQRDAAKFSPHTIMQMAELLLQTQKELKFLFEYQFRFELALLKLLEIAHPPASAAALTIAPEKKKPLSNQ
>Mature_395_residues
SYQVIARKYRPAKFSDITAQEHVTRTIQNALRSGRIGHGYIFSGLRGVGKTTAARIFARALNCQKLIDDADYLQQVTEPC
GECESCRDFDAGTSMNISEFDAASNNGVDDIRTLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFI
FATTELHKIPPTISSRCQRFNFKRIPLEAIQQQLQQICEAEHIQVEADALQLVARKAQGSMRDAQSILDQVIAFSSENAL
EGSITYRGVADLLNYIDDDTMFAVTDAVLANNPVAMLEVAHFVLKNGYDEQDFLEKLLEHLRNLLVVLNLSSTRLVERPD
AVRERYQRDAAKFSPHTIMQMAELLLQTQKELKFLFEYQFRFELALLKLLEIAHPPASAAALTIAPEKKKPLSNQ

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI194306571, Length=228, Percent_Identity=25.8771929824561, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI194306567, Length=228, Percent_Identity=25.8771929824561, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI6677723, Length=246, Percent_Identity=26.0162601626016, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786676, Length=376, Percent_Identity=40.9574468085106, Blast_Score=285, Evalue=5e-78,
Organism=Escherichia coli, GI1787341, Length=160, Percent_Identity=30.625, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17554730, Length=221, Percent_Identity=28.0542986425339, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71986063, Length=311, Percent_Identity=24.1157556270096, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324478, Length=307, Percent_Identity=22.8013029315961, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324039, Length=224, Percent_Identity=24.1071428571429, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322528, Length=304, Percent_Identity=20.7236842105263, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 44766; Mature: 44635

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQVIARKYRPAKFSDITAQEHVTRTIQNALRSGRIGHGYIFSGLRGVGKTTAARIFAR
CCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHH
ALNCQKLIDDADYLQQVTEPCGECESCRDFDAGTSMNISEFDAASNNGVDDIRTLRENVR
HHHHHHHHCHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHC
YGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTELHKIPPTISSRCQR
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHCCCHHHHHHHH
FNFKRIPLEAIQQQLQQICEAEHIQVEADALQLVARKAQGSMRDAQSILDQVIAFSSENA
CCCCCCCHHHHHHHHHHHHCHHHEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
LEGSITYRGVADLLNYIDDDTMFAVTDAVLANNPVAMLEVAHFVLKNGYDEQDFLEKLLE
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
HLRNLLVVLNLSSTRLVERPDAVRERYQRDAAKFSPHTIMQMAELLLQTQKELKFLFEYQ
HHHHHHEEECCCCCHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
FRFELALLKLLEIAHPPASAAALTIAPEKKKPLSNQ
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SYQVIARKYRPAKFSDITAQEHVTRTIQNALRSGRIGHGYIFSGLRGVGKTTAARIFAR
CHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHH
ALNCQKLIDDADYLQQVTEPCGECESCRDFDAGTSMNISEFDAASNNGVDDIRTLRENVR
HHHHHHHHCHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHC
YGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTELHKIPPTISSRCQR
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHCCCHHHHHHHH
FNFKRIPLEAIQQQLQQICEAEHIQVEADALQLVARKAQGSMRDAQSILDQVIAFSSENA
CCCCCCCHHHHHHHHHHHHCHHHEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
LEGSITYRGVADLLNYIDDDTMFAVTDAVLANNPVAMLEVAHFVLKNGYDEQDFLEKLLE
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
HLRNLLVVLNLSSTRLVERPDAVRERYQRDAAKFSPHTIMQMAELLLQTQKELKFLFEYQ
HHHHHHEEECCCCCHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
FRFELALLKLLEIAHPPASAAALTIAPEKKKPLSNQ
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]