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The map label for this gene is cfiA [H]

Identifier: 78188829

GI number: 78188829

Start: 1189816

End: 1191768

Strand: Reverse

Name: cfiA [H]

Synonym: Cag_0859

Alternate gene names: 78188829

Gene position: 1191768-1189816 (Counterclockwise)

Preceding gene: 78188830

Following gene: 78188828

Centisome position: 46.33

GC content: 46.9

Gene sequence:

>1953_bases
ATGAAAAAAATACGTTTTATGGATGTCTCTTTTAGAGACGGTTTTCAGTCATGTTATGGTGCACGAGTTCGCACTGAGGA
TTTTTTGCCGGTGCTGGAAGCTGCTGTAGCGGCTGGTACTGATAACTTTGAAATTGGTGGTGGCGCTCGTTTTCAAAGCT
TATACTTTTATTGCGAAGAGGATGCTTTTGAAATGATGGATCGCGCACGCGAAGTGGTTGGTCCCGATATTAATTTGCAA
ACGCTTTCGCGTGGCGCAAACGTAGTCGGGCTTATTTCCCAATCGCGCGATATTATTGATCTTCATGCACGTCTTTTTAA
AAAGCATGGTATTTCAACCATTCGCAACTTTGATGCTTTAATGGATGTGCGTAACCTTGCCTATTCAGGGCAGTGTATTC
ACAATGCAGGCTTAAAACATCAAGTAGTTATTGCCTTAATGGGTTTAGCGCCAGGCTTAAAAGAAACCTACTGCCACACT
CCGCAATTCTATCTTGATAAATTACAAGAGATTCTTGATACCGGCATTCCTTTTGATAGCGTTGCTTTTAAGGATGCTTC
GGGCACAACAACTCCAGCCACCGTGTATGAAACCGTAAAAGGCGCACGCAAAATGTTGCCTTCTGAAACGGTGATTGAGT
TCCATACGCACGACACCGCAGGCATGGGCGTTGCTTGTAACTTTGCCGCTATTGAAGCTGGTGCCGACATTATTGACCTT
TCAATGGCTCCCGTAAGTGGTGGCACGGCTGAAGTTGACATTCTTACCATGTGGCAGCGCTTACGTGGCACCGATTATAC
GCTTGATATTGATCAAGAAAAATACTTGGAAGTTGAGTCGTTCTTTACCGAGCAAATGTACAAGTATTACATGCCGCCCG
AAGCCATAGCAGTAAATCCCATTATTACCTTTTCGCCCATGCCTGGCGGTGCGCTGACGGCGAACACCCAAATGATGCGC
GATAACAACACGCTTCATCTTTTCCCTGAAGTTATTAACAACATGCGCGAAGTGGTGGCAAAAGGTGGCTTTGGTGCCTC
GGTTACCCCTGTATCGCAATTTTACTTCCAGCAAGCCTTTGCAAATACCGTGCAAGGTGCTTGGAAAAAAATTACCGATG
GTTATGGTAAAATGGTGCTTGGCTACTTTGGGCACACCCCGTCGGAGCCTGACGAAGAGGTTGTTCGCATTGCCAGCGAA
CAGCTTGGTTTACCTCCAACCAAAGAGGATGTACACGACATTAACGACCGCAATCCAGAACTTGGTGTTGCTTATAACCG
TGCATTGCTTGAAAAAGAGGGGCTTCCAACCACTGAGGAAAACATCTTTATTGCAGCAACGTGCGGCGTAAAAGGCATTG
ACTTCTTAAAAGGCAACTGCTCAAACGGCATTCGCTATAAAGCCGATGTTGATCTTGAAATTAAAGCCAAACCAAAAGAG
GAAGTTGTTGCCGCTTACCACGAAGCGCACAAGCACGATGTGCATCAAACTGAGGTAAATCATCGTTTAACCGAGCTTTT
CTCTAAAACAGCGCCAGCCGCCGCTGCACCTGTAGCACCTGCAACTTCAGCCGCTAAGGTTATATCAATGGCGGGTTCTT
TCTCAATTTTTGTGGATGGAACGCCCTATTCGGTAACCTTTGCTGAAGGCTCTTCCATTAATCCGCAACATGTTGCTCCA
GCCACCCCAATGGTCCCAATGGCACAAGCGGCACCTGTGGCTGCTCCATCACCGCCAGTGGGAACGCCAGTACCAGCCGT
TATGCCGGGCAATATTTTCAAGCTTGATGTAAAGGTTGGCGATGAAGTACGAGAGGGCGATGAAGTTGCCGTGCTTGAAG
CCATGAAAATGGAAAACCCTGTGAAAGCACCATGTTCAGGCAAAGTGCTCTCCATTGCGGTAGCTAAAGGCGATACCGTT
GGAATGGGGCAGCCCATTATGTATATCGGGTAA

Upstream 100 bases:

>100_bases
CTACGCGAATTGGTTTTATTGATTGTGGATGTTGCATTTTAAATGTTGAATTGTAGGGGCGGAATCCATTTCCGCCCTTC
CTGAAAAAGAAAAATAGCCT

Downstream 100 bases:

>100_bases
AGCCTTGCCTTCCATTATTTTGTGCTATAAAACCCGTCAGCAGCCTTCGTGTTGTTGACGGGTTTTTGGTCTAACACCTG
CCTCTCTTTCTCTCTACAAT

Product: oxaloacetate decarboxylase subunit alpha

Products: NA

Alternate protein names: 2-oxoglutarate carboxylase alpha subunit [H]

Number of amino acids: Translated: 650; Mature: 650

Protein sequence:

>650_residues
MKKIRFMDVSFRDGFQSCYGARVRTEDFLPVLEAAVAAGTDNFEIGGGARFQSLYFYCEEDAFEMMDRAREVVGPDINLQ
TLSRGANVVGLISQSRDIIDLHARLFKKHGISTIRNFDALMDVRNLAYSGQCIHNAGLKHQVVIALMGLAPGLKETYCHT
PQFYLDKLQEILDTGIPFDSVAFKDASGTTTPATVYETVKGARKMLPSETVIEFHTHDTAGMGVACNFAAIEAGADIIDL
SMAPVSGGTAEVDILTMWQRLRGTDYTLDIDQEKYLEVESFFTEQMYKYYMPPEAIAVNPIITFSPMPGGALTANTQMMR
DNNTLHLFPEVINNMREVVAKGGFGASVTPVSQFYFQQAFANTVQGAWKKITDGYGKMVLGYFGHTPSEPDEEVVRIASE
QLGLPPTKEDVHDINDRNPELGVAYNRALLEKEGLPTTEENIFIAATCGVKGIDFLKGNCSNGIRYKADVDLEIKAKPKE
EVVAAYHEAHKHDVHQTEVNHRLTELFSKTAPAAAAPVAPATSAAKVISMAGSFSIFVDGTPYSVTFAEGSSINPQHVAP
ATPMVPMAQAAPVAAPSPPVGTPVPAVMPGNIFKLDVKVGDEVREGDEVAVLEAMKMENPVKAPCSGKVLSIAVAKGDTV
GMGQPIMYIG

Sequences:

>Translated_650_residues
MKKIRFMDVSFRDGFQSCYGARVRTEDFLPVLEAAVAAGTDNFEIGGGARFQSLYFYCEEDAFEMMDRAREVVGPDINLQ
TLSRGANVVGLISQSRDIIDLHARLFKKHGISTIRNFDALMDVRNLAYSGQCIHNAGLKHQVVIALMGLAPGLKETYCHT
PQFYLDKLQEILDTGIPFDSVAFKDASGTTTPATVYETVKGARKMLPSETVIEFHTHDTAGMGVACNFAAIEAGADIIDL
SMAPVSGGTAEVDILTMWQRLRGTDYTLDIDQEKYLEVESFFTEQMYKYYMPPEAIAVNPIITFSPMPGGALTANTQMMR
DNNTLHLFPEVINNMREVVAKGGFGASVTPVSQFYFQQAFANTVQGAWKKITDGYGKMVLGYFGHTPSEPDEEVVRIASE
QLGLPPTKEDVHDINDRNPELGVAYNRALLEKEGLPTTEENIFIAATCGVKGIDFLKGNCSNGIRYKADVDLEIKAKPKE
EVVAAYHEAHKHDVHQTEVNHRLTELFSKTAPAAAAPVAPATSAAKVISMAGSFSIFVDGTPYSVTFAEGSSINPQHVAP
ATPMVPMAQAAPVAAPSPPVGTPVPAVMPGNIFKLDVKVGDEVREGDEVAVLEAMKMENPVKAPCSGKVLSIAVAKGDTV
GMGQPIMYIG
>Mature_650_residues
MKKIRFMDVSFRDGFQSCYGARVRTEDFLPVLEAAVAAGTDNFEIGGGARFQSLYFYCEEDAFEMMDRAREVVGPDINLQ
TLSRGANVVGLISQSRDIIDLHARLFKKHGISTIRNFDALMDVRNLAYSGQCIHNAGLKHQVVIALMGLAPGLKETYCHT
PQFYLDKLQEILDTGIPFDSVAFKDASGTTTPATVYETVKGARKMLPSETVIEFHTHDTAGMGVACNFAAIEAGADIIDL
SMAPVSGGTAEVDILTMWQRLRGTDYTLDIDQEKYLEVESFFTEQMYKYYMPPEAIAVNPIITFSPMPGGALTANTQMMR
DNNTLHLFPEVINNMREVVAKGGFGASVTPVSQFYFQQAFANTVQGAWKKITDGYGKMVLGYFGHTPSEPDEEVVRIASE
QLGLPPTKEDVHDINDRNPELGVAYNRALLEKEGLPTTEENIFIAATCGVKGIDFLKGNCSNGIRYKADVDLEIKAKPKE
EVVAAYHEAHKHDVHQTEVNHRLTELFSKTAPAAAAPVAPATSAAKVISMAGSFSIFVDGTPYSVTFAEGSSINPQHVAP
ATPMVPMAQAAPVAAPSPPVGTPVPAVMPGNIFKLDVKVGDEVREGDEVAVLEAMKMENPVKAPCSGKVLSIAVAKGDTV
GMGQPIMYIG

Specific function: Unknown

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=279, Percent_Identity=27.2401433691756, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI106049295, Length=279, Percent_Identity=27.2401433691756, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI106049292, Length=279, Percent_Identity=27.2401433691756, Blast_Score=106, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17562816, Length=358, Percent_Identity=29.0502793296089, Blast_Score=102, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6321376, Length=313, Percent_Identity=30.9904153354633, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6319695, Length=313, Percent_Identity=30.6709265175719, Blast_Score=124, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24652212, Length=359, Percent_Identity=28.133704735376, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24652210, Length=359, Percent_Identity=28.133704735376, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24652214, Length=359, Percent_Identity=28.133704735376, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI19921944, Length=359, Percent_Identity=28.133704735376, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24652216, Length=359, Percent_Identity=28.133704735376, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI281363050, Length=359, Percent_Identity=28.133704735376, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24652224, Length=359, Percent_Identity=28.133704735376, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24652222, Length=359, Percent_Identity=28.133704735376, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24652220, Length=359, Percent_Identity=28.133704735376, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24652218, Length=359, Percent_Identity=28.133704735376, Blast_Score=115, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.7 [H]

Molecular weight: Translated: 70514; Mature: 70514

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIRFMDVSFRDGFQSCYGARVRTEDFLPVLEAAVAAGTDNFEIGGGARFQSLYFYCEE
CCCEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCCCCEEEEEEEEECH
DAFEMMDRAREVVGPDINLQTLSRGANVVGLISQSRDIIDLHARLFKKHGISTIRNFDAL
HHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHH
MDVRNLAYSGQCIHNAGLKHQVVIALMGLAPGLKETYCHTPQFYLDKLQEILDTGIPFDS
HHHHHHHCCCCCHHCCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCC
VAFKDASGTTTPATVYETVKGARKMLPSETVIEFHTHDTAGMGVACNFAAIEAGADIIDL
EEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEHHHHCCCCEEEE
SMAPVSGGTAEVDILTMWQRLRGTDYTLDIDQEKYLEVESFFTEQMYKYYMPPEAIAVNP
EECCCCCCCCEEHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEECC
IITFSPMPGGALTANTQMMRDNNTLHLFPEVINNMREVVAKGGFGASVTPVSQFYFQQAF
EEEECCCCCCCEECCCEEEECCCEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
ANTVQGAWKKITDGYGKMVLGYFGHTPSEPDEEVVRIASEQLGLPPTKEDVHDINDRNPE
HHHHHHHHHHHHCCHHHEEEHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCC
LGVAYNRALLEKEGLPTTEENIFIAATCGVKGIDFLKGNCSNGIRYKADVDLEIKAKPKE
CCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHCCCCCCCCEEEEECCEEEECCCHH
EVVAAYHEAHKHDVHQTEVNHRLTELFSKTAPAAAAPVAPATSAAKVISMAGSFSIFVDG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEECC
TPYSVTFAEGSSINPQHVAPATPMVPMAQAAPVAAPSPPVGTPVPAVMPGNIFKLDVKVG
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEC
DEVREGDEVAVLEAMKMENPVKAPCSGKVLSIAVAKGDTVGMGQPIMYIG
CCCCCCCCEEEHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEC
>Mature Secondary Structure
MKKIRFMDVSFRDGFQSCYGARVRTEDFLPVLEAAVAAGTDNFEIGGGARFQSLYFYCEE
CCCEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCCCCEEEEEEEEECH
DAFEMMDRAREVVGPDINLQTLSRGANVVGLISQSRDIIDLHARLFKKHGISTIRNFDAL
HHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHH
MDVRNLAYSGQCIHNAGLKHQVVIALMGLAPGLKETYCHTPQFYLDKLQEILDTGIPFDS
HHHHHHHCCCCCHHCCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCC
VAFKDASGTTTPATVYETVKGARKMLPSETVIEFHTHDTAGMGVACNFAAIEAGADIIDL
EEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEHHHHCCCCEEEE
SMAPVSGGTAEVDILTMWQRLRGTDYTLDIDQEKYLEVESFFTEQMYKYYMPPEAIAVNP
EECCCCCCCCEEHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEECC
IITFSPMPGGALTANTQMMRDNNTLHLFPEVINNMREVVAKGGFGASVTPVSQFYFQQAF
EEEECCCCCCCEECCCEEEECCCEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
ANTVQGAWKKITDGYGKMVLGYFGHTPSEPDEEVVRIASEQLGLPPTKEDVHDINDRNPE
HHHHHHHHHHHHCCHHHEEEHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCC
LGVAYNRALLEKEGLPTTEENIFIAATCGVKGIDFLKGNCSNGIRYKADVDLEIKAKPKE
CCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHCCCCCCCCEEEEECCEEEECCCHH
EVVAAYHEAHKHDVHQTEVNHRLTELFSKTAPAAAAPVAPATSAAKVISMAGSFSIFVDG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEECC
TPYSVTFAEGSSINPQHVAPATPMVPMAQAAPVAAPSPPVGTPVPAVMPGNIFKLDVKVG
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEC
DEVREGDEVAVLEAMKMENPVKAPCSGKVLSIAVAKGDTVGMGQPIMYIG
CCCCCCCCEEEHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA