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The map label for this gene is yugH [H]

Identifier: 78188769

GI number: 78188769

Start: 1119712

End: 1120875

Strand: Reverse

Name: yugH [H]

Synonym: Cag_0798

Alternate gene names: 78188769

Gene position: 1120875-1119712 (Counterclockwise)

Preceding gene: 78188770

Following gene: 78188766

Centisome position: 43.58

GC content: 47.85

Gene sequence:

>1164_bases
ATGAGCTTGCACCTTAGTAATCGCCACGCCTCAGTGCTGCAATCCGAAATTCGTAGCATGTCCATAGCATGTAGTCGTGT
TAACGGCATTAATCTCGCTCAAGGTGTTTGCGATACTCCCGTGCCCAACGAGGTGCTGCAAGGTGCAAGCGAAGCTCTTC
AGCAAGGGGTGAACACTTATACCCATTATGCAGGAATTATTAGTTTACGCGAAGCTATTGCCGATAAGCAAGAACGTTTT
TATGGTATTCGCTACCAGCCTGAATCAGAAATTATTGTAAGTGCCGGTGCAACTGGTGCGCTATACGCAGCTTTTCAAGC
ATTACTGAATCCGGGCGATGAGGTAATTTTATTTGAACCCTTTTATGGTTACCACATAACCACCTTGCAAGCGGCGGAAG
CGGTGCCTCTCTATCTACCGTTAACGCTGCCGGAATGGAGCTTTAGTGAGCACGATCTTGAACAACTTGTTACACCACGT
ACACGAGCCATTATTGTTAATACGCCTGCAAATCCCTCAGGAAAAGTCTTTTCATTAGCAGAAATGGAGCGTATTGCAGC
CTTTGCCGAGCGTTACGACCTATTTGTTTTTACGGATGAAATTTATGAACACTTTCTCTACGAAGGGCATCAACACCATA
GTTTTGCCGCATTGCCCGGCATGAAAGAGCGCACCATAACGGTGTCGGGGGCTTCAAAAACCTTTAGCGTTACGGGATGG
CGTATTGGATATGCCTTGTGCGACGCGCGTTGGGCGCAAGCTATCGGTTACTTTAATGACCTTGTCTATGTTTGTGCGCC
AGCACCATTGCAAGCAGGGGTTGCGCGTGGTATGAGAGAACTTGATGATCGTTTTTACAACCATCTGTCGGTTGATTATC
AAGCAAAGCGCGATCGCTTTTGTGCAACTTTAGCAAAAGCAGGGCTTGTTCCACACATTCCCGATGGTGCCTATTATGTG
TTAGCCGACGTTTCAGCATTACCCGGCAATAGTGCTCACGAGCGAGCCATGCACATTCTTAATCGCACAGGCGTGGCAAG
CGTCCCGGGCAGCGCATTTTATCAACATGGTAGAGGCGATGGGTTAGTTCGTTTTTGCTACGCCAAAGAGGATGCAATTT
TAGAAGAGGCGTACCAACGTCTTGAGCGGTTGAGAGAGGGGTAA

Upstream 100 bases:

>100_bases
GCTTGATATCTTTAAAAAAGAAGCGGCACAAGCAAAAGCAATCCGTTTTTAATGGTACCAAAAACCAGTAAACCGCAACA
TTTTCAATTTTACGTTCACC

Downstream 100 bases:

>100_bases
TTTTGTATTGATGAAAGTGATACCCCATGGTTATTGCTAATAAATTGATTGTTGTATAATATATATTATGTAAACTTAAC
ATTAAACGAACTATCACCCC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSLHLSNRHASVLQSEIRSMSIACSRVNGINLAQGVCDTPVPNEVLQGASEALQQGVNTYTHYAGIISLREAIADKQERF
YGIRYQPESEIIVSAGATGALYAAFQALLNPGDEVILFEPFYGYHITTLQAAEAVPLYLPLTLPEWSFSEHDLEQLVTPR
TRAIIVNTPANPSGKVFSLAEMERIAAFAERYDLFVFTDEIYEHFLYEGHQHHSFAALPGMKERTITVSGASKTFSVTGW
RIGYALCDARWAQAIGYFNDLVYVCAPAPLQAGVARGMRELDDRFYNHLSVDYQAKRDRFCATLAKAGLVPHIPDGAYYV
LADVSALPGNSAHERAMHILNRTGVASVPGSAFYQHGRGDGLVRFCYAKEDAILEEAYQRLERLREG

Sequences:

>Translated_387_residues
MSLHLSNRHASVLQSEIRSMSIACSRVNGINLAQGVCDTPVPNEVLQGASEALQQGVNTYTHYAGIISLREAIADKQERF
YGIRYQPESEIIVSAGATGALYAAFQALLNPGDEVILFEPFYGYHITTLQAAEAVPLYLPLTLPEWSFSEHDLEQLVTPR
TRAIIVNTPANPSGKVFSLAEMERIAAFAERYDLFVFTDEIYEHFLYEGHQHHSFAALPGMKERTITVSGASKTFSVTGW
RIGYALCDARWAQAIGYFNDLVYVCAPAPLQAGVARGMRELDDRFYNHLSVDYQAKRDRFCATLAKAGLVPHIPDGAYYV
LADVSALPGNSAHERAMHILNRTGVASVPGSAFYQHGRGDGLVRFCYAKEDAILEEAYQRLERLREG
>Mature_386_residues
SLHLSNRHASVLQSEIRSMSIACSRVNGINLAQGVCDTPVPNEVLQGASEALQQGVNTYTHYAGIISLREAIADKQERFY
GIRYQPESEIIVSAGATGALYAAFQALLNPGDEVILFEPFYGYHITTLQAAEAVPLYLPLTLPEWSFSEHDLEQLVTPRT
RAIIVNTPANPSGKVFSLAEMERIAAFAERYDLFVFTDEIYEHFLYEGHQHHSFAALPGMKERTITVSGASKTFSVTGWR
IGYALCDARWAQAIGYFNDLVYVCAPAPLQAGVARGMRELDDRFYNHLSVDYQAKRDRFCATLAKAGLVPHIPDGAYYVL
ADVSALPGNSAHERAMHILNRTGVASVPGSAFYQHGRGDGLVRFCYAKEDAILEEAYQRLERLREG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=378, Percent_Identity=33.8624338624339, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI56713256, Length=378, Percent_Identity=33.8624338624339, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI95147551, Length=393, Percent_Identity=32.3155216284987, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI169881279, Length=393, Percent_Identity=32.3155216284987, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=31.1258278145695, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI4507369, Length=299, Percent_Identity=27.4247491638796, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI149944424, Length=240, Percent_Identity=25.8333333333333, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786816, Length=365, Percent_Identity=33.1506849315069, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1788722, Length=342, Percent_Identity=27.4853801169591, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788627, Length=324, Percent_Identity=29.9382716049383, Blast_Score=114, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=413, Percent_Identity=29.7820823244552, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI71994476, Length=413, Percent_Identity=29.7820823244552, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17567369, Length=387, Percent_Identity=29.7157622739018, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17567663, Length=329, Percent_Identity=24.9240121580547, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6322401, Length=388, Percent_Identity=29.8969072164948, Blast_Score=175, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6320317, Length=352, Percent_Identity=23.5795454545455, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=32.9896907216495, Blast_Score=214, Evalue=6e-56,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=32.9896907216495, Blast_Score=214, Evalue=6e-56,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=32.9896907216495, Blast_Score=214, Evalue=6e-56,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=32.9896907216495, Blast_Score=214, Evalue=6e-56,
Organism=Drosophila melanogaster, GI18859735, Length=358, Percent_Identity=25.9776536312849, Blast_Score=105, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42875; Mature: 42744

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHLSNRHASVLQSEIRSMSIACSRVNGINLAQGVCDTPVPNEVLQGASEALQQGVNTY
CCEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
THYAGIISLREAIADKQERFYGIRYQPESEIIVSAGATGALYAAFQALLNPGDEVILFEP
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECC
FYGYHITTLQAAEAVPLYLPLTLPEWSFSEHDLEQLVTPRTRAIIVNTPANPSGKVFSLA
CCCEEEEEEHHCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCEEEHH
EMERIAAFAERYDLFVFTDEIYEHFLYEGHQHHSFAALPGMKERTITVSGASKTFSVTGW
HHHHHHHHHHHHEEEEEEHHHHHHHHHCCCCCCCEEECCCCCCCEEEEECCCCEEEECCH
RIGYALCDARWAQAIGYFNDLVYVCAPAPLQAGVARGMRELDDRFYNHLSVDYQAKRDRF
HHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
CATLAKAGLVPHIPDGAYYVLADVSALPGNSAHERAMHILNRTGVASVPGSAFYQHGRGD
HHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCC
GLVRFCYAKEDAILEEAYQRLERLREG
CEEEEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLHLSNRHASVLQSEIRSMSIACSRVNGINLAQGVCDTPVPNEVLQGASEALQQGVNTY
CEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
THYAGIISLREAIADKQERFYGIRYQPESEIIVSAGATGALYAAFQALLNPGDEVILFEP
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECC
FYGYHITTLQAAEAVPLYLPLTLPEWSFSEHDLEQLVTPRTRAIIVNTPANPSGKVFSLA
CCCEEEEEEHHCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCEEEHH
EMERIAAFAERYDLFVFTDEIYEHFLYEGHQHHSFAALPGMKERTITVSGASKTFSVTGW
HHHHHHHHHHHHEEEEEEHHHHHHHHHCCCCCCCEEECCCCCCCEEEEECCCCEEEECCH
RIGYALCDARWAQAIGYFNDLVYVCAPAPLQAGVARGMRELDDRFYNHLSVDYQAKRDRF
HHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
CATLAKAGLVPHIPDGAYYVLADVSALPGNSAHERAMHILNRTGVASVPGSAFYQHGRGD
HHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCC
GLVRFCYAKEDAILEEAYQRLERLREG
CEEEEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]