Click here to switch to the map view.

The map label for this gene is gcp

Identifier: 78188092

GI number: 78188092

Start: 123241

End: 124293

Strand: Reverse

Name: gcp

Synonym: Cag_0109

Alternate gene names: 78188092

Gene position: 124293-123241 (Counterclockwise)

Preceding gene: 78188097

Following gene: 78188091

Centisome position: 4.83

GC content: 49.76

Gene sequence:

>1053_bases
ATGATAATACTTGGAATTGAAACCAGTTGCGATGAAACCTCAGCCTCCGTGCTCCATAACGGCGTGGTGCTGTCGAACAT
TGTAAGCTCGCAACATTGCCACACTTCGTTTGGCGGCGTGGTGCCCGAACTTGCTTCTCGCGAACATGAGAGGCTTATTA
CCGCCATTACGGAGACGGCAATAAATGAGGCAAATATACAAAAAGATGCGCTTGATGTTATAGCGGCAACGGCTGGACCG
GGGTTAATTGGGGCAATTATGGTGGGCTTGTGCTTTGCGCAAGGCATGGCGTGCGCCTTAAACATTCCCTTTGTGCCCAT
TAATCATATTGAAGCGCACATCTTTTCCCCCTTTATTAATAGCGGCGCAAACAGCCCGCTTCCCAAAGAGGGCTACATTT
CTCTGACGGTATCGGGTGGGCACACCTTGCTTGCCCTTGTAAAACCCGATCTTTCCTACACGATTGTTGGAAAAACGCTG
GATGATGCCGCTGGTGAGGCGTTTGATAAAACGGGAAAAATGATCGGGCTTCCCTATCCTGCTGGACCCGTTATTGATAA
ACTTGCCGAAAATGGTAATCCCAATTTTTATCACTTCCCTCGCGCCTTAACGTCGCGCTCAAAGAGCCGCAAAAGCTGGG
AAGGCAACCTCGACTTTAGCTTTTCGGGCATGAAAACCTCTGTGCTTACATGGTTGCAGCAGCAAAGCCCAGAGAGCGTT
GCTTCCAACCTCCCCGATATTGCCGCCTCCATTCAAGCAGCTATTGTGGATGTATTAGTAGAAAAAAGCATTGCCGCAGC
TAAGCACTACAACGTAAGCACCATTGCCATTGCAGGCGGCGTTAGTGCTAACCGAGGATTACGCAGCTCCATGCAAGCCG
CCTGCCAGCAACACGGCATTACCCTCTGCCTACCTGAAACCATCTACTCAACCGATAACGCCGCTATGATTGCAAGCATT
GCTGCACTCAAGCTCTCGCATGGTATGGAACCACTGTACCGCTATAACGTGGCACCCTATGCAAGCTTTTTACACAAAGA
CAACTTTTCGTAG

Upstream 100 bases:

>100_bases
GCACCATTAAAAGTCGCCCAATACTTACTGAAACCTTCGGTTTGCTCTTGTTAGGCTGATTATTAGCTTTGCCCATAATT
TTTTGGGAGAAAAAAAGAGA

Downstream 100 bases:

>100_bases
ATGCCATATAAATAACTTATATTCGGGCGCTCTTCTGCTCCGCTACACTAACTTAGCAGGTAGCAGCTCTTGCAATCCAA
TTCTACCCAACATCCCTCAT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MIILGIETSCDETSASVLHNGVVLSNIVSSQHCHTSFGGVVPELASREHERLITAITETAINEANIQKDALDVIAATAGP
GLIGAIMVGLCFAQGMACALNIPFVPINHIEAHIFSPFINSGANSPLPKEGYISLTVSGGHTLLALVKPDLSYTIVGKTL
DDAAGEAFDKTGKMIGLPYPAGPVIDKLAENGNPNFYHFPRALTSRSKSRKSWEGNLDFSFSGMKTSVLTWLQQQSPESV
ASNLPDIAASIQAAIVDVLVEKSIAAAKHYNVSTIAIAGGVSANRGLRSSMQAACQQHGITLCLPETIYSTDNAAMIASI
AALKLSHGMEPLYRYNVAPYASFLHKDNFS

Sequences:

>Translated_350_residues
MIILGIETSCDETSASVLHNGVVLSNIVSSQHCHTSFGGVVPELASREHERLITAITETAINEANIQKDALDVIAATAGP
GLIGAIMVGLCFAQGMACALNIPFVPINHIEAHIFSPFINSGANSPLPKEGYISLTVSGGHTLLALVKPDLSYTIVGKTL
DDAAGEAFDKTGKMIGLPYPAGPVIDKLAENGNPNFYHFPRALTSRSKSRKSWEGNLDFSFSGMKTSVLTWLQQQSPESV
ASNLPDIAASIQAAIVDVLVEKSIAAAKHYNVSTIAIAGGVSANRGLRSSMQAACQQHGITLCLPETIYSTDNAAMIASI
AALKLSHGMEPLYRYNVAPYASFLHKDNFS
>Mature_350_residues
MIILGIETSCDETSASVLHNGVVLSNIVSSQHCHTSFGGVVPELASREHERLITAITETAINEANIQKDALDVIAATAGP
GLIGAIMVGLCFAQGMACALNIPFVPINHIEAHIFSPFINSGANSPLPKEGYISLTVSGGHTLLALVKPDLSYTIVGKTL
DDAAGEAFDKTGKMIGLPYPAGPVIDKLAENGNPNFYHFPRALTSRSKSRKSWEGNLDFSFSGMKTSVLTWLQQQSPESV
ASNLPDIAASIQAAIVDVLVEKSIAAAKHYNVSTIAIAGGVSANRGLRSSMQAACQQHGITLCLPETIYSTDNAAMIASI
AALKLSHGMEPLYRYNVAPYASFLHKDNFS

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=355, Percent_Identity=30.9859154929577, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI8923380, Length=323, Percent_Identity=27.5541795665635, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1789445, Length=330, Percent_Identity=37.2727272727273, Blast_Score=232, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI71995670, Length=336, Percent_Identity=29.1666666666667, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17557464, Length=365, Percent_Identity=24.6575342465753, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320099, Length=368, Percent_Identity=29.6195652173913, Blast_Score=133, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6322891, Length=301, Percent_Identity=25.5813953488372, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20129063, Length=360, Percent_Identity=29.4444444444444, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21357207, Length=342, Percent_Identity=28.3625730994152, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_CHLCH (Q3ANQ6)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_378430.1
- ProteinModelPortal:   Q3ANQ6
- SMR:   Q3ANQ6
- STRING:   Q3ANQ6
- MEROPS:   M22.001
- GeneID:   3747597
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_0109
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PLYGVNH
- ProtClustDB:   PRK09604
- BioCyc:   CCHL340177:CAG_0109-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 37051; Mature: 37051

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILGIETSCDETSASVLHNGVVLSNIVSSQHCHTSFGGVVPELASREHERLITAITETA
CEEEEECCCCCHHHHHHHHCCHHHHHHHHCCCCCCHHCCHHHHHHCHHHHHHHHHHHHHH
INEANIQKDALDVIAATAGPGLIGAIMVGLCFAQGMACALNIPFVPINHIEAHIFSPFIN
HHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCEEECCHHHHHHHHHHHH
SGANSPLPKEGYISLTVSGGHTLLALVKPDLSYTIVGKTLDDAAGEAFDKTGKMIGLPYP
CCCCCCCCCCCEEEEEEECCCEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCEEECCCC
AGPVIDKLAENGNPNFYHFPRALTSRSKSRKSWEGNLDFSFSGMKTSVLTWLQQQSPESV
CCHHHHHHHHCCCCCEEECCHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHCCHHHH
ASNLPDIAASIQAAIVDVLVEKSIAAAKHYNVSTIAIAGGVSANRGLRSSMQAACQQHGI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCC
TLCLPETIYSTDNAAMIASIAALKLSHGMEPLYRYNVAPYASFLHKDNFS
EEEECHHHHCCCCHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MIILGIETSCDETSASVLHNGVVLSNIVSSQHCHTSFGGVVPELASREHERLITAITETA
CEEEEECCCCCHHHHHHHHCCHHHHHHHHCCCCCCHHCCHHHHHHCHHHHHHHHHHHHHH
INEANIQKDALDVIAATAGPGLIGAIMVGLCFAQGMACALNIPFVPINHIEAHIFSPFIN
HHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCEEECCHHHHHHHHHHHH
SGANSPLPKEGYISLTVSGGHTLLALVKPDLSYTIVGKTLDDAAGEAFDKTGKMIGLPYP
CCCCCCCCCCCEEEEEEECCCEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCEEECCCC
AGPVIDKLAENGNPNFYHFPRALTSRSKSRKSWEGNLDFSFSGMKTSVLTWLQQQSPESV
CCHHHHHHHHCCCCCEEECCHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHCCHHHH
ASNLPDIAASIQAAIVDVLVEKSIAAAKHYNVSTIAIAGGVSANRGLRSSMQAACQQHGI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCC
TLCLPETIYSTDNAAMIASIAALKLSHGMEPLYRYNVAPYASFLHKDNFS
EEEECHHHHCCCCHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA