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The map label for this gene is tcyA [H]

Identifier: 78067960

GI number: 78067960

Start: 3659980

End: 3660762

Strand: Reverse

Name: tcyA [H]

Synonym: Bcep18194_A6491

Alternate gene names: 78067960

Gene position: 3660762-3659980 (Counterclockwise)

Preceding gene: 78067961

Following gene: 78067959

Centisome position: 99.1

GC content: 64.75

Gene sequence:

>783_bases
ATGAAATTCCTTCGCTCCATCCTGGTCGTCGCCATGCTGCAGGCCGTTTCGGTCACGAGCGCACTGGCTGCCGACGACCT
GTCGCAGATCAAGTCGTCCGGCGTGTTCCGGGTCGGTACCGAAGGCACATATGCGCCGTTCACGTATCACGACGAAACCG
GCAAGCTGACGGGCTTCGACGTCGACATCGCGACCGCGATCGCGCAGCGCCTCGGCGTGAAGCCGCAGTTCGTCGAAGGC
AAGTGGGACGGGCTGATCGCGGGCCTCGACGTGAACCGCTACGACGCGGTCGTCAACGAAGTGTCGATCACCGACGCGCG
CAAGGCGAAATACGATTTCTCGACGCCGTACATCACGTCGCGCGCGGTGCTGATCGTGCGCGCGGACAACACGACGATCC
GCTCGTTCGACGATCTCAAGGGCAAGAAATCCGCGAACACGCTGACCAGCAATTTCGGCAAGCTCGCGGCGTCGCACGGC
GCGGACGTCGTGCCCGTGCAGGGCTTCAACGAAGCGATCGACCTGCTGAGCTCGGGGCGCGTCGACGCGACGATCAACGA
TTCGCTGTCGTACCTCGATTTCCGCAAGCACAAGCCGGACGCGAAGCTGAAGGTCGCGGCGACCGACACCGGCGGCGCGA
GCGACGCATCGGGCGTGCTGCTGCGCAAGGGCAGCCCCGCGCTGGTGGCCGCGGTCGACAAGGCGCTCGCGGACATCAAG
GCGGACGGTACCTACGCGAAGATCTCGCACAAGTATTTCGGCCGCGACGTGTCGCAGCCGTAA

Upstream 100 bases:

>100_bases
GTTTTTGCCGGGCCTCGACGCGTCGGTAGAATTCGCGGACCTCTCGAACGGCATGCATGTGCCGCGGGAAGATTCCCTCC
AATCATTCGGGGTCCGCACC

Downstream 100 bases:

>100_bases
CGCGAGGCTGAACGATGCCGGCCTGGCTTCACCTGATGGCGGAATCGCTGCGGCCCCTGCTGGTTGCGGGGCTCGTGTTC
ACGGTGCCGCTCACGCTCGC

Product: ABC amino acid transporter, periplasmic ligand binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKFLRSILVVAMLQAVSVTSALAADDLSQIKSSGVFRVGTEGTYAPFTYHDETGKLTGFDVDIATAIAQRLGVKPQFVEG
KWDGLIAGLDVNRYDAVVNEVSITDARKAKYDFSTPYITSRAVLIVRADNTTIRSFDDLKGKKSANTLTSNFGKLAASHG
ADVVPVQGFNEAIDLLSSGRVDATINDSLSYLDFRKHKPDAKLKVAATDTGGASDASGVLLRKGSPALVAAVDKALADIK
ADGTYAKISHKYFGRDVSQP

Sequences:

>Translated_260_residues
MKFLRSILVVAMLQAVSVTSALAADDLSQIKSSGVFRVGTEGTYAPFTYHDETGKLTGFDVDIATAIAQRLGVKPQFVEG
KWDGLIAGLDVNRYDAVVNEVSITDARKAKYDFSTPYITSRAVLIVRADNTTIRSFDDLKGKKSANTLTSNFGKLAASHG
ADVVPVQGFNEAIDLLSSGRVDATINDSLSYLDFRKHKPDAKLKVAATDTGGASDASGVLLRKGSPALVAAVDKALADIK
ADGTYAKISHKYFGRDVSQP
>Mature_260_residues
MKFLRSILVVAMLQAVSVTSALAADDLSQIKSSGVFRVGTEGTYAPFTYHDETGKLTGFDVDIATAIAQRLGVKPQFVEG
KWDGLIAGLDVNRYDAVVNEVSITDARKAKYDFSTPYITSRAVLIVRADNTTIRSFDDLKGKKSANTLTSNFGKLAASHG
ADVVPVQGFNEAIDLLSSGRVDATINDSLSYLDFRKHKPDAKLKVAATDTGGASDASGVLLRKGSPALVAAVDKALADIK
ADGTYAKISHKYFGRDVSQP

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=259, Percent_Identity=39.7683397683398, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1788648, Length=229, Percent_Identity=32.3144104803493, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788649, Length=261, Percent_Identity=31.0344827586207, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787085, Length=253, Percent_Identity=31.6205533596838, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787088, Length=255, Percent_Identity=28.6274509803922, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787031, Length=259, Percent_Identity=29.7297297297297, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 27710; Mature: 27710

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLRSILVVAMLQAVSVTSALAADDLSQIKSSGVFRVGTEGTYAPFTYHDETGKLTGFD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEECCCCCEEECC
VDIATAIAQRLGVKPQFVEGKWDGLIAGLDVNRYDAVVNEVSITDARKAKYDFSTPYITS
HHHHHHHHHHHCCCCEEECCCCCCEEEECCCHHHHHHHHHEECCCCHHCCCCCCCCCCCC
RAVLIVRADNTTIRSFDDLKGKKSANTLTSNFGKLAASHGADVVPVQGFNEAIDLLSSGR
EEEEEEECCCCEECCHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCC
VDATINDSLSYLDFRKHKPDAKLKVAATDTGGASDASGVLLRKGSPALVAAVDKALADIK
CCEEECCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHC
ADGTYAKISHKYFGRDVSQP
CCCCEEEEHHHHHCCCCCCC
>Mature Secondary Structure
MKFLRSILVVAMLQAVSVTSALAADDLSQIKSSGVFRVGTEGTYAPFTYHDETGKLTGFD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEECCCCCEEECC
VDIATAIAQRLGVKPQFVEGKWDGLIAGLDVNRYDAVVNEVSITDARKAKYDFSTPYITS
HHHHHHHHHHHCCCCEEECCCCCCEEEECCCHHHHHHHHHEECCCCHHCCCCCCCCCCCC
RAVLIVRADNTTIRSFDDLKGKKSANTLTSNFGKLAASHGADVVPVQGFNEAIDLLSSGR
EEEEEEECCCCEECCHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCC
VDATINDSLSYLDFRKHKPDAKLKVAATDTGGASDASGVLLRKGSPALVAAVDKALADIK
CCEEECCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHC
ADGTYAKISHKYFGRDVSQP
CCCCEEEEHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]