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The map label for this gene is rhtC [H]

Identifier: 78067869

GI number: 78067869

Start: 3568553

End: 3569200

Strand: Direct

Name: rhtC [H]

Synonym: Bcep18194_A6400

Alternate gene names: 78067869

Gene position: 3568553-3569200 (Clockwise)

Preceding gene: 78067868

Following gene: 78067870

Centisome position: 96.6

GC content: 70.83

Gene sequence:

>648_bases
ATGACCTACCTGCCGATCCTGCTGCAAATCGCCGTCGTCTATCTCGTCGCGGCGATCACCCCCGGCCCGAATTTCTTCAT
GATTTCGCAACTGTCGCTCGCGGGCAGGCGCAGCCTCGGTGCCGCGTCGGCGCTCGGCGTCGGCACCGCGTCGATCGCGT
GGGCGACGCTCGCGATGCTCGGCCTCGCGGCCGTGCTGCACCAGGTCGAATGGCTGTACGAGGCGATCCGGATCGGCGGT
GCCGTGTACCTCGTGTATTTCGGCTTCAAGCTGCTGCGGGCGGGCGTGCGCCGCGACACGGCGCCGGCCGACGCGCCCGA
CGAACGTGCGCCGCTGGCCGCGCCGCACGCGCGCGACTACCTGCGCGCGTATCGCAGCGGCCTGTTCACCTGCCTGACGA
ACCCGAAATCGTGCGCGTTCTGGACCAGCGTGTTCGCGGCGATGCTGCCCGCGCACGTGCCGCTGTGGTTCAACGGCGCG
GTGCTGGTGACGATCGGCGTGCTGTCGGCCGGCTGGTATTCGTGCGTCGCGTACCTGTTCGCGAGCCCGCGCGCGCAACG
CGGCTATCGGCGCGTGCGACGCCCGCTCGACGCACTGTGCGGCGTGGCGCTCGTCGGCCTCGGCGCGAAACTCGCGGCCG
AGCGCTGA

Upstream 100 bases:

>100_bases
ATATCAACCGGATTGCGCGCCGCCAAAGCGCGGCCGCGCGGCGCGCGCTACATTAACGCCTTGCCCATTCCGCTCCGCCC
CGCCGCCGGGCCGCGCCGCC

Downstream 100 bases:

>100_bases
AAAACTGAAAGCTTATTGAAATAATTCGTTGCGCCAAATCCGCGCGGCCACGGGGGTCAAGCCCGCGATCCGCGTCAACA
GGGTAAAATAACGAGTTCCT

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MTYLPILLQIAVVYLVAAITPGPNFFMISQLSLAGRRSLGAASALGVGTASIAWATLAMLGLAAVLHQVEWLYEAIRIGG
AVYLVYFGFKLLRAGVRRDTAPADAPDERAPLAAPHARDYLRAYRSGLFTCLTNPKSCAFWTSVFAAMLPAHVPLWFNGA
VLVTIGVLSAGWYSCVAYLFASPRAQRGYRRVRRPLDALCGVALVGLGAKLAAER

Sequences:

>Translated_215_residues
MTYLPILLQIAVVYLVAAITPGPNFFMISQLSLAGRRSLGAASALGVGTASIAWATLAMLGLAAVLHQVEWLYEAIRIGG
AVYLVYFGFKLLRAGVRRDTAPADAPDERAPLAAPHARDYLRAYRSGLFTCLTNPKSCAFWTSVFAAMLPAHVPLWFNGA
VLVTIGVLSAGWYSCVAYLFASPRAQRGYRRVRRPLDALCGVALVGLGAKLAAER
>Mature_214_residues
TYLPILLQIAVVYLVAAITPGPNFFMISQLSLAGRRSLGAASALGVGTASIAWATLAMLGLAAVLHQVEWLYEAIRIGGA
VYLVYFGFKLLRAGVRRDTAPADAPDERAPLAAPHARDYLRAYRSGLFTCLTNPKSCAFWTSVFAAMLPAHVPLWFNGAV
LVTIGVLSAGWYSCVAYLFASPRAQRGYRRVRRPLDALCGVALVGLGAKLAAER

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=212, Percent_Identity=32.0754716981132, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786522, Length=197, Percent_Identity=29.9492385786802, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788099, Length=208, Percent_Identity=26.4423076923077, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23086; Mature: 22955

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYLPILLQIAVVYLVAAITPGPNFFMISQLSLAGRRSLGAASALGVGTASIAWATLAML
CCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHH
GLAAVLHQVEWLYEAIRIGGAVYLVYFGFKLLRAGVRRDTAPADAPDERAPLAAPHARDY
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
LRAYRSGLFTCLTNPKSCAFWTSVFAAMLPAHVPLWFNGAVLVTIGVLSAGWYSCVAYLF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHH
ASPRAQRGYRRVRRPLDALCGVALVGLGAKLAAER
HCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure 
TYLPILLQIAVVYLVAAITPGPNFFMISQLSLAGRRSLGAASALGVGTASIAWATLAML
CHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHH
GLAAVLHQVEWLYEAIRIGGAVYLVYFGFKLLRAGVRRDTAPADAPDERAPLAAPHARDY
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
LRAYRSGLFTCLTNPKSCAFWTSVFAAMLPAHVPLWFNGAVLVTIGVLSAGWYSCVAYLF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHH
ASPRAQRGYRRVRRPLDALCGVALVGLGAKLAAER
HCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]