Click here to switch to the map view.

The map label for this gene is dppA [H]

Identifier: 78067861

GI number: 78067861

Start: 3559783

End: 3561411

Strand: Reverse

Name: dppA [H]

Synonym: Bcep18194_A6392

Alternate gene names: 78067861

Gene position: 3561411-3559783 (Counterclockwise)

Preceding gene: 78067862

Following gene: 78067860

Centisome position: 96.41

GC content: 62.49

Gene sequence:

>1629_bases
ATGGAATACAACCGTCTGTTGCACACCCTGCGTGTTACCGCCATTGCAGGCGTGGCAGCGGCATCGCTCGGCGTCGCGGG
TTCTGCATTCGCACAGATCCCGAACAAAACGCTCGTCTACTGCTCAGAAGGCAGCCCGGCGGGTTTCGATTCCGCGCAGT
TTACGACCGGCGTCGATTTCACCGCCGCCACGTTCACCGTCTACAACCGCCTCGTCGAATTCGAGCGCGGCGGCACGAAG
GTCGAGCCGGGCCTCGCCGAGAAATGGGACGTGTCGCCGGACGGCAAGGTGTACACGTTCCACCTGCGCCATGGTGTGAA
GTTCCACACGACCGACTTCTTCAAGCCGACGCGTGAATTCAACGCGGACGACGTGCTGTTCACGTTCCAGCGCATGCTCG
ACCCGAACCAGGCGTTCCGCAAGGCGTACCCGGTGTCGTTCCCGTACTTCACCGACATGGGCCTCGACAAGCTGATCACG
AAGGTCGAGAAGGTCGATCCGTACACCGTGAAGTTCACGCTCGCCGAGCCGAATGCGCCGTTCATCCAGAACATGGCGAT
GGAATTCGCGTCGATCCTGTCGGCCGAATACGGCGACCAGCTGATGAAGGCAGGCAAGGCCGCCGACATCAACCAGAAGC
CGGTCGGCACGGGCCCGTTCATCTTCCGCAGCTACACGAAGGATGCGACGATCCGGTTCGACGGCAATCCTGATTACTGG
AAGAAGGGCGAAGTGAAGCTCTCGAAGCTGATCTTCTCGATCACGCCCGATCCGGGCGTGCGCGTGCAGAAGGTCAAGCG
CAACGAATGCCAGGTGATGAGCTATCCGCGTCCGGCCGACATCGCGACGCTGAAGGCAGATCCGAACGTCGACATGCCGT
CGCAGGCAGGCTTCAACCTCGGCTACCTCGCGTACAACGTCGAGCACAAGCCGGTCGACAAGCTCGAGGTGCGTCAGGCA
CTCGACATGGCGATCAACAAGAAGGCGATCCTCGAGTCCGTCTACCAGGGTGCCGGCCAGGCTGCTACCGCGCCGATGCC
GCCGACCCAATGGTCGTACGACAAGAACCTGAAGATGGCGCCGAACGACACCGCGAAGGCGAAGGCGCTGCTCGCGAAGG
CCGGCTTCCCGAACGGTTTCGAGATCACGCTGTGGGCGATGCCGGTGCAGCGCGCGTACAACCCGAACGCCCGCCTGATG
GCCGAGATGATCCAGGCCGACTGGGCGAAGATCGGCGTGAAGGCGAAGATCGTCACGTATGAATGGGGCGAGTACATCAA
GCGCGCGCACGCGGGCGAGCAGGACACGATGCTGATCGGCTGGACGGGCGACAACGGCGATCCGGACAACTGGCTCGGCA
CGCTGCTCGGCTGCGACGCGATCAAGGGCAACAACTTTTCGCACTGGTGCTACAAGCCGTTCGACGATCTGGTCCAGAAG
GGCCGCACGACGACGGGCCAGGACGCGCGGACGAAGCTCTACACGCAGGCTCAGCAGATCTTCGCGCAACAGCTGCCGTT
CTCGCCGATCGCGAACTCGACGGTCTACCAGCCGGTGCGCAAGACCGTGGTCGACATGCGTATCGAGCCGCTCGGCTATG
CCCGCTTCGACGGTGTTAGCGTGAAGTAA

Upstream 100 bases:

>100_bases
GAGTTTTTTCTCCAGCTTGTTGCCACATCGTTAGCTCAAGTAATATCCGCGTACACCGGCCCCGGGCGGGCCGGTTCCGA
TCTGGAGACCTGGAGGAAAC

Downstream 100 bases:

>100_bases
CACGCCCGGCGTAAGCTGTCTACGAAGACCGAGACCGGCTAATTCATCCGGCGGCGGGAGGCCAAAAGCTTCCCGTCGCC
GGTCGCACATTTCCCACAAG

Product: ABC oligopeptide transporter, periplasmic ligand binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MEYNRLLHTLRVTAIAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDFTAATFTVYNRLVEFERGGTK
VEPGLAEKWDVSPDGKVYTFHLRHGVKFHTTDFFKPTREFNADDVLFTFQRMLDPNQAFRKAYPVSFPYFTDMGLDKLIT
KVEKVDPYTVKFTLAEPNAPFIQNMAMEFASILSAEYGDQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
KKGEVKLSKLIFSITPDPGVRVQKVKRNECQVMSYPRPADIATLKADPNVDMPSQAGFNLGYLAYNVEHKPVDKLEVRQA
LDMAINKKAILESVYQGAGQAATAPMPPTQWSYDKNLKMAPNDTAKAKALLAKAGFPNGFEITLWAMPVQRAYNPNARLM
AEMIQADWAKIGVKAKIVTYEWGEYIKRAHAGEQDTMLIGWTGDNGDPDNWLGTLLGCDAIKGNNFSHWCYKPFDDLVQK
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKTVVDMRIEPLGYARFDGVSVK

Sequences:

>Translated_542_residues
MEYNRLLHTLRVTAIAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDFTAATFTVYNRLVEFERGGTK
VEPGLAEKWDVSPDGKVYTFHLRHGVKFHTTDFFKPTREFNADDVLFTFQRMLDPNQAFRKAYPVSFPYFTDMGLDKLIT
KVEKVDPYTVKFTLAEPNAPFIQNMAMEFASILSAEYGDQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
KKGEVKLSKLIFSITPDPGVRVQKVKRNECQVMSYPRPADIATLKADPNVDMPSQAGFNLGYLAYNVEHKPVDKLEVRQA
LDMAINKKAILESVYQGAGQAATAPMPPTQWSYDKNLKMAPNDTAKAKALLAKAGFPNGFEITLWAMPVQRAYNPNARLM
AEMIQADWAKIGVKAKIVTYEWGEYIKRAHAGEQDTMLIGWTGDNGDPDNWLGTLLGCDAIKGNNFSHWCYKPFDDLVQK
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKTVVDMRIEPLGYARFDGVSVK
>Mature_542_residues
MEYNRLLHTLRVTAIAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDFTAATFTVYNRLVEFERGGTK
VEPGLAEKWDVSPDGKVYTFHLRHGVKFHTTDFFKPTREFNADDVLFTFQRMLDPNQAFRKAYPVSFPYFTDMGLDKLIT
KVEKVDPYTVKFTLAEPNAPFIQNMAMEFASILSAEYGDQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
KKGEVKLSKLIFSITPDPGVRVQKVKRNECQVMSYPRPADIATLKADPNVDMPSQAGFNLGYLAYNVEHKPVDKLEVRQA
LDMAINKKAILESVYQGAGQAATAPMPPTQWSYDKNLKMAPNDTAKAKALLAKAGFPNGFEITLWAMPVQRAYNPNARLM
AEMIQADWAKIGVKAKIVTYEWGEYIKRAHAGEQDTMLIGWTGDNGDPDNWLGTLLGCDAIKGNNFSHWCYKPFDDLVQK
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKTVVDMRIEPLGYARFDGVSVK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=519, Percent_Identity=54.3352601156069, Blast_Score=588, Evalue=1e-169,
Organism=Escherichia coli, GI1787551, Length=533, Percent_Identity=34.7091932457786, Blast_Score=331, Evalue=7e-92,
Organism=Escherichia coli, GI1787052, Length=459, Percent_Identity=28.9760348583878, Blast_Score=175, Evalue=7e-45,
Organism=Escherichia coli, GI1787762, Length=502, Percent_Identity=25.8964143426295, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789887, Length=464, Percent_Identity=27.1551724137931, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787495, Length=537, Percent_Identity=23.463687150838, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87081878, Length=563, Percent_Identity=24.3339253996448, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789397, Length=508, Percent_Identity=23.8188976377953, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60340; Mature: 60340

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYNRLLHTLRVTAIAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDF
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCH
TAATFTVYNRLVEFERGGTKVEPGLAEKWDVSPDGKVYTFHLRHGVKFHTTDFFKPTREF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCHHHC
NADDVLFTFQRMLDPNQAFRKAYPVSFPYFTDMGLDKLITKVEKVDPYTVKFTLAEPNAP
CCCHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHCCCEEEEEEEECCCCH
FIQNMAMEFASILSAEYGDQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCC
KKGEVKLSKLIFSITPDPGVRVQKVKRNECQVMSYPRPADIATLKADPNVDMPSQAGFNL
CCCCEEEEEEEEEECCCCCCEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCE
GYLAYNVEHKPVDKLEVRQALDMAINKKAILESVYQGAGQAATAPMPPTQWSYDKNLKMA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEC
PNDTAKAKALLAKAGFPNGFEITLWAMPVQRAYNPNARLMAEMIQADWAKIGVKAKIVTY
CCCHHHHHHHHHHCCCCCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEEE
EWGEYIKRAHAGEQDTMLIGWTGDNGDPDNWLGTLLGCDAIKGNNFSHWCYKPFDDLVQK
HHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHC
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKTVVDMRIEPLGYARFDGVS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCC
VK
CC
>Mature Secondary Structure
MEYNRLLHTLRVTAIAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDF
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCH
TAATFTVYNRLVEFERGGTKVEPGLAEKWDVSPDGKVYTFHLRHGVKFHTTDFFKPTREF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCHHHC
NADDVLFTFQRMLDPNQAFRKAYPVSFPYFTDMGLDKLITKVEKVDPYTVKFTLAEPNAP
CCCHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHCCCEEEEEEEECCCCH
FIQNMAMEFASILSAEYGDQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCC
KKGEVKLSKLIFSITPDPGVRVQKVKRNECQVMSYPRPADIATLKADPNVDMPSQAGFNL
CCCCEEEEEEEEEECCCCCCEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCE
GYLAYNVEHKPVDKLEVRQALDMAINKKAILESVYQGAGQAATAPMPPTQWSYDKNLKMA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEC
PNDTAKAKALLAKAGFPNGFEITLWAMPVQRAYNPNARLMAEMIQADWAKIGVKAKIVTY
CCCHHHHHHHHHHCCCCCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEEE
EWGEYIKRAHAGEQDTMLIGWTGDNGDPDNWLGTLLGCDAIKGNNFSHWCYKPFDDLVQK
HHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHC
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKTVVDMRIEPLGYARFDGVS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]