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The map label for this gene is ywqM [H]

Identifier: 78067748

GI number: 78067748

Start: 3441151

End: 3442068

Strand: Reverse

Name: ywqM [H]

Synonym: Bcep18194_A6279

Alternate gene names: 78067748

Gene position: 3442068-3441151 (Counterclockwise)

Preceding gene: 78067755

Following gene: 78067737

Centisome position: 93.18

GC content: 67.43

Gene sequence:

>918_bases
ATGGCCCTGACCCTCAGACAGCTCAAGTATTTCGTCGCGACCGCCGAGCTCGGCCAGATCTCGCAGGCCGCGATCCAGCT
CACGATTTCGCAGTCGGCCGTGACGAGCGCGATCAAGGAACTGGAGGACAGCCTCGGCACGCAGCTCTTTCTGCGCACGC
CGTCGGGCGTGACGCTCACCGACACGGGGCGGCGCTTCCTGAATCACGCGTACACGATCCTGTCGTCGGTCGACGAGGCG
ATGCGGATCCCGAACCTCGAAAGCACGCTGACCGGCACGCTCGCGATCGCCGCGAGCTACACGGTGCTCGGCTACTTCCT
GCCGCACCACGTGCTGCGCCTGAACACGCTGTACCCGCGGCTGACGATCCACCTGCACGAGCTGAACCGCGAGTCGATCG
AGGAAGGGCTGATCGCGGGCCGCTACGACATGGCCGTGCTGCTCACGTCGAACGTGTCGAATCCGGCGCTCGTGCTGGAG
CCGGTGATCCATTCGGTGCGGCGGCTGTGGGTCGGTGCGCATCACCCGCTGCTCAGGCACGAGAGCGTCACGTTCGCGGA
AGTCGCGCGCGAGCCGTTCGTGATGCTGACGGTCGACGAGGCCGGGCAGACGGCGCTGCGCTACTGGAACGAGACGCCGT
ACCGGCCGAACGTGATCCTGCGCACGTCGTCCGTCGAGGCGGTGCGCAGCATGGTCGCGAACGGCAGCGGTGTCGCGATC
CTGTCCGACATGGTGTACCGCCCGTGGTCGCTCGAGGGCCGGCGGATCGAGACGATCGTGCTGCGCGACCCGGTGCCGCC
GATGAGTGTAGGTCTCGCCTGGCGCAAGGACATCGAGTTGAGCCCCGCGATGCACGCGGTGCGCGACTATTTCCGGCACA
CGTTCATGGAGCCGCGCGCGTTGGGCGTGGCGGGCTGA

Upstream 100 bases:

>100_bases
CGTTGCAGCAGGGGTGGCAGGGTTTCCACGCAGTCAGGTTGATGGGCGCCGCCCGGTTGTTATGATGTTTATCGCGTGCC
CATCTGTTTTCTCATCGACC

Downstream 100 bases:

>100_bases
GTGCGCGGCGCACACGTAAAAAAAGCCGGGACGTATCCCGGCTTTTTCATGCGGCGAACGAATCCGCCGTGCGTGGCGCT
TACGCGTTCGCCGACATCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDSLGTQLFLRTPSGVTLTDTGRRFLNHAYTILSSVDEA
MRIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPRLTIHLHELNRESIEEGLIAGRYDMAVLLTSNVSNPALVLE
PVIHSVRRLWVGAHHPLLRHESVTFAEVAREPFVMLTVDEAGQTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAI
LSDMVYRPWSLEGRRIETIVLRDPVPPMSVGLAWRKDIELSPAMHAVRDYFRHTFMEPRALGVAG

Sequences:

>Translated_305_residues
MALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDSLGTQLFLRTPSGVTLTDTGRRFLNHAYTILSSVDEA
MRIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPRLTIHLHELNRESIEEGLIAGRYDMAVLLTSNVSNPALVLE
PVIHSVRRLWVGAHHPLLRHESVTFAEVAREPFVMLTVDEAGQTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAI
LSDMVYRPWSLEGRRIETIVLRDPVPPMSVGLAWRKDIELSPAMHAVRDYFRHTFMEPRALGVAG
>Mature_304_residues
ALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDSLGTQLFLRTPSGVTLTDTGRRFLNHAYTILSSVDEAM
RIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPRLTIHLHELNRESIEEGLIAGRYDMAVLLTSNVSNPALVLEP
VIHSVRRLWVGAHHPLLRHESVTFAEVAREPFVMLTVDEAGQTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAIL
SDMVYRPWSLEGRRIETIVLRDPVPPMSVGLAWRKDIELSPAMHAVRDYFRHTFMEPRALGVAG

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=280, Percent_Identity=30, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI157672245, Length=229, Percent_Identity=30.5676855895196, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=28.3737024221453, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787530, Length=251, Percent_Identity=28.2868525896414, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787879, Length=305, Percent_Identity=32.1311475409836, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=27.4576271186441, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788297, Length=259, Percent_Identity=29.3436293436293, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788887, Length=299, Percent_Identity=26.4214046822742, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788748, Length=166, Percent_Identity=28.3132530120482, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=31.0344827586207, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786401, Length=305, Percent_Identity=25.9016393442623, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87081904, Length=196, Percent_Identity=30.1020408163265, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=25, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082132, Length=303, Percent_Identity=23.7623762376238, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789506, Length=278, Percent_Identity=22.6618705035971, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787806, Length=145, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790208, Length=285, Percent_Identity=27.3684210526316, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33993; Mature: 33862

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDSLGTQLFLRTPSGVTLT
CCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHCCCEEEEECCCCCEEE
DTGRRFLNHAYTILSSVDEAMRIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
LTIHLHELNRESIEEGLIAGRYDMAVLLTSNVSNPALVLEPVIHSVRRLWVGAHHPLLRH
EEEEEECCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHC
ESVTFAEVAREPFVMLTVDEAGQTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAI
CCCHHHHHHHCCEEEEEECCCCCHHHHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCCEE
LSDMVYRPWSLEGRRIETIVLRDPVPPMSVGLAWRKDIELSPAMHAVRDYFRHTFMEPRA
EHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCC
LGVAG
CCCCC
>Mature Secondary Structure 
ALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDSLGTQLFLRTPSGVTLT
CCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHCCCEEEEECCCCCEEE
DTGRRFLNHAYTILSSVDEAMRIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
LTIHLHELNRESIEEGLIAGRYDMAVLLTSNVSNPALVLEPVIHSVRRLWVGAHHPLLRH
EEEEEECCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHC
ESVTFAEVAREPFVMLTVDEAGQTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAI
CCCHHHHHHHCCEEEEEECCCCCHHHHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCCEE
LSDMVYRPWSLEGRRIETIVLRDPVPPMSVGLAWRKDIELSPAMHAVRDYFRHTFMEPRA
EHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCC
LGVAG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]