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The map label for this gene is gylR [H]

Identifier: 78067725

GI number: 78067725

Start: 3413660

End: 3414526

Strand: Direct

Name: gylR [H]

Synonym: Bcep18194_A6256

Alternate gene names: 78067725

Gene position: 3413660-3414526 (Clockwise)

Preceding gene: 78067718

Following gene: 78067726

Centisome position: 92.41

GC content: 70.93

Gene sequence:

>867_bases
ATGCCTGCCAGCCCGCTTCCCGACGACGATCTCGCCGACTCCGACACCGACGACGCCGCTTCCGGCGAGCACGGCGAGAA
GGTCCGTTCCGGCATCCAGTCGATCGAGGTCGGCTTCCGCCTGCTCGACGTGCTGACGAGCGAGCCGCGCGCGATGATGC
TGCGCGACCTCGCGCAGCGCGCGGGCATGAGTCCTGCGAAGGCGCACCGCTACCTGGTCAGCTTCTCGCGGCTCGGCGTG
GTGTCGCAGGATCCCGTCTCGGGCCGCTACGAGCTCGGCGGCTTCGCGCTGCAGATGGGGCTTGCGCGGCTCGCGCGCGT
CGACGGCGTGAAGCTCGCGCGGATCGCGCTGACCGAATTCCGCGACCGCCTCGACCAGACGGTCGGCATCGCCGTGTGGG
GCAACCAGGGGCCGACGATCGTCCACTGGATGGAATCGAGCCACCCGGCGAAGGCGTCGCTGAAGCTCGGCGACGTGATG
CCGCTGCTCGGCTCCGCGACGGGGCTGCTGTTCGCCGCGTACCTGCCGCGCAGCAAGACCGCCGCGATGCTCGAGCGCGA
ACTCGCCGATACGCGCCGCTCGCCGCACCACGGCGGCCCGCGCACGCTCGACGAGGTCGACGCGGTGCTCGCCGACGTGC
GCCGGCACGAGGCCGCGCGCGTCGAGGGGATGCTGCTGCCGACGATCCACGCGTTCTGCATGCCCGTGTTCGATGCGGTC
GGCGAACTCGCGCTCGCGATCGTCGCGCTCGGCCAGGAAGGCTCGTTCGACATTGCATGGGGCGGCGAGATCGACACCGC
GCTGCGCGCATGCGCGCAGAAACTGTCTTACGAACTCGGCTATAGTCCCGACGCGCGCGACGCCTGA

Upstream 100 bases:

>100_bases
TCCCTGCGGCGCGCCGCGATTGTGCGCGCCGTTTTCGCCCCGATTTTTCGGCCCGGTTTTTCAGCCCGACTTCTACCGCC
TTTTCGCGCACCTGCCGCCC

Downstream 100 bases:

>100_bases
CGCATCCGGTACCCACCCCGTCACGCAGCGCGAACGCGCGGCGCATTCGACAGTCCGATTCCTGTGGCGCGCGCGGCGCG
CCCGACGTCATGCGAACGCC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MPASPLPDDDLADSDTDDAASGEHGEKVRSGIQSIEVGFRLLDVLTSEPRAMMLRDLAQRAGMSPAKAHRYLVSFSRLGV
VSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTEFRDRLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVM
PLLGSATGLLFAAYLPRSKTAAMLERELADTRRSPHHGGPRTLDEVDAVLADVRRHEAARVEGMLLPTIHAFCMPVFDAV
GELALAIVALGQEGSFDIAWGGEIDTALRACAQKLSYELGYSPDARDA

Sequences:

>Translated_288_residues
MPASPLPDDDLADSDTDDAASGEHGEKVRSGIQSIEVGFRLLDVLTSEPRAMMLRDLAQRAGMSPAKAHRYLVSFSRLGV
VSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTEFRDRLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVM
PLLGSATGLLFAAYLPRSKTAAMLERELADTRRSPHHGGPRTLDEVDAVLADVRRHEAARVEGMLLPTIHAFCMPVFDAV
GELALAIVALGQEGSFDIAWGGEIDTALRACAQKLSYELGYSPDARDA
>Mature_287_residues
PASPLPDDDLADSDTDDAASGEHGEKVRSGIQSIEVGFRLLDVLTSEPRAMMLRDLAQRAGMSPAKAHRYLVSFSRLGVV
SQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTEFRDRLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMP
LLGSATGLLFAAYLPRSKTAAMLERELADTRRSPHHGGPRTLDEVDAVLADVRRHEAARVEGMLLPTIHAFCMPVFDAVG
ELALAIVALGQEGSFDIAWGGEIDTALRACAQKLSYELGYSPDARDA

Specific function: May be an activator protein for the gylABX operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=154, Percent_Identity=25.3246753246753, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788131, Length=237, Percent_Identity=24.0506329113924, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789999, Length=267, Percent_Identity=25.0936329588015, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30984; Mature: 30852

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASPLPDDDLADSDTDDAASGEHGEKVRSGIQSIEVGFRLLDVLTSEPRAMMLRDLAQR
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AGMSPAKAHRYLVSFSRLGVVSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTEF
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RDRLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMPLLGSATGLLFAAYLPRSKT
HHHHHHHEEEEEECCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHH
AAMLERELADTRRSPHHGGPRTLDEVDAVLADVRRHEAARVEGMLLPTIHAFCMPVFDAV
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GELALAIVALGQEGSFDIAWGGEIDTALRACAQKLSYELGYSPDARDA
HHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PASPLPDDDLADSDTDDAASGEHGEKVRSGIQSIEVGFRLLDVLTSEPRAMMLRDLAQR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AGMSPAKAHRYLVSFSRLGVVSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTEF
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RDRLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMPLLGSATGLLFAAYLPRSKT
HHHHHHHEEEEEECCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHH
AAMLERELADTRRSPHHGGPRTLDEVDAVLADVRRHEAARVEGMLLPTIHAFCMPVFDAV
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GELALAIVALGQEGSFDIAWGGEIDTALRACAQKLSYELGYSPDARDA
HHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3225846; 12000953 [H]