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The map label for this gene is lptA [H]

Identifier: 78067588

GI number: 78067588

Start: 3263414

End: 3264079

Strand: Direct

Name: lptA [H]

Synonym: Bcep18194_A6119

Alternate gene names: 78067588

Gene position: 3263414-3264079 (Clockwise)

Preceding gene: 78067587

Following gene: 78067589

Centisome position: 88.34

GC content: 68.17

Gene sequence:

>666_bases
ATGAACGAACCGTTCCCTCGACAGATTTCCGGCGGCGCTGCGCGCGCCGTCCGCGCCGCGCTTGCCGCGACGCTCGTGGC
GCTCCCGCTGGTCGGGCTGGCGCCGCTCGCCCATGCCGAGAAGGCTGACCAGAGCAAGCCGATCAACGTCGAGGCAGACA
ACCTGACCTATGACGACCTGAAGCAGGTCACGGTCGCAACCGGCAACGTCGTGATCACGAAGGGCACGATCATCATCAAG
GGCGATCGCGTCGAAGTGCGCCAGGACCCGGAAGGCTATCAGTACGCCACTTCGTTCGGCAGCGGCAAGAAGCACGCGAC
GTTCCGCCAGAAGCGCGAAGGCCTCGACGAGTACATCGACGGCGACGCCGAGCGCATCGACTACGACGGCAAGCAGGACC
TGACCACGCTGACCACCGCCGCGACCGTGCGCCGCCTGCAGGGCACGACGACCATCGCAGATACCGTGCACGGCAGCGTG
ATCACGTACGACGGCCAGCGCGACTTCTACACCGCGAAGGGCGGCAAGGACGTCGCTGCGCCGGGCAACCCGAACGGCCG
CGTGCGCGCGATGCTGTCGCCGAAGAACGGCGGCCCCGCGCCACTGAACGGCGCGCCGGCAAAGCTGTCGCCGTCGACCA
CGATCCAGGGGGCGCCGGGCCAATGA

Upstream 100 bases:

>100_bases
TCATCGAGCTTTACGGCAACGTGCGCGGCACGATCGCCGCGGCGGGCACGTCCGGCGGCTCGAAAGGTCAACCCAAGTGA
CGCATCCCTCACGTGACTGC

Downstream 100 bases:

>100_bases
ACGCGCTACCGAACCGCCAGCCGGCCGGCACGACGAGCTCGCTCGTCGTCCGCAACCTGAAGAAACGCTACGGCTCGCGC
ACGGTCGTCAAGGACGTGTC

Product: OstA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MNEPFPRQISGGAARAVRAALAATLVALPLVGLAPLAHAEKADQSKPINVEADNLTYDDLKQVTVATGNVVITKGTIIIK
GDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYIDGDAERIDYDGKQDLTTLTTAATVRRLQGTTTIADTVHGSV
ITYDGQRDFYTAKGGKDVAAPGNPNGRVRAMLSPKNGGPAPLNGAPAKLSPSTTIQGAPGQ

Sequences:

>Translated_221_residues
MNEPFPRQISGGAARAVRAALAATLVALPLVGLAPLAHAEKADQSKPINVEADNLTYDDLKQVTVATGNVVITKGTIIIK
GDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYIDGDAERIDYDGKQDLTTLTTAATVRRLQGTTTIADTVHGSV
ITYDGQRDFYTAKGGKDVAAPGNPNGRVRAMLSPKNGGPAPLNGAPAKLSPSTTIQGAPGQ
>Mature_221_residues
MNEPFPRQISGGAARAVRAALAATLVALPLVGLAPLAHAEKADQSKPINVEADNLTYDDLKQVTVATGNVVITKGTIIIK
GDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYIDGDAERIDYDGKQDLTTLTTAATVRRLQGTTTIADTVHGSV
ITYDGQRDFYTAKGGKDVAAPGNPNGRVRAMLSPKNGGPAPLNGAPAKLSPSTTIQGAPGQ

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 23284; Mature: 23284

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEPFPRQISGGAARAVRAALAATLVALPLVGLAPLAHAEKADQSKPINVEADNLTYDDL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHH
KQVTVATGNVVITKGTIIIKGDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYID
HEEEEECCCEEEEECEEEEECCEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHC
GDAERIDYDGKQDLTTLTTAATVRRLQGTTTIADTVHGSVITYDGQRDFYTAKGGKDVAA
CCHHEECCCCCCCHHHHHHHHHHHHHCCCCEEHHHCCCCEEEECCCCCEEECCCCCCCCC
PGNPNGRVRAMLSPKNGGPAPLNGAPAKLSPSTTIQGAPGQ
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCC
>Mature Secondary Structure
MNEPFPRQISGGAARAVRAALAATLVALPLVGLAPLAHAEKADQSKPINVEADNLTYDDL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHH
KQVTVATGNVVITKGTIIIKGDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYID
HEEEEECCCEEEEECEEEEECCEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHC
GDAERIDYDGKQDLTTLTTAATVRRLQGTTTIADTVHGSVITYDGQRDFYTAKGGKDVAA
CCHHEECCCCCCCHHHHHHHHHHHHHCCCCEEHHHCCCCEEEECCCCCEEECCCCCCCCC
PGNPNGRVRAMLSPKNGGPAPLNGAPAKLSPSTTIQGAPGQ
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]