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The map label for this gene is plsC [H]

Identifier: 78067500

GI number: 78067500

Start: 3168299

End: 3169063

Strand: Direct

Name: plsC [H]

Synonym: Bcep18194_A6031

Alternate gene names: 78067500

Gene position: 3168299-3169063 (Clockwise)

Preceding gene: 78067499

Following gene: 78067501

Centisome position: 85.77

GC content: 63.92

Gene sequence:

>765_bases
ATGCGCTTCGTCCGTTCCCTGCTGCTGCTGATCTACTTCATCCTGTACACGGTGCCGTACGCCACCGCGTGCTTCATCGC
CTTTCCGTTCATGCGCTCCGACGCGCGTTACTGGATGGCCGCCGGCTGGTGCAAGTCGACGCTGTGGGTCGTGCGCTGGC
TGAACGGCATCCGCTACCGGATCGAAGGGTACGAGAACCTGCCCGACGGCCCGGCGGTGCTGCTGTCGAAGCACCAGTCC
GCGTGGGAGACGCTCGCGTTTCCGGCGCTGATGCCGAGGCCGCTTTGCTACGTGTTCAAGCGCGAGTTGCTGTACGTGCC
GTTCTTCGGCTGGGCGCTCGGGATGCTGCACATGGTTAACATCAACCGCAAGGAAGGCAAGAACGCGTTCACTTCCGTGA
TCCGCCAGGGCAAGAAGCGCCTGTCGGAAGGCGCATGGATGATCATGTTCCCGGAAGGCACGCGCACGCCGGTCGGCAAG
CAGGGCAAGTACAAGACGGGCGGCGCGCGTTTCGCGATCGAAACCGGCGCACCCGTCGTGCCGATCGCGCACAATGCAGG
TCGGGTGTGGCCGCGCAACTCGTTCACGAAATTCCCGGGCGTCGTCACCGTGTCGATCGGCAAGCCGATCCCCAGCGAAG
GGTTGACGCCCGATGCATTGAACTCGCAGGTCGAAGCATGGATCGAAGCGGAAATGCGCCGGATCGATCCCGATTCGTAT
CGCCAGGCGGGTAATGCCGGCACGCGCGATGCCGCGCGTGTCTGA

Upstream 100 bases:

>100_bases
GTTCACGACGACCTGCGCGCGTTCGCGCTCGATTTCCTTTCACACGAACACGAGTGATGCAGCCGCCGCGCGCATCCTCC
CTAACGCCTGACTTACGCCG

Downstream 100 bases:

>100_bases
CGCCCCCAGGTTGCAGCCGTTGCGTACGACAAAAAGAAGCGAACTGATGAAACAGCGTCCGCGGCCACGGCCTGCCGTCG
TGGCCCTCGATCATCGCCAG

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRSDARYWMAAGWCKSTLWVVRWLNGIRYRIEGYENLPDGPAVLLSKHQS
AWETLAFPALMPRPLCYVFKRELLYVPFFGWALGMLHMVNINRKEGKNAFTSVIRQGKKRLSEGAWMIMFPEGTRTPVGK
QGKYKTGGARFAIETGAPVVPIAHNAGRVWPRNSFTKFPGVVTVSIGKPIPSEGLTPDALNSQVEAWIEAEMRRIDPDSY
RQAGNAGTRDAARV

Sequences:

>Translated_254_residues
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRSDARYWMAAGWCKSTLWVVRWLNGIRYRIEGYENLPDGPAVLLSKHQS
AWETLAFPALMPRPLCYVFKRELLYVPFFGWALGMLHMVNINRKEGKNAFTSVIRQGKKRLSEGAWMIMFPEGTRTPVGK
QGKYKTGGARFAIETGAPVVPIAHNAGRVWPRNSFTKFPGVVTVSIGKPIPSEGLTPDALNSQVEAWIEAEMRRIDPDSY
RQAGNAGTRDAARV
>Mature_254_residues
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRSDARYWMAAGWCKSTLWVVRWLNGIRYRIEGYENLPDGPAVLLSKHQS
AWETLAFPALMPRPLCYVFKRELLYVPFFGWALGMLHMVNINRKEGKNAFTSVIRQGKKRLSEGAWMIMFPEGTRTPVGK
QGKYKTGGARFAIETGAPVVPIAHNAGRVWPRNSFTKFPGVVTVSIGKPIPSEGLTPDALNSQVEAWIEAEMRRIDPDSY
RQAGNAGTRDAARV

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=193, Percent_Identity=29.5336787564767, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI15100175, Length=193, Percent_Identity=29.5336787564767, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI6041665, Length=174, Percent_Identity=28.735632183908, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1789395, Length=117, Percent_Identity=32.4786324786325, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17564032, Length=239, Percent_Identity=26.7782426778243, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320151, Length=206, Percent_Identity=25.7281553398058, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281364648, Length=198, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582856, Length=198, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582854, Length=198, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641614, Length=190, Percent_Identity=25.7894736842105, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641612, Length=190, Percent_Identity=25.7894736842105, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28728; Mature: 28728

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRSDARYWMAAGWCKSTLWVVRWLNGIRYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEE
IEGYENLPDGPAVLLSKHQSAWETLAFPALMPRPLCYVFKRELLYVPFFGWALGMLHMVN
ECCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
INRKEGKNAFTSVIRQGKKRLSEGAWMIMFPEGTRTPVGKQGKYKTGGARFAIETGAPVV
CCHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEE
PIAHNAGRVWPRNSFTKFPGVVTVSIGKPIPSEGLTPDALNSQVEAWIEAEMRRIDPDSY
EEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
RQAGNAGTRDAARV
HHCCCCCCCHHCCC
>Mature Secondary Structure
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRSDARYWMAAGWCKSTLWVVRWLNGIRYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEE
IEGYENLPDGPAVLLSKHQSAWETLAFPALMPRPLCYVFKRELLYVPFFGWALGMLHMVN
ECCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
INRKEGKNAFTSVIRQGKKRLSEGAWMIMFPEGTRTPVGKQGKYKTGGARFAIETGAPVV
CCHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEE
PIAHNAGRVWPRNSFTKFPGVVTVSIGKPIPSEGLTPDALNSQVEAWIEAEMRRIDPDSY
EEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
RQAGNAGTRDAARV
HHCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]