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The map label for this gene is gmhB [H]

Identifier: 78067499

GI number: 78067499

Start: 3167692

End: 3168255

Strand: Direct

Name: gmhB [H]

Synonym: Bcep18194_A6030

Alternate gene names: 78067499

Gene position: 3167692-3168255 (Clockwise)

Preceding gene: 78067498

Following gene: 78067500

Centisome position: 85.75

GC content: 66.49

Gene sequence:

>564_bases
ATGCCGACCAGCCCCAACCGAAAGCTCGTCGTCCTCGACCGGGACGGCGTGATCAACGTCGATTCGGATGCGTTCATCAA
GACGCCCGACGAATGGATCGCGCTGCCCGGCGCCCTCGAGGCGATCGCCCGGCTCAACCACGCGGGGTATCGCGTGGTCG
TCGCGACCAACCAGTCCGGCATCGGTCGCGGGCTGTTCGACATGGCCACGCTCAACGAGATGCATCTGAAGATGCATCGC
GCGGCGGCCGCGGTCGGCGCACGTATCGACGCGGTGTTCTTCTGCCCGCACACGGCAGAGGATCACTGCGACTGCCGCAA
GCCGAAACCCGGCATGATGCAGATGATCACCGAGCGCTTCGAGATCGATCCCGGTCACACGCCGGTCGTCGGCGATTCGC
TGCGCGACCTGCAGGCCGGCGTCGCGGTCGGCTTCCAGCCGCACCTCGTGCTCACCGGCAAGGGCAAGAAGACGCTCGCC
GCCGGCAACCTGCCGCCCGGCACGAAGGTTCACGACGACCTGCGCGCGTTCGCGCTCGATTTCCTTTCACACGAACACGA
GTGA

Upstream 100 bases:

>100_bases
CCGGCACTGCGCGCGAACCGTCTCGCGCTGCTGTCCGCGCTGCACCAGCAGATGAACTGCGTCGCCGACATCTCGAAGCT
CGCCGCATAAGGGCCGCACG

Downstream 100 bases:

>100_bases
TGCAGCCGCCGCGCGCATCCTCCCTAACGCCTGACTTACGCCGATGCGCTTCGTCCGTTCCCTGCTGCTGCTGATCTACT
TCATCCTGTACACGGTGCCG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MPTSPNRKLVVLDRDGVINVDSDAFIKTPDEWIALPGALEAIARLNHAGYRVVVATNQSGIGRGLFDMATLNEMHLKMHR
AAAAVGARIDAVFFCPHTAEDHCDCRKPKPGMMQMITERFEIDPGHTPVVGDSLRDLQAGVAVGFQPHLVLTGKGKKTLA
AGNLPPGTKVHDDLRAFALDFLSHEHE

Sequences:

>Translated_187_residues
MPTSPNRKLVVLDRDGVINVDSDAFIKTPDEWIALPGALEAIARLNHAGYRVVVATNQSGIGRGLFDMATLNEMHLKMHR
AAAAVGARIDAVFFCPHTAEDHCDCRKPKPGMMQMITERFEIDPGHTPVVGDSLRDLQAGVAVGFQPHLVLTGKGKKTLA
AGNLPPGTKVHDDLRAFALDFLSHEHE
>Mature_186_residues
PTSPNRKLVVLDRDGVINVDSDAFIKTPDEWIALPGALEAIARLNHAGYRVVVATNQSGIGRGLFDMATLNEMHLKMHRA
AAAVGARIDAVFFCPHTAEDHCDCRKPKPGMMQMITERFEIDPGHTPVVGDSLRDLQAGVAVGFQPHLVLTGKGKKTLAA
GNLPPGTKVHDDLRAFALDFLSHEHE

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=153, Percent_Identity=37.9084967320261, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082027, Length=141, Percent_Identity=31.9148936170213, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 20306; Mature: 20174

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSPNRKLVVLDRDGVINVDSDAFIKTPDEWIALPGALEAIARLNHAGYRVVVATNQSG
CCCCCCCEEEEEECCCEEEECCCCEEECCHHHEECCHHHHHHHHHCCCCEEEEEEECCCC
IGRGLFDMATLNEMHLKMHRAAAAVGARIDAVFFCPHTAEDHCDCRKPKPGMMQMITERF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
EIDPGHTPVVGDSLRDLQAGVAVGFQPHLVLTGKGKKTLAAGNLPPGTKVHDDLRAFALD
CCCCCCCCCCCCHHHHHHHCEECCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHH
FLSHEHE
HHHCCCC
>Mature Secondary Structure 
PTSPNRKLVVLDRDGVINVDSDAFIKTPDEWIALPGALEAIARLNHAGYRVVVATNQSG
CCCCCCEEEEEECCCEEEECCCCEEECCHHHEECCHHHHHHHHHCCCCEEEEEEECCCC
IGRGLFDMATLNEMHLKMHRAAAAVGARIDAVFFCPHTAEDHCDCRKPKPGMMQMITERF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
EIDPGHTPVVGDSLRDLQAGVAVGFQPHLVLTGKGKKTLAAGNLPPGTKVHDDLRAFALD
CCCCCCCCCCCCHHHHHHHCEECCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHH
FLSHEHE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 12101286 [H]