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The map label for this gene is hemH

Identifier: 78067425

GI number: 78067425

Start: 3085280

End: 3086170

Strand: Reverse

Name: hemH

Synonym: Bcep18194_A5956

Alternate gene names: 78067425

Gene position: 3086170-3085280 (Counterclockwise)

Preceding gene: 78067426

Following gene: 78067424

Centisome position: 83.54

GC content: 67.0

Gene sequence:

>891_bases
ATGTCTACCCTCTACGAATCCACGCTCCGCTCGCTGCCGCTCCTCGGTCGCGGCAAGGTCCGCGATAACTACGCGGTCGG
CAACGACAAGCTCCTGATCGTCACGACCGATCGCCTGTCGGCATTCGACGTGGTGATGGGCGAGCCGATTCCGAACAAGG
GGCGCGTGCTGAACCAGATGGCGAACTTCTGGTTCGACAAGCTCGCGCACATCGTGCCGAACCACCTGACGGGCGACGCG
CCGGAAGCCGTCGTCGCGGCCGACGAGGTCGAGCAGGTGAAGGGCCGCGGCGTGGTCGTCAAGCGCCTCGAGCCGATCAT
GATCGAAGCGGTCGTGCGCGGCTACCTGGCCGGCAGCGGCTGGAAGGAATACCAGGCGTCGGGCGCCGTGTGCGGCGTGC
AGCTGCCGGAAGGCCTGCAGAACGCGCAGAAGCTGCCCGAGCCGATCTTCACGCCGGCCGCGAAGGCCGAGATGGGCGAG
CACGACGAGAACATCACGTTCGAGGAAACCGAGCGCCGCATCGGCACCGAGCTGGCCGCGACGATCCGCGACATCTCGAT
CAAGCTGTACAAGGAAGCGGCTGACTACGCGGCGACGCGCGGCATCATCATCGCCGACACGAAGTTCGAATTCGGCCTCG
ACAACCACGGCCAGCTGTACCTGATGGACGAAGTGCTGACGGCCGATTCGTCGCGCTTCTGGCCGGCCGACCAGTACGAA
GTCGGCACGAACCCGCCGTCGTTCGACAAGCAGTTCGTGCGCGACTGGCTCGAGGCGCAGCCGTGGGGCAAGACGGCGCC
GGCGCCGGCGCTGCCGGCCGACGTCGTCGAGAAGACGGCCGCGAAGTACCAGGAAGCGCTCGAGCGCATCACGGGCCAGG
CGCTCGCCTGA

Upstream 100 bases:

>100_bases
CGCCCGGCCGGTTCGCCGACGTATTGCAAGACCGCCGTTCCCGCCTGCCGCGGGGAACGGCGTTTCCCTTTTTGTTTGGC
TCCTTATCTGCGAAAAGACG

Downstream 100 bases:

>100_bases
TCGGACTTTGCATGGGACCAGAGTAAGTGCTGAAGCACTAACTCTGGTCGACAGGAACTGAACAAATGAGTGAAATCCAG
ACTGCCCACACGCACAGCGC

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSTLYESTLRSLPLLGRGKVRDNYAVGNDKLLIVTTDRLSAFDVVMGEPIPNKGRVLNQMANFWFDKLAHIVPNHLTGDA
PEAVVAADEVEQVKGRGVVVKRLEPIMIEAVVRGYLAGSGWKEYQASGAVCGVQLPEGLQNAQKLPEPIFTPAAKAEMGE
HDENITFEETERRIGTELAATIRDISIKLYKEAADYAATRGIIIADTKFEFGLDNHGQLYLMDEVLTADSSRFWPADQYE
VGTNPPSFDKQFVRDWLEAQPWGKTAPAPALPADVVEKTAAKYQEALERITGQALA

Sequences:

>Translated_296_residues
MSTLYESTLRSLPLLGRGKVRDNYAVGNDKLLIVTTDRLSAFDVVMGEPIPNKGRVLNQMANFWFDKLAHIVPNHLTGDA
PEAVVAADEVEQVKGRGVVVKRLEPIMIEAVVRGYLAGSGWKEYQASGAVCGVQLPEGLQNAQKLPEPIFTPAAKAEMGE
HDENITFEETERRIGTELAATIRDISIKLYKEAADYAATRGIIIADTKFEFGLDNHGQLYLMDEVLTADSSRFWPADQYE
VGTNPPSFDKQFVRDWLEAQPWGKTAPAPALPADVVEKTAAKYQEALERITGQALA
>Mature_295_residues
STLYESTLRSLPLLGRGKVRDNYAVGNDKLLIVTTDRLSAFDVVMGEPIPNKGRVLNQMANFWFDKLAHIVPNHLTGDAP
EAVVAADEVEQVKGRGVVVKRLEPIMIEAVVRGYLAGSGWKEYQASGAVCGVQLPEGLQNAQKLPEPIFTPAAKAEMGEH
DENITFEETERRIGTELAATIRDISIKLYKEAADYAATRGIIIADTKFEFGLDNHGQLYLMDEVLTADSSRFWPADQYEV
GTNPPSFDKQFVRDWLEAQPWGKTAPAPALPADVVEKTAAKYQEALERITGQALA

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=291, Percent_Identity=46.0481099656357, Blast_Score=265, Evalue=4e-72,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 32603; Mature: 32472

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLYESTLRSLPLLGRGKVRDNYAVGNDKLLIVTTDRLSAFDVVMGEPIPNKGRVLNQM
CCHHHHHHHHHCCCCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHCCCCCCCHHHHHHH
ANFWFDKLAHIVPNHLTGDAPEAVVAADEVEQVKGRGVVVKRLEPIMIEAVVRGYLAGSG
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCC
WKEYQASGAVCGVQLPEGLQNAQKLPEPIFTPAAKAEMGEHDENITFEETERRIGTELAA
HHHHHCCCCEEECCCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHH
TIRDISIKLYKEAADYAATRGIIIADTKFEFGLDNHGQLYLMDEVLTADSSRFWPADQYE
HHHHHHHHHHHHHHHHHHHCCEEEEECCEECCCCCCCCEEEEHHHHHCCCCCCCCCCCCC
VGTNPPSFDKQFVRDWLEAQPWGKTAPAPALPADVVEKTAAKYQEALERITGQALA
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STLYESTLRSLPLLGRGKVRDNYAVGNDKLLIVTTDRLSAFDVVMGEPIPNKGRVLNQM
CHHHHHHHHHCCCCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHCCCCCCCHHHHHHH
ANFWFDKLAHIVPNHLTGDAPEAVVAADEVEQVKGRGVVVKRLEPIMIEAVVRGYLAGSG
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCC
WKEYQASGAVCGVQLPEGLQNAQKLPEPIFTPAAKAEMGEHDENITFEETERRIGTELAA
HHHHHCCCCEEECCCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHH
TIRDISIKLYKEAADYAATRGIIIADTKFEFGLDNHGQLYLMDEVLTADSSRFWPADQYE
HHHHHHHHHHHHHHHHHHHCCEEEEECCEECCCCCCCCEEEEHHHHHCCCCCCCCCCCCC
VGTNPPSFDKQFVRDWLEAQPWGKTAPAPALPADVVEKTAAKYQEALERITGQALA
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA