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The map label for this gene is btr [H]

Identifier: 78067341

GI number: 78067341

Start: 2992936

End: 2993643

Strand: Direct

Name: btr [H]

Synonym: Bcep18194_A5872

Alternate gene names: 78067341

Gene position: 2992936-2993643 (Clockwise)

Preceding gene: 78067337

Following gene: 78067342

Centisome position: 81.02

GC content: 70.76

Gene sequence:

>708_bases
ATGCCCTCTTCGCTCGCCCCGTACCTGCCGCAGATCGAAGCGAACCCGTGGTTCGCCGCGCTGCCGCCCGCGTTGCGCGC
GGACCTGCTCGCCCGCGCGGCGTTGCGCCGGCTGCCGGCCGGCCACGCGCTGTTCCGGCGCGGCGACCCGCCGTGCGGGC
TGTACGCGGTACTGGCCGGTTCACTCACGATAGGTGCGGTCGACCCGCAGGGCAAGGAAGCGCTGCTGACGGTCGCCGAG
CCCGTCACCTGGTTCGGTGAAATCGCACTATTCGACGGTCAGCCGCGCACGCACGACGCGATCGCACTCGACGACGCGCT
GCTGCTGCACGTCCCGCAGGCCGCGCTGCTCGCGATCCTCGACGCGACGCCGCAATACTGGCGGCAGTTCGCGCTGCTGA
TGGCGCAGAAGCTGCGCCTGAGCTTCCTGACCGTCGAATCGATGAGCGTGATGCCGGCTGCGCAGCGGCTTGCCGCCCGG
CTGCTGATGATCGCCGACGGCTACGGCGGGATCAGCGCCGGCCGCACCCATATCCGGCTGTCGCAGGAAAAGCTCGCGGC
GATGCTGTCGCTGACGCGGCAGACCACCAACCAGTTGCTGAAGGCGCTGCAGGCCGACGGCGTCGTGCGGCTGCACGTCG
GCGAGATCGAGCTCGTCGACGTCGATGCGCTACGGCGCGCGAGCGGGTTGCCCGACAGCCTGCGCTGA

Upstream 100 bases:

>100_bases
GGTCTTCGAGCGTCTTCATCGCGTCTCCTGGTCGGTGGTTGAGCGCTATGATGCGCGTCACGCCCGAGAACCTCTGTCAG
CTACCCGACATCGCGTGCCC

Downstream 100 bases:

>100_bases
GCCCCGGCACCGCCGTCGCGCGGCCTCCCCGCCGTCACCGCGTTGCGCTATCGTGGCGGCTCGTCCGTTCATCCGCCCGC
ACCGCCTTGAGCACGTCGAC

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MPSSLAPYLPQIEANPWFAALPPALRADLLARAALRRLPAGHALFRRGDPPCGLYAVLAGSLTIGAVDPQGKEALLTVAE
PVTWFGEIALFDGQPRTHDAIALDDALLLHVPQAALLAILDATPQYWRQFALLMAQKLRLSFLTVESMSVMPAAQRLAAR
LLMIADGYGGISAGRTHIRLSQEKLAAMLSLTRQTTNQLLKALQADGVVRLHVGEIELVDVDALRRASGLPDSLR

Sequences:

>Translated_235_residues
MPSSLAPYLPQIEANPWFAALPPALRADLLARAALRRLPAGHALFRRGDPPCGLYAVLAGSLTIGAVDPQGKEALLTVAE
PVTWFGEIALFDGQPRTHDAIALDDALLLHVPQAALLAILDATPQYWRQFALLMAQKLRLSFLTVESMSVMPAAQRLAAR
LLMIADGYGGISAGRTHIRLSQEKLAAMLSLTRQTTNQLLKALQADGVVRLHVGEIELVDVDALRRASGLPDSLR
>Mature_234_residues
PSSLAPYLPQIEANPWFAALPPALRADLLARAALRRLPAGHALFRRGDPPCGLYAVLAGSLTIGAVDPQGKEALLTVAEP
VTWFGEIALFDGQPRTHDAIALDDALLLHVPQAALLAILDATPQYWRQFALLMAQKLRLSFLTVESMSVMPAAQRLAARL
LMIADGYGGISAGRTHIRLSQEKLAAMLSLTRQTTNQLLKALQADGVVRLHVGEIELVDVDALRRASGLPDSLR

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=186, Percent_Identity=20.4301075268817, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25348; Mature: 25217

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSLAPYLPQIEANPWFAALPPALRADLLARAALRRLPAGHALFRRGDPPCGLYAVLAG
CCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHC
SLTIGAVDPQGKEALLTVAEPVTWFGEIALFDGQPRTHDAIALDDALLLHVPQAALLAIL
CEEEECCCCCCCHHEEEHHCCHHHHEEEEEECCCCCCCCCEECCCHHEECCCHHHHHHHH
DATPQYWRQFALLMAQKLRLSFLTVESMSVMPAAQRLAARLLMIADGYGGISAGRTHIRL
HCCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEE
SQEKLAAMLSLTRQTTNQLLKALQADGVVRLHVGEIELVDVDALRRASGLPDSLR
CHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PSSLAPYLPQIEANPWFAALPPALRADLLARAALRRLPAGHALFRRGDPPCGLYAVLAG
CCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHC
SLTIGAVDPQGKEALLTVAEPVTWFGEIALFDGQPRTHDAIALDDALLLHVPQAALLAIL
CEEEECCCCCCCHHEEEHHCCHHHHEEEEEECCCCCCCCCEECCCHHEECCCHHHHHHHH
DATPQYWRQFALLMAQKLRLSFLTVESMSVMPAAQRLAARLLMIADGYGGISAGRTHIRL
HCCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEE
SQEKLAAMLSLTRQTTNQLLKALQADGVVRLHVGEIELVDVDALRRASGLPDSLR
CHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]