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The map label for this gene is panE [C]

Identifier: 78067339

GI number: 78067339

Start: 2991291

End: 2992337

Strand: Reverse

Name: panE [C]

Synonym: Bcep18194_A5870

Alternate gene names: 78067339

Gene position: 2992337-2991291 (Counterclockwise)

Preceding gene: 78067340

Following gene: 78067338

Centisome position: 81.0

GC content: 73.45

Gene sequence:

>1047_bases
ATGTCTGACGCACCGGTCTGCGTGTTCGGCGCGGGCGCCGTCGGCTGCTATCTCGGCGGACGGCTCGCGGCGGCGGGCGC
GAATGTGACGCTCGTCGGCCGCGCACGGATCGGCGACGCGATTCATCGGCACGGGCTGACGCTGACCGACCAGCGCGGCT
ATCGCGCGACGCTCGCGCCGGCCGATGTCGTGTTCGAGACCGATCCGGCGGCTGCGGCAGCCGCGCGGCTTGTGCTCGTG
GCGGTGAAATCGGCGGCGACACGTGAGGCCGCGGCGCAGCTTGCCGGCGTGCTGCGGCCCGGCACGGTCGTGATCAGCTT
CCAGAACGGCCTGCACAACGCCGACGTGCTGCGCGAAGTGCTGCCGCAAGCGACCGTGCTGGCCGGCATGGTGCCGTTCA
ACGTGATCGAGCGTGAGCCCGGTGCGTTTCACCAGGGCTCGGCCGGTGCGCTGGCGGCCGAAGCGTCCCCCACGCTGCAG
CCGTTCGCCGGTGCATTCGCGCGCGCCGGGCTGCCGCTCGCGCTGCATCGCGACATGCCGGCCGTGCAGTGGGCGAAGCT
GCTGCTCAACCTGAACAACGCGGTCAACGCGCTCGCGAACCTGCCGCTGCGCGACGAACTCGCACAACGCGCGTACCGGC
GCTGTGTTGCGCTTGCGCAGCGCGAAGCGCTGCATTGGCTGGCGCGGGCCGCGATCCGGCCTGCGCGGCTGACGCCGTTG
CCGGCCGGGTGGATCCCGGCCGTGCTCGACCTGCCCGATCCCGCGTTCCGCGTGCTCGGCGGCCGGATGCTCGCGATCGA
TCCGCTCGCGCGTTCGTCGATGTCCGACGATCTCGCGGCGGGGCGGGCGACGGAAGTCGAGTGGATCAACGGCGAGGTCG
TGCGGCTGGCCGCACGCTTTGGCGGGCAGGCGCCCGTCAATGCGCGACTGTGTGCGCTCGTGCACGACGCGGAACGCGCG
GCGGCGCGCCCGGCCTGGCGCGGCGAGGCGCTGTGGGCCGAGCTGACCGCTCAGGTGCCGCGCGCGGGCGACGTGCGGGC
CGCGTAG

Upstream 100 bases:

>100_bases
TTCGTCGTGGCCGAGGTCGCGTTCTTCGCGGGGCTGCGCGCCGACGTGCGCCGCGAAGTCGAGCGGCGGGCCGGCCCCGT
GCACGGCGGCGCGCATTCGC

Downstream 100 bases:

>100_bases
GGGCTGGCAGCCCGTCGCGCGAGGTGCCGCACGCGGTGCGCAACGGCTAAGATGCGGGGTGCGTCATACGACGCCTATGC
GGAGCCGTCATCATGGTGGA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSDAPVCVFGAGAVGCYLGGRLAAAGANVTLVGRARIGDAIHRHGLTLTDQRGYRATLAPADVVFETDPAAAAAARLVLV
AVKSAATREAAAQLAGVLRPGTVVISFQNGLHNADVLREVLPQATVLAGMVPFNVIEREPGAFHQGSAGALAAEASPTLQ
PFAGAFARAGLPLALHRDMPAVQWAKLLLNLNNAVNALANLPLRDELAQRAYRRCVALAQREALHWLARAAIRPARLTPL
PAGWIPAVLDLPDPAFRVLGGRMLAIDPLARSSMSDDLAAGRATEVEWINGEVVRLAARFGGQAPVNARLCALVHDAERA
AARPAWRGEALWAELTAQVPRAGDVRAA

Sequences:

>Translated_348_residues
MSDAPVCVFGAGAVGCYLGGRLAAAGANVTLVGRARIGDAIHRHGLTLTDQRGYRATLAPADVVFETDPAAAAAARLVLV
AVKSAATREAAAQLAGVLRPGTVVISFQNGLHNADVLREVLPQATVLAGMVPFNVIEREPGAFHQGSAGALAAEASPTLQ
PFAGAFARAGLPLALHRDMPAVQWAKLLLNLNNAVNALANLPLRDELAQRAYRRCVALAQREALHWLARAAIRPARLTPL
PAGWIPAVLDLPDPAFRVLGGRMLAIDPLARSSMSDDLAAGRATEVEWINGEVVRLAARFGGQAPVNARLCALVHDAERA
AARPAWRGEALWAELTAQVPRAGDVRAA
>Mature_347_residues
SDAPVCVFGAGAVGCYLGGRLAAAGANVTLVGRARIGDAIHRHGLTLTDQRGYRATLAPADVVFETDPAAAAAARLVLVA
VKSAATREAAAQLAGVLRPGTVVISFQNGLHNADVLREVLPQATVLAGMVPFNVIEREPGAFHQGSAGALAAEASPTLQP
FAGAFARAGLPLALHRDMPAVQWAKLLLNLNNAVNALANLPLRDELAQRAYRRCVALAQREALHWLARAAIRPARLTPLP
AGWIPAVLDLPDPAFRVLGGRMLAIDPLARSSMSDDLAAGRATEVEWINGEVVRLAARFGGQAPVNARLCALVHDAERAA
ARPAWRGEALWAELTAQVPRAGDVRAA

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 36449; Mature: 36318

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAPVCVFGAGAVGCYLGGRLAAAGANVTLVGRARIGDAIHRHGLTLTDQRGYRATLAP
CCCCCEEEEECCHHHHHHCCEEEECCCCEEEEECHHHHHHHHHCCCEEECCCCCEEEECC
ADVVFETDPAAAAAARLVLVAVKSAATREAAAQLAGVLRPGTVVISFQNGLHNADVLREV
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
LPQATVLAGMVPFNVIEREPGAFHQGSAGALAAEASPTLQPFAGAFARAGLPLALHRDMP
HHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHCCCCEEECCCCC
AVQWAKLLLNLNNAVNALANLPLRDELAQRAYRRCVALAQREALHWLARAAIRPARLTPL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PAGWIPAVLDLPDPAFRVLGGRMLAIDPLARSSMSDDLAAGRATEVEWINGEVVRLAARF
CCCCCCCEECCCCHHHHHHCCEEEEECHHHHCCCCHHHHCCCCCEEEECCCHHHHHHHHC
GGQAPVNARLCALVHDAERAAARPAWRGEALWAELTAQVPRAGDVRAA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SDAPVCVFGAGAVGCYLGGRLAAAGANVTLVGRARIGDAIHRHGLTLTDQRGYRATLAP
CCCCEEEEECCHHHHHHCCEEEECCCCEEEEECHHHHHHHHHCCCEEECCCCCEEEECC
ADVVFETDPAAAAAARLVLVAVKSAATREAAAQLAGVLRPGTVVISFQNGLHNADVLREV
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
LPQATVLAGMVPFNVIEREPGAFHQGSAGALAAEASPTLQPFAGAFARAGLPLALHRDMP
HHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHCCCCEEECCCCC
AVQWAKLLLNLNNAVNALANLPLRDELAQRAYRRCVALAQREALHWLARAAIRPARLTPL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PAGWIPAVLDLPDPAFRVLGGRMLAIDPLARSSMSDDLAAGRATEVEWINGEVVRLAARF
CCCCCCCEECCCCHHHHHHCCEEEEECHHHHCCCCHHHHCCCCCEEEECCCHHHHHHHHC
GGQAPVNARLCALVHDAERAAARPAWRGEALWAELTAQVPRAGDVRAA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]