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The map label for this gene is hoxN [H]

Identifier: 78067330

GI number: 78067330

Start: 2980458

End: 2981501

Strand: Direct

Name: hoxN [H]

Synonym: Bcep18194_A5861

Alternate gene names: 78067330

Gene position: 2980458-2981501 (Clockwise)

Preceding gene: 78067329

Following gene: 78067331

Centisome position: 80.68

GC content: 67.53

Gene sequence:

>1044_bases
ATGGATCGCGATTCGTCAGATGGAATGATCCCGATGCCGCCCACCCCTGCCCTGCGCCGCCTGCTGATCCTCTATGGCGG
CCTGATCGCCGCGAACGCCGCCGTCTTGCTGTGGGCGCTCGCCGTGTTGCGCGATCATCCGTTGCTGCTCGGCACCGCGG
CGATCGCGTATGGGCTCGGGCTGCGTCACGCAGTCGACGCCGATCACATCGCCGCGATCGACGTTGCGACGCGCAAGCTG
ATGCAGGAAGGGCAGCGTCCGGTGAGCGTCGGGCTGTTCTTCTCGCTCGGCCATTCGACGATCGTGATCGCCGCGACGCT
CGGCGTCGCGCTGACCGCGTTCGCGCTACGCGACCGGTTCGATGCATTCCGCGAGATCGGCGGCACGATCGGCACGGCGG
TGTCGGCCACCTTCCTGCTCGTGCTCGCGTGCGTGAACCTGGTGATCCTGCGCGACGTGTGGCGGCGCTATCGCGGCACG
CACGGGCACGCACACGATGCCGCGCATGTGCACCGTCCTGCCGGGCTCGTGTCCCGGCTGCTGCGTCCGTTGTTCCGGTT
CGTGTCGAAGAGCTGGCACATGTATCCGGTCGGCGTGCTGTTCGGGCTAGGTTTCGATACTGCAACCGAAATCGGCCTGC
TCGCGATTGCCGCCGCGCAGGCGAGCCAGGGGTTGCCGGTCTATACGGTCATGCTGTTTCCCGCGCTTTTCACCGCCGGC
ATGACGCTGATCGACTCGACCGACAACGTGCTGATGATTCACGCGTACGGCTGGGCGATGGACGATCCGCAGCGCAAGCT
GCTCTACAACGCGAGCATCACGTTCGTGTCGGCGGCCGTCGCGCTGGCGATCGGCGGGATCGAGGCAGCCGGCCTGCTGG
CCGACAAGCTGTCGCTGACGGGCCCCGTGCGCGACGCGCTCGATGCGCTCGGCGAACGCTTCGGCTCGATCGGCTACGGC
ATCGTCGCCCTGTTCCTCGTCTGCTGGATCGCGTCGATCCTGTTCCACCGCTGGCAGCGCGCGGCCGATGCGCCTGCGCG
CTGA

Upstream 100 bases:

>100_bases
GGCAAGGCCCGTCCGGTTCCGGACGGGCTTTTTTCATTCGGCGCGCGCGGCGTTCGCGGCTTTTTGATCGGCACGCCAGG
CATTTTTTTCGCGTGCCACA

Downstream 100 bases:

>100_bases
ACTTAGCTCAGACGTTTCATTCCGGAAACAAAACTCCCCCGAAGACGTTGCATGCGCCGTCGCACGCTTGCGTGCGCCTT
GCGCGACGGGCGCAAGCGGC

Product: high-affinity nickel-transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MDRDSSDGMIPMPPTPALRRLLILYGGLIAANAAVLLWALAVLRDHPLLLGTAAIAYGLGLRHAVDADHIAAIDVATRKL
MQEGQRPVSVGLFFSLGHSTIVIAATLGVALTAFALRDRFDAFREIGGTIGTAVSATFLLVLACVNLVILRDVWRRYRGT
HGHAHDAAHVHRPAGLVSRLLRPLFRFVSKSWHMYPVGVLFGLGFDTATEIGLLAIAAAQASQGLPVYTVMLFPALFTAG
MTLIDSTDNVLMIHAYGWAMDDPQRKLLYNASITFVSAAVALAIGGIEAAGLLADKLSLTGPVRDALDALGERFGSIGYG
IVALFLVCWIASILFHRWQRAADAPAR

Sequences:

>Translated_347_residues
MDRDSSDGMIPMPPTPALRRLLILYGGLIAANAAVLLWALAVLRDHPLLLGTAAIAYGLGLRHAVDADHIAAIDVATRKL
MQEGQRPVSVGLFFSLGHSTIVIAATLGVALTAFALRDRFDAFREIGGTIGTAVSATFLLVLACVNLVILRDVWRRYRGT
HGHAHDAAHVHRPAGLVSRLLRPLFRFVSKSWHMYPVGVLFGLGFDTATEIGLLAIAAAQASQGLPVYTVMLFPALFTAG
MTLIDSTDNVLMIHAYGWAMDDPQRKLLYNASITFVSAAVALAIGGIEAAGLLADKLSLTGPVRDALDALGERFGSIGYG
IVALFLVCWIASILFHRWQRAADAPAR
>Mature_347_residues
MDRDSSDGMIPMPPTPALRRLLILYGGLIAANAAVLLWALAVLRDHPLLLGTAAIAYGLGLRHAVDADHIAAIDVATRKL
MQEGQRPVSVGLFFSLGHSTIVIAATLGVALTAFALRDRFDAFREIGGTIGTAVSATFLLVLACVNLVILRDVWRRYRGT
HGHAHDAAHVHRPAGLVSRLLRPLFRFVSKSWHMYPVGVLFGLGFDTATEIGLLAIAAAQASQGLPVYTVMLFPALFTAG
MTLIDSTDNVLMIHAYGWAMDDPQRKLLYNASITFVSAAVALAIGGIEAAGLLADKLSLTGPVRDALDALGERFGSIGYG
IVALFLVCWIASILFHRWQRAADAPAR

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 37167; Mature: 37167

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRDSSDGMIPMPPTPALRRLLILYGGLIAANAAVLLWALAVLRDHPLLLGTAAIAYGLG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
LRHAVDADHIAAIDVATRKLMQEGQRPVSVGLFFSLGHSTIVIAATLGVALTAFALRDRF
HHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEHEEECCCCHHHHHHHHHHHHHHHHHHHHH
DAFREIGGTIGTAVSATFLLVLACVNLVILRDVWRRYRGTHGHAHDAAHVHRPAGLVSRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCHHHHHHHH
LRPLFRFVSKSWHMYPVGVLFGLGFDTATEIGLLAIAAAQASQGLPVYTVMLFPALFTAG
HHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
MTLIDSTDNVLMIHAYGWAMDDPQRKLLYNASITFVSAAVALAIGGIEAAGLLADKLSLT
CCEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
GPVRDALDALGERFGSIGYGIVALFLVCWIASILFHRWQRAADAPAR
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDRDSSDGMIPMPPTPALRRLLILYGGLIAANAAVLLWALAVLRDHPLLLGTAAIAYGLG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
LRHAVDADHIAAIDVATRKLMQEGQRPVSVGLFFSLGHSTIVIAATLGVALTAFALRDRF
HHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEHEEECCCCHHHHHHHHHHHHHHHHHHHHH
DAFREIGGTIGTAVSATFLLVLACVNLVILRDVWRRYRGTHGHAHDAAHVHRPAGLVSRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCHHHHHHHH
LRPLFRFVSKSWHMYPVGVLFGLGFDTATEIGLLAIAAAQASQGLPVYTVMLFPALFTAG
HHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
MTLIDSTDNVLMIHAYGWAMDDPQRKLLYNASITFVSAAVALAIGGIEAAGLLADKLSLT
CCEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
GPVRDALDALGERFGSIGYGIVALFLVCWIASILFHRWQRAADAPAR
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]