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The map label for this gene is otsA [H]

Identifier: 78067188

GI number: 78067188

Start: 2824795

End: 2826216

Strand: Reverse

Name: otsA [H]

Synonym: Bcep18194_A5719

Alternate gene names: 78067188

Gene position: 2826216-2824795 (Counterclockwise)

Preceding gene: 78067189

Following gene: 78067187

Centisome position: 76.51

GC content: 67.37

Gene sequence:

>1422_bases
ATGAGCAGATTGATCGTGGTATCGAACCGTGTCGCCGCCGGCGAGGACACGCGCCCGAGCGCGGGTGGCCTGGCGGTCGG
CGTGATGGACGCGCTGAAGGAAACGGGCGGCGTCTGGTTCGGCTGGAACGGCGAGATCGTCGACGCACCCGATACCGAAC
CCGCGATCCAGCAGGACGGCAACGTCACCTATGCGACGGTCGGGCTGAACCGGCGCGACTACGATCAGTACTACCGCGGC
TTCTCGAACGCGACGCTGTGGCCGGTGTTCCATTACCGCGGCGATCTCGCGCGCTTCGACCGTCAGGAGTACGCGGGCTA
TCTGCGCGTGAACGCGATGCTCGCCAAGCAGCTTGCCGCCCTGCTGCGCCCCGACGACCTGATCTGGGTACACGACTATC
ACCTGTTGCCGTTCGCGCATTACCTGCGCGAGCTCGGCGTGAAGAACCCGATCGGCTTCTTCCTGCACATTCCGTTTCCG
TCGCCCGACATGCTGCGTCTCGTGCCGCCGCACGAGGAACTCGTGAAGTTCATGTGCGCGTACGACGTCGCGGGCTTCCA
GACCGAGACCGACAAGCAGGCGTTCACCGACTACATCGAACGGCGCGGGATCGGTGCGGCGAGCGACGACGGAATGCTGC
ACGCGCATGGCCGCGTCGTGAAGGTCGCCGCCTATCCGATCGGTGTGCATCCCGACGCGATCGCGCAGGCGGCCGTCCAG
TACAGCGCGCGCAAGCCGGTGAAGATGCTGCGCGAGGCGCTCGACGGCCGCAAGCTGGTGATGAGCGTCGACCGCCTCGA
CTACTCGAAGGGGCTCGTCGAGCGCTTCCAGTCGTTCGAGCGGATGCTCGCGAACGCGCCGGGCTGGCAGGGGCGCGTGT
CGCTCCTGCAGATCGCGCCGCCGACGCGTTCCGACGTGAAGACCTATCAGGACATTCGCGAAACGCTCGAAGGCGAGGCC
GGCCGCATCAACGGCCGCTTCTCGCAGCTGGACTGGACCCCGATCCAGTACCTGAACCGCAAGTACGAGCGCAACCTGCT
GATGGCGTTCTTCCGGATGTCGCAGGTCGGCTACGTGACGCCGCTGCGCGACGGGATGAATCTCGTCGCGAAGGAGTACG
TCGCGTCGCAGGATCCGGCCGATCCGGGCGTGCTCGTGCTGTCGGAGTTCGCGGGTGCGGCAGCCGAGCTGACCGGCGCG
CTCCTCGTCAATCCGTATGACCTGTCGCAGATGGCCGAGGCGCTCGAGCGCGCGCTGTCGATGCCGCTCGCGGAGCGGCA
GGCGCGCCACGAGGAAAACCTCGCGCGGTTGCGTGTGAACGACCTGTCGGTCTGGCGCGATACGTTCGTCGCCGACTTGC
GCAGTGTCGCGGCTGCCGCGTCGGTCACGCGGCGCGCGGGCCGGCGGGTCGCGCATGCGTGA

Upstream 100 bases:

>100_bases
ATTGCTCACGTCTGAATCGCCGCACGGCCGCCTTCGGGTCGCCGTGTCCGCCTTGGCGCGCGCCGCGCGCCAGCCAATCG
AATCGAGGAGGGGAAGCCGC

Downstream 100 bases:

>100_bases
GGTCGTGGAAGGGCCCGGCGTCGCCGACGACGACGCCTCCCGCCGCTTCTTCGTCGTGACCGGTGGTCCGGGCTCGGGCA
AGAGCACGTTGCTCGACGCG

Product: Alpha,alpha-trehalose-phosphate synthase (UDP-forming)

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSRLIVVSNRVAAGEDTRPSAGGLAVGVMDALKETGGVWFGWNGEIVDAPDTEPAIQQDGNVTYATVGLNRRDYDQYYRG
FSNATLWPVFHYRGDLARFDRQEYAGYLRVNAMLAKQLAALLRPDDLIWVHDYHLLPFAHYLRELGVKNPIGFFLHIPFP
SPDMLRLVPPHEELVKFMCAYDVAGFQTETDKQAFTDYIERRGIGAASDDGMLHAHGRVVKVAAYPIGVHPDAIAQAAVQ
YSARKPVKMLREALDGRKLVMSVDRLDYSKGLVERFQSFERMLANAPGWQGRVSLLQIAPPTRSDVKTYQDIRETLEGEA
GRINGRFSQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELTGA
LLVNPYDLSQMAEALERALSMPLAERQARHEENLARLRVNDLSVWRDTFVADLRSVAAAASVTRRAGRRVAHA

Sequences:

>Translated_473_residues
MSRLIVVSNRVAAGEDTRPSAGGLAVGVMDALKETGGVWFGWNGEIVDAPDTEPAIQQDGNVTYATVGLNRRDYDQYYRG
FSNATLWPVFHYRGDLARFDRQEYAGYLRVNAMLAKQLAALLRPDDLIWVHDYHLLPFAHYLRELGVKNPIGFFLHIPFP
SPDMLRLVPPHEELVKFMCAYDVAGFQTETDKQAFTDYIERRGIGAASDDGMLHAHGRVVKVAAYPIGVHPDAIAQAAVQ
YSARKPVKMLREALDGRKLVMSVDRLDYSKGLVERFQSFERMLANAPGWQGRVSLLQIAPPTRSDVKTYQDIRETLEGEA
GRINGRFSQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELTGA
LLVNPYDLSQMAEALERALSMPLAERQARHEENLARLRVNDLSVWRDTFVADLRSVAAAASVTRRAGRRVAHA
>Mature_472_residues
SRLIVVSNRVAAGEDTRPSAGGLAVGVMDALKETGGVWFGWNGEIVDAPDTEPAIQQDGNVTYATVGLNRRDYDQYYRGF
SNATLWPVFHYRGDLARFDRQEYAGYLRVNAMLAKQLAALLRPDDLIWVHDYHLLPFAHYLRELGVKNPIGFFLHIPFPS
PDMLRLVPPHEELVKFMCAYDVAGFQTETDKQAFTDYIERRGIGAASDDGMLHAHGRVVKVAAYPIGVHPDAIAQAAVQY
SARKPVKMLREALDGRKLVMSVDRLDYSKGLVERFQSFERMLANAPGWQGRVSLLQIAPPTRSDVKTYQDIRETLEGEAG
RINGRFSQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELTGAL
LVNPYDLSQMAEALERALSMPLAERQARHEENLARLRVNDLSVWRDTFVADLRSVAAAASVTRRAGRRVAHA

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=467, Percent_Identity=51.8201284796574, Blast_Score=483, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI115533560, Length=420, Percent_Identity=29.7619047619048, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI115533558, Length=420, Percent_Identity=29.7619047619048, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71987012, Length=437, Percent_Identity=29.0617848970252, Blast_Score=158, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6319602, Length=468, Percent_Identity=33.974358974359, Blast_Score=289, Evalue=7e-79,
Organism=Saccharomyces cerevisiae, GI6320279, Length=402, Percent_Identity=27.1144278606965, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6323537, Length=383, Percent_Identity=27.154046997389, Blast_Score=173, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6323917, Length=373, Percent_Identity=27.0777479892761, Blast_Score=165, Evalue=1e-41,
Organism=Drosophila melanogaster, GI19920676, Length=498, Percent_Identity=36.9477911646586, Blast_Score=287, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 52930; Mature: 52799

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLIVVSNRVAAGEDTRPSAGGLAVGVMDALKETGGVWFGWNGEIVDAPDTEPAIQQDG
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCEEECCCCCCCCHHCCC
NVTYATVGLNRRDYDQYYRGFSNATLWPVFHYRGDLARFDRQEYAGYLRVNAMLAKQLAA
CEEEEEECCCCCCHHHHHCCCCCCEEEEEHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHH
LLRPDDLIWVHDYHLLPFAHYLRELGVKNPIGFFLHIPFPSPDMLRLVPPHEELVKFMCA
HHCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEECCCHHHHHHHHHH
YDVAGFQTETDKQAFTDYIERRGIGAASDDGMLHAHGRVVKVAAYPIGVHPDAIAQAAVQ
HHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEEECCCCHHHHHHHHHH
YSARKPVKMLREALDGRKLVMSVDRLDYSKGLVERFQSFERMLANAPGWQGRVSLLQIAP
HHCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
PTRSDVKTYQDIRETLEGEAGRINGRFSQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVT
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELTGALLVNPYDLSQMAEALERALS
CCHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCHHHHHCCEEEECCCCHHHHHHHHHHHHC
MPLAERQARHEENLARLRVNDLSVWRDTFVADLRSVAAAASVTRRAGRRVAHA
CCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRLIVVSNRVAAGEDTRPSAGGLAVGVMDALKETGGVWFGWNGEIVDAPDTEPAIQQDG
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCEEECCCCCCCCHHCCC
NVTYATVGLNRRDYDQYYRGFSNATLWPVFHYRGDLARFDRQEYAGYLRVNAMLAKQLAA
CEEEEEECCCCCCHHHHHCCCCCCEEEEEHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHH
LLRPDDLIWVHDYHLLPFAHYLRELGVKNPIGFFLHIPFPSPDMLRLVPPHEELVKFMCA
HHCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEECCCHHHHHHHHHH
YDVAGFQTETDKQAFTDYIERRGIGAASDDGMLHAHGRVVKVAAYPIGVHPDAIAQAAVQ
HHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEEECCCCHHHHHHHHHH
YSARKPVKMLREALDGRKLVMSVDRLDYSKGLVERFQSFERMLANAPGWQGRVSLLQIAP
HHCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
PTRSDVKTYQDIRETLEGEAGRINGRFSQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVT
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELTGALLVNPYDLSQMAEALERALS
CCHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCHHHHHCCEEEECCCCHHHHHHHHHHHHC
MPLAERQARHEENLARLRVNDLSVWRDTFVADLRSVAAAASVTRRAGRRVAHA
CCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA