BacMap

Definition	Burkholderia sp. 383 chromosome 1, complete genome.
Accession	NC_007510
Length	3,694,126

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The map label for this gene is fabG [H]

Identifier: 78067088

GI number: 78067088

Start: 2718891

End: 2719724

Strand: Reverse

Name: fabG [H]

Synonym: Bcep18194_A5619

Alternate gene names: 78067088

Gene position: 2719724-2718891 (Counterclockwise)

Preceding gene: 78067099

Following gene: 78067087

Centisome position: 73.62

GC content: 71.82

Gene sequence:

>834_bases
ATGCGCCGGCGCGACGGGGCCGGGCCGGCACGTGTCGCCACCAAGGAATCGACGATGGATCTCGGCATCGAAGGAAAGAC
CGCGCTCGTGTGCGCGGCCAGCAAGGGGCTCGGTCGCGGCTGCGCGGAAGCGCTGGCCGCCGAGGGCGTGAACCTCGTGA
TCGTCGCGCGCACGCGCGACACGCTGGAGGAAACCGCGGAGGAGATCCGCGCCGGCGCGAACGTGTCGGTGACCGCGGTC
GCCTGCGACATCACGACGCCGGACGGGCGCGCGGCCGCGCTCGCCGCATGCCCGCAGCCGGACATTCTCGTGACGAATGC
CGGCGGCCCGCCGCCCGGCGATTTCCGCGATTTCTCGCACGACGACTGGATCCGCGCGCTCGAGTCGAACATGCTGACGC
CGATCGAGCTGATCCGCGCGACCCTCGACGGGATGATCGCGCGCGGCTTCGGCCGGATCGTCAACATCACGAGCTCGGCC
GTGAAGGCGCCGATCGACGTGCTCGCGCTGTCGAACGGCGCGCGCTCGGGGCTGACCGGCTTCGTCGCGGGGCTGTCGCG
CAAGGTCGCGGGGCAGGGCGTGACGATCAACAACCTGCTGCCGGGCCTGTTCGATACCGACCGGATCGCGACCACGCTCG
CCGCGTCGGCGAAGGCGCAGGGCGTGAGCGTCGACGAGATGCGCGCGCGGCGCACGAAGGACATCCCGGCCGGCCGCCTC
GGCACGCGCGAAGAGTTCGGCGCGGCGTGCGCGTTCCTGTGCAGCGTGCACGCCGGCTACATCACCGGGCAGAACTGGCT
GCTCGACGGCGGCTCGTATCCGGGCACGTTCTGA

Upstream 100 bases:

>100_bases
TTTTACCAAGGCGCGCCGCGTGATCCGGATAATATCGACGTCTTACGACAATCCGCGTGCCCGCGCCCGCCCGATTGCCC
GCCTGACCCGCCCGGGGTCC

Downstream 100 bases:

>100_bases
CGCGCGCACCGCCTTTCACGACAACAACCTGAAACGAAGGATCTGGAGATGAGCAAACCCCGCATCGCATTGATTGCGCA
CGACGCGAAGAAGGACGAGA

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MRRRDGAGPARVATKESTMDLGIEGKTALVCAASKGLGRGCAEALAAEGVNLVIVARTRDTLEETAEEIRAGANVSVTAV
ACDITTPDGRAAALAACPQPDILVTNAGGPPPGDFRDFSHDDWIRALESNMLTPIELIRATLDGMIARGFGRIVNITSSA
VKAPIDVLALSNGARSGLTGFVAGLSRKVAGQGVTINNLLPGLFDTDRIATTLAASAKAQGVSVDEMRARRTKDIPAGRL
GTREEFGAACAFLCSVHAGYITGQNWLLDGGSYPGTF

Sequences:

>Translated_277_residues
MRRRDGAGPARVATKESTMDLGIEGKTALVCAASKGLGRGCAEALAAEGVNLVIVARTRDTLEETAEEIRAGANVSVTAV
ACDITTPDGRAAALAACPQPDILVTNAGGPPPGDFRDFSHDDWIRALESNMLTPIELIRATLDGMIARGFGRIVNITSSA
VKAPIDVLALSNGARSGLTGFVAGLSRKVAGQGVTINNLLPGLFDTDRIATTLAASAKAQGVSVDEMRARRTKDIPAGRL
GTREEFGAACAFLCSVHAGYITGQNWLLDGGSYPGTF
>Mature_277_residues
MRRRDGAGPARVATKESTMDLGIEGKTALVCAASKGLGRGCAEALAAEGVNLVIVARTRDTLEETAEEIRAGANVSVTAV
ACDITTPDGRAAALAACPQPDILVTNAGGPPPGDFRDFSHDDWIRALESNMLTPIELIRATLDGMIARGFGRIVNITSSA
VKAPIDVLALSNGARSGLTGFVAGLSRKVAGQGVTINNLLPGLFDTDRIATTLAASAKAQGVSVDEMRARRTKDIPAGRL
GTREEFGAACAFLCSVHAGYITGQNWLLDGGSYPGTF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=267, Percent_Identity=27.7153558052434, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=27.2373540856031, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI226371731, Length=193, Percent_Identity=28.4974093264249, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI7705855, Length=200, Percent_Identity=27, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=25.2918287937743, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=25.6, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4503301, Length=260, Percent_Identity=28.0769230769231, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI66933014, Length=175, Percent_Identity=29.7142857142857, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI20149619, Length=203, Percent_Identity=29.064039408867, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI126723750, Length=270, Percent_Identity=25.1851851851852, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI126723191, Length=206, Percent_Identity=26.2135922330097, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=28.7179487179487, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=27.0992366412214, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=264, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=29.7297297297297, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=30.3846153846154, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=26.8774703557312, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=26.171875, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=22.3529411764706, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=26.4591439688716, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=25.5905511811024, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=25.6916996047431, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=27.0588235294118, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=28.8461538461538, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=27.6515151515151, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=259, Percent_Identity=28.957528957529, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=28.6792452830189, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=27.8810408921933, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=28.2442748091603, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=27.7153558052434, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=30.0380228136882, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=256, Percent_Identity=26.953125, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=28.3018867924528, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=27.3076923076923, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=27.4809160305344, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25152911, Length=191, Percent_Identity=30.3664921465969, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=26.3565891472868, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=28.4615384615385, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=28.7313432835821, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=26.2357414448669, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=27.2030651340996, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=26.7716535433071, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=29.9610894941634, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=30.7086614173228, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639444, Length=263, Percent_Identity=28.1368821292776, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=29.5719844357977, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21358495, Length=215, Percent_Identity=26.046511627907, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28682; Mature: 28682

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRDGAGPARVATKESTMDLGIEGKTALVCAASKGLGRGCAEALAAEGVNLVIVARTRD
CCCCCCCCCCCEEECCCCEECCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHH
TLEETAEEIRAGANVSVTAVACDITTPDGRAAALAACPQPDILVTNAGGPPPGDFRDFSH
HHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCC
DDWIRALESNMLTPIELIRATLDGMIARGFGRIVNITSSAVKAPIDVLALSNGARSGLTG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHCCEEEEEECCCCCCCHHH
FVAGLSRKVAGQGVTINNLLPGLFDTDRIATTLAASAKAQGVSVDEMRARRTKDIPAGRL
HHHHHHHHHCCCCEEHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCC
GTREEFGAACAFLCSVHAGYITGQNWLLDGGSYPGTF
CCHHHHHHHHHHHHHHHCCEEECCCEEEECCCCCCCC
>Mature Secondary Structure
MRRRDGAGPARVATKESTMDLGIEGKTALVCAASKGLGRGCAEALAAEGVNLVIVARTRD
CCCCCCCCCCCEEECCCCEECCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHH
TLEETAEEIRAGANVSVTAVACDITTPDGRAAALAACPQPDILVTNAGGPPPGDFRDFSH
HHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCC
DDWIRALESNMLTPIELIRATLDGMIARGFGRIVNITSSAVKAPIDVLALSNGARSGLTG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHCCEEEEEECCCCCCCHHH
FVAGLSRKVAGQGVTINNLLPGLFDTDRIATTLAASAKAQGVSVDEMRARRTKDIPAGRL
HHHHHHHHHCCCCEEHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCC
GTREEFGAACAFLCSVHAGYITGQNWLLDGGSYPGTF
CCHHHHHHHHHHHHHHHCCEEECCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]