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The map label for this gene is nuoH [H]

Identifier: 78067039

GI number: 78067039

Start: 2666808

End: 2667875

Strand: Reverse

Name: nuoH [H]

Synonym: Bcep18194_A5570

Alternate gene names: 78067039

Gene position: 2667875-2666808 (Counterclockwise)

Preceding gene: 78067040

Following gene: 78067038

Centisome position: 72.22

GC content: 63.01

Gene sequence:

>1068_bases
ATGAGCTTGTTCGATACGATCAACGCGGGCGGGTCCCAGCTTCTCGGCTTCGCATGGCCGACGGTGTGGGCAATCGTGCG
CATCCTCGTCGTCTCCGTCGTCATCCTGCTGTGCGTCGCGTACCTGATTCTGTGGGAACGCAAGCTGATCGGCTGGATGC
ACGTGCGTCTCGGCCCGAACCGCGTCGGCCCCGGCGGCTTGCTGCAGCCGATCGCCGACGTGCTGAAGCTGCTGCTGAAG
GAAGTCATTCAGCCGAGCGCCGCCAGCCGCTGGCTGTACCTGATCGCGCCGGTGATGACCGTCGTGCCGGCGTTCGCCGT
GTGGGCCGTGATCCCGTTCCAGGCCGAAGCGGTCCTCGCGAACGTCAACGCGGGCCTGCTGTACGCGATGGCGATCTCGT
CGATCGGCGTGTACGCGGTGATTCTCGCGGGCTGGGCATCGAACTCGAAGTACGCGTTCCTCGGCGCGATGCGCGCCGCG
GCACAGATGGTGTCGTACGAAATCTCGATGGGCTTCGCGCTGGTGCTGGTGCTGATGACGGCCGGCAGCCTGAACCTGTC
GGAAATCGTCGGTTCGCAGCAGCACGGCTTCTTCGCCGGCCACGGCGTGAACTTCCTGTCGTGGAACTGGCTGCCGCTCC
TGCCGGCGTTCGTCGTGTACTTCATCTCGGGCATCGCCGAAACGAACCGCCACCCGTTCGACGTGGTGGAAGGGGAGTCG
GAAATCGTTGCCGGTCACATGATCGATTACTCGGGTATGGCGTTCGCGCTGTTCTTCCTCGCCGAGTACATCAACATGAT
CGTGATCTCGGCGCTGACCGCGACGCTGTTCCTCGGCGGCTGGGATGCACCGTTCGAATTCCTGTCGTTCATTCCGGGCA
TCTTCTGGCTGGTGCTGAAGATATTCGCGCTGCTGTCGGTGTTCATCTGGGTTCGCGCGACGTTCCCGCGTTTCCGTTAC
GACCAGATCATGCGCTTGGGCTGGAAGGTGTTCCTGCCCGTCACGGTGGTCTGGGTGGTCGTGGTCGGCTTCTGGATGAT
GTCGCCGCTCAACATCTGGGTGAAGTAA

Upstream 100 bases:

>100_bases
CGCGAATCTTGCGGAGACCGTCGTTCGCGTGTCGGCGGCAACGCCTGCCGGCGCAGCGCTCGGCAGCCTGTCCGGTGAAC
TGGTGGTGGAGAAGGCGTAA

Downstream 100 bases:

>100_bases
TCGGACGAAATCATGAGCGCAATCCAACACTTCTTTAAGACCTTCTTCCTGACCGAGCTCCTGCAGGGGCTCGCGCTGAC
CGGCCGTTACACGTTCAAGC

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSLFDTINAGGSQLLGFAWPTVWAIVRILVVSVVILLCVAYLILWERKLIGWMHVRLGPNRVGPGGLLQPIADVLKLLLK
EVIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAEAVLANVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAA
AQMVSYEISMGFALVLVLMTAGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGES
EIVAGHMIDYSGMAFALFFLAEYINMIVISALTATLFLGGWDAPFEFLSFIPGIFWLVLKIFALLSVFIWVRATFPRFRY
DQIMRLGWKVFLPVTVVWVVVVGFWMMSPLNIWVK

Sequences:

>Translated_355_residues
MSLFDTINAGGSQLLGFAWPTVWAIVRILVVSVVILLCVAYLILWERKLIGWMHVRLGPNRVGPGGLLQPIADVLKLLLK
EVIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAEAVLANVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAA
AQMVSYEISMGFALVLVLMTAGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGES
EIVAGHMIDYSGMAFALFFLAEYINMIVISALTATLFLGGWDAPFEFLSFIPGIFWLVLKIFALLSVFIWVRATFPRFRY
DQIMRLGWKVFLPVTVVWVVVVGFWMMSPLNIWVK
>Mature_354_residues
SLFDTINAGGSQLLGFAWPTVWAIVRILVVSVVILLCVAYLILWERKLIGWMHVRLGPNRVGPGGLLQPIADVLKLLLKE
VIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAEAVLANVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAA
QMVSYEISMGFALVLVLMTAGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGESE
IVAGHMIDYSGMAFALFFLAEYINMIVISALTATLFLGGWDAPFEFLSFIPGIFWLVLKIFALLSVFIWVRATFPRFRYD
QIMRLGWKVFLPVTVVWVVVVGFWMMSPLNIWVK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=302, Percent_Identity=43.7086092715232, Blast_Score=257, Evalue=1e-68,
Organism=Escherichia coli, GI1788618, Length=319, Percent_Identity=41.0658307210031, Blast_Score=261, Evalue=5e-71,
Organism=Escherichia coli, GI1789077, Length=285, Percent_Identity=24.2105263157895, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 39303; Mature: 39172

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFDTINAGGSQLLGFAWPTVWAIVRILVVSVVILLCVAYLILWERKLIGWMHVRLGPN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
RVGPGGLLQPIADVLKLLLKEVIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAEAVLA
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMT
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGES
CCCCCHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCC
EIVAGHMIDYSGMAFALFFLAEYINMIVISALTATLFLGGWDAPFEFLSFIPGIFWLVLK
CEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IFALLSVFIWVRATFPRFRYDQIMRLGWKVFLPVTVVWVVVVGFWMMSPLNIWVK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure 
SLFDTINAGGSQLLGFAWPTVWAIVRILVVSVVILLCVAYLILWERKLIGWMHVRLGPN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
RVGPGGLLQPIADVLKLLLKEVIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAEAVLA
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NVNAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMT
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGES
CCCCCHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCC
EIVAGHMIDYSGMAFALFFLAEYINMIVISALTATLFLGGWDAPFEFLSFIPGIFWLVLK
CEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IFALLSVFIWVRATFPRFRYDQIMRLGWKVFLPVTVVWVVVVGFWMMSPLNIWVK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA