Click here to switch to the map view.

The map label for this gene is nuoN [H]

Identifier: 78067033

GI number: 78067033

Start: 2660147

End: 2661616

Strand: Reverse

Name: nuoN [H]

Synonym: Bcep18194_A5564

Alternate gene names: 78067033

Gene position: 2661616-2660147 (Counterclockwise)

Preceding gene: 78067034

Following gene: 78067032

Centisome position: 72.05

GC content: 63.47

Gene sequence:

>1470_bases
ATGAACGCTCCTATGAATGTCCTGTTGCCTGACGCGCTGGTGATGGCCGCCATCGTCGTCGCATGGCTGAACGACACCTT
TACCGGTGCTTCCGGCCGCCGCCTGACTTATCTGATCGCGGTCGTATCGTCGGTCGTCGCCGGCGTGTGGTTCGCGGTGC
AGGCACTCGACCCGCAGCAGTACTACTTCTTCTCGAAGATGGTCGTCGTCGACTCGTTCGCGAGCACGATGAAGGCTGTC
GTGTCGTTCGGTTTCGCGGTCTCGCTCGTCTATTCGCGCAAGTACCTCGAAGATCGCGACATGTTCCGCGGTGACGTGTT
CCTGCTCGGCATGTTCTCGCTGCTCGGTCAGCTGGTCATGGTGTCGGGCAACAACTTCCTGACGCTGTACCTCGGTCTCG
AACTGATGTCGCTGTCGCTGTACGCCGTCATCGCGCTGCGCCGCGACGCCGCGCAGTCGAGCGAAGCTGCGATGAAGTAC
TACGTGCTGGGCGCGCTCGCATCGGGCTTCGTGCTGTATGGCATCTCGATGCTCTACGGCGCGACCGGCTCGCTCGAGCT
GGGCGAGGTGTACAAGGCGGTTAGCGGCAACACCGACGCAGCCGTGCTGATGTTCGGCGTGGTCTTCATCGTCGCCGGTA
TCGCGTTCAAGCTCGGCGCCGTGCCGTTCCACATGTGGGTGCCGGACGTCTACCAGGGCGCACCGACCGCAATGACGCTG
TTCGTCGGCGGCGGCCCGAAGGTTGCCGCGTTCGCGTGGGGCCTGCGCTTCCTGGTGATGGGCCTGCTGCCGCTCGCACA
GAACTGGCAGACCGCGCTCGTGATCCTGGCCGCACTGTCGCTGATCGTCGGCAACATCACGGGTATCGTCCAGCGCAACA
TCAAGCGGATGCTCGCGTACTCGGCGATCTCGAACATGGGCTTCGTGCTGCTCGGCCTGCTCGCGGGCATCGTGAAGGGC
GACGCAACGGCACCGGCGAACGCATACAGCTCGGCGATGTTCTATGCGATCGTCTACCTGATCACGACGCTCGGCTCGTT
CGGCGTGGTGATGCTGCTCGCACGCCGCGATTTCGAAGCCGAGACGATCGACGACTTCAAGGGCCTCAACAAGCGCAGCC
CGGTGTTCGCGTTCGTGATGATGGTCATGATGTTCTCGCTGGCTGGTATTCCGCCGACCGTCGGCTTCTACGCGAAGCTC
GCCGTGCTCGAGGCGACCGTCAACGCGGGTCTCACGTGGCTGGCCGTGCTGGCCGTGATCACGTCGCTGTTCGGCGCGTT
CTACTACCTGCGCATCGTGAAGCTGATGTACTTCGATGCACCGCAGGATACGACCCCGATCTCGGGCGATTTCTGCAAGC
GCACGATCCTCGTGCTGAACGGCCTGGCGGTCGTGGTGCTCGGCCTGATCCCGAGCCCGCTGCTGACGGCCTGCCTGCAG
GCAATTCGTCACACGCTGCCGCCGCTGTAA

Upstream 100 bases:

>100_bases
CACCGACGTGATGCACGTTTCCGTGGAAAACCTCCTCTCCCATGTCGCGCAGTCGAAGCTGCCGCTGGCCCAGTAATCGC
GAGCGGAGGAACTCAAGATC

Downstream 100 bases:

>100_bases
TGTCGGCAGCCGGCTGGTTTATCGTGCTGTTGGCGCTCGTCTGCGCCAACCTGCCGTTCCTGAACCAACGCCTCTTCGCC
GTCGTGCCGTTCGGCACGGC

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MNAPMNVLLPDALVMAAIVVAWLNDTFTGASGRRLTYLIAVVSSVVAGVWFAVQALDPQQYYFFSKMVVVDSFASTMKAV
VSFGFAVSLVYSRKYLEDRDMFRGDVFLLGMFSLLGQLVMVSGNNFLTLYLGLELMSLSLYAVIALRRDAAQSSEAAMKY
YVLGALASGFVLYGISMLYGATGSLELGEVYKAVSGNTDAAVLMFGVVFIVAGIAFKLGAVPFHMWVPDVYQGAPTAMTL
FVGGGPKVAAFAWGLRFLVMGLLPLAQNWQTALVILAALSLIVGNITGIVQRNIKRMLAYSAISNMGFVLLGLLAGIVKG
DATAPANAYSSAMFYAIVYLITTLGSFGVVMLLARRDFEAETIDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKL
AVLEATVNAGLTWLAVLAVITSLFGAFYYLRIVKLMYFDAPQDTTPISGDFCKRTILVLNGLAVVVLGLIPSPLLTACLQ
AIRHTLPPL

Sequences:

>Translated_489_residues
MNAPMNVLLPDALVMAAIVVAWLNDTFTGASGRRLTYLIAVVSSVVAGVWFAVQALDPQQYYFFSKMVVVDSFASTMKAV
VSFGFAVSLVYSRKYLEDRDMFRGDVFLLGMFSLLGQLVMVSGNNFLTLYLGLELMSLSLYAVIALRRDAAQSSEAAMKY
YVLGALASGFVLYGISMLYGATGSLELGEVYKAVSGNTDAAVLMFGVVFIVAGIAFKLGAVPFHMWVPDVYQGAPTAMTL
FVGGGPKVAAFAWGLRFLVMGLLPLAQNWQTALVILAALSLIVGNITGIVQRNIKRMLAYSAISNMGFVLLGLLAGIVKG
DATAPANAYSSAMFYAIVYLITTLGSFGVVMLLARRDFEAETIDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKL
AVLEATVNAGLTWLAVLAVITSLFGAFYYLRIVKLMYFDAPQDTTPISGDFCKRTILVLNGLAVVVLGLIPSPLLTACLQ
AIRHTLPPL
>Mature_489_residues
MNAPMNVLLPDALVMAAIVVAWLNDTFTGASGRRLTYLIAVVSSVVAGVWFAVQALDPQQYYFFSKMVVVDSFASTMKAV
VSFGFAVSLVYSRKYLEDRDMFRGDVFLLGMFSLLGQLVMVSGNNFLTLYLGLELMSLSLYAVIALRRDAAQSSEAAMKY
YVLGALASGFVLYGISMLYGATGSLELGEVYKAVSGNTDAAVLMFGVVFIVAGIAFKLGAVPFHMWVPDVYQGAPTAMTL
FVGGGPKVAAFAWGLRFLVMGLLPLAQNWQTALVILAALSLIVGNITGIVQRNIKRMLAYSAISNMGFVLLGLLAGIVKG
DATAPANAYSSAMFYAIVYLITTLGSFGVVMLLARRDFEAETIDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKL
AVLEATVNAGLTWLAVLAVITSLFGAFYYLRIVKLMYFDAPQDTTPISGDFCKRTILVLNGLAVVVLGLIPSPLLTACLQ
AIRHTLPPL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=329, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI145693160, Length=489, Percent_Identity=33.5378323108384, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI1788614, Length=412, Percent_Identity=25, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788827, Length=329, Percent_Identity=26.4437689969605, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788831, Length=306, Percent_Identity=25.8169934640523, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI2367154, Length=148, Percent_Identity=27.7027027027027, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52615; Mature: 52615

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCC
>Mature Secondary Structure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HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA