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The map label for this gene is pbpG [H]

Identifier: 78066908

GI number: 78066908

Start: 2506945

End: 2508111

Strand: Reverse

Name: pbpG [H]

Synonym: Bcep18194_A5439

Alternate gene names: 78066908

Gene position: 2508111-2506945 (Counterclockwise)

Preceding gene: 78066910

Following gene: 78066906

Centisome position: 67.89

GC content: 65.21

Gene sequence:

>1167_bases
ATGAAAGCCGAATCGTTTTCACCGCGCAGATTGTTGCAGAGCATGACGCTCGGCACGGCTGTGTCGATCGCAGTCGCCTT
GCTGGCGACCACCGCGACCGTCGCGCCCGCTGACGCCTTTGCCGCCACTGCGAAGACCCAACAAGCCGCCAAGAAAAAGG
CTGTCGCTCCTGCTTCGTCCGCGAAGAAGAAGTCGGCCAAGGCCAGCTCCGACAAATCCGCGAAAGTCGCGGCCGCCGAC
GCGCCGCGCGCGAAGGCATCGCGCAAGCGCGTGACGCTCGCGTCGAACGTGCATGGCGGCCATCACGGCGCAGTGCGCAA
GGTCGCGTTCCAGCCGCGCCGGCCGACCGTCGGCCAGGCGTTCGGCCTGCACGACACGCCCGACGCGCTCGCGCTGCGTT
CGAGCGTCGCGTATGTCGTCGACCAGAATTCGGGCGAGCCGCTGTTCGACAAGAATTCGCACGCCGTCGTGCCGATCGCG
TCGATCTCGAAGCTGATGACGGCGATGGTCGTGCTCGACTCGAAGACGCCGATGACCGACCAGATCGAAGTCACCGACGA
AGACCGCGACTACGAGAAGGGCACGGGCTCGCGCCTGTCGGTCGGCTCGGTGCTGTCGCGTGAAGACATGCTGCACATCG
CGCTGATGGCGTCGGAAAACCGCGCGGCCGCTGCGCTGTCGCGTTACTACGCGGGTGGTCGTCCGGCGTTCATCGCCGCG
ATGAACGCGAAGGCGAAGTCGCTCGGCATGACCGATACGCACTTCGAGAATTCGACGGGTCTGTCGAGCTCGAACGTGTC
GAGCGCGCGCGACCTCGTGAAGATGGTCAATGCGGCGTACCAGTACCCGATGATTCGTCAGTTCTCGACCGATCGCACCT
ACGAGGTGTACACGGGCAAGCGCAACCTGGTCTACAACAGCACGAACGCGCTGATCCGCGGCAATGGCTCGTGGGACATC
GGTCTGCAGAAGACGGGCTTCATCAACGAAGCCGGCGAATGTCTCGTGATGCAGGCGACGATCCACGGCAAGCCGATGGT
GATGGTGCTGCTGGATTCGTTCGGCAAGTATTCGCGCTTCGCCGATGCGGCGCGCCTGCGCAACTGGCTCGATGCCGGCG
GCGGCGAGCGCCTGACGGCGGCCAACACGCCGGCCGGCGGGACCTGA

Upstream 100 bases:

>100_bases
CATTCCGGTTTAACGACGATCGGTAAGTGCCTAATATTGCTCTTTTTTTCAGCTTTAACTACACTTGCGGAAACCTCCCG
CCCGCTTTGTCCAGACCCCA

Downstream 100 bases:

>100_bases
TCGCACGAAGGCGTGGCGGTTCGCCGCCGCGCCGACGGCTAAAAAAAAGCCCCGCAATCGCGGGGCTTTTTCATTGGGTG
CGCGGGAGCGGCTTACGCCT

Product: murein-DD-endopeptidase

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 5; PBP-5 [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKAESFSPRRLLQSMTLGTAVSIAVALLATTATVAPADAFAATAKTQQAAKKKAVAPASSAKKKSAKASSDKSAKVAAAD
APRAKASRKRVTLASNVHGGHHGAVRKVAFQPRRPTVGQAFGLHDTPDALALRSSVAYVVDQNSGEPLFDKNSHAVVPIA
SISKLMTAMVVLDSKTPMTDQIEVTDEDRDYEKGTGSRLSVGSVLSREDMLHIALMASENRAAAALSRYYAGGRPAFIAA
MNAKAKSLGMTDTHFENSTGLSSSNVSSARDLVKMVNAAYQYPMIRQFSTDRTYEVYTGKRNLVYNSTNALIRGNGSWDI
GLQKTGFINEAGECLVMQATIHGKPMVMVLLDSFGKYSRFADAARLRNWLDAGGGERLTAANTPAGGT

Sequences:

>Translated_388_residues
MKAESFSPRRLLQSMTLGTAVSIAVALLATTATVAPADAFAATAKTQQAAKKKAVAPASSAKKKSAKASSDKSAKVAAAD
APRAKASRKRVTLASNVHGGHHGAVRKVAFQPRRPTVGQAFGLHDTPDALALRSSVAYVVDQNSGEPLFDKNSHAVVPIA
SISKLMTAMVVLDSKTPMTDQIEVTDEDRDYEKGTGSRLSVGSVLSREDMLHIALMASENRAAAALSRYYAGGRPAFIAA
MNAKAKSLGMTDTHFENSTGLSSSNVSSARDLVKMVNAAYQYPMIRQFSTDRTYEVYTGKRNLVYNSTNALIRGNGSWDI
GLQKTGFINEAGECLVMQATIHGKPMVMVLLDSFGKYSRFADAARLRNWLDAGGGERLTAANTPAGGT
>Mature_388_residues
MKAESFSPRRLLQSMTLGTAVSIAVALLATTATVAPADAFAATAKTQQAAKKKAVAPASSAKKKSAKASSDKSAKVAAAD
APRAKASRKRVTLASNVHGGHHGAVRKVAFQPRRPTVGQAFGLHDTPDALALRSSVAYVVDQNSGEPLFDKNSHAVVPIA
SISKLMTAMVVLDSKTPMTDQIEVTDEDRDYEKGTGSRLSVGSVLSREDMLHIALMASENRAAAALSRYYAGGRPAFIAA
MNAKAKSLGMTDTHFENSTGLSSSNVSSARDLVKMVNAAYQYPMIRQFSTDRTYEVYTGKRNLVYNSTNALIRGNGSWDI
GLQKTGFINEAGECLVMQATIHGKPMVMVLLDSFGKYSRFADAARLRNWLDAGGGERLTAANTPAGGT

Specific function: Cell wall formation [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=244, Percent_Identity=50.8196721311475, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI87082022, Length=258, Percent_Identity=27.906976744186, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787062, Length=282, Percent_Identity=28.3687943262411, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786851, Length=245, Percent_Identity=25.7142857142857, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 41164; Mature: 41164

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAESFSPRRLLQSMTLGTAVSIAVALLATTATVAPADAFAATAKTQQAAKKKAVAPASS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHH
AKKKSAKASSDKSAKVAAADAPRAKASRKRVTLASNVHGGHHGAVRKVAFQPRRPTVGQA
HHHHHCCCCCCCCCEEEECCCCCHHHCCCEEEEECCCCCCCCCHHHHEEECCCCCCCCCC
FGLHDTPDALALRSSVAYVVDQNSGEPLFDKNSHAVVPIASISKLMTAMVVLDSKTPMTD
CCCCCCCHHHHHHCCEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCC
QIEVTDEDRDYEKGTGSRLSVGSVLSREDMLHIALMASENRAAAALSRYYAGGRPAFIAA
EEEECCCCCCCCCCCCCEEEHHHHHCCCCEEEEEEEECCCHHHHHHHHHHCCCCCEEEEE
MNAKAKSLGMTDTHFENSTGLSSSNVSSARDLVKMVNAAYQYPMIRQFSTDRTYEVYTGK
ECCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEECC
RNLVYNSTNALIRGNGSWDIGLQKTGFINEAGECLVMQATIHGKPMVMVLLDSFGKYSRF
CEEEEECCCEEEECCCCEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEEEHHCCHHHHH
ADAARLRNWLDAGGGERLTAANTPAGGT
HHHHHHHHHHHCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MKAESFSPRRLLQSMTLGTAVSIAVALLATTATVAPADAFAATAKTQQAAKKKAVAPASS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHH
AKKKSAKASSDKSAKVAAADAPRAKASRKRVTLASNVHGGHHGAVRKVAFQPRRPTVGQA
HHHHHCCCCCCCCCEEEECCCCCHHHCCCEEEEECCCCCCCCCHHHHEEECCCCCCCCCC
FGLHDTPDALALRSSVAYVVDQNSGEPLFDKNSHAVVPIASISKLMTAMVVLDSKTPMTD
CCCCCCCHHHHHHCCEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCC
QIEVTDEDRDYEKGTGSRLSVGSVLSREDMLHIALMASENRAAAALSRYYAGGRPAFIAA
EEEECCCCCCCCCCCCCEEEHHHHHCCCCEEEEEEEECCCHHHHHHHHHHCCCCCEEEEE
MNAKAKSLGMTDTHFENSTGLSSSNVSSARDLVKMVNAAYQYPMIRQFSTDRTYEVYTGK
ECCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEECC
RNLVYNSTNALIRGNGSWDIGLQKTGFINEAGECLVMQATIHGKPMVMVLLDSFGKYSRF
CEEEEECCCEEEECCCCEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEEEHHCCHHHHH
ADAARLRNWLDAGGGERLTAANTPAGGT
HHHHHHHHHHHCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]