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The map label for this gene is trpS [H]

Identifier: 78066872

GI number: 78066872

Start: 2470960

End: 2472162

Strand: Reverse

Name: trpS [H]

Synonym: Bcep18194_A5403

Alternate gene names: 78066872

Gene position: 2472162-2470960 (Counterclockwise)

Preceding gene: 78066873

Following gene: 78066871

Centisome position: 66.92

GC content: 64.26

Gene sequence:

>1203_bases
ATGTTCCCTGAACGTATTTTCTCCGGCATGCGACCCACCGGGTCGCTGCACCTCGGTCACTACCACGGCGTGCTGAAAAA
CTGGGTGAAACTGCAGTCCGAGTACCCGTGCTTCTTCTGCGTCGTCGACTGGCATGCGTTGACGACGCATTACGAGACTC
CCGAGGTCATCGAGAAGAACGTATGGGACGTGCTGATCGACTGGCTCGCGTCCGGCATCGATCCGGCGCAGGCCACGCTG
TTCATCCAGAGCAAGGTGCCCGAGCATGCGGAACTCGCGCTGCTGCTCGGCATGAGCACGCCGCTCGGCTGGCTCGAACG
CGTGCCGACCTACAAGGAGCAGATGGAGAAGCTGAAGGACAAGGATCTGTCAACGTACGGCTTCCTCGGCTACCCGGTGC
TGATGGCGGCCGACATCCTGCTGTATCGCGGCTCGCTCGTGCCGGTCGGTGAAGACCAGGTGCCGCACGTCGAGATGACG
CGCGAGATCGCGCGCCGCTTCAACTACCTGTATGGTCGCGAGCCGGGCTTCGAGGAAAAGGCGCTCGACGCCGCGAAGAA
ACTCGGCGGCAAGCGCGCGAAGCTCTATCACGAGCTGCGCAACGCGTATCAGCAGGAGGGCGACGACGAGGCGCTCGAAC
AGGCGCGCGCGATGCTGCAGGAATCGCAGAGCCTGTCGATGAGCGACCGCGAGCGCCTGTTCGGCTATCTCGAAGGCGCG
CGCAAGATCATCCTGGTCGAGCCGCAGGCGCTCCTGACCGAAGCATCGCGGATGCCGGGCCTGGACGGCCAGAAGATGTC
CAAGTCGTACGGCAACACGATCGGCCTGCGTGAAGACGCCGAGACGATCACGAAGAAGGTCCGCACGATGCCGACCGATC
CCGCGCGTGTGCGCCGCACTGATCCGGGCGATCCCGACAAGTGCCCGGTGTGGCAGCTGCACCAGGTCTATACCGACGAA
GCGACGCACGACTGGGTGCAGAAGGGCTGCCGCTCGGCAGGCATCGGCTGTCTCGACTGCAAGCAGCCGGTCGTCGAAGG
CATCCTGCGCGAACAGCAGCCGATGCTCGAGCGCGCACAGAAGTACATGGACGATCCGTCGCTGCTGCGCGCGATCGTCG
CGGACGGTTGCGACAAGGCGCGCAAGTACGCGACGGAAACGATGCGCGACGTGCGCGACGCGATGGGCCTGTCGTACAAC
TGA

Upstream 100 bases:

>100_bases
GCGTGCTGACGAACTTCTGGCTGCGCCCGCTCGTCAACGTCGGCTACGCCGTCCTGAGCGCCATCCTGTCCCCATTCGCC
TCGCTTCTCTAACGACAATC

Downstream 100 bases:

>100_bases
TCGACCGCATGAACGCATCCGTCATGACCGCCGCGGGCGGCCACGTCGCGCAGGCCGAGCCGTCGCGCTGGGTCGCGCAA
TGGTCGCGGCTCGTGCCGCC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MFPERIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWDVLIDWLASGIDPAQATL
FIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQMEKLKDKDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMT
REIARRFNYLYGREPGFEEKALDAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRTDPGDPDKCPVWQLHQVYTDE
ATHDWVQKGCRSAGIGCLDCKQPVVEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARKYATETMRDVRDAMGLSYN

Sequences:

>Translated_400_residues
MFPERIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWDVLIDWLASGIDPAQATL
FIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQMEKLKDKDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMT
REIARRFNYLYGREPGFEEKALDAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRTDPGDPDKCPVWQLHQVYTDE
ATHDWVQKGCRSAGIGCLDCKQPVVEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARKYATETMRDVRDAMGLSYN
>Mature_400_residues
MFPERIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWDVLIDWLASGIDPAQATL
FIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQMEKLKDKDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMT
REIARRFNYLYGREPGFEEKALDAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRTDPGDPDKCPVWQLHQVYTDE
ATHDWVQKGCRSAGIGCLDCKQPVVEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARKYATETMRDVRDAMGLSYN

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=190, Percent_Identity=41.5789473684211, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI41352700, Length=170, Percent_Identity=43.5294117647059, Blast_Score=142, Evalue=7e-34,
Organism=Escherichia coli, GI1789786, Length=167, Percent_Identity=46.7065868263473, Blast_Score=166, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71982800, Length=176, Percent_Identity=35.7954545454545, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71982793, Length=176, Percent_Identity=35.7954545454545, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6320474, Length=184, Percent_Identity=36.4130434782609, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24666151, Length=172, Percent_Identity=42.4418604651163, Blast_Score=152, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 45476; Mature: 45476

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPERIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKN
CCHHHHHCCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCCCCHHHHHHH
VWDVLIDWLASGIDPAQATLFIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQMEKLKD
HHHHHHHHHHCCCCHHHHEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHH
KDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMTREIARRFNYLYGREPGFEEK
CCCCHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
ALDAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRT
CEEEEECCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHCCCC
DPGDPDKCPVWQLHQVYTDEATHDWVQKGCRSAGIGCLDCKQPVVEGILREQQPMLERAQ
CCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KYMDDPSLLRAIVADGCDKARKYATETMRDVRDAMGLSYN
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFPERIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKN
CCHHHHHCCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCCCCHHHHHHH
VWDVLIDWLASGIDPAQATLFIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQMEKLKD
HHHHHHHHHHCCCCHHHHEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHH
KDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMTREIARRFNYLYGREPGFEEK
CCCCHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
ALDAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRT
CEEEEECCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHCCCC
DPGDPDKCPVWQLHQVYTDEATHDWVQKGCRSAGIGCLDCKQPVVEGILREQQPMLERAQ
CCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KYMDDPSLLRAIVADGCDKARKYATETMRDVRDAMGLSYN
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]