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The map label for this gene is btuE [C]

Identifier: 78066813

GI number: 78066813

Start: 2403045

End: 2403524

Strand: Reverse

Name: btuE [C]

Synonym: Bcep18194_A5344

Alternate gene names: 78066813

Gene position: 2403524-2403045 (Counterclockwise)

Preceding gene: 78066815

Following gene: 78066806

Centisome position: 65.06

GC content: 63.33

Gene sequence:

>480_bases
ATGTCCACCCTGTATTCGTTCAGCGCAGAGACGCTTGCCGGCGCGCCGGCCTCGCTCGACGCGTATCGCGGCAAGGTGCT
GCTGATCGTCAACACCGCGAGCGAGTGTGGTTTCACGCCGCAGTACGCGGGCCTGCAGAAGCTGTACGACCAGTACGCGG
CGCGCGGTTTCTATGTGCTCGGCTTCCCGTGCAACCAGTTCGGCAAGCAGGAGCCCGGCGACGCCGCGCAAATCGGCGCG
TTCTGCGAGCGCAATTACGGCGTCACGTTCCCGATGTTCGCGAAGATCGACGTGAAGGGCGACCATGCGCATCCGCTGTA
CCGCTACCTGACCGACGAGGCGCCCGGCATTCTCGGCCTCAAGGCGATCAAGTGGAATTTCACGAAATTCCTGGTCGATC
GCGAAGGGCGCATCGTCAAGCGCTACGCGCCGTCGACCAAGCCGGACGAAATCGCCGCGGATATCGACAAGCTGCTGTGA

Upstream 100 bases:

>100_bases
GCGCGCCGCTCGCGCCGGGCATTGGCCGTTCGGCGGATGCCGCAACGGGGCAATTTCGCCTAGACTCCACGTCGATCCGG
TTTCGTAAAAGGAGTGCCCG

Downstream 100 bases:

>100_bases
CGGCGGCCGGCGGCGTTCGCGGCGCCGGTGCGGATCGCACGGCCGCCGCCGCCGTCCCGGCCGTTAGAGGATCGGTGCGA
ACAGCCGCGCGACGTGCATC

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSTLYSFSAETLAGAPASLDAYRGKVLLIVNTASECGFTPQYAGLQKLYDQYAARGFYVLGFPCNQFGKQEPGDAAQIGA
FCERNYGVTFPMFAKIDVKGDHAHPLYRYLTDEAPGILGLKAIKWNFTKFLVDREGRIVKRYAPSTKPDEIAADIDKLL

Sequences:

>Translated_159_residues
MSTLYSFSAETLAGAPASLDAYRGKVLLIVNTASECGFTPQYAGLQKLYDQYAARGFYVLGFPCNQFGKQEPGDAAQIGA
FCERNYGVTFPMFAKIDVKGDHAHPLYRYLTDEAPGILGLKAIKWNFTKFLVDREGRIVKRYAPSTKPDEIAADIDKLL
>Mature_158_residues
STLYSFSAETLAGAPASLDAYRGKVLLIVNTASECGFTPQYAGLQKLYDQYAARGFYVLGFPCNQFGKQEPGDAAQIGAF
CERNYGVTFPMFAKIDVKGDHAHPLYRYLTDEAPGILGLKAIKWNFTKFLVDREGRIVKRYAPSTKPDEIAADIDKLL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=47.4358974358974, Blast_Score=140, Evalue=5e-34,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=47.4358974358974, Blast_Score=139, Evalue=8e-34,
Organism=Homo sapiens, GI15618997, Length=157, Percent_Identity=43.9490445859873, Blast_Score=134, Evalue=2e-32,
Organism=Homo sapiens, GI192455698, Length=160, Percent_Identity=40, Blast_Score=134, Evalue=3e-32,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=48.0916030534351, Blast_Score=115, Evalue=1e-26,
Organism=Homo sapiens, GI41406084, Length=186, Percent_Identity=37.0967741935484, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI4557629, Length=178, Percent_Identity=35.3932584269663, Blast_Score=96, Evalue=1e-20,
Organism=Homo sapiens, GI6006001, Length=178, Percent_Identity=34.8314606741573, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=31.4917127071823, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI33186887, Length=177, Percent_Identity=32.2033898305085, Blast_Score=82, Evalue=1e-16,
Organism=Homo sapiens, GI41406082, Length=70, Percent_Identity=52.8571428571429, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1788003, Length=167, Percent_Identity=40.1197604790419, Blast_Score=145, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=46.25, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=44.375, Blast_Score=145, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI193210707, Length=162, Percent_Identity=44.4444444444444, Blast_Score=134, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=41.1392405063291, Blast_Score=131, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17550320, Length=181, Percent_Identity=33.1491712707182, Blast_Score=109, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI193209493, Length=181, Percent_Identity=33.7016574585635, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=40, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=40.7894736842105, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193210709, Length=72, Percent_Identity=50, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319721, Length=158, Percent_Identity=51.8987341772152, Blast_Score=186, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=50.9433962264151, Blast_Score=185, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=45.9119496855346, Blast_Score=161, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=46.875, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=46.875, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=46.875, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=44.0251572327044, Blast_Score=129, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17588; Mature: 17457

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLYSFSAETLAGAPASLDAYRGKVLLIVNTASECGFTPQYAGLQKLYDQYAARGFYVL
CCCCCCCCCHHHCCCCCCCHHHCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCEEEE
GFPCNQFGKQEPGDAAQIGAFCERNYGVTFPMFAKIDVKGDHAHPLYRYLTDEAPGILGL
ECCHHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHCCCCCEEEE
KAIKWNFTKFLVDREGRIVKRYAPSTKPDEIAADIDKLL
EEEEECCEEEEECCCCCEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
STLYSFSAETLAGAPASLDAYRGKVLLIVNTASECGFTPQYAGLQKLYDQYAARGFYVL
CCCCCCCCHHHCCCCCCCHHHCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCEEEE
GFPCNQFGKQEPGDAAQIGAFCERNYGVTFPMFAKIDVKGDHAHPLYRYLTDEAPGILGL
ECCHHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHCCCCCEEEE
KAIKWNFTKFLVDREGRIVKRYAPSTKPDEIAADIDKLL
EEEEECCEEEEECCCCCEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]