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The map label for this gene is ppsA [H]

Identifier: 78066781

GI number: 78066781

Start: 2362811

End: 2365213

Strand: Reverse

Name: ppsA [H]

Synonym: Bcep18194_A5312

Alternate gene names: 78066781

Gene position: 2365213-2362811 (Counterclockwise)

Preceding gene: 78066783

Following gene: 78066780

Centisome position: 64.03

GC content: 63.34

Gene sequence:

>2403_bases
ATGACTAACGCAGCAAACGTCGCAAAGGACCAGGCGTATGTAATTCCGTTCGAGCAGTTGCGGATGACCGATGTGGAGAT
CGTCGGCGGCAAGAATGCGTCGCTTGGCGAAATGATCAGCCAGCTTTCCGAAGCAGGCGTTCGCGTACCCACCGGTTTCG
CCACGACCGCGCTCGCGTTCCGCGATTTCCTCACGCACAACGACCTTACCGACCGCATCGCCAAGCGTCTCGAGTCGCTC
GACATCGACGACGTGAAGGCGCTCGCCGAAGCCGGGGCCGAAATCCGCAAGTGGATCGTCGATGCGCCGATGCAGGCACG
TCTCGAGCAGGAAATCCGTGAACAGTTCGAAATCCTGAAGAACAGCTCGCCGGGCGAGCTGTCGTTCGCCGTGCGTTCGT
CCGCGACCGCGGAAGACCTGCCCGACGCATCGTTCGCCGGCCAGCAGGAGTCGTACCTGAACGTCGTCGGCATCGAAGAC
GTGCTCGACCGCATGAAGCACGTGTTCGCGTCGCTGTACAACGACCGCGCGATCTCGTATCGCGTGCACAAGGGCTTCAC
GCACGCGGAAGTCGCCCTGTCGGCCGGCGTGCAGCGCATGGTCCGCTCGGACGTCGGCGCCGCCGGCGTGATGTTCACGA
TCGACACCGAATCGGGCTTCAAGGACGCCGTGTTCATCACGTCGAGCTACGGCCTGGGCGAAACCGTCGTGCAGGGCGCA
GTGAACCCGGACGAGTTCTATGTGTTCAAGACGACGCTCGCACAGGACAAGTACCCGATCATCCGCCGCTCGATCGGCTC
GAAGCTGATCAAGATGGAATTCACGCAGCCGGGCGAGCCGGGCCGCGTGAAGACGGTCGACGTGCCGCACGAGCAGCGCA
ACCGCTACTCGATCACCGACGAAGACGTGATCGAGCTGGCGAAGTACGCGGTCATCATCGAGAAGCACTACCAGCGTCCG
ATGGACATCGAGTGGGGCAAGGACGGCCGCGACGGCAAGATCTTCATCCTGCAGGCACGCCCGGAAACCGTGAAGAGCCA
GGCGACCGGCAAGGCCGAACAGCGCTTCAAGCTGAAGGGCCAGTCGCAGGTGCTCGCGACGGGTCGTGCGATCGGCCAGA
AGATCGGTGCGGGCCCCGTGCGCGTGATCCAGGATCCGTCGGAAATGGAACGCGTGCAGCCGGGCGACGTGCTGGTGGCC
GACATGACCGACCCGAACTGGGAGCCGGTGATGAAGCGTGCAGCCGCGATCGTCACGAACCGTGGCGGCCGCACCTGCCA
CGCGGCGATCATCGCGCGTGAACTCGGCGTGCCGGCAGTCGTCGGCTGCGGCGATGCGACCGACATCCTGAAGGACGGCG
CGCTGGTTACCGTGTCGTGCGCGGAAGGCGACGAAGGCAAGATCTACGACGGCCTGCTCGAGACGGAAGTCACGGAAGTG
CAGCGCGGCGAACTGCCGGAAATCCCGGTCAAGATCATGATGAACGTCGGCAACCCGCAGCTCGCGTTCGACTTCTCGCA
ACTGCCGAACGGCGGCGTGGGTCTCGCGCGTCTCGAGTTCATCATCAACAACAACATCGGCGTTCACCCGAAGGCGATCC
TCGAGTACCCGAACATCGACCAGGACCTGAAGAAGGCCGTCGAGAGCGTCGCGCGCGGTCACGCATCGCCGCGTCAGTTC
TACGTCGACAAGCTGACGGAAGGTGTCGCGACGATCGCGGCGGCGTTCTATCCGAAGCCCGTCATCGTGCGTCTGTCCGA
CTTCAAGTCGAACGAGTACAAGAAGCTGATCGGCGGTTCGCGTTACGAGCCGGACGAGGAAAACCCGATGCTGGGCTTCC
GCGGCGCGTCGCGTTACATCGCTGAAGACTTCGCGCAGGCGTTCGAAATGGAGTGCCGTGCACTGAAGCGCGTGCGCGAC
GAGATGGGCCTGACCAACGTCGAGATCATGGTGCCGTTCGTGCGTACCGTGAAGCAGGCGGAGCGTGTCGTCGGTCTGCT
CGAGAAGTTCGGTCTGAAGCGCGGCGAAAATGGCCTGCGCCTCGTGATGATGTGCGAAGTCCCGACCAACGCGATCCTCG
CCGAAGACTTCCTGCAGTTCTTCGACGGTTTCTCGATCGGCTCGAACGACCTCACGCAGCTCACGCTCGGCCTCGACCGC
GATTCGGGTATGGAACTGCTGGCTGTCGACTTCGACGAACGCGACCCGGCGGTCAAGTTCCTGCTGAAGCGCGCGATCGA
CACCTGCCGCAAGATGGGCAAGTACGTCGGTATCTGCGGCCAGGGCCCGTCCGATCACCCGGACTTCGCGCAATGGCTGA
CGGACGAAGGCATCGTGTCGATCTCGCTGAACCCCGACACGATCATCGATACGTGGCAGGCGCTCGCCGCCAACCGGAAG
TAA

Upstream 100 bases:

>100_bases
TCTCCAACAGGTTGCGCAAGACGCGTCGCGCCTTTTTGCAAGCGCCCGCGTCCAAGCCCACTTGCGCAATCGAGCATTTT
TTTCACACTTAGGGGCTTGT

Downstream 100 bases:

>100_bases
CGGTCGGTAACTTGCCATCGACGAAGGAGCGGCGCTGCTGCTCCTTCAGTGAAGGCAAATTGCAAGGTTCATGCTATAAA
CACCCCGGTAGATACCGGGG

Product: phosphoenolpyruvate synthase

Products: NA

Alternate protein names: PEP synthase; Pyruvate, water dikinase [H]

Number of amino acids: Translated: 800; Mature: 799

Protein sequence:

>800_residues
MTNAANVAKDQAYVIPFEQLRMTDVEIVGGKNASLGEMISQLSEAGVRVPTGFATTALAFRDFLTHNDLTDRIAKRLESL
DIDDVKALAEAGAEIRKWIVDAPMQARLEQEIREQFEILKNSSPGELSFAVRSSATAEDLPDASFAGQQESYLNVVGIED
VLDRMKHVFASLYNDRAISYRVHKGFTHAEVALSAGVQRMVRSDVGAAGVMFTIDTESGFKDAVFITSSYGLGETVVQGA
VNPDEFYVFKTTLAQDKYPIIRRSIGSKLIKMEFTQPGEPGRVKTVDVPHEQRNRYSITDEDVIELAKYAVIIEKHYQRP
MDIEWGKDGRDGKIFILQARPETVKSQATGKAEQRFKLKGQSQVLATGRAIGQKIGAGPVRVIQDPSEMERVQPGDVLVA
DMTDPNWEPVMKRAAAIVTNRGGRTCHAAIIARELGVPAVVGCGDATDILKDGALVTVSCAEGDEGKIYDGLLETEVTEV
QRGELPEIPVKIMMNVGNPQLAFDFSQLPNGGVGLARLEFIINNNIGVHPKAILEYPNIDQDLKKAVESVARGHASPRQF
YVDKLTEGVATIAAAFYPKPVIVRLSDFKSNEYKKLIGGSRYEPDEENPMLGFRGASRYIAEDFAQAFEMECRALKRVRD
EMGLTNVEIMVPFVRTVKQAERVVGLLEKFGLKRGENGLRLVMMCEVPTNAILAEDFLQFFDGFSIGSNDLTQLTLGLDR
DSGMELLAVDFDERDPAVKFLLKRAIDTCRKMGKYVGICGQGPSDHPDFAQWLTDEGIVSISLNPDTIIDTWQALAANRK

Sequences:

>Translated_800_residues
MTNAANVAKDQAYVIPFEQLRMTDVEIVGGKNASLGEMISQLSEAGVRVPTGFATTALAFRDFLTHNDLTDRIAKRLESL
DIDDVKALAEAGAEIRKWIVDAPMQARLEQEIREQFEILKNSSPGELSFAVRSSATAEDLPDASFAGQQESYLNVVGIED
VLDRMKHVFASLYNDRAISYRVHKGFTHAEVALSAGVQRMVRSDVGAAGVMFTIDTESGFKDAVFITSSYGLGETVVQGA
VNPDEFYVFKTTLAQDKYPIIRRSIGSKLIKMEFTQPGEPGRVKTVDVPHEQRNRYSITDEDVIELAKYAVIIEKHYQRP
MDIEWGKDGRDGKIFILQARPETVKSQATGKAEQRFKLKGQSQVLATGRAIGQKIGAGPVRVIQDPSEMERVQPGDVLVA
DMTDPNWEPVMKRAAAIVTNRGGRTCHAAIIARELGVPAVVGCGDATDILKDGALVTVSCAEGDEGKIYDGLLETEVTEV
QRGELPEIPVKIMMNVGNPQLAFDFSQLPNGGVGLARLEFIINNNIGVHPKAILEYPNIDQDLKKAVESVARGHASPRQF
YVDKLTEGVATIAAAFYPKPVIVRLSDFKSNEYKKLIGGSRYEPDEENPMLGFRGASRYIAEDFAQAFEMECRALKRVRD
EMGLTNVEIMVPFVRTVKQAERVVGLLEKFGLKRGENGLRLVMMCEVPTNAILAEDFLQFFDGFSIGSNDLTQLTLGLDR
DSGMELLAVDFDERDPAVKFLLKRAIDTCRKMGKYVGICGQGPSDHPDFAQWLTDEGIVSISLNPDTIIDTWQALAANRK
>Mature_799_residues
TNAANVAKDQAYVIPFEQLRMTDVEIVGGKNASLGEMISQLSEAGVRVPTGFATTALAFRDFLTHNDLTDRIAKRLESLD
IDDVKALAEAGAEIRKWIVDAPMQARLEQEIREQFEILKNSSPGELSFAVRSSATAEDLPDASFAGQQESYLNVVGIEDV
LDRMKHVFASLYNDRAISYRVHKGFTHAEVALSAGVQRMVRSDVGAAGVMFTIDTESGFKDAVFITSSYGLGETVVQGAV
NPDEFYVFKTTLAQDKYPIIRRSIGSKLIKMEFTQPGEPGRVKTVDVPHEQRNRYSITDEDVIELAKYAVIIEKHYQRPM
DIEWGKDGRDGKIFILQARPETVKSQATGKAEQRFKLKGQSQVLATGRAIGQKIGAGPVRVIQDPSEMERVQPGDVLVAD
MTDPNWEPVMKRAAAIVTNRGGRTCHAAIIARELGVPAVVGCGDATDILKDGALVTVSCAEGDEGKIYDGLLETEVTEVQ
RGELPEIPVKIMMNVGNPQLAFDFSQLPNGGVGLARLEFIINNNIGVHPKAILEYPNIDQDLKKAVESVARGHASPRQFY
VDKLTEGVATIAAAFYPKPVIVRLSDFKSNEYKKLIGGSRYEPDEENPMLGFRGASRYIAEDFAQAFEMECRALKRVRDE
MGLTNVEIMVPFVRTVKQAERVVGLLEKFGLKRGENGLRLVMMCEVPTNAILAEDFLQFFDGFSIGSNDLTQLTLGLDRD
SGMELLAVDFDERDPAVKFLLKRAIDTCRKMGKYVGICGQGPSDHPDFAQWLTDEGIVSISLNPDTIIDTWQALAANRK

Specific function: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787994, Length=788, Percent_Identity=64.7208121827411, Blast_Score=1047, Evalue=0.0,
Organism=Escherichia coli, GI1788756, Length=399, Percent_Identity=26.3157894736842, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1788726, Length=192, Percent_Identity=32.2916666666667, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI48994992, Length=411, Percent_Identity=25.3041362530414, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17564524, Length=237, Percent_Identity=31.6455696202532, Blast_Score=100, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR006319
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.2 [H]

Molecular weight: Translated: 88201; Mature: 88069

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNAANVAKDQAYVIPFEQLRMTDVEIVGGKNASLGEMISQLSEAGVRVPTGFATTALAF
CCCCCCCCCCCEEEEEHHHHCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
RDFLTHNDLTDRIAKRLESLDIDDVKALAEAGAEIRKWIVDAPMQARLEQEIREQFEILK
HHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
NSSPGELSFAVRSSATAEDLPDASFAGQQESYLNVVGIEDVLDRMKHVFASLYNDRAISY
CCCCCCEEEEEECCCCHHCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCEEEE
RVHKGFTHAEVALSAGVQRMVRSDVGAAGVMFTIDTESGFKDAVFITSSYGLGETVVQGA
EECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHCC
VNPDEFYVFKTTLAQDKYPIIRRSIGSKLIKMEFTQPGEPGRVKTVDVPHEQRNRYSITD
CCCCCEEEEEEECCCCCCHHHHHHHCCCEEEEECCCCCCCCCEEEEECCHHHCCCCCCCH
EDVIELAKYAVIIEKHYQRPMDIEWGKDGRDGKIFILQARPETVKSQATGKAEQRFKLKG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHCCCCHHHHEEECC
QSQVLATGRAIGQKIGAGPVRVIQDPSEMERVQPGDVLVADMTDPNWEPVMKRAAAIVTN
CCHHHHHHHHHHHHCCCCCEEEECCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCC
RGGRTCHAAIIARELGVPAVVGCGDATDILKDGALVTVSCAEGDEGKIYDGLLETEVTEV
CCCCCHHHHHHHHHCCCCEEEECCCHHHHHCCCCEEEEEECCCCCCCEEHHHHHHHHHHH
QRGELPEIPVKIMMNVGNPQLAFDFSQLPNGGVGLARLEFIINNNIGVHPKAILEYPNID
HCCCCCCCCEEEEEECCCCCEEEEHHHCCCCCCCCEEEEEEECCCCCCCCHHHCCCCCCC
QDLKKAVESVARGHASPRQFYVDKLTEGVATIAAAFYPKPVIVRLSDFKSNEYKKLIGGS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCC
RYEPDEENPMLGFRGASRYIAEDFAQAFEMECRALKRVRDEMGLTNVEIMVPFVRTVKQA
CCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
ERVVGLLEKFGLKRGENGLRLVMMCEVPTNAILAEDFLQFFDGFSIGSNDLTQLTLGLDR
HHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
DSGMELLAVDFDERDPAVKFLLKRAIDTCRKMGKYVGICGQGPSDHPDFAQWLTDEGIVS
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHCCCCEEE
ISLNPDTIIDTWQALAANRK
EECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TNAANVAKDQAYVIPFEQLRMTDVEIVGGKNASLGEMISQLSEAGVRVPTGFATTALAF
CCCCCCCCCCEEEEEHHHHCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
RDFLTHNDLTDRIAKRLESLDIDDVKALAEAGAEIRKWIVDAPMQARLEQEIREQFEILK
HHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
NSSPGELSFAVRSSATAEDLPDASFAGQQESYLNVVGIEDVLDRMKHVFASLYNDRAISY
CCCCCCEEEEEECCCCHHCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCEEEE
RVHKGFTHAEVALSAGVQRMVRSDVGAAGVMFTIDTESGFKDAVFITSSYGLGETVVQGA
EECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHCC
VNPDEFYVFKTTLAQDKYPIIRRSIGSKLIKMEFTQPGEPGRVKTVDVPHEQRNRYSITD
CCCCCEEEEEEECCCCCCHHHHHHHCCCEEEEECCCCCCCCCEEEEECCHHHCCCCCCCH
EDVIELAKYAVIIEKHYQRPMDIEWGKDGRDGKIFILQARPETVKSQATGKAEQRFKLKG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHCCCCHHHHEEECC
QSQVLATGRAIGQKIGAGPVRVIQDPSEMERVQPGDVLVADMTDPNWEPVMKRAAAIVTN
CCHHHHHHHHHHHHCCCCCEEEECCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCC
RGGRTCHAAIIARELGVPAVVGCGDATDILKDGALVTVSCAEGDEGKIYDGLLETEVTEV
CCCCCHHHHHHHHHCCCCEEEECCCHHHHHCCCCEEEEEECCCCCCCEEHHHHHHHHHHH
QRGELPEIPVKIMMNVGNPQLAFDFSQLPNGGVGLARLEFIINNNIGVHPKAILEYPNID
HCCCCCCCCEEEEEECCCCCEEEEHHHCCCCCCCCEEEEEEECCCCCCCCHHHCCCCCCC
QDLKKAVESVARGHASPRQFYVDKLTEGVATIAAAFYPKPVIVRLSDFKSNEYKKLIGGS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCC
RYEPDEENPMLGFRGASRYIAEDFAQAFEMECRALKRVRDEMGLTNVEIMVPFVRTVKQA
CCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
ERVVGLLEKFGLKRGENGLRLVMMCEVPTNAILAEDFLQFFDGFSIGSNDLTQLTLGLDR
HHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
DSGMELLAVDFDERDPAVKFLLKRAIDTCRKMGKYVGICGQGPSDHPDFAQWLTDEGIVS
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHCCCCEEE
ISLNPDTIIDTWQALAANRK
EECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]