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The map label for this gene is pgi

Identifier: 78066687

GI number: 78066687

Start: 2269633

End: 2271303

Strand: Direct

Name: pgi

Synonym: Bcep18194_A5218

Alternate gene names: 78066687

Gene position: 2269633-2271303 (Clockwise)

Preceding gene: 78066686

Following gene: 78066689

Centisome position: 61.44

GC content: 66.25

Gene sequence:

>1671_bases
ATGAGCCGGCGCGGCATTCCTCCCGATTCACGCTTCACTCGAACCGCCATGACGCTGAATTCGCTCCCCGCCTGGACTGC
CCTTCAATCCCACTTCGAGCAAATCCGCCACGCTCGCCTGCGCGACTGGTTCGCGCCGGAAAACGACCACACGCCGACGC
GTGCCGAACGCTTCACGATTCCGGGCGGCGGTATCGCGGCCGATTTCTCGAAGAACCGCATCAACGACGACACGCTGCGC
CTGCTCGTACAGCTCGCGCGCGACGCGGGCGTCGAAGCCCGCCGCGACGCGATGTTCGCGGGCGAGATCGTCAACCCGAC
CGAAGGCCGGGCCGCGCTGCACACCGCACTGCGCGCGACCGATCCGCAAGCACCGTTCCACGCACAGATCAGCGCCGAGC
GCGCGAAGATGGCGACCTTCGCGCGCGCCGTGCGCAGCGGCACGTGGACGGGCTACACCGGCAAGCGCATCCGCCACGTG
ATCAATATCGGCATCGGCGGTTCCGACCTCGGGCCGAAGATGGTCGTGCATGCGCTGCACCACGTCGCGACGCCCGAAAT
CACCACGCACTTCGTGTCGAACGTCGACGGCGCCGATCTCGCGCGCGTGCTCGAACAGGTCGATCCCGAGGAAACGCTCG
CGATCATCGTGTCGAAGACCTTCACGACGCTCGAGACGATGACGAACGCACGCTCGCTGCGCGACTGGTTCGTCGCGCGC
GGCTGCCCCGAGGACGCGCTCGCGAAGCACTTCGTCGGCGTATCGGCGAATCCGGCCGAAGTCGTGAAGTTCGGCATCGC
CGCGGACAACGTGTTCGAAATGTGGGACTGGGTTGGCGGCCGCTATTCGCTGTGGTCGGCTGTCGGCCTGTCGATCATGA
TCGCGATCGGCCCCGAGCAGTTCGACGAGCTGCTGGCCGGCGCGAACGACATGGACCGTCATTTCCGTGAAGCGCCGCTC
GAGCGCAACCTGCCCGTGCTGCTCGGCCTGATCGGCATCTGGTACCGGAATTTCTTCGGTTCGCAAAGCTATCTCGTCGC
GCCGTATTCGGAAGCGCTGCACTACCTGCCGTCGTACCTGCAGCAGCTCGAAATGGAGAGCAACGGCAAATCCGCGCGCC
TGGACGGCACCTTCGTCGACTACCCGACGTCGGCCGTCACGTGGGGCGAACCGGGCACCAACGGCCAGCATGCGTTCTTC
CAGATGCTGCACCAGGGGCCGACGATCGTGCCGATCGACTTCATCGCGGTGCTGACGCCCGAGCATCCGCTCGCGAGCCA
TCATCCGAAGCTGCTGGCGAACTGCTTTGCGCAGAGCGAGGCACTGATGCTCGGCCGCACGCTCGACGAAGCGCGCAAGG
TCGCAGGTCCGGGCAAGGAAGCGCTCGCGCCGCACCTGACGTTCCCGGGCAACCGCCCGACGACGACGCTGCTCGTCGAT
GCGCTGACGCCGCGCACGCTCGGCGCGCTGATCGCGCTGTACGAACACAAGGTGCTCGTGCAGGCAACGGTGTGGGACAT
CAATCCGTTCGACCAATGGGGCGTCGAGCTCGGCAAGATTCTCGGCAAGGTGGTGGAAGCCGACCTGTCGGCCGAGTCGA
TCGATCCGGCGAAGCACGACTCGTCGACCACTGCGCTGATCGAGCGCGCCCGCGCAGCGTTGAAGCGCTGA

Upstream 100 bases:

>100_bases
TCGCCTTTTTTATGCGTCGCCGCGCGCCGACACGTAACGCCGCTATACTGACTGCCCCGCCGCACGGCGGGCCCTCTCGT
CCGCCGGCCTTCCGATCCCG

Downstream 100 bases:

>100_bases
CGCAACGGCGACATGCCGATGCCGGCCGCGCAGCCCTGCCTGCGCGGCCGGCCGCTAAATTCAGGTGCCGCGTTGCTCCG
CATGCGGCTCGACGATGCGT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MSRRGIPPDSRFTRTAMTLNSLPAWTALQSHFEQIRHARLRDWFAPENDHTPTRAERFTIPGGGIAADFSKNRINDDTLR
LLVQLARDAGVEARRDAMFAGEIVNPTEGRAALHTALRATDPQAPFHAQISAERAKMATFARAVRSGTWTGYTGKRIRHV
INIGIGGSDLGPKMVVHALHHVATPEITTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVAR
GCPEDALAKHFVGVSANPAEVVKFGIAADNVFEMWDWVGGRYSLWSAVGLSIMIAIGPEQFDELLAGANDMDRHFREAPL
ERNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYLQQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFF
QMLHQGPTIVPIDFIAVLTPEHPLASHHPKLLANCFAQSEALMLGRTLDEARKVAGPGKEALAPHLTFPGNRPTTTLLVD
ALTPRTLGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEADLSAESIDPAKHDSSTTALIERARAALKR

Sequences:

>Translated_556_residues
MSRRGIPPDSRFTRTAMTLNSLPAWTALQSHFEQIRHARLRDWFAPENDHTPTRAERFTIPGGGIAADFSKNRINDDTLR
LLVQLARDAGVEARRDAMFAGEIVNPTEGRAALHTALRATDPQAPFHAQISAERAKMATFARAVRSGTWTGYTGKRIRHV
INIGIGGSDLGPKMVVHALHHVATPEITTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVAR
GCPEDALAKHFVGVSANPAEVVKFGIAADNVFEMWDWVGGRYSLWSAVGLSIMIAIGPEQFDELLAGANDMDRHFREAPL
ERNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYLQQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFF
QMLHQGPTIVPIDFIAVLTPEHPLASHHPKLLANCFAQSEALMLGRTLDEARKVAGPGKEALAPHLTFPGNRPTTTLLVD
ALTPRTLGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEADLSAESIDPAKHDSSTTALIERARAALKR
>Mature_555_residues
SRRGIPPDSRFTRTAMTLNSLPAWTALQSHFEQIRHARLRDWFAPENDHTPTRAERFTIPGGGIAADFSKNRINDDTLRL
LVQLARDAGVEARRDAMFAGEIVNPTEGRAALHTALRATDPQAPFHAQISAERAKMATFARAVRSGTWTGYTGKRIRHVI
NIGIGGSDLGPKMVVHALHHVATPEITTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVARG
CPEDALAKHFVGVSANPAEVVKFGIAADNVFEMWDWVGGRYSLWSAVGLSIMIAIGPEQFDELLAGANDMDRHFREAPLE
RNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYLQQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFFQ
MLHQGPTIVPIDFIAVLTPEHPLASHHPKLLANCFAQSEALMLGRTLDEARKVAGPGKEALAPHLTFPGNRPTTTLLVDA
LTPRTLGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEADLSAESIDPAKHDSSTTALIERARAALKR

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=541, Percent_Identity=48.7985212569316, Blast_Score=514, Evalue=1e-146,
Organism=Homo sapiens, GI296080693, Length=557, Percent_Identity=44.7037701974865, Blast_Score=458, Evalue=1e-129,
Organism=Escherichia coli, GI1790457, Length=542, Percent_Identity=48.5239852398524, Blast_Score=516, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI71996708, Length=556, Percent_Identity=47.6618705035971, Blast_Score=504, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI71996703, Length=552, Percent_Identity=47.6449275362319, Blast_Score=500, Evalue=1e-142,
Organism=Saccharomyces cerevisiae, GI6319673, Length=544, Percent_Identity=47.7941176470588, Blast_Score=507, Evalue=1e-144,
Organism=Drosophila melanogaster, GI24651916, Length=553, Percent_Identity=48.6437613019892, Blast_Score=516, Evalue=1e-146,
Organism=Drosophila melanogaster, GI24651914, Length=553, Percent_Identity=48.6437613019892, Blast_Score=516, Evalue=1e-146,
Organism=Drosophila melanogaster, GI17737445, Length=553, Percent_Identity=48.6437613019892, Blast_Score=516, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 61143; Mature: 61012

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRGIPPDSRFTRTAMTLNSLPAWTALQSHFEQIRHARLRDWFAPENDHTPTRAERFTI
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEC
PGGGIAADFSKNRINDDTLRLLVQLARDAGVEARRDAMFAGEIVNPTEGRAALHTALRAT
CCCCEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
DPQAPFHAQISAERAKMATFARAVRSGTWTGYTGKRIRHVINIGIGGSDLGPKMVVHALH
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEECCCCCCCCHHHHHHHHH
HVATPEITTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVAR
HHCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHC
GCPEDALAKHFVGVSANPAEVVKFGIAADNVFEMWDWVGGRYSLWSAVGLSIMIAIGPEQ
CCCHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCEEEEEECHHH
FDELLAGANDMDRHFREAPLERNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYL
HHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHH
QQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIAVLTP
HHHHHCCCCCCEEECCEEEECCCCEEECCCCCCCCHHHHHHHHHCCCCEEEEEEEEEECC
EHPLASHHPKLLANCFAQSEALMLGRTLDEARKVAGPGKEALAPHLTFPGNRPTTTLLVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCEEEEE
ALTPRTLGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEADLSAESIDPAKHD
CCCHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SSTTALIERARAALKR
CHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRRGIPPDSRFTRTAMTLNSLPAWTALQSHFEQIRHARLRDWFAPENDHTPTRAERFTI
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEC
PGGGIAADFSKNRINDDTLRLLVQLARDAGVEARRDAMFAGEIVNPTEGRAALHTALRAT
CCCCEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
DPQAPFHAQISAERAKMATFARAVRSGTWTGYTGKRIRHVINIGIGGSDLGPKMVVHALH
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEECCCCCCCCHHHHHHHHH
HVATPEITTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVAR
HHCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHC
GCPEDALAKHFVGVSANPAEVVKFGIAADNVFEMWDWVGGRYSLWSAVGLSIMIAIGPEQ
CCCHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCEEEEEECHHH
FDELLAGANDMDRHFREAPLERNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYL
HHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHH
QQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIAVLTP
HHHHHCCCCCCEEECCEEEECCCCEEECCCCCCCCHHHHHHHHHCCCCEEEEEEEEEECC
EHPLASHHPKLLANCFAQSEALMLGRTLDEARKVAGPGKEALAPHLTFPGNRPTTTLLVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCEEEEE
ALTPRTLGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEADLSAESIDPAKHD
CCCHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SSTTALIERARAALKR
CHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA