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The map label for this gene is blh [H]

Identifier: 78066513

GI number: 78066513

Start: 2081302

End: 2082969

Strand: Direct

Name: blh [H]

Synonym: Bcep18194_A5044

Alternate gene names: 78066513

Gene position: 2081302-2082969 (Clockwise)

Preceding gene: 78066512

Following gene: 78066514

Centisome position: 56.34

GC content: 71.16

Gene sequence:

>1668_bases
ATGACCATCCGCAAGCTGACCGACGCGCTGTCGGTCTCGCCGCAGATCGCGGCGGCCGACCTGCCTGCGCTTCACGCGGC
CGGCATCCGCGCGATCATCTGCAACCGCCCCGACGGCGAAGGCCCCGACCAGCCGACCGTCACCGAGATCCGAGCGGCCG
CCGCACCGCTCGGCATCGACGTGCACTACCTGCCGGTCGATACGGGCAAGGTGACCGACGACCAGGCCGCGCAGTTCGGC
GCGCTCGTCGCGTCGCTCGACGGCCCGGTGCTCGCGTACTGCCGCAGCGGCACGCGTTCGGCCACGCTGTGGGCGCTGTC
GCAAGCCGGCCTGCGCCCGCTGAACGACATCGTCGCGACGGCCGCTGCGGCCGGCTACGACCTGCGCGCGCTCGCATCGC
GTGTCGTGCAAGGCGGCAAGCAGGCAACACCGGCCGTCGACGCGCGGCACGACATCGTGATCGTCGGCGCGGGCGCGGCC
GGCATCGCGGTCGCGTCGAGCCTGCTCGCGCGCGATGCGTCGCTCGACATCGCGGTGATCGATCCGGCCGACGTTCACTA
TTACCAGCCGGGCTGGACGATGGTCGGCGCGGGCGTGTTCCGGCCCGAGACCACCGCGCGCCGGATGACCGACGTGCTGC
CGCGCGGCGTGCACCGGATCCAGGCCGCCGTCGCGGGCTTCGAGCCCGACGCGCACACGGTCGTGCTCGACGGCTGCCGC
CGCATCGGGTATCGCAAGCTCGTCGTGTGCCCGGGGCTCAAGCTCGACTGGCACGGGATCGAAGGCCTCGCCGACACGCT
CGGCCGCAACGGCGTCACGTCCAACTACCGCTACGATCTCGCGCCGTACACGTGGGAGCTGGTTCGCACGTTCCGCGGCG
GCAACGCACTCTTCACGCAGCCGCCGATGCCGATCAAGTGCGCGGGCGCACCGCAGAAGGCGATGTACCTGTCGTGCGAC
CACTGGCGGCGCGAAGGCCGCCTCGAAGCCGCGAATGTCGAGTTCCTGAATGCGGGCGCCGCGCTGTTCGGCGTCGCCGA
CTACGTGCCCGCGCTGATGGAGTACGTAAAAAGCTACGACATCGCGCTGTCGTTCGGTCACAACCTCGTGTCGATCGACG
GGCCCGCGCGCCGCGCGACATTCGCGCGCGCGCTGCCGGACGGCGGCAAGGAAACCGTCGTGCGTTCGTTCGACATGATC
CACGTCGTGCCGCCGCAGAAGGCGCCCGACTTCGTGCGATCGAGCCCGCTCGCCGACGCGGCCGGCTGGATCGACGTCGA
TCCGGCGACGCTGCGGCACAAGCAATTCCCGGACGTCTACGCGCTCGGCGACGCCACCAACACGACCAATGCGAAAACGG
CCGCGGCCGCCCGCAAGCAGGCGCCGGTGGTCGCGCACAACCTGCTCGCGTCGCTCGGCCGCGCGCACGGCGACGCCGCG
TACGACGGCTACGGCTCGTGCCCGCTCACGGTCGAGCGCGGCAAGATCGTGCTCGCCGAGTTCCTGTACGGCGGCAAGGT
CGCGCCGACCTTCCCCGCGTGGCTGATCGACGGCAAGCGCCCGTCGCGGCTTGCGTGGCTGCTCAAGGAACGCGTGCTGC
CGCCGCTCTACTGGAAGGCGATGCTCAAGGGCCGCGAATGGCTCGCGAAGCCCGCGATCGCACGTTGA

Upstream 100 bases:

>100_bases
GGCCACCTGCCCGAGCCCGAAAACAACGGCGTGCGCTACCTGAAGATCCCGCTCGACGCGATCTGAGCGACACGCCCCGC
CCCCTCCGGAGAACCCCGAC

Downstream 100 bases:

>100_bases
CCGGAGCCCGCTGACGTCATGCTGATTTCCCTCGTCCTAGGCGGTTTCGTCGGTGCCGTGCTCGGCCTGACCGGCGCCGG
CGGCGGCATCCTCGCGGTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MTIRKLTDALSVSPQIAAADLPALHAAGIRAIICNRPDGEGPDQPTVTEIRAAAAPLGIDVHYLPVDTGKVTDDQAAQFG
ALVASLDGPVLAYCRSGTRSATLWALSQAGLRPLNDIVATAAAAGYDLRALASRVVQGGKQATPAVDARHDIVIVGAGAA
GIAVASSLLARDASLDIAVIDPADVHYYQPGWTMVGAGVFRPETTARRMTDVLPRGVHRIQAAVAGFEPDAHTVVLDGCR
RIGYRKLVVCPGLKLDWHGIEGLADTLGRNGVTSNYRYDLAPYTWELVRTFRGGNALFTQPPMPIKCAGAPQKAMYLSCD
HWRREGRLEAANVEFLNAGAALFGVADYVPALMEYVKSYDIALSFGHNLVSIDGPARRATFARALPDGGKETVVRSFDMI
HVVPPQKAPDFVRSSPLADAAGWIDVDPATLRHKQFPDVYALGDATNTTNAKTAAAARKQAPVVAHNLLASLGRAHGDAA
YDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERVLPPLYWKAMLKGREWLAKPAIAR

Sequences:

>Translated_555_residues
MTIRKLTDALSVSPQIAAADLPALHAAGIRAIICNRPDGEGPDQPTVTEIRAAAAPLGIDVHYLPVDTGKVTDDQAAQFG
ALVASLDGPVLAYCRSGTRSATLWALSQAGLRPLNDIVATAAAAGYDLRALASRVVQGGKQATPAVDARHDIVIVGAGAA
GIAVASSLLARDASLDIAVIDPADVHYYQPGWTMVGAGVFRPETTARRMTDVLPRGVHRIQAAVAGFEPDAHTVVLDGCR
RIGYRKLVVCPGLKLDWHGIEGLADTLGRNGVTSNYRYDLAPYTWELVRTFRGGNALFTQPPMPIKCAGAPQKAMYLSCD
HWRREGRLEAANVEFLNAGAALFGVADYVPALMEYVKSYDIALSFGHNLVSIDGPARRATFARALPDGGKETVVRSFDMI
HVVPPQKAPDFVRSSPLADAAGWIDVDPATLRHKQFPDVYALGDATNTTNAKTAAAARKQAPVVAHNLLASLGRAHGDAA
YDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERVLPPLYWKAMLKGREWLAKPAIAR
>Mature_554_residues
TIRKLTDALSVSPQIAAADLPALHAAGIRAIICNRPDGEGPDQPTVTEIRAAAAPLGIDVHYLPVDTGKVTDDQAAQFGA
LVASLDGPVLAYCRSGTRSATLWALSQAGLRPLNDIVATAAAAGYDLRALASRVVQGGKQATPAVDARHDIVIVGAGAAG
IAVASSLLARDASLDIAVIDPADVHYYQPGWTMVGAGVFRPETTARRMTDVLPRGVHRIQAAVAGFEPDAHTVVLDGCRR
IGYRKLVVCPGLKLDWHGIEGLADTLGRNGVTSNYRYDLAPYTWELVRTFRGGNALFTQPPMPIKCAGAPQKAMYLSCDH
WRREGRLEAANVEFLNAGAALFGVADYVPALMEYVKSYDIALSFGHNLVSIDGPARRATFARALPDGGKETVVRSFDMIH
VVPPQKAPDFVRSSPLADAAGWIDVDPATLRHKQFPDVYALGDATNTTNAKTAAAARKQAPVVAHNLLASLGRAHGDAAY
DGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERVLPPLYWKAMLKGREWLAKPAIAR

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI10864011, Length=414, Percent_Identity=35.9903381642512, Blast_Score=299, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI115534373, Length=346, Percent_Identity=36.7052023121387, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17539680, Length=421, Percent_Identity=31.5914489311164, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI24657386, Length=398, Percent_Identity=36.9346733668342, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24657391, Length=398, Percent_Identity=36.9346733668342, Blast_Score=254, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 59293; Mature: 59161

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRKLTDALSVSPQIAAADLPALHAAGIRAIICNRPDGEGPDQPTVTEIRAAAAPLGID
CCHHHHHHHHCCCCCHHHCCCCHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCE
VHYLPVDTGKVTDDQAAQFGALVASLDGPVLAYCRSGTRSATLWALSQAGLRPLNDIVAT
EEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHHCCCCHHHHHHHH
AAAAGYDLRALASRVVQGGKQATPAVDARHDIVIVGAGAAGIAVASSLLARDASLDIAVI
HHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEE
DPADVHYYQPGWTMVGAGVFRPETTARRMTDVLPRGVHRIQAAVAGFEPDAHTVVLDGCR
CCCCCEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHH
RIGYRKLVVCPGLKLDWHGIEGLADTLGRNGVTSNYRYDLAPYTWELVRTFRGGNALFTQ
HCCCEEEEECCCCEEECCCCHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHCCCCEEEEC
PPMPIKCAGAPQKAMYLSCDHWRREGRLEAANVEFLNAGAALFGVADYVPALMEYVKSYD
CCCCEEECCCCCCEEEEECHHHHCCCCEEECCEEEEECCHHHHHHHHHHHHHHHHHHHCC
IALSFGHNLVSIDGPARRATFARALPDGGKETVVRSFDMIHVVPPQKAPDFVRSSPLADA
EEEEECCCEEEECCCHHHHHHHHHCCCCCHHHHHHHCCEEEEECCCCCCHHHHCCCCCCC
AGWIDVDPATLRHKQFPDVYALGDATNTTNAKTAAAARKQAPVVAHNLLASLGRAHGDAA
CCEEECCHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
YDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERVLPPLYWKA
CCCCCCCCEEEECCCEEEEEHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCHHHHHH
MLKGREWLAKPAIAR
HHHCHHHHCCCCCCC
>Mature Secondary Structure 
TIRKLTDALSVSPQIAAADLPALHAAGIRAIICNRPDGEGPDQPTVTEIRAAAAPLGID
CHHHHHHHHCCCCCHHHCCCCHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCE
VHYLPVDTGKVTDDQAAQFGALVASLDGPVLAYCRSGTRSATLWALSQAGLRPLNDIVAT
EEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHHCCCCHHHHHHHH
AAAAGYDLRALASRVVQGGKQATPAVDARHDIVIVGAGAAGIAVASSLLARDASLDIAVI
HHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEE
DPADVHYYQPGWTMVGAGVFRPETTARRMTDVLPRGVHRIQAAVAGFEPDAHTVVLDGCR
CCCCCEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHH
RIGYRKLVVCPGLKLDWHGIEGLADTLGRNGVTSNYRYDLAPYTWELVRTFRGGNALFTQ
HCCCEEEEECCCCEEECCCCHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHCCCCEEEEC
PPMPIKCAGAPQKAMYLSCDHWRREGRLEAANVEFLNAGAALFGVADYVPALMEYVKSYD
CCCCEEECCCCCCEEEEECHHHHCCCCEEECCEEEEECCHHHHHHHHHHHHHHHHHHHCC
IALSFGHNLVSIDGPARRATFARALPDGGKETVVRSFDMIHVVPPQKAPDFVRSSPLADA
EEEEECCCEEEECCCHHHHHHHHHCCCCCHHHHHHHCCEEEEECCCCCCHHHHCCCCCCC
AGWIDVDPATLRHKQFPDVYALGDATNTTNAKTAAAARKQAPVVAHNLLASLGRAHGDAA
CCEEECCHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
YDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLIDGKRPSRLAWLLKERVLPPLYWKA
CCCCCCCCEEEECCCEEEEEHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCHHHHHH
MLKGREWLAKPAIAR
HHHCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]