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The map label for this gene is rssA [H]

Identifier: 78066489

GI number: 78066489

Start: 2054758

End: 2056182

Strand: Direct

Name: rssA [H]

Synonym: Bcep18194_A5020

Alternate gene names: 78066489

Gene position: 2054758-2056182 (Clockwise)

Preceding gene: 78066488

Following gene: 78066491

Centisome position: 55.62

GC content: 71.02

Gene sequence:

>1425_bases
ATGGATGGTTTCAAGAAGCGGCTGAACGAATCGATCGGCTTCCGCCTGTCGGTCGCGCTGTCGGCCGCGATCCTGGTCGT
CGCGACGGCCGCGGCCGCGTTCGCGTTTTCATCGGCATTCGACGAAGCGCACGAACTGCAGGACGACGTGCTGCGCGAGG
TCGCGACGCTGCTCGACCGCGAGCACACGCCGTCGCTCCATGCCGACGGCACCGGGCCCGCGCGCGAAAGCGACGAGCTG
TCGCGCGTGATCGTGCAGCCGCTCGGCGGCACACCGCAGCCAGGCAGCGACGGCACGCCGCCGCTCGCGCTGGCGCCGAC
GCTCGCCGACGGGCTGCATACGGTCGATACCGGCGGCAGCACGTATCGCGTGATGGTCCGGACCTTCGCGAACGGCGAGC
GCATCGCGGTCGCGCAGGAAGCCGGCATGCGCGACGATGTCGCCCGCGAAAGCGCGTGGCGCACCGCATTGCCGCTGCTG
ATTCTCGTGCCGATCCTGCTGCTGCTCGTCGCCGATCTCGTGCGCAAGCTGTTCCGCCCGGTGGCCGTGCTGTCCGCCGG
CATCGATGCGCGCGACAAGCACGACCTGCGCCCGGTGCCGGCCGAGCGCGTGCCGGTCGAGGTGCGGCCGTTCGTCGTCG
CGATCAACCGGATGCTGGAGCGCGTCGCGCAGTCGGTTGCCGCGCAGCGCCGCTTCGTCGCCGACGCCGCGCACGAGTTG
CGCTCGCCACTCACCGCGATGTCGCTGCAGGCCGAGCGCCTCGCCGAGGCCGACCTGCCGGACGATGCGCGCGCACGGCT
CACCGCGCTGCGCGGCGGCCTCGACCGCAGCCGCCACCTGATCGGGCAGCTGCTCGCGCTCGCACGGGCGCAAAGCGCGC
CGGCCGCGCCGCCCGGTAACGTGTCGGTCCATGCGGTCTATCGCCGCGTGCTGGAAGACCTGATGCCGCTCGCCGACGCG
AAAGCCATCGACATCGGCATCGAAGACGGCCCGGATACCTCCGTGCCCGTCGACGAGCTCGAACTCGTATCGCTCGTGAT
GAACCTGGTCGACAACGCGATCCGCTACACGCCGCCGGGCGGACGCGTGGACCTGTCGACGCAACGCACGGACACGCACG
CATGCGTGACGATCGCCGATACCGGCCCGGGCATCGCGCCGCACGAACGCGAGCGCGTATTCGATCCGTTCTACCGGGTG
CCGGGCAATGCGCAGATCGGCTCCGGGCTCGGCCTGTCGATCGTGAAGATCGTCGCGGACCGGATCGGCGCCGGCATCAC
GCTCGCGTATGCGGACGAAGCGGAATCGCGCGGGTTGCGCATCTCGGTGCGGATTCCGCTGGTGCAGACGCCTGGCGCGA
CGCAGCCCGACAGCGCGGCCGATACGCCGGCGCAACACGCACCGCGCGACGGAGGCCATGCTTGA

Upstream 100 bases:

>100_bases
GCTGGGGCGAGGAAGTCGAAAGCAATGCGGTCGAATTCCTGATCCATTCGCTGCGCCGCAAGCTCGGCAGCACCGTGATC
AAGAACGTCAGGGGTGCGGG

Downstream 100 bases:

>100_bases
ACGTCAGCCGCCGATTGTCCCGCGATCGATCTTGCGCGACAGGATGATCGACGTCGTCGTGCGTTCGACGCCTTCGAGCG
TGCCGATCTGGTCGAGCAGG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MDGFKKRLNESIGFRLSVALSAAILVVATAAAAFAFSSAFDEAHELQDDVLREVATLLDREHTPSLHADGTGPARESDEL
SRVIVQPLGGTPQPGSDGTPPLALAPTLADGLHTVDTGGSTYRVMVRTFANGERIAVAQEAGMRDDVARESAWRTALPLL
ILVPILLLLVADLVRKLFRPVAVLSAGIDARDKHDLRPVPAERVPVEVRPFVVAINRMLERVAQSVAAQRRFVADAAHEL
RSPLTAMSLQAERLAEADLPDDARARLTALRGGLDRSRHLIGQLLALARAQSAPAAPPGNVSVHAVYRRVLEDLMPLADA
KAIDIGIEDGPDTSVPVDELELVSLVMNLVDNAIRYTPPGGRVDLSTQRTDTHACVTIADTGPGIAPHERERVFDPFYRV
PGNAQIGSGLGLSIVKIVADRIGAGITLAYADEAESRGLRISVRIPLVQTPGATQPDSAADTPAQHAPRDGGHA

Sequences:

>Translated_474_residues
MDGFKKRLNESIGFRLSVALSAAILVVATAAAAFAFSSAFDEAHELQDDVLREVATLLDREHTPSLHADGTGPARESDEL
SRVIVQPLGGTPQPGSDGTPPLALAPTLADGLHTVDTGGSTYRVMVRTFANGERIAVAQEAGMRDDVARESAWRTALPLL
ILVPILLLLVADLVRKLFRPVAVLSAGIDARDKHDLRPVPAERVPVEVRPFVVAINRMLERVAQSVAAQRRFVADAAHEL
RSPLTAMSLQAERLAEADLPDDARARLTALRGGLDRSRHLIGQLLALARAQSAPAAPPGNVSVHAVYRRVLEDLMPLADA
KAIDIGIEDGPDTSVPVDELELVSLVMNLVDNAIRYTPPGGRVDLSTQRTDTHACVTIADTGPGIAPHERERVFDPFYRV
PGNAQIGSGLGLSIVKIVADRIGAGITLAYADEAESRGLRISVRIPLVQTPGATQPDSAADTPAQHAPRDGGHA
>Mature_474_residues
MDGFKKRLNESIGFRLSVALSAAILVVATAAAAFAFSSAFDEAHELQDDVLREVATLLDREHTPSLHADGTGPARESDEL
SRVIVQPLGGTPQPGSDGTPPLALAPTLADGLHTVDTGGSTYRVMVRTFANGERIAVAQEAGMRDDVARESAWRTALPLL
ILVPILLLLVADLVRKLFRPVAVLSAGIDARDKHDLRPVPAERVPVEVRPFVVAINRMLERVAQSVAAQRRFVADAAHEL
RSPLTAMSLQAERLAEADLPDDARARLTALRGGLDRSRHLIGQLLALARAQSAPAAPPGNVSVHAVYRRVLEDLMPLADA
KAIDIGIEDGPDTSVPVDELELVSLVMNLVDNAIRYTPPGGRVDLSTQRTDTHACVTIADTGPGIAPHERERVFDPFYRV
PGNAQIGSGLGLSIVKIVADRIGAGITLAYADEAESRGLRISVRIPLVQTPGATQPDSAADTPAQHAPRDGGHA

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=319, Percent_Identity=33.8557993730408, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790551, Length=307, Percent_Identity=30.2931596091205, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786783, Length=299, Percent_Identity=29.7658862876254, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788279, Length=303, Percent_Identity=26.7326732673267, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=30.8300395256917, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790861, Length=302, Percent_Identity=31.4569536423841, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790346, Length=277, Percent_Identity=26.3537906137184, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=27.3092369477912, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788393, Length=249, Percent_Identity=26.1044176706827, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787894, Length=260, Percent_Identity=29.2307692307692, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787374, Length=294, Percent_Identity=25.8503401360544, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=311, Percent_Identity=23.4726688102894, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=257, Percent_Identity=26.8482490272374, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=297, Percent_Identity=26.2626262626263, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=26.271186440678, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=24.8908296943231, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788549, Length=195, Percent_Identity=26.6666666666667, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50429; Mature: 50429

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGFKKRLNESIGFRLSVALSAAILVVATAAAAFAFSSAFDEAHELQDDVLREVATLLDR
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EHTPSLHADGTGPARESDELSRVIVQPLGGTPQPGSDGTPPLALAPTLADGLHTVDTGGS
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEECCHHHCCCEEECCCCC
TYRVMVRTFANGERIAVAQEAGMRDDVARESAWRTALPLLILVPILLLLVADLVRKLFRP
EEEEEEEECCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAVLSAGIDARDKHDLRPVPAERVPVEVRPFVVAINRMLERVAQSVAAQRRFVADAAHEL
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSPLTAMSLQAERLAEADLPDDARARLTALRGGLDRSRHLIGQLLALARAQSAPAAPPGN
HCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
VSVHAVYRRVLEDLMPLADAKAIDIGIEDGPDTSVPVDELELVSLVMNLVDNAIRYTPPG
CHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCC
GRVDLSTQRTDTHACVTIADTGPGIAPHERERVFDPFYRVPGNAQIGSGLGLSIVKIVAD
CEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHH
RIGAGITLAYADEAESRGLRISVRIPLVQTPGATQPDSAADTPAQHAPRDGGHA
HHCCCEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure
MDGFKKRLNESIGFRLSVALSAAILVVATAAAAFAFSSAFDEAHELQDDVLREVATLLDR
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EHTPSLHADGTGPARESDELSRVIVQPLGGTPQPGSDGTPPLALAPTLADGLHTVDTGGS
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEECCHHHCCCEEECCCCC
TYRVMVRTFANGERIAVAQEAGMRDDVARESAWRTALPLLILVPILLLLVADLVRKLFRP
EEEEEEEECCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAVLSAGIDARDKHDLRPVPAERVPVEVRPFVVAINRMLERVAQSVAAQRRFVADAAHEL
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSPLTAMSLQAERLAEADLPDDARARLTALRGGLDRSRHLIGQLLALARAQSAPAAPPGN
HCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
VSVHAVYRRVLEDLMPLADAKAIDIGIEDGPDTSVPVDELELVSLVMNLVDNAIRYTPPG
CHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCC
GRVDLSTQRTDTHACVTIADTGPGIAPHERERVFDPFYRVPGNAQIGSGLGLSIVKIVAD
CEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHH
RIGAGITLAYADEAESRGLRISVRIPLVQTPGATQPDSAADTPAQHAPRDGGHA
HHCCCEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA