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The map label for this gene is yafC [H]

Identifier: 78066354

GI number: 78066354

Start: 1899614

End: 1900579

Strand: Direct

Name: yafC [H]

Synonym: Bcep18194_A4884

Alternate gene names: 78066354

Gene position: 1899614-1900579 (Clockwise)

Preceding gene: 78066348

Following gene: 78066356

Centisome position: 51.42

GC content: 68.32

Gene sequence:

>966_bases
ATGCAACGACAATTCGACGATCTGCTGCTCGGCAGCATCGAGCTGTTCTGCCTCGCCGCCGAACTCGGCAGCTTCACGCT
GGCGGCCAACGCGGCGAGCGTCACGCCGGCTGCGGTCAGCCGGTCGGTCGCGCGGCTCGAGGAGCGTCTCGGCGTGCGGC
TGTTCGTGCGCACGACACGCCAGATCCGCCTGACCGATTCCGGCCGCCGCTATTTCGAGCAATGCCGCGACGCGCTGTCG
CAACTCGTCGACGCCGAACGCGAGGCGACCGGCCAGCAGGCCACGCCCGCCGGCTTGCTGCGGATCAGCATGCCGACGCC
GTACGGACACTATCGCGTGCTGCCGCTGCTTCCGGCGTTTCGCGAGCGGTACCCGGACGTGCGCGTCGAAACCCACCTGA
GCAATCGCAACATCGACTTCGCCGAGGAAGGCTACGATCTCGCGATCCGGGGACGCGCGCCGGCCGATTCGAACCTGGTC
GCGCGCACGCTGGAAGATGCCGAACTCGTGATCGTCGCGACGCCCGGCTACCTGAAGCGTGCGGGCACGCCGACCGTCAT
CGACGATCTGCATGCGCACGAATGCATCCAGTTCGAACTGCCGAGCAGCGGGCGGCAGATTCCGTGGCTGTTCAGCGATG
GCTCAGAGGAAATCGACGTCGCGACGACCGGCAGCTACGGTACGTCGGGCGACTACCTTGCCGGCGTGACGCTCGCGCGC
AGCGGTGCGGGCCTGTTCCAGGCCTACCGTTTCATCGTCGAGCAGGATCTGCGGGCCGGCACGCTCGTGGAAGTGCTGCC
CGGCCTCGGCGGCCGGTCGCGGCCGTTCATGCTGCTGTATCCGCATGCGCGCTTTCTGTCGTCGCGCGTGCGCGTGTTCG
TCGACTTCCTCATCGAGCATCTGGCACGCGCGCCAGCCAGGCCCGCGACCGGCACACGCACCAAACGGGCCGGCGCATCG
CGCTAG

Upstream 100 bases:

>100_bases
GTAACGAATCACGCCATGCACGCGCGCTGGTTTCCCGTGCGAGATTCATGCACACTCGGCGTCATCGCGCGCACGCGCCG
GAGACGGCAGGAATCGCCCC

Downstream 100 bases:

>100_bases
ACGCGCCGGCGCGCGGTTTCGACGCCGCGACTCAATGCCCGGCGCTCTGGCCGCCGTCGACATGCAGGATCTCGCCCGTG
ACGAACGGCGCCGAGTCCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MQRQFDDLLLGSIELFCLAAELGSFTLAANAASVTPAAVSRSVARLEERLGVRLFVRTTRQIRLTDSGRRYFEQCRDALS
QLVDAEREATGQQATPAGLLRISMPTPYGHYRVLPLLPAFRERYPDVRVETHLSNRNIDFAEEGYDLAIRGRAPADSNLV
ARTLEDAELVIVATPGYLKRAGTPTVIDDLHAHECIQFELPSSGRQIPWLFSDGSEEIDVATTGSYGTSGDYLAGVTLAR
SGAGLFQAYRFIVEQDLRAGTLVEVLPGLGGRSRPFMLLYPHARFLSSRVRVFVDFLIEHLARAPARPATGTRTKRAGAS
R

Sequences:

>Translated_321_residues
MQRQFDDLLLGSIELFCLAAELGSFTLAANAASVTPAAVSRSVARLEERLGVRLFVRTTRQIRLTDSGRRYFEQCRDALS
QLVDAEREATGQQATPAGLLRISMPTPYGHYRVLPLLPAFRERYPDVRVETHLSNRNIDFAEEGYDLAIRGRAPADSNLV
ARTLEDAELVIVATPGYLKRAGTPTVIDDLHAHECIQFELPSSGRQIPWLFSDGSEEIDVATTGSYGTSGDYLAGVTLAR
SGAGLFQAYRFIVEQDLRAGTLVEVLPGLGGRSRPFMLLYPHARFLSSRVRVFVDFLIEHLARAPARPATGTRTKRAGAS
R
>Mature_321_residues
MQRQFDDLLLGSIELFCLAAELGSFTLAANAASVTPAAVSRSVARLEERLGVRLFVRTTRQIRLTDSGRRYFEQCRDALS
QLVDAEREATGQQATPAGLLRISMPTPYGHYRVLPLLPAFRERYPDVRVETHLSNRNIDFAEEGYDLAIRGRAPADSNLV
ARTLEDAELVIVATPGYLKRAGTPTVIDDLHAHECIQFELPSSGRQIPWLFSDGSEEIDVATTGSYGTSGDYLAGVTLAR
SGAGLFQAYRFIVEQDLRAGTLVEVLPGLGGRSRPFMLLYPHARFLSSRVRVFVDFLIEHLARAPARPATGTRTKRAGAS
R

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=38.5135135135135, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787128, Length=283, Percent_Identity=28.6219081272085, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1789440, Length=289, Percent_Identity=26.9896193771626, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787589, Length=287, Percent_Identity=29.9651567944251, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=27.5510204081633, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87081978, Length=298, Percent_Identity=28.5234899328859, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788706, Length=272, Percent_Identity=29.0441176470588, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1786448, Length=297, Percent_Identity=25.5892255892256, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789173, Length=261, Percent_Identity=28.735632183908, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI157672245, Length=128, Percent_Identity=36.71875, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788481, Length=298, Percent_Identity=27.5167785234899, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI145693105, Length=121, Percent_Identity=31.404958677686, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082132, Length=161, Percent_Identity=29.8136645962733, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35366; Mature: 35366

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRQFDDLLLGSIELFCLAAELGSFTLAANAASVTPAAVSRSVARLEERLGVRLFVRTTR
CCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEECE
QIRLTDSGRRYFEQCRDALSQLVDAEREATGQQATPAGLLRISMPTPYGHYRVLPLLPAF
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCHHH
RERYPDVRVETHLSNRNIDFAEEGYDLAIRGRAPADSNLVARTLEDAELVIVATPGYLKR
HHHCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCHHHEECCCCCEEEEECCCHHHH
AGTPTVIDDLHAHECIQFELPSSGRQIPWLFSDGSEEIDVATTGSYGTSGDYLAGVTLAR
CCCCHHHHHHCCCCEEEEECCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCEEEEECC
SGAGLFQAYRFIVEQDLRAGTLVEVLPGLGGRSRPFMLLYPHARFLSSRVRVFVDFLIEH
CCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
LARAPARPATGTRTKRAGASR
HHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQRQFDDLLLGSIELFCLAAELGSFTLAANAASVTPAAVSRSVARLEERLGVRLFVRTTR
CCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEECE
QIRLTDSGRRYFEQCRDALSQLVDAEREATGQQATPAGLLRISMPTPYGHYRVLPLLPAF
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCHHH
RERYPDVRVETHLSNRNIDFAEEGYDLAIRGRAPADSNLVARTLEDAELVIVATPGYLKR
HHHCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCHHHEECCCCCEEEEECCCHHHH
AGTPTVIDDLHAHECIQFELPSSGRQIPWLFSDGSEEIDVATTGSYGTSGDYLAGVTLAR
CCCCHHHHHHCCCCEEEEECCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCEEEEECC
SGAGLFQAYRFIVEQDLRAGTLVEVLPGLGGRSRPFMLLYPHARFLSSRVRVFVDFLIEH
CCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
LARAPARPATGTRTKRAGASR
HHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]