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The map label for this gene is 78066324

Identifier: 78066324

GI number: 78066324

Start: 1872160

End: 1872543

Strand: Direct

Name: 78066324

Synonym: Bcep18194_A4854

Alternate gene names: NA

Gene position: 1872160-1872543 (Clockwise)

Preceding gene: 78066323

Following gene: 78066325

Centisome position: 50.68

GC content: 63.8

Gene sequence:

>384_bases
ATGGCGCTGATTGACCACCTCGACCATCTCGTGCTGACCTGCGTCGATCCCGACAAGACCAGGCATTTCTACACCGAGGT
GCTGCAGATGCAGCTCGAAACCTTCGGCGCCGGCCGGATCGCGTTCCGCTTCGGCAACCAGAAGATCAACCTGCACGTGC
GCGGCGCGGAGTTCGAACCGAAAGCGCATGTGCCGGCGCCCGGCGCGCTCGACCTGTGCTTCATCGCGTCGGTGCCGCTC
GACGACGTGATTGCGCACCTGAAGCGCGTTGCATGGCCGATCGTCGAAGGGCCCGTCGAACGCACCGGCGCGACGCAGAA
GATCCGGTCGGTCTACGTGCGCGATCCCGACCTGAACCTGATCGAGATCTCCGAGTTGATCTGA

Upstream 100 bases:

>100_bases
GCCGGGCGCCGCTCGGACCTTCATCCGCCGCCGCGCGCGGACGCCGGCGACATGCCCGCGCAGCGCGCGTTCTCATGAAC
CACGAACAGGAGCCAATCTC

Downstream 100 bases:

>100_bases
GCACCCGCGCACCGTCGGCCGTATCGCGCGTTCGCACTCGCGTGTGTGGACCTGGTCACGGTGCGGCCGCATGCCGCGCC
GATCTCCCGCCGAAAACGGA

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MALIDHLDHLVLTCVDPDKTRHFYTEVLQMQLETFGAGRIAFRFGNQKINLHVRGAEFEPKAHVPAPGALDLCFIASVPL
DDVIAHLKRVAWPIVEGPVERTGATQKIRSVYVRDPDLNLIEISELI

Sequences:

>Translated_127_residues
MALIDHLDHLVLTCVDPDKTRHFYTEVLQMQLETFGAGRIAFRFGNQKINLHVRGAEFEPKAHVPAPGALDLCFIASVPL
DDVIAHLKRVAWPIVEGPVERTGATQKIRSVYVRDPDLNLIEISELI
>Mature_126_residues
ALIDHLDHLVLTCVDPDKTRHFYTEVLQMQLETFGAGRIAFRFGNQKINLHVRGAEFEPKAHVPAPGALDLCFIASVPLD
DVIAHLKRVAWPIVEGPVERTGATQKIRSVYVRDPDLNLIEISELI

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=126, Percent_Identity=53.1746031746032, Blast_Score=133, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14251; Mature: 14120

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIDHLDHLVLTCVDPDKTRHFYTEVLQMQLETFGAGRIAFRFGNQKINLHVRGAEFEP
CCHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCCCCC
KAHVPAPGALDLCFIASVPLDDVIAHLKRVAWPIVEGPVERTGATQKIRSVYVRDPDLNL
CCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEECCCCCE
IEISELI
EEHHHCC
>Mature Secondary Structure 
ALIDHLDHLVLTCVDPDKTRHFYTEVLQMQLETFGAGRIAFRFGNQKINLHVRGAEFEP
CHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCCCCC
KAHVPAPGALDLCFIASVPLDDVIAHLKRVAWPIVEGPVERTGATQKIRSVYVRDPDLNL
CCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEECCCCCE
IEISELI
EEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]