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The map label for this gene is tauD [H]

Identifier: 78066311

GI number: 78066311

Start: 1858823

End: 1859671

Strand: Direct

Name: tauD [H]

Synonym: Bcep18194_A4841

Alternate gene names: 78066311

Gene position: 1858823-1859671 (Clockwise)

Preceding gene: 78066310

Following gene: 78066312

Centisome position: 50.32

GC content: 67.26

Gene sequence:

>849_bases
ATGCGAGTCGAACCCCTGACCTGCGCGATCGGCGCGGAACTGCTGGATGTGAGCCTCGCCGACGCCGTGCACGACGACGG
CCTGTTCGCCGAGATCCGTGCGCAATTGCTCCGGCATCGCGTGCTGTTCCTGCGCGATCAGGACATCACGCGCGCCGAGC
ACGTCGCGTTCGCGCGACGCTTCGGCGAGCTCGAGGATCACCCGGTTGCCGGCAGCGATCCCGAACACCCGGGGCTCGTG
CGGATCTACAAGTCGCCCGACCAGCCGAACGACCGCTACGAGAATGCGTGGCACAGCGATGCGAGCTGGCGCGTGGCGCC
GCCGTTCGGCTGTGTGCTGCGCTGCATCGACGGTCCGCCGGTTGGCGGCGACACGATGTGGGCGAACATGGTGCTCGCCT
ACGAGCGCTTGCCGGCGCACGTGAAGCAGCAGATCGACGACTTGCGCGCGCGCCACAGCATCGAGGCGAGCTTCGGCGCC
GCGATGCCGATCGACAAACGCCTCGCGCTGAAGGCGCAGTACCCGGACGCCGAGCATCCGGTCGTGCGCACGCATCCCGA
AACCGGCGAGAAGGTGCTGTACGTGAATGCGTTCGCGACGCATTTCACGAACTTCCACACGCCGGCGCGCGTGCGGGTCG
GGCAGGATGCGAATCCCGGCGCCGGCCAGTTGCTGCAATACCTGATCAGCCAGGCTTATATCCCCGAGTACCAGGTGCGC
TGGCGCTGGAAGAAGAACAGCGTCGCGATCTGGGACAACCGCAGCACCCAGCACTACGCGGTGATGGACTACCCGCCGTG
CGTGCGCAAGATGGAGCGCGCGGGCATCGTCGGCGACGTGCCGTTCTGA

Upstream 100 bases:

>100_bases
AACCAGCGCTACGCGCTGCAGGATGCCGCGCAGGCGCACCGCGATCTCGAATCGCGCAAGACGACCGGTTCGTCGGTGTT
CATCGTCTGAGGAGACGCGC

Downstream 100 bases:

>100_bases
GCACGGCAGGCCCGTAACCGGTCTCTGAAAAACCATGCAACGCGCCGGGCCTCCCGCCCGGCGTGGCGGGATACGCACGC
CCGTACGCCCGAAATACAAC

Product: taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MRVEPLTCAIGAELLDVSLADAVHDDGLFAEIRAQLLRHRVLFLRDQDITRAEHVAFARRFGELEDHPVAGSDPEHPGLV
RIYKSPDQPNDRYENAWHSDASWRVAPPFGCVLRCIDGPPVGGDTMWANMVLAYERLPAHVKQQIDDLRARHSIEASFGA
AMPIDKRLALKAQYPDAEHPVVRTHPETGEKVLYVNAFATHFTNFHTPARVRVGQDANPGAGQLLQYLISQAYIPEYQVR
WRWKKNSVAIWDNRSTQHYAVMDYPPCVRKMERAGIVGDVPF

Sequences:

>Translated_282_residues
MRVEPLTCAIGAELLDVSLADAVHDDGLFAEIRAQLLRHRVLFLRDQDITRAEHVAFARRFGELEDHPVAGSDPEHPGLV
RIYKSPDQPNDRYENAWHSDASWRVAPPFGCVLRCIDGPPVGGDTMWANMVLAYERLPAHVKQQIDDLRARHSIEASFGA
AMPIDKRLALKAQYPDAEHPVVRTHPETGEKVLYVNAFATHFTNFHTPARVRVGQDANPGAGQLLQYLISQAYIPEYQVR
WRWKKNSVAIWDNRSTQHYAVMDYPPCVRKMERAGIVGDVPF
>Mature_282_residues
MRVEPLTCAIGAELLDVSLADAVHDDGLFAEIRAQLLRHRVLFLRDQDITRAEHVAFARRFGELEDHPVAGSDPEHPGLV
RIYKSPDQPNDRYENAWHSDASWRVAPPFGCVLRCIDGPPVGGDTMWANMVLAYERLPAHVKQQIDDLRARHSIEASFGA
AMPIDKRLALKAQYPDAEHPVVRTHPETGEKVLYVNAFATHFTNFHTPARVRVGQDANPGAGQLLQYLISQAYIPEYQVR
WRWKKNSVAIWDNRSTQHYAVMDYPPCVRKMERAGIVGDVPF

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=288, Percent_Identity=37.1527777777778, Blast_Score=179, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6322971, Length=276, Percent_Identity=27.8985507246377, Blast_Score=106, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 31921; Mature: 31921

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVEPLTCAIGAELLDVSLADAVHDDGLFAEIRAQLLRHRVLFLRDQDITRAEHVAFARR
CCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHH
FGELEDHPVAGSDPEHPGLVRIYKSPDQPNDRYENAWHSDASWRVAPPFGCVLRCIDGPP
HCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHCCCCCCCCCCEECCCHHHHEEECCCCC
VGGDTMWANMVLAYERLPAHVKQQIDDLRARHSIEASFGAAMPIDKRLALKAQYPDAEHP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCC
VVRTHPETGEKVLYVNAFATHFTNFHTPARVRVGQDANPGAGQLLQYLISQAYIPEYQVR
EEEECCCCCCEEEEEEHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEE
WRWKKNSVAIWDNRSTQHYAVMDYPPCVRKMERAGIVGDVPF
EEEECCCEEEEECCCCCEEEEECCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRVEPLTCAIGAELLDVSLADAVHDDGLFAEIRAQLLRHRVLFLRDQDITRAEHVAFARR
CCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHH
FGELEDHPVAGSDPEHPGLVRIYKSPDQPNDRYENAWHSDASWRVAPPFGCVLRCIDGPP
HCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHCCCCCCCCCCEECCCHHHHEEECCCCC
VGGDTMWANMVLAYERLPAHVKQQIDDLRARHSIEASFGAAMPIDKRLALKAQYPDAEHP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCC
VVRTHPETGEKVLYVNAFATHFTNFHTPARVRVGQDANPGAGQLLQYLISQAYIPEYQVR
EEEECCCCCCEEEEEEHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEE
WRWKKNSVAIWDNRSTQHYAVMDYPPCVRKMERAGIVGDVPF
EEEECCCEEEEECCCCCEEEEECCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]