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The map label for this gene is cynX [H]

Identifier: 78066302

GI number: 78066302

Start: 1848139

End: 1849317

Strand: Reverse

Name: cynX [H]

Synonym: Bcep18194_A4832

Alternate gene names: 78066302

Gene position: 1849317-1848139 (Counterclockwise)

Preceding gene: 78066306

Following gene: 78066300

Centisome position: 50.06

GC content: 72.94

Gene sequence:

>1179_bases
ATGAATCGCTTCACTTCCCCCGGATGGCGGCTCGCCGCCATCGTCCTTGTCGGGCTGAACCTGCGGCCGGCGCTCGCCGC
GGTCGGCCCGCTGCTCGACATGATCCAGCGCACGACCGGCATCAGCGACGGCGCGGCCAGCCTGCTGACGACGATCCCGA
TCCTGCTGATGGGGCTCGGCGCGCTGAGTGCGCGGCGCCTGCAGCGCCTGACCGGCATCGCGGGCGGCGTCTGGCTCGGC
GTCGCGCTGATCGGGCTGGCCTGCGTGTCGCGCGTCGGCGCGCAGCACGCATGGCTGCTGCTCGCGAGCGCCTGCTGCGC
AGGCGTCGGGATCGCGATGGTGCAGGCGCTGCTGCCTGGCTTCGTGAAGGCGAATTTCTCGACGCGGATCGGCGGGGCGA
TGGGCGTCTATTCGACGTCGATCATGGGCGGCGCCGTGCTCGCGAGCGTTATCGCGCCGTTTGCCGCGGCGCGCTGGGGC
TGGCTTCCCGCGCTCGCGGGCTGGGCGCTGCCGGCCGCGGTGGCTGCTCTGGCCTGGCCGCTGGCCAGTCGCGGCGGCGA
CGCATTCGCCGCCGGGCCGACGTCGGCGTCGAACACGCAGCCGTCGCGCTCGCCGCGCGCGTGGCGGCTCGCGCTGTTCT
TCGGCATCGCGACGGGCGCGTACACGCTCGTGCTCGCGTGGCTGCCGCCGTACTACATGCGGCTCGGCTGGTCGCCGACG
GCGGCCGGCAGCCTGCTCGGCGGCGTGACGCTCGCGGAAGTCGTCGCGGGGCTGACGATCTCGGCGATGATCGACCGCCT
GCCCGATCGCCGGCCCGCGCTGCATGCGGCGATCGCGTCGCTGTTCGTCGGCTTGCTGGTGATGCTGGTCGCACCGGAAG
CGCTTGCGCTACCGGCCGCGCTGTTGATGGGTGCGGGGATCGGCGCGCTGTTTCCGCTGTCGCTGATCGTCACCGTTGAC
CACGCCGCGACACCGGCCGATGCCGCGTCGCTGACGGGGTTCGTGCAGGGCATCGGCTACCTGATCGCCGGGCTGTTCCC
GTTCGCGGCGGGCATCGTGCGCCAGCACCTCGCGGACCTGTCACCCGCGTGGATCGCGATGGCCTGCCTGTGTGTCGCGC
TGTTCGCGCTGGCGGCGGGGTTTGCACCGAAGCGGGTGCTGCACGTCGCGCGTGCGTAG

Upstream 100 bases:

>100_bases
GACGTCGAGATAAATCACCGTTTATCTTGATGTCGAGATACTTTACATGAAAACGCGCGGCGCCTCACCGGGGTCGCGCA
CCGATATCGAGGGTCTTGCA

Downstream 100 bases:

>100_bases
CGCGTTTTGCCCCGCCGCGATCGGATAAGGCGTTGTTCGGGATCTGACTGACTGAGCGCGGCGCGCGGCGTGCCGGTGCA
CCGCGCCTGCGTCAGCCACC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; Cyanate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MNRFTSPGWRLAAIVLVGLNLRPALAAVGPLLDMIQRTTGISDGAASLLTTIPILLMGLGALSARRLQRLTGIAGGVWLG
VALIGLACVSRVGAQHAWLLLASACCAGVGIAMVQALLPGFVKANFSTRIGGAMGVYSTSIMGGAVLASVIAPFAAARWG
WLPALAGWALPAAVAALAWPLASRGGDAFAAGPTSASNTQPSRSPRAWRLALFFGIATGAYTLVLAWLPPYYMRLGWSPT
AAGSLLGGVTLAEVVAGLTISAMIDRLPDRRPALHAAIASLFVGLLVMLVAPEALALPAALLMGAGIGALFPLSLIVTVD
HAATPADAASLTGFVQGIGYLIAGLFPFAAGIVRQHLADLSPAWIAMACLCVALFALAAGFAPKRVLHVARA

Sequences:

>Translated_392_residues
MNRFTSPGWRLAAIVLVGLNLRPALAAVGPLLDMIQRTTGISDGAASLLTTIPILLMGLGALSARRLQRLTGIAGGVWLG
VALIGLACVSRVGAQHAWLLLASACCAGVGIAMVQALLPGFVKANFSTRIGGAMGVYSTSIMGGAVLASVIAPFAAARWG
WLPALAGWALPAAVAALAWPLASRGGDAFAAGPTSASNTQPSRSPRAWRLALFFGIATGAYTLVLAWLPPYYMRLGWSPT
AAGSLLGGVTLAEVVAGLTISAMIDRLPDRRPALHAAIASLFVGLLVMLVAPEALALPAALLMGAGIGALFPLSLIVTVD
HAATPADAASLTGFVQGIGYLIAGLFPFAAGIVRQHLADLSPAWIAMACLCVALFALAAGFAPKRVLHVARA
>Mature_392_residues
MNRFTSPGWRLAAIVLVGLNLRPALAAVGPLLDMIQRTTGISDGAASLLTTIPILLMGLGALSARRLQRLTGIAGGVWLG
VALIGLACVSRVGAQHAWLLLASACCAGVGIAMVQALLPGFVKANFSTRIGGAMGVYSTSIMGGAVLASVIAPFAAARWG
WLPALAGWALPAAVAALAWPLASRGGDAFAAGPTSASNTQPSRSPRAWRLALFFGIATGAYTLVLAWLPPYYMRLGWSPT
AAGSLLGGVTLAEVVAGLTISAMIDRLPDRRPALHAAIASLFVGLLVMLVAPEALALPAALLMGAGIGALFPLSLIVTVD
HAATPADAASLTGFVQGIGYLIAGLFPFAAGIVRQHLADLSPAWIAMACLCVALFALAAGFAPKRVLHVARA

Specific function: This protein is part of an active transport system that transports exogenous cyanate into E.coli cells [H]

COG id: COG2807

COG function: function code P; Cyanate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786536, Length=379, Percent_Identity=36.9393139841689, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1788092, Length=383, Percent_Identity=30.2872062663185, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004747
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 39917; Mature: 39917

Theoretical pI: Translated: 11.19; Mature: 11.19

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFTSPGWRLAAIVLVGLNLRPALAAVGPLLDMIQRTTGISDGAASLLTTIPILLMGLG
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ALSARRLQRLTGIAGGVWLGVALIGLACVSRVGAQHAWLLLASACCAGVGIAMVQALLPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVKANFSTRIGGAMGVYSTSIMGGAVLASVIAPFAAARWGWLPALAGWALPAAVAALAWP
HHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LASRGGDAFAAGPTSASNTQPSRSPRAWRLALFFGIATGAYTLVLAWLPPYYMRLGWSPT
HHHCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCH
AAGSLLGGVTLAEVVAGLTISAMIDRLPDRRPALHAAIASLFVGLLVMLVAPEALALPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LLMGAGIGALFPLSLIVTVDHAATPADAASLTGFVQGIGYLIAGLFPFAAGIVRQHLADL
HHHHCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SPAWIAMACLCVALFALAAGFAPKRVLHVARA
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MNRFTSPGWRLAAIVLVGLNLRPALAAVGPLLDMIQRTTGISDGAASLLTTIPILLMGLG
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ALSARRLQRLTGIAGGVWLGVALIGLACVSRVGAQHAWLLLASACCAGVGIAMVQALLPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVKANFSTRIGGAMGVYSTSIMGGAVLASVIAPFAAARWGWLPALAGWALPAAVAALAWP
HHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LASRGGDAFAAGPTSASNTQPSRSPRAWRLALFFGIATGAYTLVLAWLPPYYMRLGWSPT
HHHCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCH
AAGSLLGGVTLAEVVAGLTISAMIDRLPDRRPALHAAIASLFVGLLVMLVAPEALALPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LLMGAGIGALFPLSLIVTVDHAATPADAASLTGFVQGIGYLIAGLFPFAAGIVRQHLADL
HHHHCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SPAWIAMACLCVALFALAAGFAPKRVLHVARA
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Cyanate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Cyanate [Periplasm] = Proton [Cytoplasm] + Cyanate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3049588; 9278503 [H]