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The map label for this gene is cobM [H]

Identifier: 78066299

GI number: 78066299

Start: 1845729

End: 1846457

Strand: Direct

Name: cobM [H]

Synonym: Bcep18194_A4829

Alternate gene names: 78066299

Gene position: 1845729-1846457 (Clockwise)

Preceding gene: 78066298

Following gene: 78066301

Centisome position: 49.96

GC content: 69.14

Gene sequence:

>729_bases
ATGACGGTGTATTTCATCGGCGCGGGCCCCGGCGACCCGGAGCTGATCACGGTGAAGGGCCAGCGCCTCGTACGCACGTG
CCCGGTGATCCTGTATGCGGGTTCGCTGGTGCCGGCCGCCGTGCTCGACGGCCATCGCGCGGAGCAGGTCGTCAATACGG
CCGAGCTCGACCTCGACGCCATCGTCGCGCTGCTCGCCGGCGCGCACGCGAAAGGGCAAGACGTCGCGCGCGTGCATTCG
GGCGACCCGTCGCTGTACGGCGCGATCGGCGAGCAGATTCGCCGATTGAAAGCGCTCGGGATTCCATATGAAATCGTGCC
CGGCGTAACGGCCACGGCTGCGTGCGCGGCGACGCTCGGCGTCGAGCTAACGCTGCCCGGCGTCGCGCAGACGGTGATCC
TCACGCGCTTCGCGGGCAAGACGACAATGCCGGAAGGCGAAGCGCTCGGCTCGCTCGCCGCGCACCGCGCGACGCTCGCG
ATTCATCTCGGCGTGCGCCATCTCGCCCGCATCGTCGACGAAGTGCTGCCGCATTACGGTGCCGATTGCCCGGTCGCGGT
GATCTATCGCGCAAGCTGGCCCGATGAAGCCCGCGTGACCGGCACGCTCGCCGACATCGTCGGCAAGGTGCAGGGCACGC
AGATCGAGCGCACGGCGCTGATCCTGATCGGGCGCGTGCTCGACGCCGAAGGGTTCGCGGATTCGACGCTGTACGCGAGC
GCGGGCTGA

Upstream 100 bases:

>100_bases
GCATTCGATTCGGCTACGGCGCTCATCGACGCGCTCGATCCGGCCACGCGCACGTGACGCCACGCGGCGGATCATTCAAT
GAATTGACGGAGATTTTTCG

Downstream 100 bases:

>100_bases
TCACGCACGGGCCGGCCCGGGTTCGGAACGGCGTTCGCGCAGGTGCGTGTAGAGCGCCGCGCCGATCGTGATTGCGCCGC
CGACGAAGTAGATCGGCGAC

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTVYFIGAGPGDPELITVKGQRLVRTCPVILYAGSLVPAAVLDGHRAEQVVNTAELDLDAIVALLAGAHAKGQDVARVHS
GDPSLYGAIGEQIRRLKALGIPYEIVPGVTATAACAATLGVELTLPGVAQTVILTRFAGKTTMPEGEALGSLAAHRATLA
IHLGVRHLARIVDEVLPHYGADCPVAVIYRASWPDEARVTGTLADIVGKVQGTQIERTALILIGRVLDAEGFADSTLYAS
AG

Sequences:

>Translated_242_residues
MTVYFIGAGPGDPELITVKGQRLVRTCPVILYAGSLVPAAVLDGHRAEQVVNTAELDLDAIVALLAGAHAKGQDVARVHS
GDPSLYGAIGEQIRRLKALGIPYEIVPGVTATAACAATLGVELTLPGVAQTVILTRFAGKTTMPEGEALGSLAAHRATLA
IHLGVRHLARIVDEVLPHYGADCPVAVIYRASWPDEARVTGTLADIVGKVQGTQIERTALILIGRVLDAEGFADSTLYAS
AG
>Mature_241_residues
TVYFIGAGPGDPELITVKGQRLVRTCPVILYAGSLVPAAVLDGHRAEQVVNTAELDLDAIVALLAGAHAKGQDVARVHSG
DPSLYGAIGEQIRRLKALGIPYEIVPGVTATAACAATLGVELTLPGVAQTVILTRFAGKTTMPEGEALGSLAAHRATLAI
HLGVRHLARIVDEVLPHYGADCPVAVIYRASWPDEARVTGTLADIVGKVQGTQIERTALILIGRVLDAEGFADSTLYASA
G

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=256, Percent_Identity=30.859375, Blast_Score=97, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6322922, Length=223, Percent_Identity=26.457399103139, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 25141; Mature: 25010

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00839 SUMT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYFIGAGPGDPELITVKGQRLVRTCPVILYAGSLVPAAVLDGHRAEQVVNTAELDLDA
CEEEEEECCCCCCCEEEECCCHHHHHCCHHEEECCCHHHHHHCCHHHHHHHHHHHCCHHH
IVALLAGAHAKGQDVARVHSGDPSLYGAIGEQIRRLKALGIPYEIVPGVTATAACAATLG
HHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHC
VELTLPGVAQTVILTRFAGKTTMPEGEALGSLAAHRATLAIHLGVRHLARIVDEVLPHYG
EEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCC
ADCPVAVIYRASWPDEARVTGTLADIVGKVQGTQIERTALILIGRVLDAEGFADSTLYAS
CCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEC
AG
CC
>Mature Secondary Structure 
TVYFIGAGPGDPELITVKGQRLVRTCPVILYAGSLVPAAVLDGHRAEQVVNTAELDLDA
EEEEEECCCCCCCEEEECCCHHHHHCCHHEEECCCHHHHHHCCHHHHHHHHHHHCCHHH
IVALLAGAHAKGQDVARVHSGDPSLYGAIGEQIRRLKALGIPYEIVPGVTATAACAATLG
HHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHC
VELTLPGVAQTVILTRFAGKTTMPEGEALGSLAAHRATLAIHLGVRHLARIVDEVLPHYG
EEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCC
ADCPVAVIYRASWPDEARVTGTLADIVGKVQGTQIERTALILIGRVLDAEGFADSTLYAS
CCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]