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The map label for this gene is lgrB [H]

Identifier: 78066257

GI number: 78066257

Start: 1796604

End: 1801595

Strand: Direct

Name: lgrB [H]

Synonym: Bcep18194_A4787

Alternate gene names: 78066257

Gene position: 1796604-1801595 (Clockwise)

Preceding gene: 78066256

Following gene: 78066258

Centisome position: 48.63

GC content: 71.71

Gene sequence:

>4992_bases
ATGACGAAGGTTCAACCCGACTGGCTCGCGCTCGCGACGCGCTTCGCGCAACTGCCCGACGCGCAGCGAGCCGTCTTCAT
CGACAAGCTCGGCGCGGCCGGCATCGACTTCCGCGTGCTGCCGATTCCGCCACGCACGCCACGCAGCGACCGCGTGCCGG
CGTCGTTCGCGCAGACTCGGCTGTGGCTGCACGCGCGGCTGATCGACGCGCCCGACGCGTATCACATCACCGAGCGCCTG
GCGCTGACGGGCCCGCTCGACGCGCATGCGCTGCGTCTTGCGTGCGACGCGCTGATCGCGCGCCACGAGGCGCTGCGCAC
GACCTTCGACGAAGCGCAGGACGGTGTCGCGCAAACGATCCACGCGCCGTTGCGCTGCCCGTGGCGCGAAACCGATCTCG
AAGCAGTGCCGGATGCACAACGCGCGGCGCGCGCGGAGGCCGTCGCGACGGCCGATGAAGCCGAGCCGTTCGATCTCGGT
GCGGCGCCGCTGGTCCGCGCGCACCTCGTGCGCTTCGATGCGACGCATCACTGGCTCGCGCTGACCGTGCATCACATCGT
GTCGGACGGCTGGTCGTCGGGCGTGATGCTCGAGGAACTCGCGGCGTTCTATCGTGCGTATGCGTCCGACCGGCCGGTGC
CGCTCGCGCCGCTGCCGATCCAGTACGCCGACTACGCGCTGTGGCAGCGCCGCTGGCTCGACGCCGGCGAGCGTGACCGC
CAGCTCGCGTTCTGGCGCGAACGGCTCGATCCGCAACGCGGCGTGCTGGCGCTGCCGGGCGCGGCTGCTCGACCCGCACG
CCGCAGTGCGCGCGGCGCACGTCATGTGTTTTCGCTCGACGCGCGCATCGGCGTGCAACTGCGCGCCTTCGCGGCTGCCT
CGGGCGCCACGCCGTTCGCGGTGCTGCTCGCCGCGCTCGATGCGCTGCTGGCGCGCGCGACCGGCGACGCGCGCATCTGC
GTCGGCGTGCCGGCCGCGAACCGCGAACGCGCGGAAGTCGCCGGCCTGATCGGCTTCTTCGTCAACACGCTTGCGATCGA
CGTCGAGGTGCCCGCGCACGGCGATTTCTCGTCGCTGGTCGCGCGCACGCAGCGTGCGCTCGTCGACGCGCAGATGCACC
AGGACGTGCCGTTCGAGCAGGTGGTCGACGCGCTCGGCGTGCCGCGCAGCGCGAGCCACCATCCGCTGTTCCAGGTGATG
GCCGCGTACGGCGAGCGCCGCGCGCTGCCGGCGCTCGGCACGGCAGCGGCCGCGTTGCTGCCGTCGGGCACGCCATCCGC
GAAATTCGACCTGACGCTCTCGGTCGAAGCGACGCCGGACGGCACGTTCGACGCCGTATTCATCTACGCGCTCGACCTGT
TCGAAGCGGACGCGATTTCACGGCTGGCCGCGCGCTTCGTCACGCTGCTGGCCGATGCGCTCGCGCGCCCGGACATGCCG
GTCGGCGATCTCGACTGGCTGCCTGCCGCCGAGCGCGAGCAGCTCTTCGCATGGAACGCGCCGGCAGGCGCCACCGAATC
CGAACCGTTCGTGCCCGTTCATGCCCGCATCGCCGCGCATGCTCAGGCACGGCCCGATGCACGCGGCGTCGCCGACATCG
AGCGTGCGCTGACGCGCCGTGAAGTCGATGCACGCGCGGCACGGCTGGCGCGCCATCTCGTGGCGGCCGGCGTACGACCG
GAAATGCGCGTCGGCGTCGCGCTGCAGCGCTCGGTCGACCTGCTCGTCGCGCTGATCGCGGTGCTGAAGTCGGGCGCCGC
GTTCGTGCCGCTCGATCCTGCGCATCCGCGCGAACGGCTCGCACAGATCGTCGGCGATGCGAACATCGCGCACGTGCTGA
CCGATGGCGCGAGCGCCGCGTCGCTGCCCGAGCTGCCGGATCTGCGTGTGTGGCGCGCCGATGAAGTCGATGCACTCGAC
GAAGCCGCGCACGTCGTGCTACCGGACGTGCTGCCGGGCCACGCGGCCTATGCGATCTACACGTCGGGCTCGACCGGCAA
GCCGAAGGGCGTGATCGTCGACCATGCGTCGTTCGCGCTGCATTGCGCGGCGATCGCCGAGCGCTACGGCGCGGGCGAGA
GCGACGTGTTCCTGCTGTTCCAGTCGGTCAACTTCGACGGCGCGCACGAAGGCTGGTTTTCGCAATACATGTCGGGCGCC
GCCGTGTCGGTGACGGCCGACGTGCTGTGGCCGCCCGCGCAGACCTGCGCGATGATGGTCCGCGACGGCGTGACGATGAC
CTACGTGCCGCCTGGTTGTGCCGCACAGCTCGCCGAATGGGCGCTCGCGCATGGCGCACCGCCGACGCTGCGTTCGCTGA
CCGTCGGTGGCGAGGCGACGTCGCGCGAAGCGTTCGCGATGCTGCGCCGCGCACTGCCGAACGTGCGCGTGGTCAACGGC
TACGGGCCGACCGAGACGGTCATCACGCCGACGCTGTGGATGTTCCGCCCCGGCGACGATCTCGCGAAGCTCGGCGACGC
CGCGTACCTGCCGATCGGCACGCTGGTCGGCGCACGCACCGCGCACGTGCTCGACGAACGCCTGCATCCGCTGCCGGTCG
GCGTGATCGGCGAACTGTACCTGGGCGGCGAAGGGATCGGCGTCGCGCGCGGCTATCTCGACCGCCCGGCGCTGACGGCC
GAGCGCTTCGTGCCCGATCCGTACGGTGCGCCGGGCGCGCGGCTGTACCGCACGGGCGACCTCGTGCGGCGTCGCGCGGA
CGGCGTGTTCGACTTCATCGGCCGCGTCGACCACCAGGTGAAGCTGCGCGGGCTGCGCATCGAACTCGGCGAGATCGAGG
CCCAGCTTGCCGCGCACGAGGCAGTGCGCGAAGCATGCGCGGTCGTGCACGGGCAGGGCGCACTCGCGCAGCTCGTCGCG
TATGTCGAGCTGACCGCCGACGCACAGGCGGCCGCGCAGCCGGTCGAAGCCGCTACGCTCGACGCGCATCTGCGCCGCAC
GCTGCCCGATTACATGGTGCCCGCGCAGCTGATCGTGCTCGACGCGCTGCCGCGCAACGCGAACAGCAAGGTCGACCGAG
CACGGTTGCCGGCGCCGGTGCGGGTCGAACGCGCGTACGAAGCGCCGCACGACGGCGACGAAGCCGCGCTCGCAGCGATC
TGGTGCGACGTGCTGAATCTCGAACGCGTGGGCCGTGGCGATCACTTCTTCGATCTCGGCGGCCATTCGCTCGCCGCCGT
GCGCGTCGCGACGCGCGTGGCCGAGCGGCTCGGCCGCGACGTGCCGGTGCGCGCGCTGTTCGAAGCGCCGGTGCTTGCGC
AGTATGCGTTGCAGGTGGCCGATGCGCCGCGCGCCGCGCACGCCGGTGCGGCTGCGCCGGGCGTTGCCGTCGCCAAACCG
GACGCACACGGCGTGTGGCCGCTGTCACCGGCGCAGCTCGGCCTGTGGTTCCTGTGGCGCGCGCAGCCGGACAGCGCCGC
GTACAACATTCCGGTCGCGCTGCGTGTGCGCGGCCCGCTCGACGTCGATGCGCTGCGTGCGGCGTTCACGGATGCGGCAG
CCGTGCATCCGGCGCTGCGCGCGCGGCTCGTTGCTCGCGACGGTGTTTTGCCAGGCCAGCGGATCGACGCGGCGATGCAG
GTCGAACTGCCGGTCGTCGACCTGGCGATGCAGCCCGATGCGCTCGCTCGCGCCGCAGCACTGACCGACGAAGATGCGCT
CACGCCATTCGACCTCGCAGCCGATGCGCCGCTGTGGCGTGCGCGCGTGCTGCGGCTCGACGCAGAAGACCACGTGCTGT
CGGTGACGATTCATCACATCGTGTCGGATGGCGAATCGATCGAGCTGTGGCTCGACGCGGTTCGTGCACGCTATGTCGCC
CGCGTACAGGGCAACGCCGTGCCGGCCGCAGCAATTGCCCAACCGGTCGTACCGCTCGTGTTGCCCGCACCGTCCCATCC
GGCCCGCGTCGCCTACTGGCGCGACGCGCTGGCCGACCTGCCGGCGCGCGTGCTGCCGCAGCGCGCGGACGCGCCGGCCG
TGCCGCAATGGCGTGCGGCCCGCATCGCGTTCGAATTCGACGGCGCGCTGATCCGCGCCGCGCGCGACACGGCGTCGGCC
GCGCACGCGACGCTGCCGATGCTGCTGCACGCGGCGCTCAACACCGCGCTGTTCCGCACGACGGGGGCGTCTGACCAGCC
GGTCGGCGTGCTCGCGTCGACGCGCGAGCTGACGGGCGATGCGGCTCGCGACGCGCTCGGCCTCTTCATCAATTCGGTCG
TCGTGCGCACGCAGCTCGACCCGGCCGCGCGTCGTACGGACGTGCTCGCCCAAGTGCGCGACATGGCGCTGATGGCCTAT
GCACACGCCGACGTGCCGTTCGCGGACGTCGTCGCGGCGCTGCGCGCACCGCGTGCCGCGCAGGCCAATCCGCTGTTCCA
GGTGATGTTCAACTACCTGCGCCCGACCGGTGCCGCGGCGCGCGACTGGGCCGGCCTGTCGCTGGCCGGATTCGACGACG
TGCGCCATCGCGTCGTGTTCACGCTGGAGCTGGACGTCGTCGAGCATCCGGATGGCCGCGTGAGCGCCGCCTTCTCGTAT
GCGGATGAATTGCTCGATCGCGGTTTCGTCGATGCGCTCGTCGATGTCTATCACGACGAAGTCGCGCGTTTCGCCGGCGC
GTCGGAAGCGGCGCTCGGCGCGCCCGACAAACATGCCATTGCGCAAGCGTCGCAGCGCGCGCAGGCGGAAGGCAATGCAC
GCGCGGCAACGCCGTCCCGTGCGCCGCACGCGGCCGCCTCGCTCGCGGCGCTGTGGTCCGACACGTTCGCAGCGGCCGCG
CCCGAAGCGGACGCCAACCTGTTCGAAGCCGGCGCGACCTCGTTCGACGTCGTGCGCTTCGTCGACGCGGCGAGCCGTGC
CGGTCATGCGCTGACGGTTGCCGACCTGTTCGCGTCGCCAACGCTTGCGGCACTCGGCGCGCGACTCGATGCACCCGCGG
AAACGGGACAGGAGGCGCGCCATGCTGGCTGA

Upstream 100 bases:

>100_bases
GGAGGCGATCGACGCGGCCTGTGCGGCGCGCGGCGAAACCGACGCGGCGAGCGCGATCGATGCGCTGCTCGGCGAACTGG
AAACCCAATAAGGACGACGG

Downstream 100 bases:

>100_bases
AGTGCGTCCGGACGGATTCACGATGCTCGATACCTACCGCCTCGCATTCTCGGACGGCCTGTTCGCCGTGCGCGACGGCG
CAGAGATTCGCGTTGCGCAG

Product: amino acid adenylation

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1663; Mature: 1662

Protein sequence:

>1663_residues
MTKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTRLWLHARLIDAPDAYHITERL
ALTGPLDAHALRLACDALIARHEALRTTFDEAQDGVAQTIHAPLRCPWRETDLEAVPDAQRAARAEAVATADEAEPFDLG
AAPLVRAHLVRFDATHHWLALTVHHIVSDGWSSGVMLEELAAFYRAYASDRPVPLAPLPIQYADYALWQRRWLDAGERDR
QLAFWRERLDPQRGVLALPGAAARPARRSARGARHVFSLDARIGVQLRAFAAASGATPFAVLLAALDALLARATGDARIC
VGVPAANRERAEVAGLIGFFVNTLAIDVEVPAHGDFSSLVARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVM
AAYGERRALPALGTAAAALLPSGTPSAKFDLTLSVEATPDGTFDAVFIYALDLFEADAISRLAARFVTLLADALARPDMP
VGDLDWLPAAEREQLFAWNAPAGATESEPFVPVHARIAAHAQARPDARGVADIERALTRREVDARAARLARHLVAAGVRP
EMRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERLAQIVGDANIAHVLTDGASAASLPELPDLRVWRADEVDALD
EAAHVVLPDVLPGHAAYAIYTSGSTGKPKGVIVDHASFALHCAAIAERYGAGESDVFLLFQSVNFDGAHEGWFSQYMSGA
AVSVTADVLWPPAQTCAMMVRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEATSREAFAMLRRALPNVRVVNG
YGPTETVITPTLWMFRPGDDLAKLGDAAYLPIGTLVGARTAHVLDERLHPLPVGVIGELYLGGEGIGVARGYLDRPALTA
ERFVPDPYGAPGARLYRTGDLVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHEAVREACAVVHGQGALAQLVA
YVELTADAQAAAQPVEAATLDAHLRRTLPDYMVPAQLIVLDALPRNANSKVDRARLPAPVRVERAYEAPHDGDEAALAAI
WCDVLNLERVGRGDHFFDLGGHSLAAVRVATRVAERLGRDVPVRALFEAPVLAQYALQVADAPRAAHAGAAAPGVAVAKP
DAHGVWPLSPAQLGLWFLWRAQPDSAAYNIPVALRVRGPLDVDALRAAFTDAAAVHPALRARLVARDGVLPGQRIDAAMQ
VELPVVDLAMQPDALARAAALTDEDALTPFDLAADAPLWRARVLRLDAEDHVLSVTIHHIVSDGESIELWLDAVRARYVA
RVQGNAVPAAAIAQPVVPLVLPAPSHPARVAYWRDALADLPARVLPQRADAPAVPQWRAARIAFEFDGALIRAARDTASA
AHATLPMLLHAALNTALFRTTGASDQPVGVLASTRELTGDAARDALGLFINSVVVRTQLDPAARRTDVLAQVRDMALMAY
AHADVPFADVVAALRAPRAAQANPLFQVMFNYLRPTGAAARDWAGLSLAGFDDVRHRVVFTLELDVVEHPDGRVSAAFSY
ADELLDRGFVDALVDVYHDEVARFAGASEAALGAPDKHAIAQASQRAQAEGNARAATPSRAPHAAASLAALWSDTFAAAA
PEADANLFEAGATSFDVVRFVDAASRAGHALTVADLFASPTLAALGARLDAPAETGQEARHAG

Sequences:

>Translated_1663_residues
MTKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTRLWLHARLIDAPDAYHITERL
ALTGPLDAHALRLACDALIARHEALRTTFDEAQDGVAQTIHAPLRCPWRETDLEAVPDAQRAARAEAVATADEAEPFDLG
AAPLVRAHLVRFDATHHWLALTVHHIVSDGWSSGVMLEELAAFYRAYASDRPVPLAPLPIQYADYALWQRRWLDAGERDR
QLAFWRERLDPQRGVLALPGAAARPARRSARGARHVFSLDARIGVQLRAFAAASGATPFAVLLAALDALLARATGDARIC
VGVPAANRERAEVAGLIGFFVNTLAIDVEVPAHGDFSSLVARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVM
AAYGERRALPALGTAAAALLPSGTPSAKFDLTLSVEATPDGTFDAVFIYALDLFEADAISRLAARFVTLLADALARPDMP
VGDLDWLPAAEREQLFAWNAPAGATESEPFVPVHARIAAHAQARPDARGVADIERALTRREVDARAARLARHLVAAGVRP
EMRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERLAQIVGDANIAHVLTDGASAASLPELPDLRVWRADEVDALD
EAAHVVLPDVLPGHAAYAIYTSGSTGKPKGVIVDHASFALHCAAIAERYGAGESDVFLLFQSVNFDGAHEGWFSQYMSGA
AVSVTADVLWPPAQTCAMMVRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEATSREAFAMLRRALPNVRVVNG
YGPTETVITPTLWMFRPGDDLAKLGDAAYLPIGTLVGARTAHVLDERLHPLPVGVIGELYLGGEGIGVARGYLDRPALTA
ERFVPDPYGAPGARLYRTGDLVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHEAVREACAVVHGQGALAQLVA
YVELTADAQAAAQPVEAATLDAHLRRTLPDYMVPAQLIVLDALPRNANSKVDRARLPAPVRVERAYEAPHDGDEAALAAI
WCDVLNLERVGRGDHFFDLGGHSLAAVRVATRVAERLGRDVPVRALFEAPVLAQYALQVADAPRAAHAGAAAPGVAVAKP
DAHGVWPLSPAQLGLWFLWRAQPDSAAYNIPVALRVRGPLDVDALRAAFTDAAAVHPALRARLVARDGVLPGQRIDAAMQ
VELPVVDLAMQPDALARAAALTDEDALTPFDLAADAPLWRARVLRLDAEDHVLSVTIHHIVSDGESIELWLDAVRARYVA
RVQGNAVPAAAIAQPVVPLVLPAPSHPARVAYWRDALADLPARVLPQRADAPAVPQWRAARIAFEFDGALIRAARDTASA
AHATLPMLLHAALNTALFRTTGASDQPVGVLASTRELTGDAARDALGLFINSVVVRTQLDPAARRTDVLAQVRDMALMAY
AHADVPFADVVAALRAPRAAQANPLFQVMFNYLRPTGAAARDWAGLSLAGFDDVRHRVVFTLELDVVEHPDGRVSAAFSY
ADELLDRGFVDALVDVYHDEVARFAGASEAALGAPDKHAIAQASQRAQAEGNARAATPSRAPHAAASLAALWSDTFAAAA
PEADANLFEAGATSFDVVRFVDAASRAGHALTVADLFASPTLAALGARLDAPAETGQEARHAG
>Mature_1662_residues
TKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTRLWLHARLIDAPDAYHITERLA
LTGPLDAHALRLACDALIARHEALRTTFDEAQDGVAQTIHAPLRCPWRETDLEAVPDAQRAARAEAVATADEAEPFDLGA
APLVRAHLVRFDATHHWLALTVHHIVSDGWSSGVMLEELAAFYRAYASDRPVPLAPLPIQYADYALWQRRWLDAGERDRQ
LAFWRERLDPQRGVLALPGAAARPARRSARGARHVFSLDARIGVQLRAFAAASGATPFAVLLAALDALLARATGDARICV
GVPAANRERAEVAGLIGFFVNTLAIDVEVPAHGDFSSLVARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVMA
AYGERRALPALGTAAAALLPSGTPSAKFDLTLSVEATPDGTFDAVFIYALDLFEADAISRLAARFVTLLADALARPDMPV
GDLDWLPAAEREQLFAWNAPAGATESEPFVPVHARIAAHAQARPDARGVADIERALTRREVDARAARLARHLVAAGVRPE
MRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERLAQIVGDANIAHVLTDGASAASLPELPDLRVWRADEVDALDE
AAHVVLPDVLPGHAAYAIYTSGSTGKPKGVIVDHASFALHCAAIAERYGAGESDVFLLFQSVNFDGAHEGWFSQYMSGAA
VSVTADVLWPPAQTCAMMVRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEATSREAFAMLRRALPNVRVVNGY
GPTETVITPTLWMFRPGDDLAKLGDAAYLPIGTLVGARTAHVLDERLHPLPVGVIGELYLGGEGIGVARGYLDRPALTAE
RFVPDPYGAPGARLYRTGDLVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHEAVREACAVVHGQGALAQLVAY
VELTADAQAAAQPVEAATLDAHLRRTLPDYMVPAQLIVLDALPRNANSKVDRARLPAPVRVERAYEAPHDGDEAALAAIW
CDVLNLERVGRGDHFFDLGGHSLAAVRVATRVAERLGRDVPVRALFEAPVLAQYALQVADAPRAAHAGAAAPGVAVAKPD
AHGVWPLSPAQLGLWFLWRAQPDSAAYNIPVALRVRGPLDVDALRAAFTDAAAVHPALRARLVARDGVLPGQRIDAAMQV
ELPVVDLAMQPDALARAAALTDEDALTPFDLAADAPLWRARVLRLDAEDHVLSVTIHHIVSDGESIELWLDAVRARYVAR
VQGNAVPAAAIAQPVVPLVLPAPSHPARVAYWRDALADLPARVLPQRADAPAVPQWRAARIAFEFDGALIRAARDTASAA
HATLPMLLHAALNTALFRTTGASDQPVGVLASTRELTGDAARDALGLFINSVVVRTQLDPAARRTDVLAQVRDMALMAYA
HADVPFADVVAALRAPRAAQANPLFQVMFNYLRPTGAAARDWAGLSLAGFDDVRHRVVFTLELDVVEHPDGRVSAAFSYA
DELLDRGFVDALVDVYHDEVARFAGASEAALGAPDKHAIAQASQRAQAEGNARAATPSRAPHAAASLAALWSDTFAAAAP
EADANLFEAGATSFDVVRFVDAASRAGHALTVADLFASPTLAALGARLDAPAETGQEARHAG

Specific function: Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids [H

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=628, Percent_Identity=23.7261146496815, Blast_Score=106, Evalue=2e-22,
Organism=Homo sapiens, GI38505220, Length=372, Percent_Identity=26.3440860215054, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI28416953, Length=553, Percent_Identity=24.7739602169982, Blast_Score=78, Evalue=8e-14,
Organism=Homo sapiens, GI42544132, Length=368, Percent_Identity=22.8260869565217, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI58082049, Length=514, Percent_Identity=23.1517509727626, Blast_Score=74, Evalue=2e-12,
Organism=Homo sapiens, GI157311624, Length=510, Percent_Identity=23.1372549019608, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI157311622, Length=510, Percent_Identity=23.1372549019608, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI122937307, Length=372, Percent_Identity=24.4623655913978, Blast_Score=69, Evalue=3e-11,
Organism=Escherichia coli, GI1786801, Length=1066, Percent_Identity=29.7373358348968, Blast_Score=315, Evalue=1e-86,
Organism=Escherichia coli, GI1790505, Length=638, Percent_Identity=23.8244514106583, Blast_Score=81, Evalue=4e-16,
Organism=Escherichia coli, GI145693145, Length=521, Percent_Identity=23.6084452975048, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786810, Length=530, Percent_Identity=25.4716981132075, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI221142682, Length=519, Percent_Identity=21.9653179190751, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17550940, Length=1069, Percent_Identity=20.112254443405, Blast_Score=130, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17556356, Length=561, Percent_Identity=24.2424242424242, Blast_Score=123, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17558820, Length=527, Percent_Identity=24.0986717267552, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32563687, Length=510, Percent_Identity=23.921568627451, Blast_Score=89, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71983001, Length=376, Percent_Identity=28.7234042553192, Blast_Score=69, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71982997, Length=372, Percent_Identity=29.3010752688172, Blast_Score=68, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=782, Percent_Identity=25.5754475703325, Blast_Score=223, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6323182, Length=423, Percent_Identity=26.7139479905437, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24648676, Length=616, Percent_Identity=27.1103896103896, Blast_Score=149, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24581924, Length=370, Percent_Identity=25.9459459459459, Blast_Score=79, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 177494; Mature: 177363

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTR
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHH
LWLHARLIDAPDAYHITERLALTGPLDAHALRLACDALIARHEALRTTFDEAQDGVAQTI
HHHHEEEECCCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAPLRCPWRETDLEAVPDAQRAARAEAVATADEAEPFDLGAAPLVRAHLVRFDATHHWLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHH
LTVHHIVSDGWSSGVMLEELAAFYRAYASDRPVPLAPLPIQYADYALWQRRWLDAGERDR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCH
QLAFWRERLDPQRGVLALPGAAARPARRSARGARHVFSLDARIGVQLRAFAAASGATPFA
HHHHHHHHCCCCCCEEECCCCCCCCHHHHHCCCHHEEEECCCCCEEEEEEECCCCCCHHH
VLLAALDALLARATGDARICVGVPAANRERAEVAGLIGFFVNTLAIDVEVPAHGDFSSLV
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHH
ARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVMAAYGERRALPALGTAAAALL
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHC
PSGTPSAKFDLTLSVEATPDGTFDAVFIYALDLFEADAISRLAARFVTLLADALARPDMP
CCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VGDLDWLPAAEREQLFAWNAPAGATESEPFVPVHARIAAHAQARPDARGVADIERALTRR
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHH
EVDARAARLARHLVAAGVRPEMRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHH
AQIVGDANIAHVLTDGASAASLPELPDLRVWRADEVDALDEAAHVVLPDVLPGHAAYAIY
HHHHCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHEEECCCCCCCEEEEEE
TSGSTGKPKGVIVDHASFALHCAAIAERYGAGESDVFLLFQSVNFDGAHEGWFSQYMSGA
ECCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHCCC
AVSVTADVLWPPAQTCAMMVRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEAT
EEEEEEEECCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCHHEEEECCCCC
SREAFAMLRRALPNVRVVNGYGPTETVITPTLWMFRPGDDLAKLGDAAYLPIGTLVGART
HHHHHHHHHHHCCCCEEEECCCCCCCEECCEEEEECCCHHHHHHCCCCCCCHHHHHHHHH
AHVLDERLHPLPVGVIGELYLGGEGIGVARGYLDRPALTAERFVPDPYGAPGARLYRTGD
HHHHHHHCCCCCCCHHEEEEECCCCCCHHHCCCCCCCCCHHHCCCCCCCCCCCEEEECHH
LVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHEAVREACAVVHGQGALAQLVA
HHHHHHHHHHHHHHCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
YVELTADAQAAAQPVEAATLDAHLRRTLPDYMVPAQLIVLDALPRNANSKVDRARLPAPV
HHHHCCCHHHHHCCHHHHHHHHHHHHCCHHHHCCHHHEEEECCCCCCCCCCHHHCCCCCE
RVERAYEAPHDGDEAALAAIWCDVLNLERVGRGDHFFDLGGHSLAAVRVATRVAERLGRD
EEHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCC
VPVRALFEAPVLAQYALQVADAPRAAHAGAAAPGVAVAKPDAHGVWPLSPAQLGLWFLWR
CCHHHHHHCHHHHHHHHHHHCCCCHHCCCCCCCCCEEECCCCCCCCCCCHHHCCEEEEEE
AQPDSAAYNIPVALRVRGPLDVDALRAAFTDAAAVHPALRARLVARDGVLPGQRIDAAMQ
CCCCCCEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCEEE
VELPVVDLAMQPDALARAAALTDEDALTPFDLAADAPLWRARVLRLDAEDHVLSVTIHHI
EECCEEEEECCCHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHEEEECCCCCEEEEEEEHH
VSDGESIELWLDAVRARYVARVQGNAVPAAAIAQPVVPLVLPAPSHPARVAYWRDALADL
HCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHC
PARVLPQRADAPAVPQWRAARIAFEFDGALIRAARDTASAAHATLPMLLHAALNTALFRT
CHHHCCCCCCCCCCCCCCCEEEEEEECCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHEE
TGASDQPVGVLASTRELTGDAARDALGLFINSVVVRTQLDPAARRTDVLAQVRDMALMAY
CCCCCCCCEEEECCHHHCCHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHH
AHADVPFADVVAALRAPRAAQANPLFQVMFNYLRPTGAAARDWAGLSLAGFDDVRHRVVF
HCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCHHHCCEEEEE
TLELDVVEHPDGRVSAAFSYADELLDRGFVDALVDVYHDEVARFAGASEAALGAPDKHAI
EEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
AQASQRAQAEGNARAATPSRAPHAAASLAALWSDTFAAAAPEADANLFEAGATSFDVVRF
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHH
VDAASRAGHALTVADLFASPTLAALGARLDAPAETGQEARHAG
HHHHHHCCCEEEHHHHHCCCHHHHHCCCCCCCHHCCCHHHCCC
>Mature Secondary Structure 
TKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTR
CCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHH
LWLHARLIDAPDAYHITERLALTGPLDAHALRLACDALIARHEALRTTFDEAQDGVAQTI
HHHHEEEECCCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAPLRCPWRETDLEAVPDAQRAARAEAVATADEAEPFDLGAAPLVRAHLVRFDATHHWLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHH
LTVHHIVSDGWSSGVMLEELAAFYRAYASDRPVPLAPLPIQYADYALWQRRWLDAGERDR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCH
QLAFWRERLDPQRGVLALPGAAARPARRSARGARHVFSLDARIGVQLRAFAAASGATPFA
HHHHHHHHCCCCCCEEECCCCCCCCHHHHHCCCHHEEEECCCCCEEEEEEECCCCCCHHH
VLLAALDALLARATGDARICVGVPAANRERAEVAGLIGFFVNTLAIDVEVPAHGDFSSLV
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHH
ARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVMAAYGERRALPALGTAAAALL
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHC
PSGTPSAKFDLTLSVEATPDGTFDAVFIYALDLFEADAISRLAARFVTLLADALARPDMP
CCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VGDLDWLPAAEREQLFAWNAPAGATESEPFVPVHARIAAHAQARPDARGVADIERALTRR
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHH
EVDARAARLARHLVAAGVRPEMRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHH
AQIVGDANIAHVLTDGASAASLPELPDLRVWRADEVDALDEAAHVVLPDVLPGHAAYAIY
HHHHCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHEEECCCCCCCEEEEEE
TSGSTGKPKGVIVDHASFALHCAAIAERYGAGESDVFLLFQSVNFDGAHEGWFSQYMSGA
ECCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHCCC
AVSVTADVLWPPAQTCAMMVRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEAT
EEEEEEEECCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCHHEEEECCCCC
SREAFAMLRRALPNVRVVNGYGPTETVITPTLWMFRPGDDLAKLGDAAYLPIGTLVGART
HHHHHHHHHHHCCCCEEEECCCCCCCEECCEEEEECCCHHHHHHCCCCCCCHHHHHHHHH
AHVLDERLHPLPVGVIGELYLGGEGIGVARGYLDRPALTAERFVPDPYGAPGARLYRTGD
HHHHHHHCCCCCCCHHEEEEECCCCCCHHHCCCCCCCCCHHHCCCCCCCCCCCEEEECHH
LVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHEAVREACAVVHGQGALAQLVA
HHHHHHHHHHHHHHCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
YVELTADAQAAAQPVEAATLDAHLRRTLPDYMVPAQLIVLDALPRNANSKVDRARLPAPV
HHHHCCCHHHHHCCHHHHHHHHHHHHCCHHHHCCHHHEEEECCCCCCCCCCHHHCCCCCE
RVERAYEAPHDGDEAALAAIWCDVLNLERVGRGDHFFDLGGHSLAAVRVATRVAERLGRD
EEHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCC
VPVRALFEAPVLAQYALQVADAPRAAHAGAAAPGVAVAKPDAHGVWPLSPAQLGLWFLWR
CCHHHHHHCHHHHHHHHHHHCCCCHHCCCCCCCCCEEECCCCCCCCCCCHHHCCEEEEEE
AQPDSAAYNIPVALRVRGPLDVDALRAAFTDAAAVHPALRARLVARDGVLPGQRIDAAMQ
CCCCCCEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCEEE
VELPVVDLAMQPDALARAAALTDEDALTPFDLAADAPLWRARVLRLDAEDHVLSVTIHHI
EECCEEEEECCCHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHEEEECCCCCEEEEEEEHH
VSDGESIELWLDAVRARYVARVQGNAVPAAAIAQPVVPLVLPAPSHPARVAYWRDALADL
HCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHC
PARVLPQRADAPAVPQWRAARIAFEFDGALIRAARDTASAAHATLPMLLHAALNTALFRT
CHHHCCCCCCCCCCCCCCCEEEEEEECCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHEE
TGASDQPVGVLASTRELTGDAARDALGLFINSVVVRTQLDPAARRTDVLAQVRDMALMAY
CCCCCCCCEEEECCHHHCCHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHH
AHADVPFADVVAALRAPRAAQANPLFQVMFNYLRPTGAAARDWAGLSLAGFDDVRHRVVF
HCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCHHHCCEEEEE
TLELDVVEHPDGRVSAAFSYADELLDRGFVDALVDVYHDEVARFAGASEAALGAPDKHAI
EEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
AQASQRAQAEGNARAATPSRAPHAAASLAALWSDTFAAAAPEADANLFEAGATSFDVVRF
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHH
VDAASRAGHALTVADLFASPTLAALGARLDAPAETGQEARHAG
HHHHHHCCCEEEHHHHHCCCHHHHHCCCCCCCHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA