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The map label for this gene is rnr [H]

Identifier: 78066158

GI number: 78066158

Start: 1683390

End: 1685876

Strand: Direct

Name: rnr [H]

Synonym: Bcep18194_A4688

Alternate gene names: 78066158

Gene position: 1683390-1685876 (Clockwise)

Preceding gene: 78066157

Following gene: 78066159

Centisome position: 45.57

GC content: 66.99

Gene sequence:

>2487_bases
TTGAGCAAATATCCGTACCCCATTCCGAGCCGTGAAGAAATTCTCGGCGTGCTGCGTACGAGCGACGCGCCGCTGGCCGC
CAACGACATCGCCGAAGCACTGTCGATCAAGCGTCAGGAGCGCGAGGGGTTCTTCCGGCGTGTCGCCGCGATGGAACGCG
ACGGCCAGATCCGCCTCGACAAGCGCGGCCATTACCAGTTGACCCATCCGTCGAACTTCGTCGCCGGGCGCGTGCAGGGG
CATCGCGACGGCTACGGGTTCGTGATCCGCGACGACGGCCAGGACGACCTGTTTTTGCCGAACGGCGAAATGCAGAAGGT
GATGCACAACGATCGCGTGCTCGCACGGATCGTCGGCTACGATCGTCGCGGCCGCCCGGAAGGGCACGTCGTCGAAGTCA
CCGAGCGCGCGAACAAGCGCGTGATCGGCCGCCTGCTCAACGAGAACGGCGCGCTGATCGTCGCACCGGAAGACAAGCGC
ATCGGCCATGACATCCTGATCACGCAGAACGTGAAGAAGGCGAAGGTCGGGCAGGTCGTCGTTGTCGAGCTGACCGATTT
CCCGAGCCGCCATTCGCAGCCGCTCGGCCGTGTCGTCGAGGTGCTCGGCGACATCGACGATCCGGGCATGGAAATCGAAA
TCGCGGTGCGCAAGTACGGCGTGCCGCACGAATTCAGCCAGCCGGCGCTCGACGAAGCCGCCGCGCTGCCCGACAAGGTG
CGGCCGACCGACCTGCGTTTCCGCGTCGACCTGCGCGACGTGCCGCTCGTGACGATCGACGGCGAGGACGCCCGCGACTT
CGACGACGCCGTCTACTGCGAGCCGGTCAAGGTCGGCCGCGGCGACGGCTACCGCCTGATCGTCGCGATCGCCGACGTGT
CGCACTACGTACAGCCGGGCAGCGGGCTCGATGCCGACGCGCTCGAGCGCAGCACGTCGGTCTACTTCCCGCGCCGTGTG
ATTCCGATGCTGCCGGAGAAGCTGTCGAACGGCCTGTGCTCGCTGAATCCGCAGGTCGACCGCTGCGTGCTCGCGTGCGA
CATGGTGATCACCGCGCGCGGCGAGATCAAGGCGTACCAGTTTTATCCGGCCGTCATCCATTCGGCTGCGCGCCTCACGT
ACACCGAAGTCGCGGCCGTGCTGTCGAACACGAAGGGGCCGGAGGCGGCGCGCCGCGCGGATATTCTGCCGCACCTGCAG
GATCTGTACGGCGTCTACAAGTCGCTGTTCGCCGCGCGGCAGAAGCGCGGCGCGATCGACTTCGACACGACCGAGACCTA
CATCGTCTGCAACTCGCAGGGCAAGATCGAGCAGATCGTGCCGCGCCAGCGTAACGACGCGCACAAGCTGATCGAGGAAT
GCATGCTGGCCGCGAACGTCTGCGCGGCCGATTTCCTGAAGCGCAACAAGCATCCGGGCCTGTACCGCGTGCACGCGGGG
CCGACGCCGGAGAAGCTCGAGAACCTGCGCGCGTTCCTGCGCGGCATGGGCCTTTCGCTCGGTGGCGGCGACAAGCCGCA
TGCGAGCGACTACGCGGCGCTGATGGCGCAGATCCGCGACCGGCCCGATGCGCAGATGCTGCAGCCGATGTTGCTGCGCT
CGATGCAGCAGGCCGTCTACAGCCCGGACAACATCGGTCACTTCGGCCTGGCCTACGAGGCATACGCGCACTTCACGAGC
CCGATCCGCCGTTATCCGGACTTGCTCACGCACCGCGCGATCTACGCGATCCTGTCCGGCAAGAAGTACACGCCGAAGGC
GCCGGACGGTTTCGAGCTGAACACCGCGCTGTCGCCGCGCGCCCGCGCGATGCAGCAGGCCGACGACGAATCGCGCGGCC
GCTCGCGCTCGAACACGGCGATCTGGGAAGAACTCGGCCTGCACTGCTCGGCGAACGAGCGCCGCGCGGATGAAGCATCG
CGCGACGTCGAAGCCTGGCTCAAGTGCTACTTCATGCGCGACAAGCTCGGCGAGGAGTACGGCGGGATGGTGAACGGCGT
CACGTCGTTCGGCATCTTCGTGCAGCTCGACACGCTCTTCATCGAAGGGCTCGTGCACGTCACGGAACTCGGCTCGGACT
ACTTCCAGTACGACGAGATCAAGAACGAGCTGCGTGGCGAACGCACGGGCATCCGTTATCGCCTGTCGGATCGCGTGCGC
GTGCAGGTGAGCCGCGTCGATCTCGATGCACGCAAGATCGATTTCCGGCTCGTGCGCGATACGCCGGTGAAGGCGCCGCG
TCCGTCGCCCGTGCCGGCTTCCGCGGGTGGCGGTGTCGACCGCGGCAATGGTCCGCGCGTACGCGCACTGCCGCAGGCGG
AGGAGCCCGCGCCGCGCCGCAAGAAGGCCGCAAGCGCGCCGAGCGTCGCGGTGAATGAAGCGCGCGCCGCGCGTGCCGCC
GCGAAGAAGAAGGGCGGCAGCGGCAGCGGTGGCGGTGCGGCGGCGAAGCCGACCGCGAAGAAGACACGCGCCCGCAAGAA
GTATTGA

Upstream 100 bases:

>100_bases
AATGACCCGCCGCCGTCAATATAGAACTGTCTGAAGGACACCTCTATGTTGATGCCGTGCACCATCAATCAACGCAACGA
GAACAACCATCGACAAACCC

Downstream 100 bases:

>100_bases
GCGTTCGGGGCGGCGCCAGCGACCGCCCTGCAGTATCGAGAGACGCCGCGTCACCGGCCATCAGCCGGCAACGCGGCGCT
TTCCTTTTCCATGGATCGCG

Product: 3'-5' exoribonuclease, VacB and RNase II/ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 828; Mature: 827

Protein sequence:

>828_residues
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQG
HRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKR
IGHDILITQNVKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQPALDEAAALPDKV
RPTDLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPVKVGRGDGYRLIVAIADVSHYVQPGSGLDADALERSTSVYFPRRV
IPMLPEKLSNGLCSLNPQVDRCVLACDMVITARGEIKAYQFYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADILPHLQ
DLYGVYKSLFAARQKRGAIDFDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHPGLYRVHAG
PTPEKLENLRAFLRGMGLSLGGGDKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYEAYAHFTS
PIRRYPDLLTHRAIYAILSGKKYTPKAPDGFELNTALSPRARAMQQADDESRGRSRSNTAIWEELGLHCSANERRADEAS
RDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVSRVDLDARKIDFRLVRDTPVKAPRPSPVPASAGGGVDRGNGPRVRALPQAEEPAPRRKKAASAPSVAVNEARAARAA
AKKKGGSGSGGGAAAKPTAKKTRARKKY

Sequences:

>Translated_828_residues
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQG
HRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKR
IGHDILITQNVKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQPALDEAAALPDKV
RPTDLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPVKVGRGDGYRLIVAIADVSHYVQPGSGLDADALERSTSVYFPRRV
IPMLPEKLSNGLCSLNPQVDRCVLACDMVITARGEIKAYQFYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADILPHLQ
DLYGVYKSLFAARQKRGAIDFDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHPGLYRVHAG
PTPEKLENLRAFLRGMGLSLGGGDKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYEAYAHFTS
PIRRYPDLLTHRAIYAILSGKKYTPKAPDGFELNTALSPRARAMQQADDESRGRSRSNTAIWEELGLHCSANERRADEAS
RDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVSRVDLDARKIDFRLVRDTPVKAPRPSPVPASAGGGVDRGNGPRVRALPQAEEPAPRRKKAASAPSVAVNEARAARAA
AKKKGGSGSGGGAAAKPTAKKTRARKKY
>Mature_827_residues
SKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQGH
RDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKRI
GHDILITQNVKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQPALDEAAALPDKVR
PTDLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPVKVGRGDGYRLIVAIADVSHYVQPGSGLDADALERSTSVYFPRRVI
PMLPEKLSNGLCSLNPQVDRCVLACDMVITARGEIKAYQFYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADILPHLQD
LYGVYKSLFAARQKRGAIDFDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHPGLYRVHAGP
TPEKLENLRAFLRGMGLSLGGGDKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYEAYAHFTSP
IRRYPDLLTHRAIYAILSGKKYTPKAPDGFELNTALSPRARAMQQADDESRGRSRSNTAIWEELGLHCSANERRADEASR
DVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVRV
QVSRVDLDARKIDFRLVRDTPVKAPRPSPVPASAGGGVDRGNGPRVRALPQAEEPAPRRKKAASAPSVAVNEARAARAAA
KKKGGSGSGGGAAAKPTAKKTRARKKY

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=487, Percent_Identity=29.5687885010267, Blast_Score=199, Evalue=8e-51,
Organism=Homo sapiens, GI190014623, Length=487, Percent_Identity=29.5687885010267, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI134288890, Length=440, Percent_Identity=30.9090909090909, Blast_Score=174, Evalue=3e-43,
Organism=Homo sapiens, GI19115966, Length=657, Percent_Identity=25.8751902587519, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI219521928, Length=657, Percent_Identity=25.8751902587519, Blast_Score=159, Evalue=1e-38,
Organism=Escherichia coli, GI87082383, Length=749, Percent_Identity=48.5981308411215, Blast_Score=691, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=693, Percent_Identity=26.984126984127, Blast_Score=201, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI212645896, Length=416, Percent_Identity=30.7692307692308, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17553506, Length=528, Percent_Identity=28.9772727272727, Blast_Score=166, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6324552, Length=657, Percent_Identity=25.5707762557078, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24649634, Length=468, Percent_Identity=28.8461538461538, Blast_Score=184, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24654592, Length=435, Percent_Identity=29.4252873563218, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI19922976, Length=435, Percent_Identity=29.4252873563218, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24654597, Length=435, Percent_Identity=29.4252873563218, Blast_Score=147, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 91870; Mature: 91738

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLD
CCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
KRGHYQLTHPSNFVAGRVQGHRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGY
CCCCEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEECCCCHHHHHHHCCHHHHHHHCC
DRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKRIGHDILITQNVKKAKVGQVV
CCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCHHCCCCEE
VVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQPALDEAAALPDKV
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCC
RPTDLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPVKVGRGDGYRLIVAIADVSHYVQPG
CCCCEEEEEEECCCCEEEECCCCCCCCCCCEEECEEEECCCCCCEEEEEEECHHHHCCCC
SGLDADALERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLACDMVITARGEIKAYQ
CCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHEEEECCCCEEEEE
FYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADILPHLQDLYGVYKSLFAARQKRGAID
EEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHPGLYRVHAG
CCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
PTPEKLENLRAFLRGMGLSLGGGDKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVY
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
SPDNIGHFGLAYEAYAHFTSPIRRYPDLLTHRAIYAILSGKKYTPKAPDGFELNTALSPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCHH
ARAMQQADDESRGRSRSNTAIWEELGLHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
HHHHHHCCHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
GGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
CCHHHCHHHHEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
VQVSRVDLDARKIDFRLVRDTPVKAPRPSPVPASAGGGVDRGNGPRVRALPQAEEPAPRR
EEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHH
KKAASAPSVAVNEARAARAAAKKKGGSGSGGGAAAKPTAKKTRARKKY
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
SKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLD
CCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
KRGHYQLTHPSNFVAGRVQGHRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGY
CCCCEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEECCCCHHHHHHHCCHHHHHHHCC
DRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKRIGHDILITQNVKKAKVGQVV
CCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCHHCCCCEE
VVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQPALDEAAALPDKV
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCC
RPTDLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPVKVGRGDGYRLIVAIADVSHYVQPG
CCCCEEEEEEECCCCEEEECCCCCCCCCCCEEECEEEECCCCCCEEEEEEECHHHHCCCC
SGLDADALERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLACDMVITARGEIKAYQ
CCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHEEEECCCCEEEEE
FYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADILPHLQDLYGVYKSLFAARQKRGAID
EEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHPGLYRVHAG
CCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
PTPEKLENLRAFLRGMGLSLGGGDKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVY
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
SPDNIGHFGLAYEAYAHFTSPIRRYPDLLTHRAIYAILSGKKYTPKAPDGFELNTALSPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCHH
ARAMQQADDESRGRSRSNTAIWEELGLHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
HHHHHHCCHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
GGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
CCHHHCHHHHEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
VQVSRVDLDARKIDFRLVRDTPVKAPRPSPVPASAGGGVDRGNGPRVRALPQAEEPAPRR
EEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHH
KKAASAPSVAVNEARAARAAAKKKGGSGSGGGAAAKPTAKKTRARKKY
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]