Click here to switch to the map view.

The map label for this gene is yhcS [C]

Identifier: 78066066

GI number: 78066066

Start: 1577255

End: 1578196

Strand: Direct

Name: yhcS [C]

Synonym: Bcep18194_A4595

Alternate gene names: 78066066

Gene position: 1577255-1578196 (Clockwise)

Preceding gene: 78066061

Following gene: 78066072

Centisome position: 42.7

GC content: 67.94

Gene sequence:

>942_bases
ATGGATACGTTACAAAACATGCGGGTATTCGTCCGCGTGGTTGACGCGGGAAGCTTTACCGCGGCGGCCCAGCAGATGAA
TTCGACTACCGCCTACGCGTCGCGCGCGGTCTCGGATCTCGAGGCGCACCTGCGCACGCGCCTCCTGAACCGCACGACGC
GCCGGATCGCGCTGACCGAAGCCGGCGAGCGCTACCTGCAGCGCTGCGAGCAGATCCTCGCGTATGTCGACCAGGCCGAA
GCCGAGGCGGGCGACGCGCATGCGCGCCCGTCGGGCAAGCTGAAGGTGCATTGCTTCACGAGCCTCGGCCAGCACTACCT
GGTGCCGGCCATCGCGCGCTATCGCGAGCGCTACCCGGACGTGCACGTCGAGCTGACGCTCGCGCAGCGGATGCCCGACC
TGCTCGACGAGGGGTATGACGTCGCGATCGTCGTCGGCCGCGACCTGCCCGATTCGGGGCTCGTGTCGCAGCGGCTCGGC
GAGAGCTACAGCGTGGTGTGCGCGTCGCGCAACTATGTCGAGGCGCACGGCGTGCCGCAGCGGCCGGCCGATCTCGCGCA
GCACGTCTGCCTCGGGATGGTCGCGCCGGGCTTCCAGTTCGACGAATGGGCGCTGGCGGGTCCGAACGGCGACGAAGTCG
TCCCGATCACGGCGCCACCGTTTCGCGTGAACGTCGCCGAGGCGCTTGCTGTCGCGGTGCGGGAAGGGATGGGGATCGGC
GGTCTGCCGCTTTATTCGGCGATCGGCTGGTTGCGCAGCGGGCACATCGTGCGCGTGATGCCCGAATACCGGTCGCACGT
GATGAACATCTACGCGCTGTATCCGTCGCGCCAGTACCTCGACGCGAAAATTCGCACCTGGGTCGATTTCCTGCGCGACG
AACTGCCGGCCACGCTCGCCGCCGACGAAGCCGCGCTCGAGCAGTACACGCGTGCGACATGA

Upstream 100 bases:

>100_bases
CTGAATAAATGGACAAGGGTGCAAGTCATTTTTACGAATCCTGAGACAATACTTGTTCGCCTCTGTGCAACAATCCGTCC
GGATTCAAACGGGTAATGGG

Downstream 100 bases:

>100_bases
CAGCGCGGTTGACCGCAATCTGACGAGATTTGTCCTTCACGCAACATTTTTTTACGAACGCGTGTCAGACAGTTTGATAC
TGTGGGAATTAACGAGATAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVDQAE
AEAGDAHARPSGKLKVHCFTSLGQHYLVPAIARYRERYPDVHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLG
ESYSVVCASRNYVEAHGVPQRPADLAQHVCLGMVAPGFQFDEWALAGPNGDEVVPITAPPFRVNVAEALAVAVREGMGIG
GLPLYSAIGWLRSGHIVRVMPEYRSHVMNIYALYPSRQYLDAKIRTWVDFLRDELPATLAADEAALEQYTRAT

Sequences:

>Translated_313_residues
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVDQAE
AEAGDAHARPSGKLKVHCFTSLGQHYLVPAIARYRERYPDVHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLG
ESYSVVCASRNYVEAHGVPQRPADLAQHVCLGMVAPGFQFDEWALAGPNGDEVVPITAPPFRVNVAEALAVAVREGMGIG
GLPLYSAIGWLRSGHIVRVMPEYRSHVMNIYALYPSRQYLDAKIRTWVDFLRDELPATLAADEAALEQYTRAT
>Mature_313_residues
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVDQAE
AEAGDAHARPSGKLKVHCFTSLGQHYLVPAIARYRERYPDVHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLG
ESYSVVCASRNYVEAHGVPQRPADLAQHVCLGMVAPGFQFDEWALAGPNGDEVVPITAPPFRVNVAEALAVAVREGMGIG
GLPLYSAIGWLRSGHIVRVMPEYRSHVMNIYALYPSRQYLDAKIRTWVDFLRDELPATLAADEAALEQYTRAT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=36.3945578231293, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=35.2739726027397, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=31.8339100346021, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=29.2682926829268, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=29.96632996633, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=26.7123287671233, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=24.5733788395904, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789173, Length=189, Percent_Identity=30.6878306878307, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI145693105, Length=122, Percent_Identity=29.5081967213115, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787879, Length=154, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=24.7457627118644, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788748, Length=123, Percent_Identity=32.520325203252, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786448, Length=294, Percent_Identity=21.7687074829932, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34672; Mature: 34672

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTE
CCCHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGERYLQRCEQILAYVDQAEAEAGDAHARPSGKLKVHCFTSLGQHYLVPAIARYRERYPD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHCCC
VHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLGESYSVVCASRNYVEAHGVPQ
EEEEEEHHHHCHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCC
RPADLAQHVCLGMVAPGFQFDEWALAGPNGDEVVPITAPPFRVNVAEALAVAVREGMGIG
CHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEECCCCCEECHHHHHHHHHHHCCCCC
GLPLYSAIGWLRSGHIVRVMPEYRSHVMNIYALYPSRQYLDAKIRTWVDFLRDELPATLA
CHHHHHHHHHHHCCCEEEECHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHH
ADEAALEQYTRAT
HHHHHHHHHHCCC
>Mature Secondary Structure
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTE
CCCHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGERYLQRCEQILAYVDQAEAEAGDAHARPSGKLKVHCFTSLGQHYLVPAIARYRERYPD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHCCC
VHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLGESYSVVCASRNYVEAHGVPQ
EEEEEEHHHHCHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCC
RPADLAQHVCLGMVAPGFQFDEWALAGPNGDEVVPITAPPFRVNVAEALAVAVREGMGIG
CHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEECCCCCEECHHHHHHHHHHHCCCCC
GLPLYSAIGWLRSGHIVRVMPEYRSHVMNIYALYPSRQYLDAKIRTWVDFLRDELPATLA
CHHHHHHHHHHHCCCEEEECHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHH
ADEAALEQYTRAT
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]