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The map label for this gene is glnS [H]

Identifier: 78066020

GI number: 78066020

Start: 1520297

End: 1522006

Strand: Reverse

Name: glnS [H]

Synonym: Bcep18194_A4549

Alternate gene names: 78066020

Gene position: 1522006-1520297 (Counterclockwise)

Preceding gene: 78066023

Following gene: 78066016

Centisome position: 41.2

GC content: 63.98

Gene sequence:

>1710_bases
ATGAGCACCGAACGCAACGACGCCCCCGCGGCTTCCAATTTCATCCGCAACATCATCGACGACGACAACCGCACCGGCAA
ATGGAGCGGCCGCGTCGAGACGCGCTTTCCGCCCGAGCCGAACGGCTATCTGCACATCGGGCACGCCAAGAGCATCTGCC
TGAACTTCAGCGTCGCGCGCGACTACGGTGGCGTGTGCCACCTGCGCTTCGACGATACGAACCCGGAAAAGGAAAGCGTC
GAATACGTCGATTCGATCGTCGACGCGGTGCGCTGGCTCGGCTTCGACTGGCGCAAGGATGCGGTCGATCACCAGTACTT
CGCGAGCGACTACTACGACAAGCTGTACGAGTTCGCCGAACTTCTGATCCAGCGCGGCAAGGCGTATGTCGACAGCCAGA
GCGCCGATGAAATGCGCGCGAACCGCGGCTCGCTGACGGAAGGCGGCAAGCCGTCGCCGTTCCGCGAGCGCACGCCGGAA
GAAAACCTCGACCTGTTCCGCCGCATGAAGGCCGGCGAGTTCAAGGAAGGCGAGCACGTGCTGCGCGCGAAGATCGACAT
GGCTTCGCCGAACATGAACATGCGCGACCCGGTGATCTACCGGATCCGCTACGCGCACCACTACCGCACCGGCGACGCAT
GGTGCGTGTACCCGATGTACGACTACACGCACTGCATCTCGGATGCGCTCGAAGGCATCACGCATTCGCTGTGCACGCTC
GAATTCGAGGATCACCGACCGCTGTACGACTGGGTGCTGAACGAACTCGCGGAAGCCGGCATGTTCACGCGCCCGCTGCC
GCAACAGATCGAATTCTCGCGACTGAACCTCACGTACGCGATCACCAGCAAGCGCAAGCTGCTGCAGCTCGTGACCGAAG
GCCACGTCGACGGCTGGGACGACCCGCGGATGCCGACGATCGTCGGCGTGCGCCGCCGCGGCTTCACGCCGGAGAGCATC
CACCTGTTCTGCGAGCGGATCGGCGTGACGAAGATCGACTCGTGGATCGACATGAGCATCTTCGAAGGCGCGCTGCGCGA
CGACCTCGACGACAAGGCCGCACGCACGGTCGCCGTGCTCGATCCGCTGAAGCTCGTGATCGACAACTACCCGGAAGACC
TCGAAGAAGCGTGCACGGCGCCCGTGCACCCGCACCACCCGGACCGCGGCGTGCGCACGTTCCCGATCTCGCGCGAGCTG
TGGATCGAGCGCGAGGACTTCGTCGAGAACCCGCCGAAGGGCTATTTCCGCCTGTTCCCGGGCAACAAGGTGCGCCTGCG
CTACGGCTACGTGATCGAGTGCACGGGCTTCGACAAGGACGCCGACGGCAACGTGACGGCCGTGCACTGCAACTACTTCC
CGGACAGCAAGTCGGGTACCGAAGGCGCGAACACGTACAAGGTCAAGGGCAACATCCACTGGGTCAGCGCGAAGCATGCG
CAACCGGCCGAAGTGCGGATCTACGACCGCCTGTTCAAGGAGCCGCATCCGGACGCGGGCGGCGCGAACTTCCTCGAAGC
GCTGAATCCCGATTCGAAGAAGATCGTGCAGGCATATATCGAACCGGGCAACGACGACATCGCGCCGGAAACGCGCCTGC
AGTTCGAGCGTCACGGCTACTTCGTGGCGGATCGCGTCGATTCGAAGCCGGGCAAGCCGGTGTTCAACCGGATCGTCGGG
CTGCGCGACAGCTGGGGCAAGCCGGCGTAA

Upstream 100 bases:

>100_bases
CCCGCCATGCTGCAAGCCGCGCGGGACGGACCCCGGTCAGGTAGAATCACGGGATTAAACCGGCGCGACGCGCGCGCCGA
CACAACCTGACGCCATCCGC

Downstream 100 bases:

>100_bases
CGGCGTGCTTCACGCGCGGCGGTGTGCGGCTTCGAAAGCCACCGTCGCGTGACCATGAAAAAACCGGCCCCAGGGCCGGT
TTTTTGTTGCGTGCCATGAA

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSTERNDAPAASNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVARDYGGVCHLRFDDTNPEKESV
EYVDSIVDAVRWLGFDWRKDAVDHQYFASDYYDKLYEFAELLIQRGKAYVDSQSADEMRANRGSLTEGGKPSPFRERTPE
ENLDLFRRMKAGEFKEGEHVLRAKIDMASPNMNMRDPVIYRIRYAHHYRTGDAWCVYPMYDYTHCISDALEGITHSLCTL
EFEDHRPLYDWVLNELAEAGMFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDGWDDPRMPTIVGVRRRGFTPESI
HLFCERIGVTKIDSWIDMSIFEGALRDDLDDKAARTVAVLDPLKLVIDNYPEDLEEACTAPVHPHHPDRGVRTFPISREL
WIEREDFVENPPKGYFRLFPGNKVRLRYGYVIECTGFDKDADGNVTAVHCNYFPDSKSGTEGANTYKVKGNIHWVSAKHA
QPAEVRIYDRLFKEPHPDAGGANFLEALNPDSKKIVQAYIEPGNDDIAPETRLQFERHGYFVADRVDSKPGKPVFNRIVG
LRDSWGKPA

Sequences:

>Translated_569_residues
MSTERNDAPAASNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVARDYGGVCHLRFDDTNPEKESV
EYVDSIVDAVRWLGFDWRKDAVDHQYFASDYYDKLYEFAELLIQRGKAYVDSQSADEMRANRGSLTEGGKPSPFRERTPE
ENLDLFRRMKAGEFKEGEHVLRAKIDMASPNMNMRDPVIYRIRYAHHYRTGDAWCVYPMYDYTHCISDALEGITHSLCTL
EFEDHRPLYDWVLNELAEAGMFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDGWDDPRMPTIVGVRRRGFTPESI
HLFCERIGVTKIDSWIDMSIFEGALRDDLDDKAARTVAVLDPLKLVIDNYPEDLEEACTAPVHPHHPDRGVRTFPISREL
WIEREDFVENPPKGYFRLFPGNKVRLRYGYVIECTGFDKDADGNVTAVHCNYFPDSKSGTEGANTYKVKGNIHWVSAKHA
QPAEVRIYDRLFKEPHPDAGGANFLEALNPDSKKIVQAYIEPGNDDIAPETRLQFERHGYFVADRVDSKPGKPVFNRIVG
LRDSWGKPA
>Mature_568_residues
STERNDAPAASNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVARDYGGVCHLRFDDTNPEKESVE
YVDSIVDAVRWLGFDWRKDAVDHQYFASDYYDKLYEFAELLIQRGKAYVDSQSADEMRANRGSLTEGGKPSPFRERTPEE
NLDLFRRMKAGEFKEGEHVLRAKIDMASPNMNMRDPVIYRIRYAHHYRTGDAWCVYPMYDYTHCISDALEGITHSLCTLE
FEDHRPLYDWVLNELAEAGMFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDGWDDPRMPTIVGVRRRGFTPESIH
LFCERIGVTKIDSWIDMSIFEGALRDDLDDKAARTVAVLDPLKLVIDNYPEDLEEACTAPVHPHHPDRGVRTFPISRELW
IEREDFVENPPKGYFRLFPGNKVRLRYGYVIECTGFDKDADGNVTAVHCNYFPDSKSGTEGANTYKVKGNIHWVSAKHAQ
PAEVRIYDRLFKEPHPDAGGANFLEALNPDSKKIVQAYIEPGNDDIAPETRLQFERHGYFVADRVDSKPGKPVFNRIVGL
RDSWGKPA

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=547, Percent_Identity=44.7897623400366, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI62241042, Length=532, Percent_Identity=34.7744360902256, Blast_Score=264, Evalue=2e-70,
Organism=Escherichia coli, GI1786895, Length=557, Percent_Identity=56.5529622980251, Blast_Score=630, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=122, Percent_Identity=30.327868852459, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17543332, Length=544, Percent_Identity=43.3823529411765, Blast_Score=396, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17511007, Length=529, Percent_Identity=30.6238185255198, Blast_Score=227, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6324742, Length=578, Percent_Identity=41.522491349481, Blast_Score=410, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6321192, Length=531, Percent_Identity=33.5216572504708, Blast_Score=254, Evalue=3e-68,
Organism=Drosophila melanogaster, GI17864488, Length=553, Percent_Identity=42.49547920434, Blast_Score=409, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24649466, Length=423, Percent_Identity=36.6430260047281, Blast_Score=236, Evalue=4e-62,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 65280; Mature: 65149

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTERNDAPAASNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVAR
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCEEEECCCCEEEEEEEEEC
DYGGVCHLRFDDTNPEKESVEYVDSIVDAVRWLGFDWRKDAVDHQYFASDYYDKLYEFAE
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHH
LLIQRGKAYVDSQSADEMRANRGSLTEGGKPSPFRERTPEENLDLFRRMKAGEFKEGEHV
HHHHCCCHHCCCCCHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCEE
LRAKIDMASPNMNMRDPVIYRIRYAHHYRTGDAWCVYPMYDYTHCISDALEGITHSLCTL
EEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEE
EFEDHRPLYDWVLNELAEAGMFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDGWD
EECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCCCCCCC
DPRMPTIVGVRRRGFTPESIHLFCERIGVTKIDSWIDMSIFEGALRDDLDDKAARTVAVL
CCCCCCEEEHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHEEHHH
DPLKLVIDNYPEDLEEACTAPVHPHHPDRGVRTFPISRELWIEREDFVENPPKGYFRLFP
HHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCEECCCCHHHCCCCHHHHCCCCCCEEEECC
GNKVRLRYGYVIECTGFDKDADGNVTAVHCNYFPDSKSGTEGANTYKVKGNIHWVSAKHA
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEECEEEEEECCCC
QPAEVRIYDRLFKEPHPDAGGANFLEALNPDSKKIVQAYIEPGNDDIAPETRLQFERHGY
CCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCE
FVADRVDSKPGKPVFNRIVGLRDSWGKPA
EEEECCCCCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
STERNDAPAASNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVAR
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCEEEECCCCEEEEEEEEEC
DYGGVCHLRFDDTNPEKESVEYVDSIVDAVRWLGFDWRKDAVDHQYFASDYYDKLYEFAE
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHH
LLIQRGKAYVDSQSADEMRANRGSLTEGGKPSPFRERTPEENLDLFRRMKAGEFKEGEHV
HHHHCCCHHCCCCCHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCEE
LRAKIDMASPNMNMRDPVIYRIRYAHHYRTGDAWCVYPMYDYTHCISDALEGITHSLCTL
EEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEE
EFEDHRPLYDWVLNELAEAGMFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDGWD
EECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCCCCCCC
DPRMPTIVGVRRRGFTPESIHLFCERIGVTKIDSWIDMSIFEGALRDDLDDKAARTVAVL
CCCCCCEEEHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHEEHHH
DPLKLVIDNYPEDLEEACTAPVHPHHPDRGVRTFPISRELWIEREDFVENPPKGYFRLFP
HHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCEECCCCHHHCCCCHHHHCCCCCCEEEECC
GNKVRLRYGYVIECTGFDKDADGNVTAVHCNYFPDSKSGTEGANTYKVKGNIHWVSAKHA
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEECEEEEEECCCC
QPAEVRIYDRLFKEPHPDAGGANFLEALNPDSKKIVQAYIEPGNDDIAPETRLQFERHGY
CCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCE
FVADRVDSKPGKPVFNRIVGLRDSWGKPA
EEEECCCCCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA