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The map label for this gene is ywbI [H]

Identifier: 78065939

GI number: 78065939

Start: 1429507

End: 1430454

Strand: Reverse

Name: ywbI [H]

Synonym: Bcep18194_A4468

Alternate gene names: 78065939

Gene position: 1430454-1429507 (Counterclockwise)

Preceding gene: 78065946

Following gene: 78065938

Centisome position: 38.72

GC content: 64.03

Gene sequence:

>948_bases
ATGAACGTGCGTTTTCTCGAGACCTTCGTCTGGTTGGCCCGTCTGCGCAACTTCCGCCTGACCGCCGAACGCATGCACGC
GACCCAGGCGGCGATATCGAGCCGCATTTCCGCACTCGAACAGGAAATGGGCGTGCGGCTGTTCGACCGCGGGCCGCGTG
AAGTCACGCTGACCCAGGTCGGCACGAAAGCGCTCCCCTTCGCGGAACAGATACTCAAGCTGAACCAGCTGATGCTCGAC
AGCGTCGGCGACCGCTCGAAGATTTCCGGATTGCTGAGGCTCGGCGCCGTGGAATCGATCATTCACACGTGGCTGCCCGA
ACTCCTGAAGCGCGTACGCGACGAATATCCGAATCTCACCATCGAACTGACCGGCGACACCTCGTCGCATCTCGTTGCCC
AGCTGGCCAGCGGCCACATCGACGTGGCACTGCAGACCACCGTGACGACCGGCACGGAGACGTCGAGCATTGCGCTCGGC
AGCTTGCCGATGTGCTGGATCGCCAGCCCGTCCCTCAACATTTCGGACGAGGCGCTGTCGGAAGCGGAGCTCGCCGCCTT
TCCGATCATCGGGTTCGCGCGCCACTCGCTGCCGCATACGTTCCTGGTCGACCTGTTCGAATCGGTCGGCGAGCCGACTG
CCCAGATCAACTGCATGTCGTCGGTCGCCGCCATCATCCACATGGTGATCGACGGCTTCGGCATTGCCGTATTGCCGAGC
GCCTTCGTGATGAAGGAGCTGGCCGATGCCAGGCTGCAGATGCTGAAAGTGACTCACCGCGTGCCGGCCCTGCCGCTGAT
CGCCGCCTACCGGCGCAACCCCGACAGCCTGCTGCCCGAGTCGATCGCCCGGCTCGCGCTCGCCGTCATGCTCGACTTCG
CGCTCGTGAACGGACCGCAATTCGCGCTGCTTCCGGAAACCGTCAGCGCGCCCCCTTCAAACACCTGA

Upstream 100 bases:

>100_bases
CGTCAGGATTTTCCCGAGTCAACCACGAGATTTTTCCGCCATGACGGGCGGCACGCCGCGCTAAACTGCCGCTCAACCTC
GCAACTTTGGGTCACGCGAC

Downstream 100 bases:

>100_bases
TCCCGACGACACCCCTCTGCGCCATGCCGACCATTCCGATTCAACCGCTTACCGCGGACGCCTGCTCTCCGTACGGCACG
ATGCTGGGCAAACCGCCGAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNVRFLETFVWLARLRNFRLTAERMHATQAAISSRISALEQEMGVRLFDRGPREVTLTQVGTKALPFAEQILKLNQLMLD
SVGDRSKISGLLRLGAVESIIHTWLPELLKRVRDEYPNLTIELTGDTSSHLVAQLASGHIDVALQTTVTTGTETSSIALG
SLPMCWIASPSLNISDEALSEAELAAFPIIGFARHSLPHTFLVDLFESVGEPTAQINCMSSVAAIIHMVIDGFGIAVLPS
AFVMKELADARLQMLKVTHRVPALPLIAAYRRNPDSLLPESIARLALAVMLDFALVNGPQFALLPETVSAPPSNT

Sequences:

>Translated_315_residues
MNVRFLETFVWLARLRNFRLTAERMHATQAAISSRISALEQEMGVRLFDRGPREVTLTQVGTKALPFAEQILKLNQLMLD
SVGDRSKISGLLRLGAVESIIHTWLPELLKRVRDEYPNLTIELTGDTSSHLVAQLASGHIDVALQTTVTTGTETSSIALG
SLPMCWIASPSLNISDEALSEAELAAFPIIGFARHSLPHTFLVDLFESVGEPTAQINCMSSVAAIIHMVIDGFGIAVLPS
AFVMKELADARLQMLKVTHRVPALPLIAAYRRNPDSLLPESIARLALAVMLDFALVNGPQFALLPETVSAPPSNT
>Mature_315_residues
MNVRFLETFVWLARLRNFRLTAERMHATQAAISSRISALEQEMGVRLFDRGPREVTLTQVGTKALPFAEQILKLNQLMLD
SVGDRSKISGLLRLGAVESIIHTWLPELLKRVRDEYPNLTIELTGDTSSHLVAQLASGHIDVALQTTVTTGTETSSIALG
SLPMCWIASPSLNISDEALSEAELAAFPIIGFARHSLPHTFLVDLFESVGEPTAQINCMSSVAAIIHMVIDGFGIAVLPS
AFVMKELADARLQMLKVTHRVPALPLIAAYRRNPDSLLPESIARLALAVMLDFALVNGPQFALLPETVSAPPSNT

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=251, Percent_Identity=27.8884462151394, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787128, Length=172, Percent_Identity=31.3953488372093, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788626, Length=169, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI48994962, Length=176, Percent_Identity=31.25, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693105, Length=240, Percent_Identity=22.9166666666667, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=32.4137931034483, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082132, Length=262, Percent_Identity=24.0458015267176, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787879, Length=263, Percent_Identity=26.9961977186312, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788748, Length=256, Percent_Identity=25.390625, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786401, Length=269, Percent_Identity=25.2788104089219, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788887, Length=279, Percent_Identity=24.7311827956989, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788481, Length=235, Percent_Identity=25.531914893617, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787806, Length=272, Percent_Identity=23.1617647058824, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788706, Length=128, Percent_Identity=34.375, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34326; Mature: 34326

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVRFLETFVWLARLRNFRLTAERMHATQAAISSRISALEQEMGVRLFDRGPREVTLTQV
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEECC
GTKALPFAEQILKLNQLMLDSVGDRSKISGLLRLGAVESIIHTWLPELLKRVRDEYPNLT
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
IELTGDTSSHLVAQLASGHIDVALQTTVTTGTETSSIALGSLPMCWIASPSLNISDEALS
EEEECCCHHHHHHHHHCCCEEEEEEEEEECCCCCCCEEECCCCEEEEECCCCCCCHHHHH
EAELAAFPIIGFARHSLPHTFLVDLFESVGEPTAQINCMSSVAAIIHMVIDGFGIAVLPS
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AFVMKELADARLQMLKVTHRVPALPLIAAYRRNPDSLLPESIARLALAVMLDFALVNGPQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHCCCC
FALLPETVSAPPSNT
EEECCCHHCCCCCCC
>Mature Secondary Structure
MNVRFLETFVWLARLRNFRLTAERMHATQAAISSRISALEQEMGVRLFDRGPREVTLTQV
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEECC
GTKALPFAEQILKLNQLMLDSVGDRSKISGLLRLGAVESIIHTWLPELLKRVRDEYPNLT
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
IELTGDTSSHLVAQLASGHIDVALQTTVTTGTETSSIALGSLPMCWIASPSLNISDEALS
EEEECCCHHHHHHHHHCCCEEEEEEEEEECCCCCCCEEECCCCEEEEECCCCCCCHHHHH
EAELAAFPIIGFARHSLPHTFLVDLFESVGEPTAQINCMSSVAAIIHMVIDGFGIAVLPS
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AFVMKELADARLQMLKVTHRVPALPLIAAYRRNPDSLLPESIARLALAVMLDFALVNGPQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHCCCC
FALLPETVSAPPSNT
EEECCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]