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The map label for this gene is ompR [H]

Identifier: 78065828

GI number: 78065828

Start: 1311709

End: 1312467

Strand: Direct

Name: ompR [H]

Synonym: Bcep18194_A4357

Alternate gene names: 78065828

Gene position: 1311709-1312467 (Clockwise)

Preceding gene: 78065820

Following gene: 78065830

Centisome position: 35.51

GC content: 63.37

Gene sequence:

>759_bases
ATGAGTGCGGGGGACATCTCACCGCCGCAACATCGGAGACAAGACGCCGTGAACAAAGCGATTCGTATTCTCGTCGTCGA
CGACGACTCGCAGATTCGCAGCCTGTTGTGCGACTGCCTTGCAGACTTCGGCATGACGACCGCGCAAGCCGGCACCGGTG
CGGAAATGCATCTCGCGCTCGGGGAGGGCGGCTTCGATCTCGTGGTGCTCGACCTGATGCTGCCGGACGACGACGGCCTC
AATCTCTGCCGCGAGATTCGTGCGACCTCCGAGATTCCGTTGATCATCCTGACCGCGCGCGGCGAGATGACCGACCGGAT
CGTCGGACTGGAACTCGGCGCCGACGACTATATCGTCAAGCCGTTCGAACCGCGTGAACTGGTCGCGCGCATCCAGACGA
TCCTGCGCCGCGTGCGCGCGCAAACGCAAGGCCGCACGAGGGCGCAGGAGGAAAGCCGCTTCGCCGGATGGCGGCTTCAC
CAGATCGGCCGCCACCTGATTGCGGCCGACAACACGGTCATTCCATTGTCGAACGCGGAATTTCGCCTGCTCAATGCGTT
CCTCGCCGCGCCGGGGCGAGTACTGAGCCGCGAGTACCTGATGGATACCGCGCGCGGCAAGTCGATCGACACGTTCGACC
GCAGCATCGACGTGCAGATCTCACGCTTGCGTCAGAAGCTGCGCGAGGACATCAAGGAGCCGCGCCTGATTCGCACGATT
CGCGGGGAAGGCTACATGCTGGATGTCGGGCATCGTTAG

Upstream 100 bases:

>100_bases
ATCCCGATTTTTCCCGATGACCTTGTAGGGCAAGGTGCCGGGGCAATTATTTCAACGCTGCAACAATTCGTGCAAAAAGC
CCTTATATTGGCGGGCAATA

Downstream 100 bases:

>100_bases
GTGTGCGTGCTGATCGTTGCAGCCGATCGTCGGCATGCGATGCAAGCAGCGCGGTGGGCTGTGTGCCGGCACCGCCATCA
TCGACCCGATCAATCGCTCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSAGDISPPQHRRQDAVNKAIRILVVDDDSQIRSLLCDCLADFGMTTAQAGTGAEMHLALGEGGFDLVVLDLMLPDDDGL
NLCREIRATSEIPLIILTARGEMTDRIVGLELGADDYIVKPFEPRELVARIQTILRRVRAQTQGRTRAQEESRFAGWRLH
QIGRHLIAADNTVIPLSNAEFRLLNAFLAAPGRVLSREYLMDTARGKSIDTFDRSIDVQISRLRQKLREDIKEPRLIRTI
RGEGYMLDVGHR

Sequences:

>Translated_252_residues
MSAGDISPPQHRRQDAVNKAIRILVVDDDSQIRSLLCDCLADFGMTTAQAGTGAEMHLALGEGGFDLVVLDLMLPDDDGL
NLCREIRATSEIPLIILTARGEMTDRIVGLELGADDYIVKPFEPRELVARIQTILRRVRAQTQGRTRAQEESRFAGWRLH
QIGRHLIAADNTVIPLSNAEFRLLNAFLAAPGRVLSREYLMDTARGKSIDTFDRSIDVQISRLRQKLREDIKEPRLIRTI
RGEGYMLDVGHR
>Mature_251_residues
SAGDISPPQHRRQDAVNKAIRILVVDDDSQIRSLLCDCLADFGMTTAQAGTGAEMHLALGEGGFDLVVLDLMLPDDDGLN
LCREIRATSEIPLIILTARGEMTDRIVGLELGADDYIVKPFEPRELVARIQTILRRVRAQTQGRTRAQEESRFAGWRLHQ
IGRHLIAADNTVIPLSNAEFRLLNAFLAAPGRVLSREYLMDTARGKSIDTFDRSIDVQISRLRQKLREDIKEPRLIRTIR
GEGYMLDVGHR

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=44.8717948717949, Blast_Score=188, Evalue=3e-49,
Organism=Escherichia coli, GI1790863, Length=225, Percent_Identity=38.6666666666667, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=40.6926406926407, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=38.8646288209607, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=38.7665198237885, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=37.6623376623377, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1790860, Length=183, Percent_Identity=42.0765027322404, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=40.3508771929825, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=33.1896551724138, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=33.1858407079646, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=34.9775784753363, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=35.5263157894737, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=30.4347826086957, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=32.4561403508772, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790299, Length=125, Percent_Identity=35.2, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788550, Length=138, Percent_Identity=31.8840579710145, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788191, Length=125, Percent_Identity=31.2, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790437, Length=156, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28267; Mature: 28136

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGDISPPQHRRQDAVNKAIRILVVDDDSQIRSLLCDCLADFGMTTAQAGTGAEMHLAL
CCCCCCCCCHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GEGGFDLVVLDLMLPDDDGLNLCREIRATSEIPLIILTARGEMTDRIVGLELGADDYIVK
CCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCCCEEC
PFEPRELVARIQTILRRVRAQTQGRTRAQEESRFAGWRLHQIGRHLIAADNTVIPLSNAE
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHEECCCEEEECCCCH
FRLLNAFLAAPGRVLSREYLMDTARGKSIDTFDRSIDVQISRLRQKLREDIKEPRLIRTI
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
RGEGYMLDVGHR
CCCCEEEECCCC
>Mature Secondary Structure 
SAGDISPPQHRRQDAVNKAIRILVVDDDSQIRSLLCDCLADFGMTTAQAGTGAEMHLAL
CCCCCCCCHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GEGGFDLVVLDLMLPDDDGLNLCREIRATSEIPLIILTARGEMTDRIVGLELGADDYIVK
CCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCCCEEC
PFEPRELVARIQTILRRVRAQTQGRTRAQEESRFAGWRLHQIGRHLIAADNTVIPLSNAE
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHEECCCEEEECCCCH
FRLLNAFLAAPGRVLSREYLMDTARGKSIDTFDRSIDVQISRLRQKLREDIKEPRLIRTI
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
RGEGYMLDVGHR
CCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]