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The map label for this gene is map [H]

Identifier: 78065733

GI number: 78065733

Start: 1195397

End: 1196203

Strand: Direct

Name: map [H]

Synonym: Bcep18194_A4261

Alternate gene names: 78065733

Gene position: 1195397-1196203 (Clockwise)

Preceding gene: 78065732

Following gene: 78065736

Centisome position: 32.36

GC content: 66.05

Gene sequence:

>807_bases
ATGGCGAAGCGAGAAATCCCGATCCGCGGCGCCGCGGAAATCGCCAAGTCGCGCGAAGCCGCGAAGCTCGCGTCGCAGGT
GCTGACGATGATCACCGAGCACGTGAAGCCGGGTGTCACCACCGACGAGCTGGACGTGCTCTGCCGCAACTACATCGTCG
ACGTGCTCGGTGCGATCCCGGCGAACATCGGCTACCACGGTTATCCGAAGACGCTCTGCACGTCGGTCAATCACGTGGTG
TGTCACGGCATTCCGACGTCGCGGCCGCTGCGCGACGGCGACATCGTGAACCTCGACATTGCGGTGATCAAGGACGGCTG
GTTCGGCGATACGAGCCGCATGTATTTCGTCGGCGAACCGAACGAGCTCGCGCGTCGGCTTGTCGCGACGACCTATGAGG
CGATGCACGCGGGCATTCGCGCGGTGCGTCCGGGCGCAACGCTCGGCGACGTCGGCTACGCGATCCAGCAGGTCGCGCAT
CGCGAAGGATTCAGCGTGGTTCGCGAGTACTGCGGGCACGGCATCGGCGATGTCTATCACGACGAGCCGCAGGTGCTTCA
CTACGGCCGCCCGGGCACCGGCGTGCCGCTCCGGCCGGGGATGATCTTCACGATCGAGCCGATGCTCAACGCAGGCAAGC
GCGACACGCGCATGCTGGCGGACGGCTGGACGGTCGTCACGAAGGACCATTCGCTGTCGGCGCAATGGGAGCACATGGTC
GTGGTGACCGAGACGGGCTTCGAGGTGCTGTCCGAGGACGTGAAGCCGCAGGCGTTTCCGGTGCTGTCCGGCACGCACGC
CGCCTGA

Upstream 100 bases:

>100_bases
CCTACGGGGACATCTGCCGGATGCTGATCGAGGCCGAAGCGCGGGGCGGTGAAGCGGGGCCGGCGGAATCGGTCGAGCAC
GGCATCGAGCAGGTGGCGTA

Downstream 100 bases:

>100_bases
TATCTGCAGTGCGCCGCGAACGGCGGTGCGGCGTCACAGTGAAACGGGCCCCTTTGCGGGGCCCGTTTCGTTTTCGTTCC
AGGTTGCGCGGCGCGATTTA

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAKREIPIRGAAEIAKSREAAKLASQVLTMITEHVKPGVTTDELDVLCRNYIVDVLGAIPANIGYHGYPKTLCTSVNHVV
CHGIPTSRPLRDGDIVNLDIAVIKDGWFGDTSRMYFVGEPNELARRLVATTYEAMHAGIRAVRPGATLGDVGYAIQQVAH
REGFSVVREYCGHGIGDVYHDEPQVLHYGRPGTGVPLRPGMIFTIEPMLNAGKRDTRMLADGWTVVTKDHSLSAQWEHMV
VVTETGFEVLSEDVKPQAFPVLSGTHAA

Sequences:

>Translated_268_residues
MAKREIPIRGAAEIAKSREAAKLASQVLTMITEHVKPGVTTDELDVLCRNYIVDVLGAIPANIGYHGYPKTLCTSVNHVV
CHGIPTSRPLRDGDIVNLDIAVIKDGWFGDTSRMYFVGEPNELARRLVATTYEAMHAGIRAVRPGATLGDVGYAIQQVAH
REGFSVVREYCGHGIGDVYHDEPQVLHYGRPGTGVPLRPGMIFTIEPMLNAGKRDTRMLADGWTVVTKDHSLSAQWEHMV
VVTETGFEVLSEDVKPQAFPVLSGTHAA
>Mature_267_residues
AKREIPIRGAAEIAKSREAAKLASQVLTMITEHVKPGVTTDELDVLCRNYIVDVLGAIPANIGYHGYPKTLCTSVNHVVC
HGIPTSRPLRDGDIVNLDIAVIKDGWFGDTSRMYFVGEPNELARRLVATTYEAMHAGIRAVRPGATLGDVGYAIQQVAHR
EGFSVVREYCGHGIGDVYHDEPQVLHYGRPGTGVPLRPGMIFTIEPMLNAGKRDTRMLADGWTVVTKDHSLSAQWEHMVV
VTETGFEVLSEDVKPQAFPVLSGTHAA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=253, Percent_Identity=43.0830039525692, Blast_Score=218, Evalue=4e-57,
Organism=Homo sapiens, GI40385867, Length=247, Percent_Identity=39.2712550607287, Blast_Score=204, Evalue=7e-53,
Organism=Escherichia coli, GI1786364, Length=247, Percent_Identity=56.2753036437247, Blast_Score=297, Evalue=6e-82,
Organism=Escherichia coli, GI1789275, Length=285, Percent_Identity=25.6140350877193, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=252, Percent_Identity=38.8888888888889, Blast_Score=193, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6323273, Length=247, Percent_Identity=42.5101214574899, Blast_Score=217, Evalue=2e-57,
Organism=Drosophila melanogaster, GI21355531, Length=248, Percent_Identity=41.9354838709677, Blast_Score=205, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24583427, Length=246, Percent_Identity=36.5853658536585, Blast_Score=184, Evalue=5e-47,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29251; Mature: 29120

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKREIPIRGAAEIAKSREAAKLASQVLTMITEHVKPGVTTDELDVLCRNYIVDVLGAIP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ANIGYHGYPKTLCTSVNHVVCHGIPTSRPLRDGDIVNLDIAVIKDGWFGDTSRMYFVGEP
CCCCCCCCCHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEECH
NELARRLVATTYEAMHAGIRAVRPGATLGDVGYAIQQVAHREGFSVVREYCGHGIGDVYH
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCC
DEPQVLHYGRPGTGVPLRPGMIFTIEPMLNAGKRDTRMLADGWTVVTKDHSLSAQWEHMV
CCCCEEEECCCCCCCCCCCCEEEEECHHHCCCCCCCEEEECCEEEEEECCCCCCCEEEEE
VVTETGFEVLSEDVKPQAFPVLSGTHAA
EEECCCHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure 
AKREIPIRGAAEIAKSREAAKLASQVLTMITEHVKPGVTTDELDVLCRNYIVDVLGAIP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ANIGYHGYPKTLCTSVNHVVCHGIPTSRPLRDGDIVNLDIAVIKDGWFGDTSRMYFVGEP
CCCCCCCCCHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEECH
NELARRLVATTYEAMHAGIRAVRPGATLGDVGYAIQQVAHREGFSVVREYCGHGIGDVYH
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCC
DEPQVLHYGRPGTGVPLRPGMIFTIEPMLNAGKRDTRMLADGWTVVTKDHSLSAQWEHMV
CCCCEEEECCCCCCCCCCCCEEEEECHHHCCCCCCCEEEECCEEEEEECCCCCCCEEEEE
VVTETGFEVLSEDVKPQAFPVLSGTHAA
EEECCCHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]